8,769 research outputs found
Partner selection supported by opaque reputation promotes cooperative behavior
Reputation plays a major role in human societies, and it has been proposed as an explanation for the evolution of cooperation. While the majority of previous studies equates reputation with a transparent and complete history of players' past decisions, in real life, reputations are often ambiguous and opaque. Using web-based experiments, we explore the extent to which opaque reputation works in isolating defectors, with and without partner selection opportunities. Our results show that low reputation works as a signal of untrustworthiness, whereas medium or high reputation are not taken into account by participants for orienting their choices. We also find that reputation without partner selection does not promote cooperative behavior; that is, defectors do not turn into cooperators only for the sake of getting a positive reputation. Finally, in a third study, we find that, when reputation is pivotal to selection, then a substantial proportion of would-be defectors turn into cooperators. Taken together, these results provide insights on the characteristics of reputation and on the way in which humans make use of it when selecting partners but also when knowing that they will be selected
Photoaging in outdoor workers: marker of cumulative uvr exposure, risk factor or occupational disease?
Effects of osmotic and thermal shock on the invasive aquatic mudsnail Potamopyrgus antipodarum: Mortality and physiology under stressful conditions
Invasive freshwater species, such as the exotic mollusc Potamopyrgus antipodarum (New Zealand mudsnail), can frequently survive under harsh conditions, including brackish and hypoxic environments. We experimentally assessed the effects of osmotic (0, 10, 20, 25 and 30 psu) and thermal (20 °C) shock on mortality, activity and physiology of P. antipodarum collected at Capitol Lake, Olympia, Washington, USA, during winter and spring seasons when environmental temperature was 5 and 10 °C respectively. We measured standard metabolic rate and enzymatic activities (malate dehydrogenase, lactate dehydrogenase, alanopine dehydrogenase) in snails after a 10-day acclimation period at high salinity. Significantly higher mortalities were observed at higher salinities; the strongest effects occurred on snails collected at the end of winter, and exposed to 30 psu and 20 °C (100% mortality in 3 days). When snails were collected during the spring, 100% mortality was observed after 40 days at 30 psu and 20 °C. Standard metabolic rates were significantly lower when snails were exposed to salinities of 25 and 30 psu, even after 10 days of acclimation. Enzymatic activities showed small but significant declines after 10 days at 30 psu reflecting the declines observed in overall metabolism. The physiological tolerances to temperature and salinity displayed by this population of P. antipodarum make its eradication from Capital Lake difficult to achieve.Fil: Paolucci, Esteban Marcelo. Consejo Nacional de Investigaciones CientÃficas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. Museo Argentino de Ciencias Naturales "Bernardino Rivadavia"; ArgentinaFil: Thuesen, Erik V.. The Evergreen State College; Estados Unido
Scaling of a large-scale simulation of synchronous slow-wave and asynchronous awake-like activity of a cortical model with long-range interconnections
Cortical synapse organization supports a range of dynamic states on multiple
spatial and temporal scales, from synchronous slow wave activity (SWA),
characteristic of deep sleep or anesthesia, to fluctuating, asynchronous
activity during wakefulness (AW). Such dynamic diversity poses a challenge for
producing efficient large-scale simulations that embody realistic metaphors of
short- and long-range synaptic connectivity. In fact, during SWA and AW
different spatial extents of the cortical tissue are active in a given timespan
and at different firing rates, which implies a wide variety of loads of local
computation and communication. A balanced evaluation of simulation performance
and robustness should therefore include tests of a variety of cortical dynamic
states. Here, we demonstrate performance scaling of our proprietary Distributed
and Plastic Spiking Neural Networks (DPSNN) simulation engine in both SWA and
AW for bidimensional grids of neural populations, which reflects the modular
organization of the cortex. We explored networks up to 192x192 modules, each
composed of 1250 integrate-and-fire neurons with spike-frequency adaptation,
and exponentially decaying inter-modular synaptic connectivity with varying
spatial decay constant. For the largest networks the total number of synapses
was over 70 billion. The execution platform included up to 64 dual-socket
nodes, each socket mounting 8 Intel Xeon Haswell processor cores @ 2.40GHz
clock rates. Network initialization time, memory usage, and execution time
showed good scaling performances from 1 to 1024 processes, implemented using
the standard Message Passing Interface (MPI) protocol. We achieved simulation
speeds of between 2.3x10^9 and 4.1x10^9 synaptic events per second for both
cortical states in the explored range of inter-modular interconnections.Comment: 22 pages, 9 figures, 4 table
In vitro percutaneous penetration of polycyclic aromatic hydrocarbons from sunscreen creams
Background: Dermal exposure to Polycyclic Aromatic Hydrocarbons (PAHs) affects many outdoor workers such as asphalt workers. Usually the use of sunscreen creams is suggested to protect them from UV radiation. However sunscreen could prevent or facilitate dermal absorption of industrial chemicals.
Objectives: The aim of the study was to assess percutaneous penetration of anthracene using 2 different sunscreen creams as vehicle.
