611 research outputs found

    Smoking in pregnancy, adolescent mental health and cognitive performance in young adult offspring: results from a matched sample within a Finnish cohort

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    Background:\textbf{Background:} The association between prenatal exposure to maternal cigarette smoking (PEMCS) and adult cognition is debated, including if there are differences according to sex. We aimed to determine if there are associations between PEMCS and cognition in early adulthood in men and women and examine if observed associations were mediated by adolescent mental health factors that are associated with cognition, namely psychotic-like experiences (PLEs), inattention and hyperactivity, and other externalizing behaviors. Methods:\textbf{Methods:} Participants were 471 individuals drawn from the general population-based Northern Finland 1986 Birth Cohort (NFBC 1986) followed up from pregnancy and birth to early adulthood; individuals with PEMCS were matched with those without PEMCS by socioeconomic and demographic factors. Cognitive performance in adulthood was assessed with a range of tests and their association with PEMCS was measured by sex using hierarchical linear regression, unadjusted and then controlling for potential confounders, mediators and moderators, including adolescent mental health factors. Results:\textbf{Results:} There were no associations between PEMCS and cognitive scores in females. In males, there were associations with vocabulary (beta = -0.444, 95% CI: -0.783, -0.104) and matrix reasoning (beta = -0.379, 95% CI: -0.711, -0.047). Conclusions:\textbf{Conclusions:} While associations between PEMCS and cognition were limited, observed findings with measures of general intelligence in males contribute to suggestions of differences in response to PEMCS by sex. Furthermore, observed associations may be partly mediated by earlier inattention and hyperactivity. Findings add support to efforts aimed to eliminate smoking in pregnancy.The Northern Finland Birth Cohort 1986 is funded by the University of Oulu, University Hospital of Oulu, Academy of Finland, Sigrid Juselius Foundation, European Commission (EURO-BLCS, Framework 5 award QLG1-CT-2000- 01643), and NIH/NIMH (5R01MH63706:02). Cambridge Cognition Ltd. provided support in the form of salaries for author Jennifer H. Barnett

    Theory of Incompressible States in a Narrow Channel

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    We report on the properties of a system of interacting electrons in a narrow channel in the quantum Hall effect regime. It is shown that an increase in the strength of the Coulomb interaction causes abrupt changes in the width of the charge-density profile of translationally invariant states. We derive a phase diagram which includes many of the stable odd-denominator states as well as a novel fractional quantum Hall state at lowest half-filled Landau level. The collective mode evaluated at the half-filled case is strikingly similar to that for an odd-denominator fractional quantum Hall state.Comment: 4 pages, REVTEX, and 4 .ps file

    Persistent Currents in Small, Imperfect Hubbard Rings

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    We have done a study with small, imperfect Hubbard rings with exact diagonalization. The results for few-electron rings show, that the imperfection, whether localized or not, nearly always decrease, but can also \emph{increase} the persistent current, depending on the character of the imperfection and the on-site interaction. The calculations are generally in agreement with more specialized studies. In most cases the electron spin plays an important role.Comment: 6 pages, 4 figure

    The DLV System for Knowledge Representation and Reasoning

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    This paper presents the DLV system, which is widely considered the state-of-the-art implementation of disjunctive logic programming, and addresses several aspects. As for problem solving, we provide a formal definition of its kernel language, function-free disjunctive logic programs (also known as disjunctive datalog), extended by weak constraints, which are a powerful tool to express optimization problems. We then illustrate the usage of DLV as a tool for knowledge representation and reasoning, describing a new declarative programming methodology which allows one to encode complex problems (up to Δ3P\Delta^P_3-complete problems) in a declarative fashion. On the foundational side, we provide a detailed analysis of the computational complexity of the language of DLV, and by deriving new complexity results we chart a complete picture of the complexity of this language and important fragments thereof. Furthermore, we illustrate the general architecture of the DLV system which has been influenced by these results. As for applications, we overview application front-ends which have been developed on top of DLV to solve specific knowledge representation tasks, and we briefly describe the main international projects investigating the potential of the system for industrial exploitation. Finally, we report about thorough experimentation and benchmarking, which has been carried out to assess the efficiency of the system. The experimental results confirm the solidity of DLV and highlight its potential for emerging application areas like knowledge management and information integration.Comment: 56 pages, 9 figures, 6 table

    The Dynamics of Ecosystems, Biodiversity Management and Social Institutions at High Northern Latitudes

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    Ecosystems at high latitudes are highly dynamic, influenced by a multitude of large-scale disturbances. Due to global change processes these systems may be expected to be particularly vulnerable, affecting the sustained production of renewable wood resources and abundance of plants and animals on which local cultures depend. In this paper, we assess the implications of new understandings of high northern latitude ecosystems and what must be done to manage systems for resilience. We suggest that the focus of land management should shift from recovery from local disturbance to sustaining ecosystem functions in the face of change and disruption. The role of biodiversity as insurance for allowing a system to reorganize and develop during the disturbance and reorganization phases needs to be addressed in management and policy. We emphasize that the current concepts of ecological reserves and protected areas need to be reconsidered to developp dynamic tools for sustainable management of ecosystems in face of change. Characteristics of what may be considered as customary reserves at high latitudes are often consistent with a more dynamic view of reserves. We suggest new directions for addressing biodiversity management in dynamic landscapes at high latitudes, and provide empirical examples of insights from unconventional perspectives that may help improve the potential for sustainable management of biodiversity and the generation of ecosystem services

    Quantifying the Detrimental Impacts of Land-Use and Management Change on European Forest Bird Populations

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    The ecological impacts of changing forest management practices in Europe are poorly understood despite European forests being highly managed. Furthermore, the effects of potential drivers of forest biodiversity decline are rarely considered in concert, thus limiting effective conservation or sustainable forest management. We present a trait-based framework that we use to assess the detrimental impact of multiple land-use and management changes in forests on bird populations across Europe. Major changes to forest habitats occurring in recent decades, and their impact on resource availability for birds were identified. Risk associated with these changes for 52 species of forest birds, defined as the proportion of each species' key resources detrimentally affected through changes in abundance and/or availability, was quantified and compared to their pan-European population growth rates between 1980 and 2009. Relationships between risk and population growth were found to be significantly negative, indicating that resource loss in European forests is an important driver of decline for both resident and migrant birds. Our results demonstrate that coarse quantification of resource use and ecological change can be valuable in understanding causes of biodiversity decline, and thus in informing conservation strategy and policy. Such an approach has good potential to be extended for predictive use in assessing the impact of possible future changes to forest management and to develop more precise indicators of forest health

    Current-spin-density functional study of persistent currents in quantum rings

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    We present a numerical study of persistent currents in quantum rings using current spin density functional theory (CSDFT). This formalism allows for a systematic study of the joint effects of both spin, interactions and impurities for realistic systems. It is illustrated that CSDFT is suitable for describing the physical effects related to Aharonov-Bohm phases by comparing energy spectra of impurity-free rings to existing exact diagonalization and experimental results. Further, we examine the effects of a symmetry-breaking impurity potential on the density and current characteristics of the system and propose that narrowing the confining potential at fixed impurity potential will suppress the persistent current in a characteristic way.Comment: 7 pages REVTeX, including 8 postscript figure
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