51 research outputs found
Étude de la Relation Entre les Stratégies Cognitives et la Réussite Académique des Etudiants de l’Université de Kisangani
L’objectif de cette étude est celui de de déterminer les prédicteurs de la réussite académique des étudiants au sein de l’Université de Kisangani. À cet effet, les stratégies cognitives d’apprentissage déclarées par ces ont été croisées à leur rendement académique au cours de l’année académique 2020-2021. À l’issue du calcul de la régression logistique, il est apparu que la contribution des stratégies cognitives à la réussite des étudiants est de l’ordre de 0,164. La part d’intervention de chacune des sous-catégories est de 4,6% pour les stratégies de répétition, 3,8% en faveur des stratégies d’élaboration et 8% pour les stratégies d’organisation. Les enseignants doivent être sensibilisés et maitriser les stratégies qui rendent les étudiants efficients, ils doivent leur apprendre ces stratégies dans le but de maximiser leur réussite académique ; ils doivent leur apprendre à apprendre.
The objective of this study is to determine the predictors of academic success of students at the University of Kisangani. To this end, students' self-reported cognitive learning strategies were cross-tabulated with their academic performance during the 2020-2021 academic year. Once the logistic regression had been calculated, it emerged that the contribution of cognitive strategies to student success was of the order of 0.164. The contribution of each sub-category was 4.6% for rehearsal strategies, 3.8% for elaboration strategies and 8% for organisation strategies. Teachers must be aware of and master the strategies that make students efficient; they must teach them these strategies in order to maximise their academic success; they must teach them how to learn
Étude de la Relation Entre les Stratégies Cognitives et la Réussite Académique des Etudiants de l’Université de Kisangani
L’objectif de cette étude est celui de de déterminer les prédicteurs de la réussite académique des étudiants au sein de l’Université de Kisangani. À cet effet, les stratégies cognitives d’apprentissage déclarées par ces ont été croisées à leur rendement académique au cours de l’année académique 2020-2021. À l’issue du calcul de la régression logistique, il est apparu que la contribution des stratégies cognitives à la réussite des étudiants est de l’ordre de 0,164. La part d’intervention de chacune des sous-catégories est de 4,6% pour les stratégies de répétition, 3,8% en faveur des stratégies d’élaboration et 8% pour les stratégies d’organisation. Les enseignants doivent être sensibilisés et maitriser les stratégies qui rendent les étudiants efficients, ils doivent leur apprendre ces stratégies dans le but de maximiser leur réussite académique ; ils doivent leur apprendre à apprendre.
The objective of this study is to determine the predictors of academic success of students at the University of Kisangani. To this end, students' self-reported cognitive learning strategies were cross-tabulated with their academic performance during the 2020-2021 academic year. Once the logistic regression had been calculated, it emerged that the contribution of cognitive strategies to student success was of the order of 0.164. The contribution of each sub-category was 4.6% for rehearsal strategies, 3.8% for elaboration strategies and 8% for organisation strategies. Teachers must be aware of and master the strategies that make students efficient; they must teach them these strategies in order to maximise their academic success; they must teach them how to learn
Pim-1 : a new biomarker in pulmonary arterial hypertension
Provirus integration site for Moloney murine leukemia virus (Pim-1) is an oncoprotein overexpressed in lungs from pulmonary arterial hypertension (PAH) patients and involved in cell proliferation via the activation of the NFAT/STAT3 signaling pathway. We hypothesized that Pim-1 plasma levels would predict the presence of PAH and correlate with disease severity. Pim-1 plasma levels were measured at the time of catheterization in 49 PAH patients, including nonvasoreactive (n = 19) and vasoreactive idiopathic PAH (n = 5), and PAH related to connective tissue disease (n = 16) and congenital heart disease (n = 9). Fifty controls were also recruited. The capacity of Pim-1 to discriminate PAH from controls and its association with disease severity were assessed. Pim-1 plasma levels were higher in PAH than in controls (9.6 ± 4.0 vs. 7.2 ± 2.4 ng/mL, P < 0.01). Pim-1 appropriately discriminated proliferative PAH from controls (AUC = 0.78 to 0.94 using ROC curves). Among PAH patients, Pim-1 correlated with traditional markers of PAH severity. The 1-year survival was 97% and 47% for PAH patients with baseline Pim-1 levels lower and higher than 11.1 ng/mL, respectively (HR 11.4 (3.3–39.7); P <0.01). After adjustment for hemodynamic and biochemical variables, Pim-1 levels remained an independent predictor of mortality (P < 0.01). Pim-1 is a promising new biomarker in PAH
Compression progressive de modèles de plantes à base de cylindres généralisés
National audienceCe papier présente nos travaux récents sur la compression progressive de modèles de plantes à base de cylindres généralisés. Cette représentation multi-resolution est compatible avec une représentation sous forme de graphe orienté sans cycle, ce qui nous permet de bénéficier des techniques de streaming progressif proposées dans cheng07analytical. Un codage différentiel des plantes est présenté: pour un groupe choisi de branches on calcule une branche moyenne, et pour chaque branche, il reste à coder une transformation et des différences. En vue du streaming, nous identifions et exploitons deux types de dépendances: topologiques (entre branche fille et mère) et dues au codage différentiel. Nous obtenons un modèle progressif qui permet la sélection d'une représentation plus légère de la plante, tout en gardant la même densité de branches
Analysis of path integrals at low temperature : Box formula, occupation time and ergodic approximation
We study the low temperature behaviour of path integrals for a simple
one-dimensional model. Starting from the Feynman-Kac formula, we derive a new
functional representation of the density matrix at finite temperature, in terms
of the occupation times of Brownian motions constrained to stay within boxes
with finite sizes. From that representation, we infer a kind of ergodic
approximation, which only involves double ordinary integrals. As shown by its
applications to different confining potentials, the ergodic approximation turns
out to be quite efficient, especially in the low-temperature regime where other
usual approximations fail
Role for miR-204 in human pulmonary arterial hypertension
Reduced miR-204 expression facilitates the excessive proliferation and apoptosis resistance of pulmonary artery smooth muscle cells characteristic of human pulmonary arterial hypertension
The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance
INTRODUCTION
Investment in Africa over the past year with regard to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequencing has led to a massive increase in the number of sequences, which, to date, exceeds 100,000 sequences generated to track the pandemic on the continent. These sequences have profoundly affected how public health officials in Africa have navigated the COVID-19 pandemic.
