Alien Registration- Pallanza, Flavia (Portland, Cumberland County)

https://digitalmaine.com/alien_docs/25626/thumbnail.jp

El cuerpo público coordinado

A lo largo de la historia las corrientes artísticas fueron aportando diferentes versiones de la realidad, buscando nuevas formas de producción, de interpretación y fundamentalmente de comunicación. La inclusión de nuevas tecnologías y el acceso a la información, además del vertiginoso ritmo de vida que esto genera, otorga mayores posibilidades para la comunicación y para producción artística. Nos identificamos como habitantes de un nuevo paradigma, en el que el trabajo multidisciplinar genera que los límites entre las artes se fundan y se complementen para crear nuevos lenguajes. Nos ubicamos en este contexto como protagonistas del panorama artístico y como arte educadoras.Eje 6: Discusiones teórico-conceptuales en torno al cuerpo. TalleresFacultad de Humanidades y Ciencias de la Educació

Population dynamics of the pioneer population of Daphnia parvula, Fordyce during the invasion of Lake Candia (Northern Italy)

Since the 1970s Daphnia parvula, Fordyce, originally distributed in the New World, has been invading Europe. In Italy D. parvula first appeared in the shallow, eutrophic Lake Candia (Piedmont, Northern Italy) during September 2002. Although several studies have documented D. parvula dispersal in European habitats, little is known about the life cycle and ecology of this invader in its new habitats. Invasion success depends on the ability of the invader population to perform well in the new ecosystem, which in turn results from the interaction between the characteristics of the invader and those of the invaded environment and its resident community. Early detection of D. parvula in the intensively studied Lake Candia offered an excellent opportunity to study the performance of the pioneer population and to document the early phases of invasion. Following the dynamics of the pioneer D. parvula population provided evidence of a high level of gamogenetic reproduction during most periods of population development. The production of males started at the onset of population growth prior to ephippia formation. The sex ratio ranged from 0.1 to 0.33 males per female with a maximum in October when males accounted for up to 24% of the total population density. The percentage of ephippia (free ephippia + ephippial females) out of the total population density ranged from 3 to 23%. The large pool of resting eggs produced by the pioneer population of D. parvula in Lake Candia might reflect a strategy for increasing the probability of survival and establishment in the new environment

Dietary fats significantly influence the survival of penumbral neurons in a permanent isquemic stroke rat model by modifying lipid mediators, inflammatory biomarkers, nos production, and redox-dependent apoptotic signals

Objective: Brain stroke is the third most important cause of death in developed countries. We studied the effect of different dietary lipids on the outcome of a permanent ischemic stroke rat model. Methods: Wistar rats were fed diets containing 7% commercial oils (S, soybean; O, olive; C, coconut; G, grape seed) for 35 d. Stroke was induced by permanent middle cerebral artery occlusion. Coronal slices from ischemic brains and sham-operated animals were supravitally stained. Penumbra and core volumes were calculated by image digitalization after 24, 48, and 72 h poststroke. Homogenates and mitochondrial fractions were prepared from different zones and analyzed by redox status, inflammatory markers, ceramide, and arachidonate content, phospholipase A2, NOS, and proteases. Results: Soybean (S) and G diets were mainly prooxidative and proinflammatory by increasing the liberation of arachidonate and its transformation into prostaglandins. O was protective in terms of redox homeostatic balance, minor increases in lipid and protein damage, conservation of reduced glutathione, protective activation of NOS in penumbra, and net ratio of anti-to proinflammatory cytokines. Apoptosis (caspase-3, milli- and microcalpains) was less activated by O than by any other diet. Conclusion: Dietary lipids modulate NOS and PLA2 activities, ceramide production, and glutathione import into the mitochondrial matrix, finally determining the activation of the two main protease systems involved in programmed cell death. Olive oil appears to be a biological source for the isolation of protective agents that block the expansion of brain core at the expense of penumbral neurons.Facultad de Ciencias MédicasInstituto de Investigaciones Bioquímicas de La Plat

Dietary fats significantly influence the survival of penumbral neurons in a permanent isquemic stroke rat model by modifying lipid mediators, inflammatory biomarkers, nos production, and redox-dependent apoptotic signals

