Response to Comment on "Pairing and Phase Separation in a Polarized Fermi Gas"

Zwierlein and Ketterle rely on subjective arguments and fail to recognize important differences in physical parameters between our experiment and theirs. We stand by the conclusions of our original report

An acoustic analog to the dynamical Casimir effect in a Bose-Einstein condensate

We have realized an acoustic analog to the Dynamical Casimir effect. The density of a trapped Bose-Einstein condensate is modulated by changing the trap stiffness. We observe the creation of correlated excitations with equal and opposite momenta, and show that for a well defined modulation frequency, the frequency of the excitations is half that of the trap modulation frequency.Comment: Includes supplemental informatio

Pairing and Phase Separation in a Polarized Fermi Gas

We report the observation of a pairing in a number polarized two-component gas of atomic fermions. Beyond a critical polarization, the gas separates into a superfluid paired core surrounded by a shell of normal unpaired fermions. The critical polarization diminishes with decreasing attractive interaction. We also measure the parameter \beta = 0.54 (5) describing the universal energy of a strongly interacting Fermi gas, and find good agreement with most recent theory. These results are relevant to predictions of exotic new phases of quark matter and of strongly magnetized superconductors

Conversion of an Atomic Fermi Gas to a Long-Lived Molecular Bose Gas

We have converted an ultracold Fermi gas of $^6$Li atoms into an ultracold gas of $^6$Li$_2$ molecules by adiabatic passage through a Feshbach resonance. Approximately $1.5 \times 10^5$ molecules in the least-bound, $v = 38$, vibrational level of the X$^1 \Sigma ^+_g$ singlet state are produced with an efficiency of 50%. The molecules remain confined in an optical trap for times of up to 1 s before we dissociate them by a reverse adiabatic sweep.Comment: Accepted for publication in Phys. Rev. Letter

Spin-Imbalance in a One-Dimensional Fermi Gas

Superconductivity and magnetism generally do not coexist. Changing the relative number of up and down spin electrons disrupts the basic mechanism of superconductivity, where atoms of opposite momentum and spin form Cooper pairs. Nearly forty years ago Fulde and Ferrell and Larkin and Ovchinnikov proposed an exotic pairing mechanism (FFLO) where magnetism is accommodated by formation of pairs with finite momentum. Despite intense theoretical and experimental efforts, however, polarized superconductivity remains largely elusive. Here we report experimental measurements of density profiles of a two spin mixture of ultracold 6Li atoms trapped in an array of one dimensional (1D) tubes, a system analogous to electrons in 1D wires. At finite spin imbalance, the system phase separates with an inverted phase profile in comparison to the three-dimensional case. In 1D we find a partially polarized core surrounded by wings composed of either a completely paired BCS superfluid or a fully polarized Fermi gas, depending on the degree of polarization. Our observations are in quantitative agreement with theoretical calculations in which the partially polarized phase is found to be a 1D analogue of the FFLO state. This study demonstrates how ultracold atomic gases in 1D may be used to create non-trivial new phases of matter, and also paves the way for direct observation and further study of the FFLO phase.Comment: 30 pages, 7 figure

Effects of fluoxetine on functional outcomes after acute stroke (FOCUS): a pragmatic, double-blind, randomised, controlled trial

Background Results of small trials indicate that fluoxetine might improve functional outcomes after stroke. The FOCUS trial aimed to provide a precise estimate of these effects. Methods FOCUS was a pragmatic, multicentre, parallel group, double-blind, randomised, placebo-controlled trial done at 103 hospitals in the UK. Patients were eligible if they were aged 18 years or older, had a clinical stroke diagnosis, were enrolled and randomly assigned between 2 days and 15 days after onset, and had focal neurological deficits. Patients were randomly allocated fluoxetine 20 mg or matching placebo orally once daily for 6 months via a web-based system by use of a minimisation algorithm. The primary outcome was functional status, measured with the modified Rankin Scale (mRS), at 6 months. Patients, carers, health-care staff, and the trial team were masked to treatment allocation. Functional status was assessed at 6 months and 12 months after randomisation. Patients were analysed according to their treatment allocation. This trial is registered with the ISRCTN registry, number ISRCTN83290762. Findings Between Sept 10, 2012, and March 31, 2017, 3127 patients were recruited. 1564 patients were allocated fluoxetine and 1563 allocated placebo. mRS data at 6 months were available for 1553 (99·3%) patients in each treatment group. The distribution across mRS categories at 6 months was similar in the fluoxetine and placebo groups (common odds ratio adjusted for minimisation variables 0·951 [95% CI 0·839–1·079]; p=0·439). Patients allocated fluoxetine were less likely than those allocated placebo to develop new depression by 6 months (210 [13·43%] patients vs 269 [17·21%]; difference 3·78% [95% CI 1·26–6·30]; p=0·0033), but they had more bone fractures (45 [2·88%] vs 23 [1·47%]; difference 1·41% [95% CI 0·38–2·43]; p=0·0070). There were no significant differences in any other event at 6 or 12 months. Interpretation Fluoxetine 20 mg given daily for 6 months after acute stroke does not seem to improve functional outcomes. Although the treatment reduced the occurrence of depression, it increased the frequency of bone fractures. These results do not support the routine use of fluoxetine either for the prevention of post-stroke depression or to promote recovery of function. Funding UK Stroke Association and NIHR Health Technology Assessment Programme