On thermal nucleation of quark matter in compact stars

The possibility of a hadron-quark phase transition in extreme astrophysical phenomena such as the collapse of a supernova is not discarded by the modern knowledge of the high-energy nuclear and quark-matter equations of state. Both the density and the temperature attainable in such extreme processes are possibly high enough to trigger a chiral phase transition. However, the time scales involved are an important issue. Even if the physical conditions for the phase transition are favorable (for a system in equilibrium), there may not be enough time for the dynamical process of phase conversion to be completed. We analyze the relevant time scales for the phase conversion via thermal nucleation of bubbles of quark matter and compare them to the typical astrophysical time scale, in order to verify the feasibility of the scenario of hadron-quark phase conversion during, for example, the core-collapse of a supernova.Comment: 6 pages, 4 figures, talk given at the International Conference SQM2009, Buzios, Rio de Janeiro, Brazil, Sep.27-Oct.2, 200

Local characterization of hindered Brownian motion by using digital video microscopy and 3D particle tracking

This is the author accepted manuscript. The final version is available from the publisher via the DOI in this record.In this article we present methods for measuring hindered Brownian motion in the confinement of complex 3D geometries using digital video microscopy. Here we discuss essential features of automated 3D particle tracking as well as diffusion data analysis. By introducing local mean squared displacement-vs-time curves, we are able to simultaneously measure the spatial dependence of diffusion coefficients, tracking accuracies and drift velocities. Such local measurements allow a more detailed and appropriate description of strongly heterogeneous systems as opposed to global measurements. Finite size effects of the tracking region on measuring mean squared displacements are also discussed. The use of these methods was crucial for the measurement of the diffusive behavior of spherical polystyrene particles (505 nm diameter) in a microfluidic chip. The particles explored an array of parallel channels with different cross sections as well as the bulk reservoirs. For this experiment we present the measurement of local tracking accuracies in all three axial directions as well as the diffusivity parallel to the channel axis while we observed no significant flow but purely Brownian motion. Finally, the presented algorithm is suitable also for tracking of fluorescently labeled particles and particles driven by an external force, e.g., electrokinetic or dielectrophoretic forces.S.L.D. acknowledges funding from the German Academic Exchange Service (DAAD) and the German National Academic Foundation. S.P. and U.F.K. were supported by an ERC starting grant. S.P. also acknowledges the support from the Leverhulme Trust and the Newton Trust through an Early Career Fellowship

Channel-facilitated diffusion boosted by particle binding at the channel entrance

This is the final version of the article. Available from the publisher via the DOI in this record.We investigate single-file diffusion of Brownian particles in arrays of closely confining microchannels permeated by a variety of attractive optical potentials and connecting two baths with equal particle concentration. We simultaneously test free diffusion in the channel, diffusion in optical traps coupled in the center of the channel, and diffusion in traps extending into the baths. We found that both classes of attractive optical potentials enhance the translocation rate through the channel with respect to free diffusion. Surprisingly, for the latter class of potentials we measure a 40-fold enhancement in the translocation rate with respect to free diffusion and find a sublinear power law dependence of the translocation rate on the average number of particles in the channel. Our results reveal the function of particle binding at the channel entrances for diffusive transport and open the way to a better understanding of membrane transport and design of synthetic membranes with enhanced diffusion rate.S. P. acknowledges support from the Leverhulme and Newton Trust through an Early Career Fellowship. S. L. D. acknowledges funding from the German Academic Exchange Service (DAAD) and the German National Academic Foundation. U. F. K. was supported by an ERC starting grant

MMHelper: An automated framework for the analysis of microscopy images acquired with the mother machine

This is the final version. Available from Nature Research via the DOI in this record.Live-cell imaging in microfluidic devices now allows the investigation of cellular heterogeneity within microbial populations. In particular, the mother machine technology developed by Wang et al. has been widely employed to investigate single-cell physiological parameters including gene expression, growth rate, mutagenesis, and response to antibiotics. One of the advantages of the mother machine technology is the ability to generate vast amounts of images; however, the time consuming analysis of these images constitutes a severe bottleneck. Here we overcome this limitation by introducing MMHelper (https://doi.org/10.5281/zenodo.3254394), a publicly available custom software implemented in Python which allows the automated analysis of brightfield or phase contrast, and any associated fluorescence, images of bacteria confined in the mother machine. We show that cell data extracted via MMHelper from tens of thousands of individual cells imaged in brightfield are consistent with results obtained via semi-automated image analysis based on ImageJ. Furthermore, we benchmark our software capability in processing phase contrast images from other laboratories against other publicly available software. We demonstrate that MMHelper has over 90% detection efficiency for brightfield and phase contrast images and provides a new open-source platform for the extraction of single-bacterium data, including cell length, area, and fluorescence intensity.Royal SocietyWellcome TrustMRCBBSR

