1,243 research outputs found

    Danos morais em relações de consumo

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    Orientador: Antônio Alves de Prado FilhoMonografia (graduação) - Universidade Federal do Paraná, Setor de Ciências Jurídicas, Curso de Graduação em DireitoOs consumidores encontram-se em uma evidente situação de vulnerabilidade no mercado de consumo, estando expostos a inúmeros abusos e desrespeitos por parte dos fornecedores de produtos e serviços. O meio mais eficiente para que tais abusos sejam coibidos parece ser uma efetiva aplicação do Código de Defesa do Consumidor, sendo de grande valia, para este fim, a utilização de um conceito mais amplo da figura dos danos morais, o qual deve ser utilizado como uma ferramenta para punir os abusos praticados pelos fornecedores, berm como para evitar que tais práticas abusivas voltem a ser por estes praticadas, passando assim, a indenização por danos morais, a possuir um caráter preventivo-pedagógico em relação aos maus comerciantes

    SEGURANÇA NO TRABALHO: A PERCEPÇÃO DE ACADÊMICOS DE UM CURSO SUPERIOR DE TECNOLOGIA EM GESTÃO PÚBLICA

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    O presente artigo contempla um estudo qualitativo acerca da percepção de acadêmicos de graduação em Curso Superior de Tecnologia em Gestão Pública, de uma instituição deCuritiba – PR, acerca das responsabilidades e misteres do gestor público quanto à Segurança no Trabalho. Os acadêmicos da unidade curricular “Segurança no Trabalho” se colocaram livremente assim como se dispuseram livremente a expressar suas percepções em entrevista não estruturada no ambiente de ensino-aprendizagem, tomaram parte na pesquisa duas turmas durante o ano de 2008. A responsabilidade trabalhista, civil e administrativa do gestor público acerca da segurança no trabalho emergiu como principal percepção entre os acadêmicos participantes da pesquisa

    Immediate effects of a high-velocity spine manipulation in paraspinal muscles activity of nonspecific chronic low-back pain subjects. Man Ther

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    a b s t r a c t High-velocity spinal manipulation is commonly adopted for treating chronic low-back pain (CLBP) and has been associated with changes in muscle activity, but the evidence is controversial. The aim of this study was to analyse the immediate effects of high-velocity spine manipulation on paraspinal activity during flexioneextension trunk movements. Forty nonspecific CLBP patients were randomised into two groups, manipulation (n ¼ 20) and control (n ¼ 20). While the manipulation group received high-velocity spine manipulation at the L4-L5 level, the control group remained lying in the same position. EMGrelated variables, perceived pain intensity (100 mm VAS) and finger-floor distance were collected before and after spinal manipulation at the L4-L5 level. EMG surface signals from the right and left paraspinal muscles (L5-S1 level) were acquired during trunk flexioneextension cycles. EMG activity during the static relaxation phase was significantly reduced following intervention for the manipulation group but not for the control group. The extension-phase EMG activity was also reduced after manipulation, but the flexion-phase EMG levels remained unchanged. Accordingly, the percent changes in FRR and ERR were significantly larger for the manipulation group compared to the control. The results suggest that a highvelocity spinal manipulation is able to acutely reduce abnormal EMG activity during the full-flexion static phase and activation during the extension phase

    Coleta de dados para revisão sistemática para resposta biológica in vitro de biocerâmicas à base de fosfatos de cálcio dopadas com Magnésio / Data collection for systematic review for in vitro biological response of magnesium-doped calcium phosphate-based bioceramics

