Biochemical Evaluation of Cotton Genotypes using Soluble Protein, Esterase (EST), Peroxidase (POX) And Polyphenol Oxidase (PPO) and their Role in Plant Disease Resistance

Isozyme analysis is a powerful biochemical technique that has numerous applications in plant biology. It has long been used by geneticists to study the population genetics.  The isozyme esterase, peroxidase and polyphenol oxidase were standardized for upland cotton (Gossypium hirsutum L.) germplasm lines collected from all over the country.  The knowledge of nature and magnitude of genetic diversity present in the germplasm is most important pre-requisite for the success of any breeding program. The thirty-four cotton germplasm lines were screened for prime three isozymes based on quantification assay and qualitative PAGE profiling. Among the material, the genotype AKH – 24 (190.60 mg ml-1), AKH – 053 (189.42 mg ml-1) and VIKAS (184.53 mg ml-1) recorded high protein content, whereas the enzymatic activities of esterase, peroxidase and polyphenol oxidase exhibited remarkable differences along with the protein content. The genotype LRA–5166 exhibited high esterase (462.68 mM mg protein-1 min-1) and peroxidase activity (250.97mM mg protein-1 min-1), while AKH – 24 recorded the maximum polyphenol oxidase activity (131.45 mM mg protein-1min-1).  The banding pattern of biochemical markers revealed that the maximum number of bands were recorded in esterase analysis (fifteen) followed by protein (twelve) whereas, only five bands each were detected in peroxidase and polyphenol oxidase analysis indicating limited polymorphism.  The Relative Mobility (Rm) values were ranged from 0.083 to 0.883 (protein), 0.100 to 0.971 (esterase), 0.033 to 0.283 (peroxidase) and 0.048 to 0.206 (polyphenol oxidase).  The present study demonstrated that cotton genotypes could be differentiated by their quantity and quality through electrophoretic banding profiles. These results could be of practical value for cultivar identification, purity testing along with associated prediction of pest and disease resistance.  However, the major constraint is that these biochemical markers do not able to reproduce the similar kind of variation pattern, but can provide strong distinguishing polymorphism each time

Impact of Innovations in Value Chain on Sorghum Farmers

The paper has studied the implementation of millets value chain pilot project under the NAIP to create demand for sorghum through diversification in farm production, procurement, ultimately aiming at economical benefits to both farmers and other stakeholders. This 4.5 years novel initiative is still in the mid-way. The study has reported that technological backstopping of sorghum cultivation with end-product specific improved cultivars has realized 51 per cent rise in incremental net income of Rs 16098/ha for the participating farmers (58 per cent rise in kharif and 44 per cent in rabi farmers). The inconvenience in the preparation of sorghum foods which has been the important reason for the decrease in its consumption, has been eliminated through development of convenient and ready-to-eat/cook foods. The factorization of the investment expenditure made per farmer (one acre of sorghum per participating farmer) has been worked out to be Rs 356 (equivalent of Rs 890/ha) in a season resulting in 51 per cent rise in incremental net income over baseline which is slightly higher in kharif sorghum than in rabi sorghum. The output pricing in kharif has helped in attaining these benefits. However, the benefit-cost ratio has worked out in favour of rabi sorghum farmers, i.e. 1:7.5 vis-à-vis kharif farmers BC ratio of 1: 4.2. The study has observed that linking up of the entire stakeholders through value addition throughout the value chain system would renew and uplift the diminishing sorghum area and production and its ultimate economical benefits to farmers and other stakeholders in the value chain.Agricultural and Food Policy,

CIP System for Dairy Industry using PLC and SCADA

In few years ago CIP automation system used in dairy industry for cleaning purpose of tanks, pipes dairy equipment etc. but present automation system is design for cleaning purpose of milk tanker. Generally milk tanker is filled with pasteurized milk and this milk is transport form one place to another place durining transporting interior surface of tanker become oily and this oily part is remove by different cleaning method such as hot water process, caustic soda process and cold water process when cleaning operation carried out more litters water is wastage and this wastage water of tanker is provided to drainage or farm so there is very harmful for farm after few years. At that time more energy is required for cleaning operation. This situation are occurs in dairy industry so we have design a new automation system which is more helpful for cleaning process of tanker. This system is easy to operate, economical affordable, save energy and resources

Global surveillance of cancer survival 1995-2009: analysis of individual data for 25,676,887 patients from 279 population-based registries in 67 countries (CONCORD-2)

