9 research outputs found
Analysis of national Jatropha biodiesel programme in Senegal
- Author
- Achten WMJ Verchot L, Franken YJ, et al.
- Augustus GDPS Jayabalan M, Seiler GJ
- Francis G Edinger R, Becker K
- Fukuda H Kondo A, Noda H
- Gubitz GM Mittelbach M, Trabi M
- Jain S Sharma MP
- Kandpal JB Madan M
- Kant P Wu S
- Kumar A Sharma S
- Openshaw K
- Pandey VC Singh K, Singh JS, et al.
- Soumanou MM Bornscheuer UT
- Srivastava A Prasad R
- Sujatha M Reddy TP, Mahasi MJ
- Vicente G Coteron A, Martinez M, et al.
- Zahawi RA
- Publication venue
- 'American Institute of Mathematical Sciences (AIMS)'
- Publication date
- 01/01/2016
- Field of study
Leaf area estimation in <i>Jatropha curcas</i> (L.): an update
- Author
- Alburquerque N García-Almodóvar RC, Valverde JM, et al.
- Antunes WC Pompelli MF, Carretero DM, et al.
- Blanco FF Folegatti MV
- Chel A Kaushik G
- Collins SL
- Contran N Chessa L, Lubino M, et al.
- Cristofori V Rouphael Y, Mendoza-de Gyves E, et al.
- Cumming G Fidler F, Vaux DL
- Divakara BN Upadhyaya HD, Wani SP, et al.
- Díaz S Kattge J, Cornelissen JHC, et al.
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- Gutiérrez-Antonio C Romero-Izquierdo AG, Gómez-Castro FI, et al.
- Kandiannan K Parthasarathy U, Krishnamurthy KS, et al.
- Keesstra SD Bouma J, Wallinga J, et al.
- Keramatlou I Sharifani M, Sabouri H, et al.
- Kirkman LK Sharitz RR
- Liu Z Zhu Y, Li F, et al.
- Mardhiah HH Ong HC, Masjuki HH, et al.
- Openshaw K
- Pandey VC Singh K, Singh JS, et al.
- Peksen E
- Pompelli MF Antunes WC, Ferreira DTRG, et al.
- Pompelli MF Ferreira DTRG, Cavalcante PPGS, et al.
- Silitonga AS Hassan MH, Ong HC, et al.
- Souza MC Amaral CL
- Steel M Penny D
- Tondjo K Brancheriau L, Sabatier SA, et al.
- Villar R Ruiz-Robleto J, Ubera JL, et al.
- Walther BA Moore JL
- Zhang L Pan L
- Zuur AF Elena NI, Elphick CS
- Publication venue
- 'American Institute of Mathematical Sciences (AIMS)'
- Publication date
- 01/01/2018
- Field of study
Plant probiotic bacteria: solutions to feed the world
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- Abou-Shanab RA Angle JS, Delorme TA, et al.
- Ahmad M Zahir ZA, Khalid M, et al.
- Ahmed E Holmstrom SJ
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- Araus J Li J, Parry M, et al.
- Araújo FF Henning AA, Hungria M
- Arkhipova TN Prinsen E, Veselov SU, et al.
- Arora NK Khare E, Oh JH, et al.
- Asaf S Khan MA, Khan AL, et al.
- Beneduzi A Ambrosini A, Passaglia LM
- Beneduzi A Peres D, Vargas LK, et al.
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- Berge O Heulin T, Achouak W, et al.
- Bhattacharyya PN Jha DK
- Brewin NJ
- Burd GI Dixon DG, Glick BR
- Béné C Barange M, Subasinghe R, et al.
- Calvo J Calvente V, de Orellano ME, et al.
- Chattopadhyay A Bhatnagar NB, Bhatnagar R
- Costacurta A Vanderleyden J
- Dastager SG Deepa CK, Pandey A
- Durán P Acuña JJ, Jorquera MA, et al.
- Egamberdiyeva D
- El-Akhal MR Rincon A, Coba de la Pena T, et al.
- El-Tarabily KA
- El-Tarabily KA Sykes ML, Kurtböke ID, et al.
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- Flores-Felix JD Menendez E, Rivera LP, et al.
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- Flores-Félix JD Marcos-García M, Silva LR, et al.
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- Gamalero E Glick BR
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- García-Fraile P Menéndez E, Rivas R
- Glick BR
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- Kong Z Glick BR, Duan J, et al.
- Lee SW Lee SH, Balaraju K, et al.
- Li H Ding X, Wang C, et al.
- Liddycoat SM Greenberg BM, Wolyn DJ
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- Liu FP Liu HQ, Zhou HL, et al.
- Ma W Penrose DM, Glick BR
- Ma Y Rajkumar M, Freitas H
- Magnucka EG Pietr SJ
- Maksimov IV Abizgil'dina RR, Pusenkova LI
- Malusá E Vassilev N
- Moulin L Munive A, Dreyfus B, et al.
- Muñoz-Rojas J Caballero-Mellado J
- Nagahama K Ogawa T, Fujii T, et al.
- Neilands JB
- Oldroyd GE Downie JA
- Ortiz-Castro R Valencia-Cantero E, López-Bucio J
- Pal KK Tilak KVBR, Saxcna AK, et al.
- Panda P Chakraborty S, Ray DP, et al.
- Pastor N Masciarelli O, Fischer S, et al.
- Paul D Nair S
- Pawlowski K Demchenko KN
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- Pimentel D
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- Santi C Bogusz D, Franche C
- Schachtman DP Reid RJ, Ayling SM
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- Sharma IP Sharma AK
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- Sheng XF
- Sheng XF He LY
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- Singh RP Jha PN
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- Spaepen S Vanderleyden J, Remans R
- Subhashini DV
- Suzaki T Kawaguchi M
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- Thomashow LS
- Tilman D Balzer C, Hill J, et al.
- Trewavas A
- Vejan P Abdullah R, Khadiran T, et al.
- Verma VC Singh SK, Prakash S
- Vessey JK Pawlowski K, Bergman B
- Wang W Vinocur B, Altman A
- Wani SA Chand S, Ali T
- Xu S Kim BS
- Yadegari M Rahmani HA, Noormohammadi G, et al.
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- Yu X Ai C, Xin L, et al.
- Zaidi A Khan M, Ahemad M, et al.
- Zerrouk IZ Benchabane M, Khelifi L, et al.
- Zhang C Kong F
- Zubair M Shakir M, Ali Q, et al.
