222 research outputs found
Asymmetric dearomative spirolactonization of naphthols using λ 3 -iodanes under chiral phase-transfer catalysis
The asymmetric phase-transfer catalytic effect of chiral Cinchona alkaloid-derived quaternary ammonium salts was investigated in the context of the λ3-iodane-mediated dearomative spirolactonization of naphthols. The scope and limitations of this methodology were evaluated using various substrates, which were converted into spirolactones in good yields and with enantiomeric excesses up to 58%
Effects of Trihalomethanes on Liver Mitochondria
Introduction: Trihalomethanes (THMs), namely dibromochloromethane
(DBCM) and bromodichloromethane (BDCM), are disinfection
byproducts of chlorinated water. This experiment aimed to
evaluate the mitochondrial dysfunction induced by THMs at low
levels in a mouse model
Transitions of cardio-metabolic risk factors in the Americas between 1980 and 2014
Describing the prevalence and trends of cardiometabolic risk factors that are associated with non-communicable diseases (NCDs) is crucial for monitoring progress, planning prevention, and providing evidence to support policy efforts. We aimed to analyse the transition in body-mass index (BMI), obesity, blood pressure, raised blood pressure, and diabetes in the Americas, between 1980 and 2014
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