4,377 research outputs found
On the frequency of N2H+ and N2D+
Context : Dynamical studies of prestellar cores search for small velocity
differences between different tracers. The highest radiation frequency
precision is therefore required for each of these species. Aims : We want to
adjust the frequency of the first three rotational transitions of N2H+ and N2D+
and extrapolate to the next three transitions. Methods : N2H+ and N2D+ are
compared to NH3 the frequency of which is more accurately known and which has
the advantage to be spatially coexistent with N2H+ and N2D+ in dark cloud
cores. With lines among the narrowests, and N2H+ and NH3 emitting region among
the largests, L183 is a good candidate to compare these species. Results : A
correction of ~10 kHz for the N2H+ (J:1-0) transition has been found (~0.03
km/s) and similar corrections, from a few m/s up to ~0.05 km/s are reported for
the other transitions (N2H+ J:3-2 and N2D+ J:1-0, J:2-1, and J:3-2) compared to
previous astronomical determinations. Einstein spontaneous decay coefficients
(Aul) are included
Detection of interstellar H_2D^+ emission
We report the detection of the 1_{10}-1_{11} ground state transition of
ortho-H_2D^+ at 372.421 GHz in emission from the young stellar object NGC 1333
IRAS 4A. Detailed excitation models with a power-law temperature and density
structure yield a beam-averaged H_2D^+ abundance of 3 x 10^{-12} with an
uncertainty of a factor of two. The line was not detected toward W 33A, GL
2591, and NGC 2264 IRS, in the latter source at a level which is 3-8 times
lower than previous observations. The H_2D^+ data provide direct evidence in
support of low-temperature chemical models in which H_2D^+ is enhanced by the
reaction of H_3^+ and HD. The H_2D^+ enhancement toward NGC 1333 IRAS 4A is
also reflected in the high DCO^+/HCO^+ abundance ratio. Simultaneous
observations of the N_2H^+ 4-3 line show that its abundance is about 50-100
times lower in NGC 1333 IRAS 4A than in the other sources, suggesting
significant depletion of N_2. The N_2H^+ data provide independent lower limits
on the H_3^+ abundance which are consistent with the abundances derived from
H_2D^+. The corresponding limits on the H_3^+$ column density agree with recent
near-infrared absorption measurements of H_3^+ toward W 33A and GL 2591.Comment: Standard AAS LaTeX format (15 pages + 2 figures
Leaders\u2019 competence and warmth: Their relationships with employees\u2019 well-being and organizational effectiveness
The aim of this work was to investigate competence and warmth \u2014 the two basic dimensions of social judgment \u2014 as dimensions employees use to evaluate their supervisors. A mediation model was tested in which supervisor\u2019s perceived competence and warmth were associated with relevant outcomes (lower burnout, weaker turnover intentions, more frequent citizenship behaviors) through the mediation of affective organizational commitment (AOC). In Study 1, data were collected from employees of a company in the water service sector. In Study 2, participants were financial promoters. In Study 3, the sample included employees from different organizations. As hypothesized, the perception of one\u2019s supervisor as competent (Studies 1-3) and warm (Study 3) was related to employees\u2019 lower burnout, weaker turnover intentions, more frequent prosocial behaviors through the mediation of AOC. Theoretical and practical implications of findings are discussed
Towards a new critical edition of the scholia to the Iliad: a specimen
An on-going new critical edition is presented, designed to gather together for the first time all the scholia vetera to the Iliad transmitted by the manuscript tradition. A short introduction is followed by a sample of the new critical text (i.e. sch. in Iliadem A 6-11), compared to the corresponding part in Hartmut Erbse's edition
Influence of non-structural localized inertia on free vibration response of thin-walled structures by variable kinematic beam formulations