- Publication venue
- 'American Institute of Mathematical Sciences (AIMS)'
- Publication date
- 01/01/2017
- Field of study
Safety of Nonsteroidal Anti-inflammatory Drugs in Major Gastrointestinal Surgery: A Prospective, Multicenter Cohort Study
- Author
- Abbas Z
- Abburu S
- Abdelhadi M
- Abdikadir HR
- Abdulmajid A
- Abid A
- Abid H
- Abuhussein N
- Abul MH
- Acquaah F
- Acres M
- Adams R
- Adams RD
- Adebayo AA
- Adeleja I
- Adjei H
- Afzal Z
- Agarwal V
- Ahern N
- Ahmad K
- Ahmad S
- Ahmed F
- Ahmed H
- Ahmed M
- Ahmed N
- Ahmed S
- Ahmed S
- Ahn JS
- Aidoo-Micah GE
- Aildasani L
- Aithie JM
- Akhtar S
- Al-Mousawi A
- Al-Obaedi O
- Al-Obaedi O
- Al-Robeye A
- Ali A
- Ali B
- Ali H
- Ali M
- Ali S
- Alizadeh M
- Allan C
- Allen JLY
- Allot R
- Allot R
- Allot R
- Amajuoyi A
- Amin H
- Amin H
- Amin O
- Amphlett AH
- Anandarajah C
- Anderson L
- Anderson LB
- Anderson SM
- Ang A
- Angelov S
- Anilkumar A
- Anim-Addo N
- Ansari N
- Antoniou I
- Archer CH
- Arif T
- Arif T
- Asbjoernsen CA
- Ashfaq U
- Ashken L
- Ashraf S
- Ashraf SF
- Ashton AJ
- Ashwood J
- Aslanyan A
- Asmadi A
- Assadullah S
- Atayi A
- Atraszkiewicz BA
- Attalla M
- Austreng L
- Auyoung E
- Avery P
- Axelson T
- Aziz H
- Aziz N
- Baker AN
- Bakewell ZR
- Bakhsh A
- Bakhsh A
- Balaji S
- Balian V
- Balian V
- Balian V
- Bamgbose FA
- Barai I
- Barnes J
- Barrow TR
- Barthorpe AE
- Bartlett J
- Bartlett RD
- Barton EC
- Bassam N
- Bassett J
- Bassiony S
- Bath MF
- Batho A
- Batt E
- Bazeer HZ
- Beckett J
- Beecroft S
- Behar N
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- Bergara T
- Bernstein I
- Bethell GS
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- Bhangu A
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- Blege HK
- Blessed R
- Bloomer J
- Bloomfield T
- Blore CD
- Bolton L
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- Bonsu S
- Bookless LR
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- Botchey S
- Boulton AJ
- Boxall N
- Boyle J
- Braganza L
- Brathwaite-Shirley C
- Bravo M
- Brecher J
- Bremner RH
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- Chapman SJ
- Charalambos MA
- Charalambous G
- Charania A
- Charavanamuttu V
- Chaudhary M
- Chaudhry FI
- Chaudhry WW
- Cheema H
- Chen JH
- Chen M
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- Chervenkoff J
- Cheskes L
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- Chhabra A
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- Chilvers NJ
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- Chisholm EG
- Chitnis AR
- Chiu SM
- Chong BF
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- Chrastek D
- Chua EY
- Chung A
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- Clark IJ
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- Coates A
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2017
- Field of study
Background
Significant safety concerns remain surrounding the use of nonsteroidal anti-inflammatory drugs (NSAIDs) following gastrointestinal surgery, leading to wide variation in their use. This study aimed to determine the safety profile of NSAIDs after major gastrointestinal surgery.
Methods
Consecutive patients undergoing elective or emergency abdominal surgery with a minimum one-night stay during a 3-month study period were eligible for inclusion. The administration of any NSAID within 3 days following surgery was the main independent variable. The primary outcome measure was the 30-day postoperative major complication rate, as defined by the Clavien–Dindo classification (Clavien–Dindo III–V). Propensity matching with multivariable logistic regression was used to produce odds ratios (OR) and 95 % confidence intervals.
Results
From 9264 patients, 23.9 % (n = 2212) received postoperative NSAIDs. The overall major complication rate was 11.5 % (n = 1067). Following propensity matching and adjustment, use of NSAIDs were not significantly associated with any increase in major complications (OR 0.90, 0.60–1.34, p = 0.560).
Conclusions
Early use of postoperative NSAIDs was not associated with an increase in major complications following gastrointestinal surgery
Population and fertility by age and sex for 195 countries and territories, 1950–2017: a systematic analysis for the Global Burden of Disease Study 2017
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- Yentür GK
- Yeshaneh A
- Yimer EM
- Yip P
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- Yotebieng M
- Younis MZ
- Yousefifard M
- Yu C
- Zadnik V
- Zaidi Z
- Zaman SB
- Zamani M
- Zare Z
- Zeleke MM
- Zenebe ZM
- Zerfu TA
- Zhang X
- Zhao X-J
- Zhou M
- Zhu J
- Zimsen SRM
- Zodpey S
- Zoeckler L
- Ärnlöv J
- Çavlin A
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2018
- Field of study
