87,065 research outputs found

    A dc-coupled noninverting one-shot Patent

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    Transistorized dc-coupled multivibrator with noninverted output signa

    Efficient Contact State Graph Generation for Assembly Applications

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    An important aspect in the design of many automated assembly strategies is the ability to automatically generate the set of contact states that may occur during an assembly task. In this paper, we present an efficient means of constructing the set of all geometrically feasible contact states that may occur within a bounded set of misalignments (bounds determined by robot inaccuracy). This set is stored as a graph, referred to as an Assembly Contact State Graph (ACSG), which indicates neighbor relationships between feasible states. An ACSG is constructed without user intervention in two stages. In the first stage, all hypothetical primitive principle contacts (PPCs; all contact states allowing 5 degrees of freedom) are evaluated for geometric feasibility with respect to part-imposed and robot-imposed restrictions on relative positioning (evaluated using optimization). In the second stage, the feasibility of each of the various combinations of PPCs is efficiently evaluated, first using topological existence and uniqueness criteria, then using part-imposed and robot-imposed geometric criteria

    Clerocidin selectively modifies the gyrase-DNA gate to induce irreversible and reversible DNA damage

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    Clerocidin (CL), a microbial diterpenoid, reacts with DNA via its epoxide group and stimulates DNA cleavage by type II DNA topoisomerases. The molecular basis of CL action is poorly understood. We establish by genetic means that CL targets DNA gyrase in the gram-positive bacterium Streptococcus pneumoniae, and promotes gyrase-dependent single- and double-stranded DNA cleavage in vitro. CL-stimulated DNA breakage exhibited a strong preference for guanine preceding the scission site (-1 position). Mutagenesis of -1 guanines to A, C or T abrogated CL cleavage at a strong pBR322 site. Surprisingly, for double-strand breaks, scission on one strand consistently involved a modified (piperidine-labile) guanine and was not reversed by heat, salt or EDTA, whereas complementary strand scission occurred at a piperidine-stable -1 nt and was reversed by EDTA. CL did not induce cleavage by a mutant gyrase (GyrA G79A) identified here in CL-resistant pneumococci. Indeed, mutations at G79 and at the neighbouring S81 residue in the GyrA breakage-reunion domain discriminated poisoning by CL from that of antibacterial quinolones. The results suggest a novel mechanism of enzyme inhibition in which the -1 nt at the gyrase-DNA gate exhibit different CL reactivities to produce both irreversible and reversible DNA damage

    Robust Procedures for Obtaining Assembly Contact State Extremal Configurations

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    Two important components in the selection of an admittance that facilitates force-guided assembly are the identification of: 1) the set of feasible contact states, and 2) the set of configurations that span each contact state, i.e., the extremal configurations. We present a procedure to automatically generate both sets from CAD models of the assembly parts. In the procedure, all possible combinations of principle contacts are considered when generating hypothesized contact states. The feasibility of each is then evaluated in a genetic algorithm based optimization procedure. The maximum and minimum value of each of the 6 configuration variables spanning each contact state are obtained by again using genetic algorithms. Together, the genetic algorithm approach, the hierarchical data structure containing the states, the relationships among the states, and the extremals within each state are used to provide a reliable means of identifying all feasible contact states and their associated extremal configurations

    Evaluating Digital Math Tools in the Field

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    Many school districts have adopted digital tools to supplement or replace teacher-led instruction, usually based on the premise that these tools can provide more personalized or individualized experiences for students and at lower cost. Rigorously evaluating whether such initiatives promote better student outcomes in the field is difficult as most schools and teachers are unwilling to enforce rigorous study designs such as randomized control trials. We used study designs that were feasible in practice to assess whether two digital math tools, eSpark and IXL, were associated with improvements in 3rd – 6th grade student test scores in math. We also investigated the resource requirements and costs of implementing eSpark and IXL to assess whether these tools represent a valuable use of resources. We find that while IXL is substantially less costly to implement than eSpark, its use is not significantly associated with students’ math performance

    Central limit theorem for signal-to-interference ratio of reduced rank linear receiver

