Reducing Sound Levels of Granulator at ORBIS Corporation

The plastic granulation process at OrbisCorporation produces noise levels up to 114 decibels. The current noise level at the closest operator station from the grinder is 90 dB.Due to OSHA regulations, noise levels must be decreased to at or below 85 decibels at the nearest operator station

Reducing Sound Levels of Granulator at ORBIS Corporation

ORBIS Corporation, owned by Menasha Corporation, is a manufacturer of reusable plastic bulk containers, hand-held containers, pallets, dunnage and packaging. One of ORBIS’ main goals is to create a sustainable way to improve product flow throughout a supply chain. The ORBIS Corporation, a subsidiary of Menasha Corporation, has more than 35 world-wide locations to improve supply chains in many industries. Some of ORBIS’ customers are companies in the food, beverage, automotive, general manufacturing and pharmaceutical industries. In 2007, ORBIS acquired a major manufacturer of bulk containers, making it North America’s leader in reusable plastic packaging (ORBIS, 2017). ORBIS uses injection molding for their plastic products (Boffeli et al., 2017). The Monticello plant alone has 140 employees, the stakeholders, and produces over 30 million pounds of plastic annually (Wortman, 2017). ORBIS is wants to do whatever it can to reduce the risk to its employees. ORBIS uses a granulator for one of its processes to grind down scrap product to reuse. When an operator runs the granulator, it generates a high decibel level of approximately 114 dB, at the location of the operator. The sound level at the nearest workstation, which is 40 ft. away, is at 91 dB. These levels are significantly higher than OSHA’s standards. The human pain threshold is 120 dB, so this problem could lead to hearing loss, rapid employee turnover, workman’s compensation, and fines from OSHA. ORBIS wants to reduce them to make the work environment safer and more comfortable for employees, and to meet OSHA’s standards. Machines in factories are typically loud, and other companies want to keep the sound levels low just like ORBIS does. We expect that our proposed solution would be applicable to similar situations, especially if it is being applied to a granulator. There are many manufacturers of products, such as sound blankets, that are meant to reduce sound levels in factories, so there are many other companies that have a similar problem that our solution could be applied to

Senior Recital: Christian Fabrizio Artieda, jazz guitar

This recital is presented in partial fulfillment of requirements for the degree Bachelor of Music in Music Education. Mr. Artieda studies jazz guitar with Trey Wright.https://digitalcommons.kennesaw.edu/musicprograms/1137/thumbnail.jp

Devotions for Advent 2022 Canticles of Luke

Each week of this Advent devotional will focus on one of the four Lukan canticles, putting it in its context as well as making connections to other portions of Scripture. At the end of this Advent season, may we, like those who have gone before us, “sing to the Lord, bless his name; tell of his salvation from day to day” (Ps. 96:2). Many thanks to all the CSL and CTSFW students who contributed devotional reflections. A special note of thanks to my counterpart, Zachary Roll, who organized this effort at Concordia Seminary, St. Louis who has been a joy to work with and to get to know. A final note of thanks to Kim Hosier in the print shop and Rev. Dr. Paul Grime for their aid in completing this devotional booklet.https://scholar.csl.edu/osp/1021/thumbnail.jp

Temporal Dynamics of Host Molecular Responses Differentiate Symptomatic and Asymptomatic Influenza A Infection

Exposure to influenza viruses is necessary, but not sufficient, for healthy human hosts to develop symptomatic illness. The host response is an important determinant of disease progression. In order to delineate host molecular responses that differentiate symptomatic and asymptomatic Influenza A infection, we inoculated 17 healthy adults with live influenza (H3N2/Wisconsin) and examined changes in host peripheral blood gene expression at 16 timepoints over 132 hours. Here we present distinct transcriptional dynamics of host responses unique to asymptomatic and symptomatic infections. We show that symptomatic hosts invoke, simultaneously, multiple pattern recognition receptors-mediated antiviral and inflammatory responses that may relate to virus-induced oxidative stress. In contrast, asymptomatic subjects tightly regulate these responses and exhibit elevated expression of genes that function in antioxidant responses and cell-mediated responses. We reveal an ab initio molecular signature that strongly correlates to symptomatic clinical disease and biomarkers whose expression patterns best discriminate early from late phases of infection. Our results establish a temporal pattern of host molecular responses that differentiates symptomatic from asymptomatic infections and reveals an asymptomatic host-unique non-passive response signature, suggesting novel putative molecular targets for both prognostic assessment and ameliorative therapeutic intervention in seasonal and pandemic influenza

The COGs (context, object, and goals) in multisensory processing

Our understanding of how perception operates in real-world environments has been substantially advanced by studying both multisensory processes and “top-down” control processes influencing sensory processing via activity from higher-order brain areas, such as attention, memory, and expectations. As the two topics have been traditionally studied separately, the mechanisms orchestrating real-world multisensory processing remain unclear. Past work has revealed that the observer’s goals gate the influence of many multisensory processes on brain and behavioural responses, whereas some other multisensory processes might occur independently of these goals. Consequently, other forms of top-down control beyond goal dependence are necessary to explain the full range of multisensory effects currently reported at the brain and the cognitive level. These forms of control include sensitivity to stimulus context as well as the detection of matches (or lack thereof) between a multisensory stimulus and categorical attributes of naturalistic objects (e.g. tools, animals). In this review we discuss and integrate the existing findings that demonstrate the importance of such goal-, object- and context-based top-down control over multisensory processing. We then put forward a few principles emerging from this literature review with respect to the mechanisms underlying multisensory processing and discuss their possible broader implications

Federated learning enables big data for rare cancer boundary detection.

Although machine learning (ML) has shown promise across disciplines, out-of-sample generalizability is concerning. This is currently addressed by sharing multi-site data, but such centralization is challenging/infeasible to scale due to various limitations. Federated ML (FL) provides an alternative paradigm for accurate and generalizable ML, by only sharing numerical model updates. Here we present the largest FL study to-date, involving data from 71 sites across 6 continents, to generate an automatic tumor boundary detector for the rare disease of glioblastoma, reporting the largest such dataset in the literature (n = 6, 314). We demonstrate a 33% delineation improvement for the surgically targetable tumor, and 23% for the complete tumor extent, over a publicly trained model. We anticipate our study to: 1) enable more healthcare studies informed by large diverse data, ensuring meaningful results for rare diseases and underrepresented populations, 2) facilitate further analyses for glioblastoma by releasing our consensus model, and 3) demonstrate the FL effectiveness at such scale and task-complexity as a paradigm shift for multi-site collaborations, alleviating the need for data-sharing

Author Correction: Federated learning enables big data for rare cancer boundary detection.

10.1038/s41467-023-36188-7NATURE COMMUNICATIONS14