Background Population estimates underpin demographic and epidemiological research and are used to track progress on numerous international indicators of health and development. To date, internationally available estimates of population and fertility, although useful, have not been produced with transparent and replicable methods and do not use standardised estimates of mortality. We present single-calendar year and single-year of age estimates of fertility and population by sex with standardised and replicable methods. Methods We estimated population in 195 locations by single year of age and single calendar year from 1950 to 2017 with standardised and replicable methods. We based the estimates on the demographic balancing equation, with inputs of fertility, mortality, population, and migration data. Fertility data came from 7817 location-years of vital registration data, 429 surveys reporting complete birth histories, and 977 surveys and censuses reporting summary birth histories. We estimated age-specific fertility rates (ASFRs; the annual number of livebirths to women of a specified age group per 1000 women in that age group) by use of spatiotemporal Gaussian process regression and used the ASFRs to estimate total fertility rates (TFRs; the average number of children a woman would bear if she survived through the end of the reproductive age span [age 10–54 years] and experienced at each age a particular set of ASFRs observed in the year of interest). Because of sparse data, fertility at ages 10–14 years and 50–54 years was estimated from data on fertility in women aged 15–19 years and 45–49 years, through use of linear regression. Age-specific mortality data came from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017 estimates. Data on population came from 1257 censuses and 761 population registry location-years and were adjusted for underenumeration and age misreporting with standard demographic methods. Migration was estimated with the GBD Bayesian demographic balancing model, after incorporating information about refugee migration into the model prior. Final population estimates used the cohort-component method of population projection, with inputs of fertility, mortality, and migration data. Population uncertainty was estimated by use of out-of-sample predictive validity testing. With these data, we estimated the trends in population by age and sex and in fertility by age between 1950 and 2017 in 195 countries and territories. Findings From 1950 to 2017, TFRs decreased by 49·4% (95% uncertainty interval [UI] 46·4–52·0). The TFR decreased from 4·7 livebirths (4·5–4·9) to 2·4 livebirths (2·2–2·5), and the ASFR of mothers aged 10–19 years decreased from 37 livebirths (34–40) to 22 livebirths (19–24) per 1000 women. Despite reductions in the TFR, the global population has been increasing by an average of 83·8 million people per year since 1985. The global population increased by 197·2% (193·3–200·8) since 1950, from 2·6 billion (2·5–2·6) to 7·6 billion (7·4–7·9) people in 2017; much of this increase was in the proportion of the global population in south Asia and sub-Saharan Africa. The global annual rate of population growth increased between 1950 and 1964, when it peaked at 2·0%; this rate then remained nearly constant until 1970 and then decreased to 1·1% in 2017. Population growth rates in the southeast Asia, east Asia, and Oceania GBD super-region decreased from 2·5% in 1963 to 0·7% in 2017, whereas in sub-Saharan Africa, population growth rates were almost at the highest reported levels ever in 2017, when they were at 2·7%. The global average age increased from 26·6 years in 1950 to 32·1 years in 2017, and the proportion of the population that is of working age (age 15–64 years) increased from 59·9% to 65·3%. At the national level, the TFR decreased in all countries and territories between 1950 and 2017; in 2017, TFRs ranged from a low of 1·0 livebirths (95% UI 0·9–1·2) in Cyprus to a high of 7·1 livebirths (6·8–7·4) in Niger. The TFR under age 25 years (TFU25; number of livebirths expected by age 25 years for a hypothetical woman who survived the age group and was exposed to current ASFRs) in 2017 ranged from 0·08 livebirths (0·07–0·09) in South Korea to 2·4 livebirths (2·2–2·6) in Niger, and the TFR over age 30 years (TFO30; number of livebirths expected for a hypothetical woman ageing from 30 to 54 years who survived the age group and was exposed to current ASFRs) ranged from a low of 0·3 livebirths (0·3–0·4) in Puerto Rico to a high of 3·1 livebirths (3·0–3·2) in Niger. TFO30 was higher than TFU25 in 145 countries and territories in 2017. 33 countries had a negative population growth rate from 2010 to 2017, most of which were located in central, eastern, and western Europe, whereas population growth rates of more than 2·0% were seen in 33 of 46 countries in sub-Saharan Africa. In 2017, less than 65% of the national population was of working age in 12 of 34 high-income countries, and less than 50% of the national population was of working age in Mali, Chad, and Niger. Interpretation Population trends create demographic dividends and headwinds (ie, economic benefits and detriments) that affect national economies and determine national planning needs. Although TFRs are decreasing, the global population continues to grow as mortality declines, with diverse patterns at the national level and across age groups. To our knowledge, this is the first study to provide transparent and replicable estimates of population and fertility, which can be used to inform decision making and to monitor progress
Body mass index and complications following major gastrointestinal surgery: A prospective, international cohort study and meta-analysis
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- Heathcote E
- Heer Rs
- Heesakkers H
- Heiloo S
- Heminway R
- Henderson C
- Henderson I
- Henderson La
- Heneghan H
- Hengeveld E
- Henson Ad
- Heppenstall-Harris G
- Herken M
- Hernandez Kakauridze S
- Hernandez Ros Mi
- Hernandez-Lizoáin Jl
- Hernon J
- Herron J
- Heskin J
- Hester E
- Hewitt Cm
- Heywood E
- Heywood Eg
- Hibberd A
- Hickling Sl
- Hidalgo Pujol M
- Hidding E
- Higgins A
- Higgins P
- Higgs L