BACKGROUND: Worldwide data for cancer survival are scarce. We aimed to initiate worldwide surveillance of cancer survival by central analysis of population-based registry data, as a metric of the effectiveness of health systems, and to inform global policy on cancer control. METHODS: Individual tumour records were submitted by 279 population-based cancer registries in 67 countries for 25·7 million adults (age 15-99 years) and 75,000 children (age 0-14 years) diagnosed with cancer during 1995-2009 and followed up to Dec 31, 2009, or later. We looked at cancers of the stomach, colon, rectum, liver, lung, breast (women), cervix, ovary, and prostate in adults, and adult and childhood leukaemia. Standardised quality control procedures were applied; errors were corrected by the registry concerned. We estimated 5-year net survival, adjusted for background mortality in every country or region by age (single year), sex, and calendar year, and by race or ethnic origin in some countries. Estimates were age-standardised with the International Cancer Survival Standard weights. FINDINGS: 5-year survival from colon, rectal, and breast cancers has increased steadily in most developed countries. For patients diagnosed during 2005-09, survival for colon and rectal cancer reached 60% or more in 22 countries around the world; for breast cancer, 5-year survival rose to 85% or higher in 17 countries worldwide. Liver and lung cancer remain lethal in all nations: for both cancers, 5-year survival is below 20% everywhere in Europe, in the range 15-19% in North America, and as low as 7-9% in Mongolia and Thailand. Striking rises in 5-year survival from prostate cancer have occurred in many countries: survival rose by 10-20% between 1995-99 and 2005-09 in 22 countries in South America, Asia, and Europe, but survival still varies widely around the world, from less than 60% in Bulgaria and Thailand to 95% or more in Brazil, Puerto Rico, and the USA. For cervical cancer, national estimates of 5-year survival range from less than 50% to more than 70%; regional variations are much wider, and improvements between 1995-99 and 2005-09 have generally been slight. For women diagnosed with ovarian cancer in 2005-09, 5-year survival was 40% or higher only in Ecuador, the USA, and 17 countries in Asia and Europe. 5-year survival for stomach cancer in 2005-09 was high (54-58%) in Japan and South Korea, compared with less than 40% in other countries. By contrast, 5-year survival from adult leukaemia in Japan and South Korea (18-23%) is lower than in most other countries. 5-year survival from childhood acute lymphoblastic leukaemia is less than 60% in several countries, but as high as 90% in Canada and four European countries, which suggests major deficiencies in the management of a largely curable disease. INTERPRETATION: International comparison of survival trends reveals very wide differences that are likely to be attributable to differences in access to early diagnosis and optimum treatment. Continuous worldwide surveillance of cancer survival should become an indispensable source of information for cancer patients and researchers and a stimulus for politicians to improve health policy and health-care systems

Search for gravitational waves from Scorpius X-1 in the second Advanced LIGO observing run with an improved hidden Markov model

We present results from a semicoherent search for continuous gravitational waves from the low-mass x-ray binary Scorpius X-1, using a hidden Markov model (HMM) to track spin wandering. This search improves on previous HMM-based searches of LIGO data by using an improved frequency domain matched filter, the J-statistic, and by analyzing data from Advanced LIGO's second observing run. In the frequency range searched, from 60 to 650 Hz, we find no evidence of gravitational radiation. At 194.6 Hz, the most sensitive search frequency, we report an upper limit on gravitational wave strain (at 95% confidence) of h095%=3.47×10-25 when marginalizing over source inclination angle. This is the most sensitive search for Scorpius X-1, to date, that is specifically designed to be robust in the presence of spin wandering. © 2019 American Physical Society

Search for Tensor, Vector, and Scalar Polarizations in the Stochastic Gravitational-Wave Background

The detection of gravitational waves with Advanced LIGO and Advanced Virgo has enabled novel tests of general relativity, including direct study of the polarization of gravitational waves. While general relativity allows for only two tensor gravitational-wave polarizations, general metric theories can additionally predict two vector and two scalar polarizations. The polarization of gravitational waves is encoded in the spectral shape of the stochastic gravitational-wave background, formed by the superposition of cosmological and individually unresolved astrophysical sources. Using data recorded by Advanced LIGO during its first observing run, we search for a stochastic background of generically polarized gravitational waves. We find no evidence for a background of any polarization, and place the first direct bounds on the contributions of vector and scalar polarizations to the stochastic background. Under log-uniform priors for the energy in each polarization, we limit the energy densities of tensor, vector, and scalar modes at 95% credibility to Ω0T<5.58×10-8, Ω0V<6.35×10-8, and Ω0S<1.08×10-7 at a reference frequency f0=25 Hz. © 2018 American Physical Society

Erratum: "A Gravitational-wave Measurement of the Hubble Constant Following the Second Observing Run of Advanced LIGO and Virgo" (2021, ApJ, 909, 218)

[no abstract available

On the progenitor of binary neutron star merger GW170817

On 2017 August 17 the merger of two compact objects with masses consistent with two neutron stars was discovered through gravitational-wave (GW170817), gamma-ray (GRB 170817A), and optical (SSS17a/AT 2017gfo) observations. The optical source was associated with the early-type galaxy NGC 4993 at a distance of just ∼40 Mpc, consistent with the gravitational-wave measurement, and the merger was localized to be at a projected distance of ∼2 kpc away from the galaxy's center. We use this minimal set of facts and the mass posteriors of the two neutron stars to derive the first constraints on the progenitor of GW170817 at the time of the second supernova (SN). We generate simulated progenitor populations and follow the three-dimensional kinematic evolution from binary neutron star (BNS) birth to the merger time, accounting for pre-SN galactic motion, for considerably different input distributions of the progenitor mass, pre-SN semimajor axis, and SN-kick velocity. Though not considerably tight, we find these constraints to be comparable to those for Galactic BNS progenitors. The derived constraints are very strongly influenced by the requirement of keeping the binary bound after the second SN and having the merger occur relatively close to the center of the galaxy. These constraints are insensitive to the galaxy's star formation history, provided the stellar populations are older than 1 Gyr