11 research outputs found

    Manual de producción de un programa de 30 minutos

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    Para las personas que tengan en mente realizar un programa segmento no mayor de 30 minutos, ya sea un tema de interés social o particular, nuestro manual lo guiará en ¿cómo desarrollarlo?, haciendo un cronograma de trabajo, una estadística de presupuesto y que recursos técnicos y humanos necesita. En nuestro corto viaje por el mundo de la producción, partiremos de la idea principal y desarrollo de guiones y escaletas, considerando la realización y filmación, hasta la elaboración de la post- producción del mismo. Paso a paso se explicará cada etapa de la producción, tomando a "Psicólogo en casa”, una revista televisiva familiar, como ejemplo de ¿cuál es el resultado del programa que pueden realizar?, y que además podrá desarrollarse como un proyecto que saldrá al aire independientemente o como parte de un programa más grande. Nuestros lectores podrán utilizar este manual como guía para proyectar todas sus ideas en cada pantalla de televisión de la ciudad

    Estudio de las coinfecciones por otros patógenos respiratorios en pacientes pediátricos con diagnóstico de covid-19

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    Introducción: La coinfección de COVID-19 con otros patógenos respiratorios en pediatría ha sido poco estudiada. Resulta de interés conocer las características y cuadro clínico de pacientes que presenten coinfecciones con COVID-19. Objetivo: Estudiar la coinfección de SARS-CoV-2 con patógenos incluidos en el Panel RP 2.0 FilmArray® en muestras de pacientes pediátricos en un hospital del tercer nivel. Materiales y métodos: Durante abril a agosto de 2021 se realizó un estudio prospectivo descriptivo sobre 21 muestras de Hisopado Nasofaríngeo de pacientes pediátricos positivos para SARS-CoV-2 (iAMP® COVID-19 Detection Kit de Atila Biosystems). Se procesaron por PCR multiplex Filmarray® RP 2.0. Luego se describieron las características y síntomas de los pacientes. Resultados: 12/21 (60%) fueron pacientes ambulatorios y 8/21 (40%) internados. El 57% de los pacientes fueron mayores de 5 años, el 24% menores de 1 año y el 19% entre 1 y 5 años. El síntoma más frecuente fue fiebre 18/21 (86%). El 90,5% (19/21) de las muestras no mostraron detección de otros patógenos. En una muestra se detectó Rhino/enterovirus y en otra Coronavirus NL63; ambas pertenecieron a dos pacientes con enfermedades de base. Conclusión: La tasa de coinfecciones fue del 9,5%. Este número podría deberse a la baja circulación de patógenos respiratorios en un contexto con medidas de prevención de los contagios. En el estado actual de incremento de circulación de virus respiratorios endémicos, es de interés la búsqueda de coinfecciones con COVID-19.Introduction: The co-infection of COVID-19 with other respiratory pathogens in pediatrics has been little studied. It is of interest to know the characteristics and clinical picture of patients who present co-infections with COVID-19. Objective: To study the co-infection of SARS-CoV-2 with pathogens included in the RP Panel 2.0 FilmArray® in samples from pediatric patients in a third-level hospital. Materials and methods: During April to August 2021, a prospective descriptive study was conducted on 21 Nasopharyngeal Swab samples from pediatrics patients positive for SARS-CoV-2 (iAMP® COVID- 19 Detection Kit from Attila Biosystems). They were processed by PCR multiplex Filmarray® RP 2.0. The characteristics and symptoms of the patients were then described. Results: 12/21 (60%) were outpatients and 8/21 (40%) were hospitalized. 57% of patients were older than 5 years, 24% under 1 year and 19% between 1 and 5 years. The most frequent symptom was fever 18/21 (86%). 90,5% (19/21) of the samples showed no detection of other pathogens. Rhino/enterovirus was detected in one sample and NL63 in another Coronavirus; both belonged to two patients with underlying diseases. Conclusion: The rate of co-infections was 9,5%. This number could be due to the low circulation of respiratory pathogens in a context with measures to prevent contagion. In the current state of increased circulation of endemic respiratory viruses, the search for co-infections with COVID-19 is of interest