- Hill A
- Hill F
- Hindle Fisher I
- Hirani S
- Hirst F
- Hitchen N
- Ho S
- Ho W
- Hoban Ka
- Hoffman Rpc
- Hogendoorn W
- Holliday Rbs
- Holloway C
- Holmes C
- Holmes Mjv
- Holton P
- Holyoak H
- Home J
- Horgan Pg
- Horne L
- Horst C
- Horth D
- Hoskins Tc
- Hourston Gjm
- Howard James N
- Howells L
- Hu L
- Huang Hc
- Hudson-Phillips S
- Hughes Ba
- Hughes F
- Hughes Rk
- Hulley K
- Hung G
- Hurný M
- Hurst Pc
- Huseynova S
- Husnoo Sb
- Hussain N
- Hussain O
- Hutchings I
- Huzmeli E
- Ibrahim A
- Ibrahim I
- Ilbak A
- Inci Et
- Ingham R
- Ingram E
- Innocenti P
- Iorga R
- Iqbal A
- Iqbal S
- Isaac A
- Isler Vc
- Iyer S
- Jackson Hr
- Jackson S
- Jacob L
- Jafree Dj
- Jaitley A
- Jalota P
- Jamal N
- Janssen Tl
- Jaroš J
- Jathanna N
- Jawad As
- Jayakody N
- Jenkin Sl
- Jenvey C
- Jewell Pd
- Jeyabraba S
- Jhala H
- Jimenez Escovar F
- Jimenez-Gomez Lm
- Jimenez-Segovia M
- Jiménez-Morillas P
- Jiménez-Viñas C
- Jindal A
- Johnston A
- Johnston J
- Johnstone M
- Jones Cs
- Jong N
- Jordan Hem
- Joshi D
- Joshi Kr
- Joyce Hl
- Joyner C
- Jubainville Cl
- Jull P
- Jurgens J
- Kabariti R
- Kadicheeni M
- Kahar A
- Kakil E
- Kalra N
- Kamarajah Sk
- Kanabar S
- Kane T
- Kankam Hkn
- Kara B
- Kara C
- Kara E
- Karabacak U
- Karabulut E
- Karahan B
- Karia M
- Karia P
- Karsan Rb
- Karunakaran P
- Karásek D
- Kasap S
- Kasar P
- Kaushal A
- Kaya A
- Kayacan S
- Kayaci Durak M
- Kazmi Z
- Keane Cp
- Keane N
- Keane P
- Kee Jy
- Keeling Re
- Keelty N
- Keevil H
- Kelesoglu Y
- Kelly M
- Kelly Me
- Kelly N
- Kennedy Ed
- Kennedy Hr
- Kerai A
- Kerimova N
- Kerin Mj
- Kerr Al
- Keyif Mf
- Khaing Ph
- Khajuria A
- Khalid H
- Khan A
- Khan I
- Khan M
- Khan S
- Khan T
- Khan U
- Khangura J
- Khanijau R
- Khatri C
- Khattak M
- Khetarpal Aa
- Khokhar Ha
- Khonat Z
- Khonsari P
- Kiely A
- Kiff R
- Kilic E
- Kilinc C
- Kim Jw
- Kim S
- Kimani L
- King M
- Kip M
- Kishore A
- Kisyov I
- Kitt H
- Kleine E
- Klinkert M
- Kloppenberg Fwh
- Knight Cl
- Kobal Bb
- Koc Ge
- Kocapinar S
- Kocer Md
- Koksal G
- Koksal S
- Kong C
- Kong Cy
- Konsten J
- Kopac O
- Koppe M
- Kosasih Sr
- Koshy Rm
- Kotecha D
- Koumpa F
- Kow K
- Koysombat K
- Koç F
- Koç M
- Kreibich A
- Kretzmer L
- Kucukdiler E
- Kuiper J
- Kuiper Sz
- Kullac S
- Kumar An
- Kumaran G
- Kurklu O
- Kurt A
- Kuzey A
- Kwan Ml
- Kwang P
- Laguna Román S
- Lakhani M
- Lakhani Sm
- Lakshmipathy G
- Lalor P
- Lamont J
- Langenhoff B
- Lankage Cm
- Lap Cr
- Larotonda C
- Laterza V
- Latras-Cortés I
- Laurino A
- Lavery J
- Lazenby D
- Leafe O
- Ledsam A
- Lee Ahy
- Lee J
- Lee S
- Lees Dm
- Lek C
- Leong S
- Leslie Ke
- Leung W
- Leventoglu S
- Lewis T
- Li Hi Shing S
- Li Mm
- Li N
- Licari L
- Liew W
- Liew Y
- Lim Ae
- Lim D
- Lim E
- Lim J
- Lim K
- Lim S
- Lim Sj
- Linton A
- Liu C
- Liu S
- Livesey A
- Lo Secco G
- Lo T
- Lockey Jw
- Logan Ae
- Loke W
- Long F
- Long K
- Longstaff L
- Loo J
- Looijen Rc
- Lopes S
- Lopez Garcia Mc
- Lopez G
- Lotfallah A
- Lou Cn
- Loughran D
- Loveday J
- Low Jyl
- Lowe R
- Lu Q
- Lua Boon Xuan J
- Lucas de Carvalho J
- Luehrman A
- Luhishi A
- Lujan Mompean Ja
- Luk Cy
- Lunawat S
- Lwin Kn
- Lykoudis Pm
- Lynch As
- Lynne S
- Lyons A
- Lyons R
- López-Mármol R
- López-Vendrell L
- Löwensteyn Yn
- Maamari R
- Maan Ds
- Macaskill A
- Macdonald A
- Macdonald J
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- Mackin S
- Maclennan D
- Magnoli M
- Mah J
- Mahboob S
- Mahesh S
- Maheswaran Y
- Mahmood J
- Majid S
- Major C
- Malaj M
- Malak M
- Malik A
- Mallick S
- Malys Mk
- Manson R
- Mansoor S
- Manvydas V
- Maple N
- Marchal St
- Marchese N
- Marcos Rodrigo A
- Mariani F
- Markham Rm
- Marsden M
- Marsh A
- Marsh L
- Marshall Dc
- Marti Gelonch L
- Martin Morales E
- Martin Al
- Martin R
- Martinez Diaz Jm
- Martinez Rios Ce
- Martorana M
- Martí Fernández Rm
- Martínez Chillarón E
- Maru D
- Mason Jd
- Masood M
- Mastan A
- Mastandrea Bonaviri Gn
- Mate-Mate P
- Matheson J
- Matthams J
- Matthews Bw
- Matthews Jh
- Mauro D
- Maxwell-Armstrong C
- Mayes Jw
- Mazan K
- Mazumdar E
- Mcaleer E
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- Mcallister R
- Mcauley D
- Mcbride A
- Mccabe G
- Mccance E
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- Mcclymont Lf
- Mccormack Dr
- Mccrann C
- Mcdowell M
- Mcenhill Pm
- Mcfarlane H
- Mcgalliard Rj
- Mcgarrigle C
- Mcgarvie S
- Mcgenity C
- Mcgowan C
- Mcgrath A
- Mcgregor Rj
- Mcintyre Cj
- Mckean E
- Mckelvey Ll
- Mckerr Cn
- Mckevitt Kl
- Mclaughin C
- Mclean Rc
- Mclure Sw
- Mcmenamin M
- Mcmullan R
- Mcnamee L
- Mcrobbie Hd
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- Meek J
- Mehdi A
- Mehta Jk
- Meijerink Wjhj
- Menduni N
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- Mensink G
- Mericliler M
- Mermer S
- Messina F
- Mestres Petit N
- Metcalf P
- Mian A
- Milana F
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- Milne S
- Minhas M
- Mirallas Viñas O
- Miranda Bh
- Mirdavoudi V
- Mirza M
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- Mistry Bd
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- Mitchell H
- Mitha N
- Mithrakumar P
- Mitrasinovic S
- Mittapalli D
- Mitxelena Elosegi L
- Mizan Sr
- Mogan Yp
- Mohamed Us
- Mohamud M
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- Momoh Z
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- Monzonis Hernandez X
- Moody N
- Moon Rdc
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- Moran D
- Morandi V
- Moratilla Lapeña L
- Morgan C
