Physiological variables and burden in adult children of cancer patients

La presente investigación tuvo como objetivo evaluar el modo como los hijos adultos reaccionan frente a la enfermedad oncológica de los progenitores. Este estudio incluye dos muestras, cada una constituida por 78 sujetos. Así, una de las muestras corresponde a los hijos adultos con progenitores en situación oncológica. La otra incluye la participación de los hijos adultos con padres saludables. Los instrumentos utilizados fueron el Burden Assesment Scale y el International Affective Picture System. Los resultados indican que hay diferencias entre las dos muestras. Se constata que los hijos cuidadores de enfermos oncológicos presentan niveles más elevados de sobrecarga familiar y valores más elevados en los registros psicofisiológicos, lo que significa que manifiestan una mayor reactividad emocional.The present study have as main purpose assess how the adult children react to malignant disease of the parents. This study includes two samples, each of them consisting of 78 subjects. One sample corresponds to adult children in a situation of parental cancer. The other includes the participation of adult children with healthy parents. The measures used were the Burden Assessment Scale as well as the International Affective Picture System. The results indicate that there are differences between the children of cancer patients and children of healthy parents. It appears that the caregiving children have higher levels of familiar burden and higher values in psychophysiological records, which means higher reactivity towards the emotional stimuli.(undefined

Programmes de soutien par les pairs dans les domaines de la médecine et des sciences infirmières : recension systématique et revue narrative

Peer-provided services exist in many different domains and professions. However, there is a knowledge gap in the existing programs’ descriptions and grouping that hinders creating new high-quality peer support programs. The objectives of this article are two-fold in describing existing peer support programs published in the literature in the medical field and evaluating their descriptive quality. Six electronic databases, grey literature, and reference lists were systematically searched. Studies reporting the existence of a support program delivered by peers and its description or methodology were included. Studies targeting patients and children were excluded. 11 articles were included in the qualitative synthesis and explored in detail. A total of 2155 peers participated in support programs in the fields of medicine, nursing, or both. Programs in other professional fields were not found. Programs were described in five different countries. Three methods of peer support delivery were found: in person, online, and mixed varying in their goals, duration, peer training supervision and participant demographics and number. Program descriptions were rated as good, fair, or poor using a verified rating scale.  There are numerous well-described programs varying in their methodology and type of delivery. Thus, the emergence of new programs can be based on such models that have been well-described in the literature.Les services fournis par les pairs existent dans de nombreux domaines et professions. Cependant, les connaissances en matière de description et de regroupement des programmes existants sont lacunaires, entravant ainsi la création de nouveaux programmes de soutien par les pairs de qualité. Le présent article vise d’une part à décrire les programmes actuels de soutien par les pairs dont fait état la littérature médicale et d’autre part à évaluer leur qualité descriptive. Une recherche systématique a été effectuée dans six bases de données électroniques, dans la littérature grise et dans les listes de références. Toutes les études présentant un programme de soutien fourni par des pairs et sa description ou sa méthodologie ont été incluses. Les études ciblant les patients et les enfants ont été exclues. Onze articles ont été inclus dans la synthèse qualitative et explorés en détail. Au total, 2155 pairs ont participé à un programme de soutien en médecine, en sciences infirmières ou dans les deux domaines. Aucun programme n’a été trouvé dans d’autres domaines professionnels. Les programmes décrits proviennent de cinq pays différents. Trois méthodes de soutien par les pairs ont été trouvées : en personne, en ligne et mixte. Les objectifs, la durée, la supervision de la formation par les pairs, les données démographiques des participants et leur nombre varient d’un programme à l’autre. Les descriptions de programmes ont été évaluées selon une échelle d’évaluation validée comme bonnes, acceptables ou médiocres. Il existe de nombreux programmes, bien décrits, qui varient en termes de méthodologie et de type de prestation. Aussi, la création de nouveaux programmes pourra s’appuyer sur les modèles qui sont bien décrits dans la littérature

Actividad antiagregante plaquetaria de extractos metanolicos de liquenes de la Region del Maule

68 p.En Chile, los metabolitos secundarios sintetizados y acumulados en los líquenes no han sido estudiados especialmente en lo que concierne a sus posibles usos clínicos y menos utilizados como apoyo a tratamientos médicos. En la actualidad, las propiedades antiagregantes y antitrombóticas plaquetarias de los extractos liquénicos son poco conocidas, es por esto que, este estudio nace como una inquietud de buscar nuevas inquietudes para inhibir la agregación plaquetaria, a las actualmente utilizadas. Los líquenes utilizados en este estudio fueron colectados en el mes de Enero del 2010 de sistemas rocosos de los alrededores de la Laguna del Maule, Región del Maule. Durante la realización de este estudio los líquenes fueron limpiados, secados, pesados y triturados para proceder a la extracción de sus metabolitos secundarios mediante una batería de solventes de polaridad variable. La actividad antiagregante de los extractos metanólicos de Umbilicaria deusta y Rhizoplaca melanophthalma, fueron investigadas in vitro mediante la técnica escrita por Born en 1962, utilizando plasma rico en plaquetas. Los extractos mostraron efecto inhibidor de la agregación plaquetaria de un 37,16 % para U. deusta y 64,99 % para R. melanophthalma a una concentración de 1 mg/ml, al inducir la reacción con ADP 8 M, esta última especie al mostrar mayor actividad se le midió la concentración mínima inhibitoria (IC50) aproximada, obteniendo un valor de 0,634 mg/ml. Ambos extractos crudos fueron fraccionados mediante la técnica de cromatográfica de capa fina (preparativa) y posteriormente se evaluó su actividad antiagregante a una concentración de 0,5 mg/ml. Las fracciones más activas se analizaron por Espectrometría de Masas con Ionización por Electrospray, obteniendo la masa de los principales metabolitos presentes en las fracciones