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    A engenharia de tecidos ósseos vem estudando materiais biocompatíveis que possam ser utilizados na produção de implantes e próteses ósseas. As biocerâmicas à base de fosfatos de cálcio, como a hidroxiapatita, são biocompatíveis e possuem alta capacidade de osteointegração. A fim de obter respostas biológicas mais adequadas, pesquisas têm sido feitas dopando as biocerâmicas com íons metálicos, como Magnésio e o melhor conhecimento do efeito desses dopantes quando implantados, traz oportunidades de melhorias para as cirurgias e diminuição dos efeitos adversos. Este trabalho mostra a coleta de dados de um estudo preliminar sobre a avaliação das respostas biológica in vitro para biocerâmicas à base de fosfatos de cálcio modificadas com magnésio, para a posterior elaboração de uma revisão sistemática. Foram escolhidas palavras-chave relacionadas com o tema e realizado buscas nas bases de dados PubMed, EmBase, Scopus e Web Of Science utilizando o ensaio ALP com medidas de densidade óptica como critério de comparação. Em relação a coleta de dados, os resultados apresentaram falta de padronização e alta heterogeneidade em decorrência da arbitrariedade na concentração do dopante e nos períodos de avaliação das amostras, dificultando a comparação entre estudos. Com isso, esforços são necessários para o desenvolvimento de protocolos que viabilizem a obtenção de dados mais adequados para a comparação.

    Coleta de dados para revisão sistemática para resposta biológica in vitro de biocerâmicas à base de fosfatos de cálcio dopadas com Boro e Estrôncio / Data collection for systematic review of in vitro biological response of Boron and Strontium doped calcium phosphate bioceramics

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    A utilização de materiais biocerâmicos dopados com íons tem sido alvo de muitas pesquisas pela capacidade de melhorar o potencial de integração óssea de enxertos e implantes. Este trabalho propõe coletar dados para um estudo preliminar de avaliação dos efeitos na resposta biológica de biocerâmicas baseadas em fosfatos de cálcio, provocados pela adição de íons de estrôncio e boro. Este estudo preliminar visa a produção posterior de uma revisão sistemática. Foram escolhidas palavras-chaves para consultar as seguintes bases de dados: Scopus, PubMed, Embase e Web of Science. Os resultados obtidos passaram por duas fases de triagem para selecionar os artigos que podem ser utilizados para o estudo final e para a elaboração da meta-análise. Após a triagem, a meta-análise foi realizada com dados de cinco artigos utilizando ensaios de fosfatase alcalina (ALP) como parâmetro de comparação. Este estudo preliminar permitiu tomar conhecimento da produção científica publicada acerca do tema de interesse e das dificuldades que estarão presentes para a elaboração futura de uma revisão sistemática

    Can Clinical and Surgical Parameters Be Combined to Predict How Long It Will Take a Tibia Fracture to Heal? A Prospective Multicentre Observational Study: The FRACTING Study

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    Background. Healing of tibia fractures occurs over a wide time range of months, with a number of risk factors contributing to prolonged healing. In this prospective, multicentre, observational study, we investigated the capability of FRACTING (tibia FRACTure prediction healING days) score, calculated soon after tibia fracture treatment, to predict healing time. Methods. The study included 363 patients. Information on patient health, fracture morphology, and surgical treatment adopted were combined to calculate the FRACTING score. Fractures were considered healed when the patient was able to fully weight-bear without pain. Results. 319 fractures (88%) healed within 12 months from treatment. Forty-four fractures healed after 12 months or underwent a second surgery. FRACTING score positively correlated with days to healing: r = 0.63 (p < 0.0001). Average score value was 7.3 \ub1 2.5; ROC analysis showed strong reliability of the score in separating patients healing before versus after 6 months: AUC = 0.823. Conclusions. This study shows that the FRACTING score can be employed both to predict months needed for fracture healing and to identify immediately after treatment patients at risk of prolonged healing. In patients with high score values, new pharmacological and nonpharmacological treatments to enhance osteogenesis could be tested selectively, which may finally result in reduced disability time and health cost savings

    Association of kidney disease measures with risk of renal function worsening in patients with type 1 diabetes