Methods: In vitro permeation experiments were carried out using standardized in vitro methods with static diffusion cells. Excised human skin prepared to approximately 350 mm thickness was fixed on the diffusion cells. The receiving phase was a saline solution with 6% PEG 20. The 2 sunscreen creams (one lipophilic and one hydrophilic) were applied uniformly (2mg/cm2) on the skin mounted on the diffusion cell. After 20 minutes, a solution of anthracene and artificial sweat was added. Analysis of anthracene in the receptor samples was carried out by beta counter analyzer (Packard).
Results: Results did not show a percutaneous penetration of anthracene from sunscreen creams while in previous studies in vitro percutaneous penetration of anthracene was demonstrated using the same methodology.
Discussion and Conclusion: The use of sunscreen creams among outdoor workers, would not seem to enhance percutaneous penetration of PAHs. On the contrary it seems to be able to reduce dermal absorption of anthracene in the workplace
Quale sorveglianza sanitaria per gli esposti all’amianto? L’esperienza dell’Università di Siena.
Simulations of working memory spiking networks driven by short-term plasticity
Working Memory (WM) is a cognitive mechanism that enables temporary holding and manipulation of information in the human brain. This mechanism is mainly characterized by a neuronal activity during which neuron populations are able to maintain an enhanced spiking activity after being triggered by a short external cue. In this study, we implement, using the NEST simulator, a spiking neural network model in which the WM activity is sustained by a mechanism of short-term synaptic facilitation related to presynaptic calcium kinetics. The model, which is characterized by leaky integrate-and-fire neurons with exponential postsynaptic currents, is able to autonomously show an activity regime in which the memory information can be stored in a synaptic form as a result of synaptic facilitation, with spiking activity functional to facilitation maintenance. The network is able to simultaneously keep multiple memories by showing an alternated synchronous activity which preserves the synaptic facilitation within the neuron populations holding memory information. The results shown in this study confirm that a WM mechanism can be sustained by synaptic facilitation
Selection and spectral matching of recorded ground motions for seismic fragility analyses
Ground motion selection is one of the most important phases in the derivation of fragility curves through non-linear dynamic analyses. In this context, an easy-to-use software, namely S&M—Select & Match, has been adopted for the selection and spectral matching of recorded ground motions approaching a target response spectrum in a broad period range. In this paper, after a brief description of the key features of the S&M tool, two sets of 125 accelerograms, separately for stiff (i.e. site classes A and B according to the Italian code) and soft soil (i.e. site classes C and D) conditions, have been selected on the basis of the elastic design spectra of the Italian seismic code defined for different return periods. The selected ground motions have been analysed and used for non-linear dynamic analysis of a case study representative of a common Italian RC building type designed only to gravity loads. Results have been analysed in order to check the capability of the considered signals to adequately cover all the damage levels generally adopted in seismic risk analyses, as well as the effects on seismic response due to the selection criteria permitted by the proposed tool
Fully superconducting josephson bolometers for gigahertz astronomy
The origin and the evolution of the universe are concealed in the evanescent diffuse extragalactic background radiation (DEBRA). To reveal these signals, the development of innovative ultra-sensitive bolometers operating in the gigahertz band is required. Here, we review the design and experimental realization of two bias-current-tunable sensors based on one dimensional fully superconducting Josephson junctions: the nanoscale transition edge sensor (nano-TES) and the Josephson escape sensor (JES). In particular, we cover the theoretical basis of the sensors operation, the device fabrication, their experimental electronic and thermal characterization and the deduced detection performance. Indeed, the nano-TES promises a state-of-the-art noise equivalent power (NEP) of about 5 × 10−20 W/√Hz, while the JES active region is expected to show an unprecedented NEP of the order of 10−25 W/√Hz. Therefore, the nano-TES and JES are strong candidates to push radio astronomy to the next level
Tracing groundwater circulation in a valuable mineral water basin with geochemical and isotopic tools: the case of FERRARELLE, Riardo basin, Southern Italy
The Riardo basin hosts groundwater exploited for the production of high quality, naturally sparkling, bottled water (e.g., Ferrarelle water), and circulating in a system constituted by highly fractured Mesozoic carbonates, overlain by more impervious volcanic rocks of the Roccamonfina complex. The two formations are locally in hydraulic connection and dislocated by deep-rooted faults. The study aimed at elucidating groundwater origin and circulation, using isotopic tracers (δ18O, δ2H, δ11B and 87Sr/86Sr) coupled to groundwater dating (Tritium, CFCs and SF6). Besides recharge by local precipitation over the Riardo hydrogeological basin, stable isotope ratios in water indicated an extra-basin recharge, likely from the elevated surrounding carbonate reliefs (e.g., Maggiore and Matese Mts.). The mineralization process, promoted by the deep CO2 flux, controls the B and Sr contents. However, their isotopic ratios did not allow discriminating between circulation in the volcanic and in the carbonate aquifers, as in the latter the isotopic composition differed from the original marine signature. Groundwater model ages ranged from ~ 30 years for the volcanic endmember to > 70 years for the deep, mineralized end-member, with longer circuits recharged at higher elevations. Overall, the results of this study were particularly relevant for mineral water exploitation. A recharge from outside the hydrogeological basin could be evidenced, especially for the more mineralized and valuable groundwater, and an active recent recharge was detected for the whole Riardo system. Both findings will contribute to the refinement of the hydrogeological model and water budget, and to a sustainable development of the resource
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