RATIONALE
We demonstrate how the first 100,000 SARS-CoV-2 sequences from Africa have helped monitor the epidemic on the continent, how genomic surveillance expanded over the course of the pandemic, and how we adapted our sequencing methods to deal with an evolving virus. Finally, we also examine how viral lineages have spread across the continent in a phylogeographic framework to gain insights into the underlying temporal and spatial transmission dynamics for several variants of concern (VOCs).
RESULTS
Our results indicate that the number of countries in Africa that can sequence the virus within their own borders is growing and that this is coupled with a shorter turnaround time from the time of sampling to sequence submission. Ongoing evolution necessitated the continual updating of primer sets, and, as a result, eight primer sets were designed in tandem with viral evolution and used to ensure effective sequencing of the virus. The pandemic unfolded through multiple waves of infection that were each driven by distinct genetic lineages, with B.1-like ancestral strains associated with the first pandemic wave of infections in 2020. Successive waves on the continent were fueled by different VOCs, with Alpha and Beta cocirculating in distinct spatial patterns during the second wave and Delta and Omicron affecting the whole continent during the third and fourth waves, respectively. Phylogeographic reconstruction points toward distinct differences in viral importation and exportation patterns associated with the Alpha, Beta, Delta, and Omicron variants and subvariants, when considering both Africa versus the rest of the world and viral dissemination within the continent. Our epidemiological and phylogenetic inferences therefore underscore the heterogeneous nature of the pandemic on the continent and highlight key insights and challenges, for instance, recognizing the limitations of low testing proportions. We also highlight the early warning capacity that genomic surveillance in Africa has had for the rest of the world with the detection of new lineages and variants, the most recent being the characterization of various Omicron subvariants.
CONCLUSION
Sustained investment for diagnostics and genomic surveillance in Africa is needed as the virus continues to evolve. This is important not only to help combat SARS-CoV-2 on the continent but also because it can be used as a platform to help address the many emerging and reemerging infectious disease threats in Africa. In particular, capacity building for local sequencing within countries or within the continent should be prioritized because this is generally associated with shorter turnaround times, providing the most benefit to local public health authorities tasked with pandemic response and mitigation and allowing for the fastest reaction to localized outbreaks. These investments are crucial for pandemic preparedness and response and will serve the health of the continent well into the 21st century
Modélisation et distribution adaptatives de grandes scènes naturelles
Cette thèse traite de la modélisation et la diffusion de grandes scènes 3D naturelles. Nous visons à fournir des techniques pour permettre à des utilisateurs de naviguer à distance dans une scène 3D naturelle, tout en assurant la cohérence botanique et l'interactivité. Tout d'abord, nous fournissons une technique de compression multi-résolution, fondée sur la normalisation, l'instanciation, la décorrélation, et sur le codage entropique des informations ge ometriques pour des modèles de plantes. Ensuite, nous étudions la transmission efficace de ces objets 3D. L'algorithme de paquétisation proposé fonctionne pour la plupart des représentations multi-résolution d'objet 3D. Nous validons les techniques de paquétisation par des expériences sur un WAN (Wide Area Network), avec et sans contrôle de congestion (Datagram Congestion Control Protocol). Enfin, nous abordons les questions du streaming au niveau de la scène. Nous optimisons le traitement des requêtes du côté serveur en fournissant une structure de données adaptée et nous préparons le terrain pour nos travaux futurs sur l'évolutivité et le déploiement de systèmes distribués de streaming 3D.This thesis deals with the modeling and the interactive streaming of large natural 3D scenes. We aim at providing techniques to allow the remote walkthrough of users in a natural 3D scene ensuring botanical coherency and interactivity.First, we provide a compact and progressive representation for botanically realistic plant models. The topological structure and the geometry of the plants are represented by generalized cylinders. We provide a multi-resolution compression scheme, based on standardization and instantiation, on difference-based decorrelation, and on entropy coding. Then, we study efficient transmission of these 3D objects. The proposed packetization scheme works for any multi-resolution 3D representation. We validate our packetization schemes with extensive experiments over a WAN (Wide Area Network), with and without congestion control (Datagram Congestion Control Protocol). Finally, we address issues on streaming at the scene-level. We optimize the viewpoint culling requests on server-side by providing an adapted datastructure and we prepare the ground for our further work on scalability and deployment of distributed 3D streaming systems.TOULOUSE-INP (315552154) / SudocSudocFranceF
Approximations simples d'intégrales de chemins à température finie
LYON-ENS Sciences (693872304) / SudocSudocFranceF
Hierarchically constrained blackbox optimization
In blackbox optimization, evaluation of the objective and constraint
functions is time consuming. In some situations, constraint values may be
evaluated independently or sequentially. The present work proposes and compares
two strategies to define a hierarchical ordering of the constraints and to
interrupt the evaluation process at a trial point when it is detected that it
will not improve the current best solution. Numerical experiments are performed
on a closed-form test problem
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