Variable kinematic beam theories are used in this paper to carry out vibration analysis of isotropic thin-walled structures subjected to non-structural localized inertia. Arbitrarily enriched displacement fields for beams are hierarchically obtained by using the Carrera Unified Formulation (CUF). According to CUF, kinematic fields can be formulated either as truncated Taylor-like expansion series of the generalized unknowns or by using only pure translational variables by locally discretizing the beam cross-section through Lagrange polynomials. The resulting theories were, respectively, referred to as TE (Taylor Expansion) and LE (Lagrange Expansion) in recent works. If the finite element method is used, as in the case of the present work, stiffness and mass elemental matrices for both TE and LE beam models can be written in terms of the same fundamental nuclei. The fundamental nucleus of the mass matrix is opportunely modified in this paper in order to account for non-structural localized masses. Several beams are analysed and the results are compared to those from classical beam theories, 2D plate/shell, and 3D solid models from a commercial FEM code. The analyses demonstrate the ineffectiveness of classical theories in dealing with torsional, coupling, and local effects that may occur when
localized inertia is considered. Thus the adoption of higher-order beam models is mandatory. The results highlight the efficiency of the proposed models and, in particular, the enhanced capabilities of LE modelling approach, which is able to reproduce solid-like analysis with very low computational costs
Operator product expansion coefficients from the nonperturbative functional renormalization group
Using the nonperturbative functional renormalization group (FRG) within the Blaizot-M\'endez-Galain-Wschebor approximation, we compute the operator product expansion (OPE) coefficient associated with the operators and in the three-dimensional universality class and in the Ising universality class () in dimensions . When available, exact results and estimates from the conformal bootstrap and Monte-Carlo simulations compare extremely well to our results, while FRG is able to provide values across the whole range of and considered
Factors influencing resident satisfaction and fellowship selection in orthopaedic training programs: An American Orthopaedic Association North American Traveling Fellowship project
The n-acetyl phenylalanine glucosamine derivative attenuates the inflammatory/catabolic environment in a chondrocyte-synoviocyte co-culture system
Osteoarthritis (OA), the most prevalent degenerative joint disease, still lacks a true disease-modifying therapy. The involvement of the NF-κB pathway and its upstream activating kinases in OA pathogenesis has been recognized for many years. The ability of the N-acetyl phenylalanine glucosamine derivative (NAPA) to increase anabolism and reduce catabolism via inhibition of IKKα kinase has been previously observed in vitro and in vivo. The present study aims to confirm the chondroprotective effects of NAPA in an in vitro model of joint OA established with primary cells, respecting both the crosstalk between chondrocytes and synoviocytes and their phenotypes. This model satisfactorily reproduces some features of the previously investigated DMM model, such as the prominent induction of ADAMTS-5 upon inflammatory stimulation. Both gene and protein expression analysis indicated the ability of NAPA to counteract key cartilage catabolic enzymes (ADAMTS-5) and effectors (MCP-1). Molecular analysis showed the ability of NAPA to reduce IKKα nuclear translocation and H3Ser10 phosphorylation, thus inhibiting IKKα transactivation of NF-κB signalling, a pivotal step in the NF-κB-dependent gene expression of some of its targets. In conclusion, our data confirm that NAPA could truly act as a disease-modifying drug in OA
Nanofiller for the mechanical reinforcement of maltodextrins orodispersible films
One of the most critical quality attributes of orodispersible films (ODFs) is related to the development of dosage forms with tensile properties suitable for the packaging and patient's handling. Aiming to develop a strategy to reinforce the tensile properties, the current work reported the feasibility to improve the tensile strength of maltodextrins (MDX) based ODFs by adding an amorphous water insoluble nanofiller, namely polyvinylacetate (PVAc). The possible interactions between components investigated by DSC and ATR-FTIR spectroscopy revealed that MDX and PVAc were immiscible; even if, the presence of plasticizers permitted the homogeneous dispersion of PVAc in the film until the 10% w/w concentration was reached. As a consequence, PVAc nanoparticles was found to be an effective reinforcing agent only at the concentrations of 3 and 5% w/w. In this optimal range, the tensile strength increased at least 1.5 fold and the elastic modulus increased at least 4 times
Guest editorial of MAMS special issue on: Applications of Unified Formulation and advanced theories using several numerical approaches
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