Objective: Brain stroke is the third most important cause of death in developed countries. We studied the effect of different dietary lipids on the outcome of a permanent ischemic stroke rat model. Methods: Wistar rats were fed diets containing 7% commercial oils (S, soybean; O, olive; C, coconut; G, grape seed) for 35 d. Stroke was induced by permanent middle cerebral artery occlusion. Coronal slices from ischemic brains and sham-operated animals were supravitally stained. Penumbra and core volumes were calculated by image digitalization after 24, 48, and 72 h poststroke. Homogenates and mitochondrial fractions were prepared from different zones and analyzed by redox status, inflammatory markers, ceramide, and arachidonate content, phospholipase A2, NOS, and proteases. Results: Soybean (S) and G diets were mainly prooxidative and proinflammatory by increasing the liberation of arachidonate and its transformation into prostaglandins. O was protective in terms of redox homeostatic balance, minor increases in lipid and protein damage, conservation of reduced glutathione, protective activation of NOS in penumbra, and net ratio of anti-to proinflammatory cytokines. Apoptosis (caspase-3, milli- and microcalpains) was less activated by O than by any other diet. Conclusion: Dietary lipids modulate NOS and PLA2 activities, ceramide production, and glutathione import into the mitochondrial matrix, finally determining the activation of the two main protease systems involved in programmed cell death. Olive oil appears to be a biological source for the isolation of protective agents that block the expansion of brain core at the expense of penumbral neurons.Facultad de Ciencias MédicasInstituto de Investigaciones Bioquímicas de La Plat

Dietary fats significantly influence the survival of penumbral neurons in a permanent isquemic stroke rat model by modifying lipid mediators, inflammatory biomarkers, nos production, and redox-dependent apoptotic signals

Objective: Brain stroke is the third most important cause of death in developed countries. We studied the effect of different dietary lipids on the outcome of a permanent ischemic stroke rat model. Methods: Wistar rats were fed diets containing 7% commercial oils (S, soybean; O, olive; C, coconut; G, grape seed) for 35 d. Stroke was induced by permanent middle cerebral artery occlusion. Coronal slices from ischemic brains and sham-operated animals were supravitally stained. Penumbra and core volumes were calculated by image digitalization after 24, 48, and 72 h poststroke. Homogenates and mitochondrial fractions were prepared from different zones and analyzed by redox status, inflammatory markers, ceramide, and arachidonate content, phospholipase A2, NOS, and proteases. Results: Soybean (S) and G diets were mainly prooxidative and proinflammatory by increasing the liberation of arachidonate and its transformation into prostaglandins. O was protective in terms of redox homeostatic balance, minor increases in lipid and protein damage, conservation of reduced glutathione, protective activation of NOS in penumbra, and net ratio of anti-to proinflammatory cytokines. Apoptosis (caspase-3, milli- and microcalpains) was less activated by O than by any other diet. Conclusion: Dietary lipids modulate NOS and PLA2 activities, ceramide production, and glutathione import into the mitochondrial matrix, finally determining the activation of the two main protease systems involved in programmed cell death. Olive oil appears to be a biological source for the isolation of protective agents that block the expansion of brain core at the expense of penumbral neurons.Facultad de Ciencias MédicasInstituto de Investigaciones Bioquímicas de La Plat

Characterisation of the selective binding of antibiotics vancomycin and teicoplanin by the VanS receptor regulating type A vancomycin resistance in the enterococci

A-type resistance towards "last-line" glycopeptide antibiotic vancomycin in the leading hospital acquired infectious agent, the enterococci, is the most common in the UK. Resistance is regulated by the VanRASA two-component system, comprising the histidine sensor kinase VanSA and the partner response regulator VanRA. The nature of the activating ligand for VanSA has not been identified, therefore this work sought to identify and characterise ligand(s) for VanSA. In vitro approaches were used to screen the structural and activity effects of a range of potential ligands with purified VanSA protein. Of the screened ligands (glycopeptide antibiotics vancomycin and teicoplanin, and peptidoglycan components N-acetylmuramic acid, D-Ala-D-Ala and Ala-D-y-Glu-Lys-D-Ala-D-Ala) only glycopeptide antibiotics vancomycin and teicoplanin were found to bind VanSA with different affinities (vancomycin 70 μM; teicoplanin 30 and 170 μM), and were proposed to bind via exposed aromatic residues tryptophan and tyrosine. Furthermore, binding of the antibiotics induced quicker, longer-lived phosphorylation states for VanSA, proposing them as activators of type A vancomycin resistance in the enterococci. [Abstract copyright: Copyright © 2017. Published by Elsevier B.V.

Notulae to the Italian alien vascular flora: 12

In this contribution, new data concerning the distribution of vascular flora alien to Italy are presented. It includes new records, confirmations, exclusions, and status changes for Italy or for Italian administrative regions. Nomenclatural and distribution updates published elsewhere are provided as Suppl. material 1