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    Let sk=1N(v1k,...,vNk)T,\mathbf{s}_k=\frac{1}{\sqrt{N}}(v_{1k},...,v_{Nk})^T, with {vik,i,k=1,...}\{v_{ik},i,k=1,...\} independent and identically distributed complex random variables. Write Sk=(s1,...,sk1,sk+1,...,sK),\mathbf{S}_k=(\mathbf{s}_1,...,\mathbf {s}_{k-1},\mathbf{s}_{k+1},... ,\mathbf{s}_K), Pk=diag(p1,...,pk1,pk+1,...,pK)\mathbf{P}_k=\operatorname {diag}(p_1,...,p_{k-1},p_{k+1},...,p_K), Rk=(SkPkSk+σ2I)\mathbf{R}_k=(\mathbf{S}_k\mathbf{P}_k\mathbf{S}_k^*+\sigma ^2\mathbf{I}) and Akm=[sk,Rksk,...,Rkm1sk]\mathbf{A}_{km}=[\mathbf{s}_k,\mathbf{R}_k\mathbf{s}_k,... ,\mathbf{R}_k^{m-1}\mathbf{s}_k]. Define $\beta_{km}=p_k\mathbf{s}_k^*\mathbf{A}_{km}(\mathbf {A}_{km}^*\times\ mathbf{R}_k\mathbf{A}_{km})^{-1}\mathbf{A}_{km}^*\mathbf{s}_k,referredtoasthesignaltointerferenceratio(SIR)ofuser, referred to as the signal-to-interference ratio (SIR) of user kunderthemultistageWiener(MSW)receiverinawirelesscommunicationsystem.ItisprovedthattheoutputSIRundertheMSWandthemutualinformationstatisticunderthematchedfilter(MF)arebothasymptoticGaussianwhen under the multistage Wiener (MSW) receiver in a wireless communication system. It is proved that the output SIR under the MSW and the mutual information statistic under the matched filter (MF) are both asymptotic Gaussian when N/K\to c>0$. Moreover, we provide a central limit theorem for linear spectral statistics of eigenvalues and eigenvectors of sample covariance matrices, which is a supplement of Theorem 2 in Bai, Miao and Pan [Ann. Probab. 35 (2007) 1532--1572]. And we also improve Theorem 1.1 in Bai and Silverstein [Ann. Probab. 32 (2004) 553--605].Comment: Published in at http://dx.doi.org/10.1214/07-AAP477 the Annals of Applied Probability (http://www.imstat.org/aap/) by the Institute of Mathematical Statistics (http://www.imstat.org

    Neutrino and anti-neutrino transport in accretion disks

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    We numerically solve the one dimensional Boltzmann equation of the neutrino and anti-neutrino transport in accretion disks and obtain the fully energy dependent and direction dependent neutrino and anti-neutrino emitting spectra, under condition that the distribution of the mass density,temperature and chemical components are given. Then, we apply the resulting neutrino and anti-neutrino emitting spectra to calculate the corresponding annihilation rate of neutrino pairs above the neutrino dominated accretion disk and find that the released energy resulting from the annihilation of neutrino pairs can not provide sufficient energy for the most energetic short gamma ray bursts whose isotropic luminosity can be as high as 105210^{52} ergs/s unless the high temperature zone where the temperature is beyond 10 MeV can stretch over 200 km in the disk. We also compare the resulting luminosity of neutrinos and anti-neutrinos with the results from the two commonly used approximate treatment of the neutrino and anti-neutrino luminosity: the Fermi-Dirac black body limit and a simplified model of neutrino transport, i.e., the gray body model, and find that both of them overestimate the neutrino/anti-neutrino luminosity and their annihilation rate greatly. Additionally, as did in Sawyer (2003), we also check the validity of the two stream approximation, and find that it is a good approximation to high accuracy.Comment: Phys. Rev. D in press, 15 preprint papers, 5 figure

    Electrical characteristics of amorphous iron-tungsten contacts on silicon

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    The electrical characteristics of amorphous Fe-W contacts have been determined on both p-type and n-type silicon. The amorphous films were obtained by cosputtering from a composite target. Contact resistivities, pc=1×10^−7 and pc=2.8×10^−6, were measured on n+ and p+ silicon, respectively. These values remain constant after thermal treatment up to at least 500°C. A barrier height, φBn=0.61 V, was measured on n-type silicon
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