    CIBERER : Spanish national network for research on rare diseases: A highly productive collaborative initiative

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    Altres ajuts: Instituto de Salud Carlos III (ISCIII); Ministerio de Ciencia e Innovación.CIBER (Center for Biomedical Network Research; Centro de Investigación Biomédica En Red) is a public national consortium created in 2006 under the umbrella of the Spanish National Institute of Health Carlos III (ISCIII). This innovative research structure comprises 11 different specific areas dedicated to the main public health priorities in the National Health System. CIBERER, the thematic area of CIBER focused on rare diseases (RDs) currently consists of 75 research groups belonging to universities, research centers, and hospitals of the entire country. CIBERER's mission is to be a center prioritizing and favoring collaboration and cooperation between biomedical and clinical research groups, with special emphasis on the aspects of genetic, molecular, biochemical, and cellular research of RDs. This research is the basis for providing new tools for the diagnosis and therapy of low-prevalence diseases, in line with the International Rare Diseases Research Consortium (IRDiRC) objectives, thus favoring translational research between the scientific environment of the laboratory and the clinical setting of health centers. In this article, we intend to review CIBERER's 15-year journey and summarize the main results obtained in terms of internationalization, scientific production, contributions toward the discovery of new therapies and novel genes associated to diseases, cooperation with patients' associations and many other topics related to RD research

    Hato Lechero Potrerillo

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    El Hato Lechero Potrerillo es un proyecto que pretende iniciar con un lote de 120 hembras vacunas mestizas fruto de cruces con toros de raza lechera pura, ya que la selección primordial de estas vacas es su desarrollo adaptado al medio ambiente de la zona geográfica donde se ubica la finca. La selección de animales con características ideales como: fenotipo, sanidad animal y desarrollo ideal; y las variables como caderas amplias, el tamaño y proyección de ubre, altura de la cruz del animal proporcional a la medida de la altura de la cruz del animal proporcional a la medida de la altura de la cruz de la raza, pelaje, constituyen factores básicos al momento de escoger el lote bivino del hato lechero. En la finca Potrerillo se desea obtener las mejores condiciones de sanidad y cuidado adecuado para los animales. Condiciones que van a influir en la producción de leche con parámetros de cantidad y calidad, y así lograr cumplir los objetivos y expectativas trazadas

    Una salida desesperada

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    En este caso se presenta la necesidad de reestructuración financiera para un ingenio azucarero con capital colombiano como una salida para su difícil situación financiera. En concordancia con lo anterior, es necesario hacer un detallado análisis financiero de la empresa, determinar cuál es la estructura de capital actual y cuál sería la que maximice su valor; ésta última debe servir de guía a la administración para tomar las decisiones sobre el futuro del ingenio

    Urological cancer treatment by a multidisciplinary team throughout the COVID-19 pandemic : what have we learned?

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    Introduction It is known that cancer care is best approached by a multidisciplinary team (MDT). This became specifically true in the COVID-19 pandemic in which choices for urological cancer treatment are influenced by many factors. In some cases, delayedQ4Revista Nacional - IndexadaBN

    Transforming growth factor-β1 functional polymorphisms in myeloablative sibling hematopoietic stem cell transplantation