A Arte no Ensino e Aprendizagem da Simetria: Uma experiência no2.º Ciclo do Ensino Básico

Este relatório foi elaborado no âmbito do Mestrado em Ensino do 1.º Ciclo do Ensino Básico e de Matemática e Ciências Naturais no 2º Ciclo do Ensino Básico e pretende evidenciar tanto o percurso feito no decorrer das práticas de ensino supervisionadas, como o projeto de investigação na área de Matemática que decorreu no 2.º Ciclo do Ensino Básico (doravante CEB). O relatório foi estruturado em duas partes. A primeira resume o trabalho desenvolvido ao nível das práticas de ensino supervisionadas, no 1.º e 2.º CEB (aprendizagens, dificuldades e reflexão sobre o trabalho desenvolvido) e, na segunda parte, é apresentado o projeto de investigação. O projeto desenvolvido tinha como objetivo principal a compreensão do conceito de Simetria, por alunos do 6.º ano de uma escola pertencente ao distrito de Viseu, a partir do trabalho com tarefas que envolviam a análise de elementos de Arte, utilizando materiais didáticos. Trata-se de um estudo de orientação naturalista que adota como instrumentos a observação direta, as notas de campo e a análise documental das resoluções dos alunos. Os resultados da investigação mostram que a utilização de materiais didáticos durante a resolução de tarefas auxilia a compreensão dos conceitos, por parte dos alunos, e que trabalhar tarefas para estudar a Simetria de elementos de Arte permite estudar contextos ricos e potencializadores de aprendizagens com significado, particularmente porque esses contextos não matemáticos e ligados ao dia a dia ajudam a dar significado à Matemática escolar, permitindo analisar e perspetivar uma Matemática menos abstrata.This report was elaborated in the scope of the Masters in Teaching of the 1st Cycle of Basic Education and of Mathematics and Natural Sciences in the 2nd Cycle of Basic Education and intends to highlight both the course done in the course of supervised teaching practices, as the research project in the area of Mathematics that took place in the 2nd Cycle of Basic Education (hereinafter CEB). The report was structured in two parts. The first one summarizes the work developed at the level of supervised teaching practices, in the 1st and 2nd CEB (learning, difficulties and reflection on the work developed) and, in the second part, the research project is presented. The main objective of the project was the understanding of the concept of Symmetry by students of the 6th year of a school belonging to the district of Viseu, starting from the work with tasks that involved the analysis of elements of Art using teaching materials. It is a naturalistic study that adopts as instruments direct observation, field notes and documentary analysis of students' resolutions. The results of the research show that the use of didactic materials during the task resolution helps the students to understand the concepts and that work tasks to study the symmetry of elements of the Art allows to study rich contexts and potentializers of learning with meanings, particularly because these non-mathematical and day-to-day contexts help to give meaning to school mathematics, allowing us to analyze and prospect a less abstract mathematics

Improved production of lutein and β-carotene by thermal and light intensity upshifts in the marine microalga Tetraselmis sp. CTP4

The industrial microalga Tetraselmis sp. CTP4 is a promising candidate for aquaculture feed, novel food, cosmeceutical and nutraceutical due to its balanced biochemical profile. To further upgrade its biomass value, carotenogenesis was investigated by testing four environmental factors, namely temperature, light intensity, salinity and nutrient availability over different growth stages. The most important factor for carotenoid induction in this species is a sufficient supply of nitrates leading to an exponential growth of the cells. Furthermore, high temperatures of over 30 degrees C compared to lower temperatures (10 and 20 degrees C) induced the accumulation of carotenoids in this species. Remarkably, the two different branches of carotenoid synthesis were regulated depending on different light intensities. Contents of beta-carotene were 3-fold higher under low light intensities (33 mu mol m(-2) s(-1)) while lutein contents increased 1.5-fold under higher light intensities (170 and 280 mu mol m(-2) s(-1)). Nevertheless, highest contents of carotenoids (8.48 +/- 0.47 mg g(-1) DW) were found upon a thermal upshift from 20 degrees C to 35 degrees C after only two days at a light intensity of 170 mu mol m(-2) s(-1). Under these conditions, high contents of both lutein and beta-carotene were reached accounting for 3.17 +/- 0.18 and 3.21 +/- 0.18 mg g(-1) DW, respectively. This study indicates that Tetraselmis sp. CTP4 could be a sustainable source of lutein and beta-carotene at locations where a robust, euryhaline, thermotolerant microalgal strain is required.Funding Agency Portuguese Foundation for Science and Technology UID/Multi/04326/2019 SFRH/BD/115325/2016 SFRH/BD/140143/2018 SFRH/BD/105541/2014 0055 ALGARED+ 05 INTERREG V-A -Espana Portugal project national Portuguese funding PPBI-POCI-01-0145-FEDER-22122 Nord Universityinfo:eu-repo/semantics/publishedVersio