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    Background: Albuminuria has been classically considered a marker of kidney damage progression in diabetic patients and it is routinely assessed to monitor kidney function. However, the role of a mild GFR reduction on the development of stage 653 CKD has been less explored in type 1 diabetes mellitus (T1DM) patients. Aim of the present study was to evaluate the prognostic role of kidney disease measures, namely albuminuria and reduced GFR, on the development of stage 653 CKD in a large cohort of patients affected by T1DM. Methods: A total of 4284 patients affected by T1DM followed-up at 76 diabetes centers participating to the Italian Association of Clinical Diabetologists (Associazione Medici Diabetologi, AMD) initiative constitutes the study population. Urinary albumin excretion (ACR) and estimated GFR (eGFR) were retrieved and analyzed. The incidence of stage 653 CKD (eGFR < 60 mL/min/1.73 m2) or eGFR reduction > 30% from baseline was evaluated. Results: The mean estimated GFR was 98 \ub1 17 mL/min/1.73m2 and the proportion of patients with albuminuria was 15.3% (n = 654) at baseline. About 8% (n = 337) of patients developed one of the two renal endpoints during the 4-year follow-up period. Age, albuminuria (micro or macro) and baseline eGFR < 90 ml/min/m2 were independent risk factors for stage 653 CKD and renal function worsening. When compared to patients with eGFR > 90 ml/min/1.73m2 and normoalbuminuria, those with albuminuria at baseline had a 1.69 greater risk of reaching stage 3 CKD, while patients with mild eGFR reduction (i.e. eGFR between 90 and 60 mL/min/1.73 m2) show a 3.81 greater risk that rose to 8.24 for those patients with albuminuria and mild eGFR reduction at baseline. Conclusions: Albuminuria and eGFR reduction represent independent risk factors for incident stage 653 CKD in T1DM patients. The simultaneous occurrence of reduced eGFR and albuminuria have a synergistic effect on renal function worsening

    Search for invisible decays of the Higgs boson produced via vector boson fusion in proton-proton collisions at s\sqrt{s} = 13 TeV

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    A search for invisible decays of the Higgs boson produced via vector boson fusion (VBF) has been performed with 101  fb1^{-1} of proton-proton collisions delivered by the LHC at s\sqrt{s} =13  TeV and collected by the CMS detector in 2017 and 2018. The sensitivity to the VBF production mechanism is enhanced by constructing two analysis categories, one based on missing transverse momentum and a second based on the properties of jets. In addition to control regions with Z and W boson candidate events, a highly populated control region, based on the production of a photon in association with jets, is used to constrain the dominant irreducible background from the invisible decay of a Z boson produced in association with jets. The results of this search are combined with all previous measurements in the VBF topology, based on data collected in 2012 (at s\sqrt{s} =8  TeV), 2015, and 2016, corresponding to integrated luminosities of 19.7, 2.3, and 36.3  fb1^{-1}, respectively. The observed (expected) upper limit on the invisible branching fraction of the Higgs boson is found to be 0.18 (0.10) at the 95% confidence level, assuming the standard model production cross section. The results are also interpreted in the context of Higgs-portal models

    Observation of the Bc+_\mathrm{c}^+ Meson in Pb-Pb and pp Collisions at sNN\sqrt{s_{\mathrm{NN}}} = 5.02 TeV and Measurement of its Nuclear Modification Factor

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    The Bc+_\mathrm{c}^+ meson is observed for the first time in heavy ion collisions. Data from the CMS detector are used to study the production of the Bc+_\mathrm{c}^+ meson in lead-lead (Pb-Pb) and proton-proton (pp) collisions at a center-of-mass energy per nucleon pair of sNN\sqrt{s_{\mathrm{NN}}} = 5.02 TeV , via the Bc+_\mathrm{c}^+ → (J/ψ → μ+^+μ^−+^+νμ decay. The Bc+_\mathrm{c}^+ nuclear modification factor, derived from the PbPb-to-pp ratio of production cross sections, is measured in two bins of the trimuon transverse momentum and of the PbPb collision centrality. The Bc+_\mathrm{c}^+meson is shown to be less suppressed than quarkonia and most of the open heavy-flavor mesons, suggesting that effects of the hot and dense nuclear matter created in heavy ion collisions contribute to its production. This measurement sets forth a promising new probe of the interplay of suppression and enhancement mechanisms in the production of heavy-flavor mesons in the quark-gluon plasma

    Measurement of the B0^{0}s_{s} → μ+^{+} μ^{-} decay properties and search for the B0^{0} → μ+^{+}μ^{-} decay in proton-proton collisions at √s = 13 TeV

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