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    Hematopoietic stem cell transplantation (HSCT) with sibling donors (s.d.) is a life-saving intervention for patients with hematologicalmalignancies. Numerous genetic factors have a role in transplant outcome. Several functional polymorphisms have been identifiedin TGF-β1 gene, such as single-nucleotide polymorphism (SNP) at +29C4T within exon 1. Two hundred and forty five patient/donorpairs who underwent a s.d. HSCT in our centers were genotyped for this SNP. In the myeloablative cohort, +29CC donors wereassociated with an increase in severe chronic GvHD (32% vs 16%, hazard ratio (HR) 9.0, P = 0.02). Regarding survival outcomes,+29CC patients developed higher non relapse mortality (NRM) (1?5 years CC 28?32% vs TC/TT 7?10%; HR 5.1, P = 0.01). Recipientsof +29TT donors experienced a higher relapse rate (1?5 years TT 37?51% vs TC 19?25% vs CC 13%?19%; HR 2.4, P = 0.01) witha decreased overall survival (OS) (1?5 years TT 69?50% vs TC/CC 77?69%; HR 1.9, P = 0.05). Similar to previous myeloablativeunrelated donors HSCT results, we confirmed that +29CC patients had higher NRM. In addition we found that +29TT donors mightbe associated with a higher relapse rate and lower OS. These results should be confirmed in larger series. Identification of theseSNPs will allow personalizing transplant conditioning and immunosuppressant regimens, as well as assisting in the choice of themost appropriate donor.Fil: Berro, Mariano. Universidad Austral; ArgentinaFil: Palau Nagore, Maria Virginia. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Medicina Experimental. Academia Nacional de Medicina de Buenos Aires. Instituto de Medicina Experimental; ArgentinaFil: Rivas, M. M.. Universidad Austral; ArgentinaFil: Longo, P.. Universidad Austral; ArgentinaFil: Foncuberta, Cecilia. Instituto Alexander Fleming; ArgentinaFil: Vitriu, Adriana. Instituto Alexander Fleming; ArgentinaFil: Remaggi, Guillermina. Fundaleu; ArgentinaFil: Martinez Rolón, Juliana. Fundaleu; ArgentinaFil: Jaimovich, Gregorio. Fundación Favaloro; ArgentinaFil: Requejo, Alejandro. Fundación Favaloro; ArgentinaFil: Feldman, Leonardo. Fundación Favaloro; ArgentinaFil: Padros, Karín. Fundación Favaloro; ArgentinaFil: Rodriguez, María Beatriz. Fundación Favaloro; ArgentinaFil: Shaw, B. E.. Medical College Of Wisconsin; Estados UnidosFil: Larripa, Irene Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Medicina Experimental. Academia Nacional de Medicina de Buenos Aires. Instituto de Medicina Experimental; ArgentinaFil: Belli, Carolina Bárbara. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Medicina Experimental. Academia Nacional de Medicina de Buenos Aires. Instituto de Medicina Experimental; ArgentinaFil: Kusminsky, Gustavo. Universidad Austral; Argentin

    <i>Burkholderia puraquae</i> sp. nov., a novel species of the <i>Burkholderia cepacia</i> complex isolated from hospital settings and agricultural soils

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    Bacteria from the Burkholderia cepacia complex (Bcc) are capable of causing severe infections in patients with cystic fibrosis (CF). These opportunistic pathogens are also widely distributed in natural and man-made environments. After a 12-year epidemiological surveillance involving Bcc bacteria from respiratory secretions of Argentinean patients with CF and from hospital settings, we found six isolates of the Bcc with a concatenated species-specific allele sequence that differed by more than 3% from those of the Bcc with validly published names. According to the multilocus sequence analysis (MLSA), these isolates clustered with the agricultural soil strain, Burkholderia sp. PBP 78, which was already deposited in the PubMLST database. The isolates were examined using a polyphasic approach, which included 16S rRNA, recA, Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS), DNA base composition, average nucleotide identities (ANIs), fatty acid profiles, and biochemical characterizations. The results of the present study demonstrate that the seven isolates represent a single novel species within the Bcc, for which the name Burkholderia puraquae sp. nov. is proposed. Burkholderia puraquae sp. nov. CAMPA 1040T (=LMG 29660T=DSM 103137T) was designated the type strain of the novel species, which can be differentiated from other species of the Bcc mainly from recA gene sequence analysis, MLSA, ANIb, MALDI-TOF MS analysis, and some biochemical tests, including the ability to grow at 42 ºC, aesculin hydrolysis, and lysine decarboxylase and β-galactosidase activities.Facultad de Ciencias ExactasCentro de Investigación y Desarrollo en Fermentaciones IndustrialesInstituto de Biotecnologia y Biologia Molecula

    Effects of pre-operative isolation on postoperative pulmonary complications after elective surgery: an international prospective cohort study

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