Searching for new sources of innovative products for the food industry within halophyte aromatic plants: In vitro antioxidant activity and phenolic and mineral contents of infusions and decoctions of Crithmum maritimum L.

Aromatic halophyte plants are an outstanding source of bioactive compounds and natural products with potential use in the food industry. This work reports the in vitro antioxidant activity, toxicity, poly phenolic profile and mineral contents of infusions and decoctions from stems, leaves and flowers of Crithmum maritimum L, an aromatic and edible maritime halophyte (sea fennel). Aspalathus linearis (Burm.f.) Dahlg. (rooibos) herbal tea was used as a reference. Sea fennel's tisanes, particularly from leaves, were rich in phenolic compounds and five of them (p-hydroxybenzoic and ferulic acids, epicatechin, pyrocatechol and 4-hydroxybenzaldehyde) were here described in C maritimum for the first time. Chlorogenic acid was the dominant phenolic determined. Na was the most abundant mineral in all tisanes followed by Ca and Mg in leaves' tisanes and K in flowers. Sea fennel's samples had a similar antioxidant activity than those from A. linearis, and had no significant toxicity towards four different mammalian cell lines. Altogether, our results suggest that sea fennel can be a source of products and/or molecules for the food industry with antioxidant properties and minerals in the form, for example, of innovative health-promoting herbal beverages.FCT Investigator Programme [IF/00049/2012

Growth performance, biochemical composition and sedimentation velocity of Tetraselmis sp. CTP4 under different salinities using low-cost lab- and pilot-scale systems

Biomass harvesting is one of the most expensive steps of the whole microalgal production pipeline. Therefore, the present work aimed to understand the effect of salinity on the growth performance, biochemical composition and sedimentation velocity of Tetraselmis sp. CTP4, in order to establish an effective low-cost pilot-scale harvesting system for this strain. At lab scale, similar growth performance was obtained in cultures grown at salinities of 5, 10 and 20 g L-1 NaCl. In addition, identical settling velocities (2.4-3.6 cm h-1) were observed on all salinities under study, regardless of the growth stage. However, higher salinities (20 g L-1) promoted a significant increase in lipid contents in this strain compared to when this microalga was cultivated at 5 or 10 g L-1 NaCl. At pilot-scale, cultures were cultivated semi-continuously in 2.5-m3 tubular photobioreactors, fed every four days, and stored in a 1-m3 harvesting tank. Upon a 24-hour settling step, natural sedimentation of the microalgal cells resulted in the removal of 93% of the culture medium in the form of a clear liquid containing only vestigial amounts of biomass (0.07 ± 0.02 g L-1 dry weight; DW). The remaining culture was recovered as a highly concentrated culture (19.53 ± 4.83 g L-1 DW) and wet microalgal paste (272.7 ± 18.5 g L-1 DW). Overall, this method provided an effective recovery of 97% of the total biomass, decreasing significantly the harvesting costs.Agência financiadora Portuguese national budget P2020 Foundation for Science and Technology (FCT) CMAR/Multi/04326/2013 ALGARED+ 1398 EP - INTERREG V-A Espana Portugal project ALGACO2 project 023310 COST Action 1408 - European Network for Bio-products FCT SFRH/BD/105541/2014info:eu-repo/semantics/publishedVersio

Análise da lucratividade por linha de produto: pesquisa-ação aplicada em conjuntos cirúrgicos

TCC (Graduação) - Universidade Federal de Santa Catarina. Centro Socioeconômico. Curso de Ciências ContábeisO presente trabalho realiza o estudo a respeito de custos no ambiente organizacional de uma empresa que comercializa materiais ortopédicos. Tem por objetivo apurar a lucratividade dos produtos oferecidos pela empresa comercial, através do estudo de custos, para o auxílio à tomada de decisões. Apresenta uma revisão bibliográfica sobre conceitos de custos e os confrontam, formando a análise deles em uma experiência prática, através da configuração dos gastos e a apuração da lucratividade de cada produto. Trata-se de uma pesquisa exploratória, realizada por meio de uma pesquisa-ação, com abordagem qualitativa. Como resultado, a pesquisa permite observar o estudo de custos como uma importante ferramenta de gestão organizacional