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- Morley R
- Moroni P
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- Morrison P
- Mortimer A
- Morton D
- Mosterd Cm
- Mugurtay Ys
- Mulder Im
- Muller S
- Mural-Krishnan S
- Muriel P
- Murkin C
- Muro M
- Murphy L
- Murray Se
- Murtaza A
- Murtaza Mi
- Mushtaq J
- Mustafa S
- Musters Gd
- Mutlu B
- Mutlu D
- Myers L
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- Naccari Pm
- Nachiappan R
- Nadanakumaran K
- Naqib S
- Narain A
- Naran P
- Narang Y
- Narayan P
- Narramore R
- Narwani V
- Navayogaarajah V
- Naveed H
- Nayee H
- Neary A
- Nehikhare I
- Nelaj S
- Nelli T
- Neo Yn
- Neophytou C
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- Nesargikar Pn
- Ng Ayl
- Ng Gs
- Ng Jck
- Ng Jq
- Ng K
- Ng L
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- Ngaage M
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- Nixon G
- Noone Tm
- Norris Jm
- North As
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- Nota Clma
- Notarnicola M
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- O'Byrne L
- O'Carroll O
- O'Connell C
- O'Connor A
- O'Connor S
- O'Dwyer M
- O'Flynn Ld
- O'Kane A
- O'Loughlin Ra
- O'Neill Em
- O'Neill S
- O'Reilly D
- O'Sullivan Da
- O'Sullivan H
- O'Sullivan K
- Oakley T
- Obute Rd
- Odeleye A
- Ogunleye O
- Olivier J
- Omar A
- Omara S
- Omer Hm
- Onar D
- Oncel M
- Ong Kk
- Onsal U
- Oostendorp Se
- Oremule B
- Orhalmi J
- Orhan K
- Osei-Kuffour D
- Osman S
- Oudman Ts
- Oun H
- Owasil R
- Owczarek S
- Ozbalci Gs
- Ozben V
- Ozgencil B
- Ozmen Bb
- Ozsipahi Ac
- Padilla Valverde D
- Paine Hr
- Pal S
- Palanivail N
- Palkhi E
- Pallara E
- Palmer C
- Palmieri A
- Palmisano S
- Palos Campos Mc
- Palyzová H
- Pandey A
- Pandey G
- Pando Ruiz B
- Pang G
- Pantalone Mr
- Paolo G
- Papandrea M
- Papazachariou Sk
- Parajo A
- Paraoan V
- Parimli H
- Parinisi Z
- Park Jh
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- Parkin J
- Parmar E
- Parsons S
- Parthiban S
- Pasquali S
- Pasqualoni M
- Pastor-Riquelme P
- Pata F
- Patel B
- Patel Ba
- Patel By
- Patel Jb
- Patel K
- Patel M
- Patel N
- Patel P
- Patel S
- Patel T
- Patel V
- Pattapola V
- Patturelli M
- Paul J
- Pearce J
- Pearse Rj
- Peck Fs
- Pehlivan M
- Peinado Iribar B
- Pektas Am
- Pellino G
- Perera M
- Perez Arias H
- Perez Costoya C
- Perez Febles M
- Perez Jl
- Perez-Gandara B
- Pericleous A
- Peroos S
- Perrotta G
- Persiani R
- Pesser N
- Peters M
- Petra H
- Petrarca M
- Petrov G
- Pezas Tp
- Pezzuto R
- Phan Pn
- Phillips C
- Picciariello A
- Pickard J
- Pietrabissa A
- Pike G
- Pineño-Flores C
- Pinkney Td
- Pinto R
- Piquet A
- Piraliyev E
- Piran G
- Pistola I
- Pitts-Tucker T
- Pizzolato A
- Pla Seró S
- Player C
- Plomer-Sanchez M
- Poacher A
- Poelman M
- Polat F
- Polat Zp
- Ponweera A
- Poo Sx
- Pope S
- Portugal Porras V
- Posada M
- Posteki G
- Poyato Nuñez Fj
- Prabhudesai A
- Prado Perez R
- Prakash E
- Preece R
- Prest-Smith J
- Priani P
- Priestland R
- Prieto-Nieto Mi
- Pronk A
- Protti Ruiz Gp
- Prys-Jones O
- Ptacek Ib
- Puan L
- Puccioni C
- Pujol-Cano N
- Pulpito S
- Punj R
- Punjabi N
- Pös M
- Qamar Ma
- Quill S
- Quinn K
- Qureshi A
- Qureshi S
- Qureshi U
- Rabinthiran S
- Radotra A
- Rafiq Nm
- Raghuvir V
- Raghvani T
- Rahmee Cns
- Raimondi P
- Raina V
- Rajan N
- Raji K
- Rakhimov I
- Raman Kp
- Ramana A
- Ramjeeawon N
- Ramnarine A
- Rampal R
- Rampulla V
- Ramsay N
- Ramtoola T
- Randisi B
- Rangan T
- Rangedara A
- Raphael M
- Rashid M
- Rashid S
- Rasiah Mg
- Ratnakumaran R
- Rattan G
- Ratu Sg
- Raurich-Leandro J
- Raut P
- Reakes T
- Realis Luc A
- Redgrave Na
- Redmond A
- Reed A
- Reeder C
- Reehal Rs
- Rees C
- Rees S
- Reeves T
- Reggiani L
- Reid Kg
- Reid Nb
- Reid R
- Rejayee M
- Remedios J
- Remore Lm
- Reynolds J
- Rhema Ia
- Ribbink Me
- Ridgway P
- Rinkoff S
- Ripa M
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- Riva M
- Rizzi A
- Rob T
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- Roberts Hf
- Robertson Dt
- Robertson Kl
- Robertson V
- Robinson C
- Robinson M
- Robson J
- Rocco I
- Roche D
- Rocke As
- Rodrigues Silva K
- Rodriguez Garcia R
- Rogers Je
- Rogers S
- Rojoa D
- Romano F
- Romeo F
- Romero-Simó M
- Rookes Cw
- Roquet Puigneró E
- Rosati G
- Rosati R
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- Ross H
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- Rossi E
- Rothwell L
- Roura J
- Roy Csd
- Rubbini M
- Rubio-Perez I
- Ruiz Montesinos I
- Ruiz Em
- Russell G
- Ryan M
- Saat Mi
- Sabine Lm
- Sacco R
- Sagar R
- Saglam Za
- Sagmeister M
- Sahathevan A
- Sahin A
- Sait Ms
- Sajjad U
- Sakman G
- Salam Gj
- Salamone G
- Salazar-García C
- Sale T
- Salem M
- Salih Ae
- Salman M
- Salmon D
- Sam Zh
- Sammarco G
- Sampietro G
- San Martín Bragado M
- Sanchez Cambronero M
- Sanchez A
- Sanchez-Guillen L
- Sanders Ja
- Sandhu Kk
- Sandhu S
- Sandison L
- Sangal P
- Santocchi P
- Sanz Ortega G
- Sapci I
- Saraceno F
- Sari V
- Sartori A
- Sarvanandan T
- Sarwar S
- Sasapu K
- Satterthwaite L
- Schasfoort Ra
- Schiphorst A
- Schizas A
- Schmidt Pa
- Schofield E
- Schok T
- Schulz Tm
- Schulzová M
- Scotcher Se
- Seager E
- Sebaoui S
- Secilmis E
- Sedee Wja
- Seedat M
- Segall E
- Segura-Sampedro Jj
- Sellathurai J
- Selvachandran H
- Selvaggi F
- Selvaggi L
- Semana Ad
- Semiz A
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- Semple E
- Sen Ay
- Sena-Ruiz F
- Senay Bb
- Seneviratne N
- Sengul N
- Sensi B
- Senturk E