Scour features at wood bundles

Structures like blunt-nosed chevrons, log deflectors and double-winged log frames help in modifying the flow regime in the channel by concentrating the flow and increasing navigability. Moreover, they create scour pools in the downstream stilling basin, which can be used either as fish refuge or as an in-stream storage site for previously dredged material. In this respect, the use of wood debris in the channel in the form of wood bundles has gained attention for the ability of these structures to integrate into the surrounding fluvial habitat and to divert the flow partially towards the central part of the channel when placed in curves. Considering the absence of studies dealing with wood bundles as a restoration structure, the aim of this paper is to analyse the scour mechanism and equilibrium scour morphology of wood bundles in straight and curved channels. In doing so, a wide range of hydraulic conditions, structure positions and configurations were tested. Thereafter, dimensional analysis was carried out to derive useful empirical relationships to predict the maximum scour depth and length as well as the maximum dune height based on a novel, equivalent Froude number, which accounts for the effects of channel curvature and structure position. Moreover, the various resulting scour morphology types were classified, and conditions of their existence were determined depending on the abovementioned Froude number and other key hydraulic parameters

Anisotropic diffusion of spherical particles in closely confining microchannels

This is the author accepted manuscript. The final version is available from the publisher via the DOI in this record.We present here the measurement of the diffusivity of spherical particles closely confined by narrow microchannels. Our experiments yield a two-dimensional map of the position-dependent diffusion coefficients parallel and perpendicular to the channel axis with a resolution down to 129 nm. The diffusivity was measured simultaneously in the channel interior, the bulk reservoirs, as well as the channel entrance region. In the channel interior we found strongly anisotropic diffusion. While the perpendicular diffusion coefficient close to the confining walls decreased down to approximately 25% of the value on the channel axis, the parallel diffusion coefficient remained constant throughout the entire channel width. In addition to the experiment, we performed finite element simulations for the diffusivity in the channel interior and found good agreement with the measurements. Our results reveal the distinctive influence of strong confinement on Brownian motion, which is of significance to microfluidics as well as quantitative models of facilitated membrane transport.S.L.D. acknowledges funding from the German Academic Exchange Service (DAAD) and the German National Academic Foundation. S.P. and U.F.K. were supported by an ERC starting grant. S.P. also acknowledges support from the Leverhulme Trust and the Newton Trust through an Early Career Fellowship

A Critical Analysis of Jet-Induced Scour Formulas

Many studies investigate erosive processes occurring in non-cohesive granular materials downstream of grade-control structures, dam spillways, headcuts, and other hydraulic structures. Because of the complexity of the scour mechanism, the analysis of the scour phenomenon caused by plunging jets is generally conducted by using physical models and particularly for specific structure geometries. In this regard, many researchers proposed empirical approaches to estimate the main scour lengths, but their contributions are limited to tested conditions and cannot be generalized. This lack of generality has been (partially) overcome by other, more recent, approaches, that are either semitheoretical or fully theoretical. Previous works assessed the predictive capability of the most well-known empirical relationships but did not present a comparative analysis between empirical and (semi- )theoretical relationships. The aim of this paper is to contribute to fill this gap of knowledge. Namely, we present an experimental validation of the most popular relationships using a large database. In addition, we compare the predictive capability of some (semi-)theoretical relationships with that of the best known empirical formulas. In doing so, we provide interesting insights into the different approaches, highlighting their limits in assessing the main scour features. Overall, this paper provides a critical and updated analysis of different approaches for scour problems caused by plunging jets

Nucleation of quark matter in protoneutron star matter

The phase transition from hadronic to quark matter may take place already during the early post-bounce stage of core collapse supernovae when matter is still hot and lepton rich. If the phase transition is of first order and exhibits a barrier, the formation of the new phase occurs via the nucleation of droplets. We investigate the thermal nucleation of a quark phase in supernova matter and calculate its rate for a wide range of physical parameters. We show that the formation of the first droplet of a quark phase might be very fast and therefore the phase transition to quark matter could play an important role in the mechanism and dynamics of supernova explosions.Comment: v3: fits version published in Physical Review

Reflectance and photoluminescence characterization of CdS and CdSe heteroepitaxial films deposited by laser ablation technique

Optical properties of CdSe and CdS films, deposited on sapphire substrate by means of pulsed laser ablation technique, have been investigated in order to study the effect of such a transparent substrate on the photoluminescence efficiency of the deposited epilayers. CdSe and CdS films present intrinsic (excitonic) emission at low temperature, differently from the same films deposited on quartz. The temperature dependence of the excitonic energy has been analyzed taking into account the contribution of both the thermal dilatation and electron-phonon interaction