- Sethi Rk
- Sette M
- Seyhan U
- Seyrek N
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- Sgrò A
- Shafi Ama
- Shafiq Nm
- Shah A
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- Shah R
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- Shahid S
- Shahidi S
- Shakweh E
- Shamsul Badrin Ak
- Shanahan D
- Sharifpour M
- Sharma Khatiwada A
- Shatkar V
- Shaunak R
- Sheikh Imi
- Sheldon A
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- Sherif Ma
- Sherliker Gxj
- Sheth S
- Shoa M
- Shufflebotham H
- Shuker Ba
- Shukla A
- Shumon S
- Shurovi B
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- Shuttleworth Rh
- Sica G
- Siddiqui M
- Siddiqui Zh
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- Simon Frapolli V
- Simpson A
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- Singh B
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- Sinha A
- Sinha Y
- Sirakaya M
- Sitta O
- Sivrikaya T
- Skalamera I
- Slade R
- Slieker Fjb
- Smart Nj
- Smeets Hj
- Smet M
- Smith Acd
- Smith Ag
- Smith Dne
- Smith N
- Smolák P
- Sng S
- Soldevila-Verdeguer C
- Soo Yh
- Soon Wc
- Sorah T
- Soria Aledo V
- Sotona O
- Soylemez Zobb
- Sozuer Em
- Spence O
- Spencer T
- Spijkerman R
- Springford Lr
- Sproule L
- Sreh A
- Srikantharajah M
- Sritharan P
- Staderini F
- Stanger Sa
- Stanley Gh
- Stanley S
- Stassen Lps
- Stather Pw
- Steccanella F
- Stechman M
- Steel M
- Stein J
- Stellingwerf Me
- Steup Wh
- Stevens S
- Stewart Ge
- Stezaker S
- Stijns Rch
- Stoddart Mt
- Stokes S
- Stone Ej
- Stott Gd
- Strange E
- Street An
- Subasi A
- Sukkari M
- Sukumar S
- Suleman Yn
- Sullivan Jal
- Sun E
- Sundar-Singh M
- Suppa A
- Suresh Rs
- Suresh S
- Syeed Ja
- Sykes Mc
- Szczap A
- Sánchez Estébanez E
- Sánchez-Blasco L
- Tagariello F
- Tahir M
- Tahmina A
- Tai A
- Talukdar Ss
- Tan D
- Tan Esm
- Tan Et
- Tan R
- Tan S
- Tan Y
- Tan Yh
- Tansoker I
- Tarantino M
- Targa S
- Taskin O
- Taskin Rb
- Tavuz Ai
- Tay Ay
- Tayeh S
- Taylor F
- Taşçı Y
- Tear Ak
- Teh Jw
- Teixeira da Silva M
- Tejero Pintor Fj
- Telfer R
- Temiz C
- Teng V
- Teoh Pj
- Ter Bruggen Ffja
- Ter Horst L
- Ter Weele K
- Thacoor A
- Thakker Ce
- Thakur H
- Tharakan Rg
- Tharmachandirar T
- Theodoreson Md
- Theodoropoulou K
- Thethi R
- Thevathasan Aa
- Thirumal V
- Thomas D
- Thomas G
- Thomas-Davies M
- Thompson Jd
- Thompson Od
- Tiedt L
- Tilston Tw
- Tippins F
- Tirnaksiz Mb
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- Tognolo L
- Toh C
- Tomas K
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- Tongo F
- Tonkins M
- Toorenvliet Br
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- Topham C
- Torlot Ge
- Torrance Hd
- Tosun V
- Toto Of
- Trail M
- Traynor Bp
- Trecarten S
- Trimble A
- Trist Aj
- Troia A
- Trompetto M
- Truma A
- Truss A
- Tsui Ay
- Tulum H
- Tung L
- Turaga S
- Turati L
- Turkmen M
- Turley H
- Turnbull Ja
- Turner Ejh
- Turner J
- Turner L
- Turner M
- Turpan M
- Tutam Dn
- Ucar E
- Uctepe F
- Uittenbogaart M
- Ulkucu A
- Ulusahin M
- Unal Ag
- Ungcharoen N
- Uppal E
- Urquhart A
- Uzun B
- Uzun O
- Uzun S
- Uzunoglu Ec
- Vable T
- Valderrama Pérez A
- Valli A
- Vallve-Bernal M
- Van Bruggen D
- van Dalen Ashm
- van de Ven Awh
- van der Harst E
- van der Hoeven Ac
- Van der Lubbe M
- van der Pool Aem
- van der Zee C
- Van Dijck Wpm
- van Elst Tr
- van Engelenburg T
- van Geloven A
- Van Grevenstein Wmu
- Van Heumen Tm
- van Leeuwen Bl
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- van Steensel L
- Van Tol Rr
- van Verschuer Vmt
- van Wijnbergen Jwm
- Vanmali P
- Varley R
- Varma D
- Varma N
- Varma Rk
- Varo Muñoz A
- Vasko P
- Vasquez G
- Vaughan R
- Vazquez-Gonzalez I
- Veenker Cgh
- Vela Polanco Ff
- Vendramin E
- Venn M
- Ventre Cm
- Venturini S
- Verardi L
- Verboeket B
- Verma K
- Verma S
- Vermaas M
- Vernon Ok
- Villarejo Campos P
- Vinci A
- Vithanage Na
- Vivekanantham S
- Vives-Rodriguez E
- Viñas-Salas J
- Vries Jjm
- Wadanamby S
- Waldron Rm
- Walford Ra
- Wali A
- Wall C
- Walsh Sl
- Wan Jc
- Wang A
- Wang S
- Ward Ae
- Ward N
- Ward T
- Warren N
- Warwick Hl
- Watson N
- Watson Rp
- Weaver R
- Webb E
- Weinberg D
- Wells M
- Weston C
- Wetherall N
- Whacha C
- Whatling Ea
- Whewell H
- White A
- White Cj
- White U
- Whitehurst K
- Whitham Rdj
- Whittingham H
- Wiersema R
- Wiezer R
- Wijesekera M
- Wijffels N
- Wijnhoven Bpl
- Wild Jrl
- Wilkinson D
- Willems L
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- Williams M
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- Williams P
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- Wills J
- Wilson H
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- Wilson R
- Wilson T
- Wiltshire Jj
- Winarski A
- Wing Vc
- Wingfield Lr
- Winslow F
- Woin E
- Wong C
- Wong E
- Wong V
- Wood Ad
- Woodcock N
- Woodward H
- Woon E
- Wright A
- Wright Ev
- Wye J
- Wylam D
- Wylie J
- Wynell-Mayow Wm
- Xiao C
- Xu Gx
- Xylas D
- Yalcin Y
- Yaman S
- Yan A
- Yang T
- Yasar C
- Yates Ja
- Yauw S
- Yavuz G
- Yazkan Z
- Yekenkurul E
- Yener A
- Yeoh Tsl
- Yetiskin E
- Yıgman S
- Yildirim N
- Yildirim R
- Yildiz S
- Yildiz Ss
- Yildiz T
- Yilmaz I
- Yilmaz M
- Yilmaz S
- Yilmaz T
- Yim N
- Yoganathan S
- Yong Cs
- Yong N
- Yoruk I
- Yousif A
- Yow L
- Yuen R
- Yuksek B
- Yuksek Ma
- Yuksel A
- Yurdaor Ss
- Yurekli Am
- Zaidi R
- Zegeye Mi
- Zengin T
- Zhang Aa
- Zhao J
- Ziff O
- Zigiotto D
- Zijlmans Jl
- Zimmerman D
- Ziprin P
- Zope S
- Zuhair M
- Örhalmi J
- Özkan Bb
- Šimáčková B
- Široká M
- Žebrák R
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2018
- Field of study
Aim Previous studies reported conflicting evidence on the effects of obesity on outcomes after gastrointestinal surgery. The aims of this study were to explore the relationship of obesity with major postoperative complications in an international cohort and to present a metaanalysis of all available prospective data. Methods This prospective, multicentre study included adults undergoing both elective and emergency gastrointestinal resection, reversal of stoma or formation of stoma. The primary end-point was 30-day major complications (Clavien\u2013Dindo Grades III\u2013V). A systematic search was undertaken for studies assessing the relationship between obesity and major complications after gastrointestinal surgery. Individual patient meta-analysis was used to analyse pooled results. Results This study included 2519 patients across 127 centres, of whom 560 (22.2%) were obese. Unadjusted major complication rates were lower in obese vs normal weight patients (13.0% vs 16.2%, respectively), but this did not reach statistical significance (P = 0.863) on multivariate analysis for patients having surgery for either malignant or benign conditions. Individual patient meta-analysis demonstrated that obese patients undergoing surgery formalignancy were at increased risk of major complications (OR 2.10, 95% CI 1.49\u20132.96, P < 0.001), whereas obese patients undergoing surgery for benign indications were at decreased risk (OR 0.59, 95% CI 0.46\u20130.75, P < 0.001) compared to normal weight patients. Conclusions In our international data, obesity was not found to be associated with major complications following gastrointestinal surgery. Meta-analysis of available prospective data made a novel finding of obesity being associated with different outcomes depending on whether patients were undergoing surgery for benign or malignant disease
Body mass index and complications following major gastrointestinal surgery: a prospective, international cohort study and meta-analysis.
- Author
- 6rhalmi J
- 6zkan Bb
- \u160im\ue1\u10dkov\ue1 B
- \u160irok\ue1 M
- \u17debr\ue1k R
- Aarts E
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- Abdelgalil R
- Abdelhadi M
- Abdikadir Hr
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- Sorah T
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- Sun E
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- Suppa A
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- Tahmina A
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- Van der Lubbe M
- van der Pool Aem
- van der Zee C
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- Van Grevenstein Wmu
- Van Heumen Tm
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- van Rijckevorsel Vajim
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- van Wijnbergen Jwm
- Vanmali P
- Varley R
- Varma D
- Varma N
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- Vasko P
- Vasquez G
- Vaughan R
- Vazquez-Gonzalez I
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- Woodcock N
- Woodward H
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- Wright Ev
- Wye J
- Wylam D
- Wylie J
- Wynell-Mayow Wm
- Xiao C
- Xu Gx
- Xylas D
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- Yalcin Y
- Yaman S
- Yan A
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- Yasar C
- Yates Ja
- Yauw S
- Yavuz G
- Yazkan Z
- Yekenkurul E
- Yener A
- Yeoh Tsl
- Yetiskin E
- Yildirim N
- Yildirim R
- Yildiz S
- Yildiz Ss
- Yildiz T
- Yilmaz I
- Yilmaz M
- Yilmaz S
- Yilmaz T
- Yim N
- Yoganathan S
- Yong Cs
- Yong N
- Yoruk I
- Yousif A
- Yow L
- Yuen R
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- Yuksek Ma
- Yuksel A
- Yurdaor Ss
- Yurekli Am
- Zaidi R
- Zegeye Mi
- Zengin T
- Zhang Aa
- Zhao J
- Ziff O
- Zigiotto D
- Zijlmans Jl
- Zimmerman D
- Ziprin P
- Zope S
- Zuhair M
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2018
- Field of study
AIM:
Previous studies reported conflicting evidence on the effects of obesity on outcomes after gastrointestinal surgery. The aims of this study were to explore the relationship of obesity with major postoperative complications in an international cohort and to present a meta-analysis of all available prospective data.
METHODS:
This prospective, multicentre study included adults undergoing both elective and emergency gastrointestinal resection, reversal of stoma or formation of stoma. The primary end-point was 30-day major complications (Clavien-Dindo Grades III-V). A systematic search was undertaken for studies assessing the relationship between obesity and major complications after gastrointestinal surgery. Individual patient meta-analysis was used to analyse pooled results.
RESULTS:
This study included 2519 patients across 127 centres, of whom 560 (22.2%) were obese. Unadjusted major complication rates were lower in obese vs normal weight patients (13.0% vs 16.2%, respectively), but this did not reach statistical significance (P = 0.863) on multivariate analysis for patients having surgery for either malignant or benign conditions. Individual patient meta-analysis demonstrated that obese patients undergoing surgery for malignancy were at increased risk of major complications (OR 2.10, 95% CI 1.49-2.96, P < 0.001), whereas obese patients undergoing surgery for benign indications were at decreased risk (OR 0.59, 95% CI 0.46-0.75, P < 0.001) compared to normal weight patients.
CONCLUSIONS:
In our international data, obesity was not found to be associated with major complications following gastrointestinal surgery. Meta-analysis of available prospective data made a novel finding of obesity being associated with different outcomes depending on whether patients were undergoing surgery for benign or malignant disease
Global, regional, and national age-sex-specific mortality and life expectancy, 1950–2017: a systematic analysis for the Global Burden of Disease Study 2017
- Author
- Abate D
- Abate KH
- Abay SM
- Abbafati C
- Abbasi N
- Abbastabar H
- Abd-Allah F
- Abdel-Rahman O
- Abdela J
- Abdelalim A
- Abdi A
- Abdollahpour I
- Abdulkader RS
- Abdurahman AA
- Abebe HT
- Abebe M
- Abebe Z
- Abebo TA
- Aboyans V
- Abraha HN
- Abrham AR
- Abu-Raddad LJ
- Abu-Rmeileh NME
- Accrombessi MMK
- Acharya P
- Adebayo OM
- Adedeji IA
- Adedoyin RA
- Adekanmbi V
- Adetokunboh OO
- Adhena BM
- Adhikari TB
- Adib MG
- Adou AK
- Adsuar JC
- Afarideh M
- Afshin A
- Agarwal G
- Aggarwal R
- Aghayan SA
- Agrawal A
- Agrawal S
- Ahmadi A
- Ahmadi M
- Ahmadieh H
- Ahmed MB
- Ahmed MLCB
- Ahmed S
- Aichour AN
- Aichour I
- Aichour MTE
- Akanda AS
- Akbari ME
- Akibu M
- Akinyemi RO
- Akinyemiju T
- Akseer N
- Al-Aly Z
- Al-Eyadhy A
- Al-Raddadi RM
- Alahdab F
- Alam K
- Alebel A
- Aleman AV
- Alene KA
- Ali R
- Alijanzadeh M
- Alizadeh-Navaei R
- Aljunid SM
- Alkerwi A
- Alla F
- Allebeck P
- Allen CA
- Alonso J
- Alsharif U
- Altirkawi K
- Alvis-Guzman N
- Amare AT
- Amini E
- Ammar W
- Amoako YA
- Anber NH
- Andrei CL
- Androudi S
- Animut MD
- Anjomshoa M
- Anlay DZ
- Ansari H
- Ansariadi A
- Ansha MG
- Antonio CAT
- Appiah SCY
- Aremu O
- Areri HA
- Arora M
- Artaman A
- Aryal KK
- Asadi-Lari M
- Asayesh H
- Asfaw ET
- Asgedom SW
- Assadi R
- Ataro Z
- Atey TMM
- Athari SS
- Atique S
- Atre SR
- Atteraya MS
- Attia EF
- Ausloos M
- Avila-Burgos L
- Avokpaho EFGA
- Awasthi A
- Awuah B
- Ayala Quintanilla BP
- Ayele HT
- Ayele Y
- Ayer R
- Ayuk TB
- Azzopardi PS
- Azzopardi-Muscat N
- Badali H
- Badawi A
- Balakrishnan K
- Bali AG
- Banach M
- Banstola A
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- Ärnlöv J
- Çavlin A
- Øverland S
- Publication venue
- 'Elsevier BV'
- Publication date
- 01/01/2018
- Field of study
Background Assessments of age-specific mortality and life expectancy have been done by the UN Population Division, Department of Economics and Social Affairs (UNPOP), the United States Census Bureau, WHO, and as part of previous iterations of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD). Previous iterations of the GBD used population estimates from UNPOP, which were not derived in a way that was internally consistent with the estimates of the numbers of deaths in the GBD. The present iteration of the GBD, GBD 2017, improves on previous assessments and provides timely estimates of the mortality experience of populations globally. Methods The GBD uses all available data to produce estimates of mortality rates between 1950 and 2017 for 23 age groups, both sexes, and 918 locations, including 195 countries and territories and subnational locations for 16 countries. Data used include vital registration systems, sample registration systems, household surveys (complete birth histories, summary birth histories, sibling histories), censuses (summary birth histories, household deaths), and Demographic Surveillance Sites. In total, this analysis used 8259 data sources. Estimates of the probability of death between birth and the age of 5 years and between ages 15 and 60 years are generated and then input into a model life table system to produce complete life tables for all locations and years. Fatal discontinuities and mortality due to HIV/AIDS are analysed separately and then incorporated into the estimation. We analyse the relationship between age-specific mortality and development status using the Socio-demographic Index, a composite measure based on fertility under the age of 25 years, education, and income. There are four main methodological improvements in GBD 2017 compared with GBD 2016: 622 additional data sources have been incorporated; new estimates of population, generated by the GBD study, are used; statistical methods used in different components of the analysis have been further standardised and improved; and the analysis has been extended backwards in time by two decades to start in 1950. Findings Globally, 18·7% (95% uncertainty interval 18·4–19·0) of deaths were registered in 1950 and that proportion has been steadily increasing since, with 58·8% (58·2–59·3) of all deaths being registered in 2015. At the global level, between 1950 and 2017, life expectancy increased from 48·1 years (46·5–49·6) to 70·5 years (70·1–70·8) for men and from 52·9 years (51·7–54·0) to 75·6 years (75·3–75·9) for women. Despite this overall progress, there remains substantial variation in life expectancy at birth in 2017, which ranges from 49·1 years (46·5–51·7) for men in the Central African Republic to 87·6 years (86·9–88·1) among women in Singapore. The greatest progress across age groups was for children younger than 5 years; under-5 mortality dropped from 216·0 deaths (196·3–238·1) per 1000 livebirths in 1950 to 38·9 deaths (35·6–42·83) per 1000 livebirths in 2017, with huge reductions across countries. Nevertheless, there were still 5·4 million (5·2–5·6) deaths among children younger than 5 years in the world in 2017. Progress has been less pronounced and more variable for adults, especially for adult males, who had stagnant or increasing mortality rates in several countries. The gap between male and female life expectancy between 1950 and 2017, while relatively stable at the global level, shows distinctive patterns across super-regions and has consistently been the largest in central Europe, eastern Europe, and central Asia, and smallest in south Asia. Performance was also variable across countries and time in observed mortality rates compared with those expected on the basis of development. Interpretation This analysis of age-sex-specific mortality shows that there are remarkably complex patterns in population mortality across countries. The findings of this study highlight global successes, such as the large decline in under-5 mortality, which reflects significant local, national, and global commitment and investment over several decades. However, they also bring attention to mortality patterns that are a cause for concern, particularly among adult men and, to a lesser extent, women, whose mortality rates have stagnated in many countries over the time period of this study, and in some cases are increasing
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
- Author
- Abdelmohsen K
- Abe A
- Abedin MJ
- Abeliovich H
- Acevedo Arozena A
- Adachi H
- Adams CM
- Adams PD
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