The application of a numerical integration procedure developed by erwin fehlberg to the restricted problem of three bodies

Application of numerical integration procedures to restricted three-body proble

Estimation of Parameters in DNA Mixture Analysis

In Cowell et al. (2007), a Bayesian network for analysis of mixed traces of DNA was presented using gamma distributions for modelling peak sizes in the electropherogram. It was demonstrated that the analysis was sensitive to the choice of a variance factor and hence this should be adapted to any new trace analysed. In the present paper we discuss how the variance parameter can be estimated by maximum likelihood to achieve this. The unknown proportions of DNA from each contributor can similarly be estimated by maximum likelihood jointly with the variance parameter. Furthermore we discuss how to incorporate prior knowledge about the parameters in a Bayesian analysis. The proposed estimation methods are illustrated through a few examples of applications for calculating evidential value in casework and for mixture deconvolution

Surface and electronic structure of MOCVD-grown Ga(0.92)In(0.08)N investigated by UV and X-ray photoelectron spectroscopies

The surface and electronic structure of MOCVD-grown layers of Ga(0.92)In(0.08)N have been investigated by means of photoemission. An additional feature at the valence band edge, which can be ascribed to the presence of In in the layer, has been revealed. A clean (0001)-(1x1) surface was prepared by argon ion sputtering and annealing. Stability of chemical composition of the investigated surface subjected to similar ion etching was proven by means of X-ray photoemission spectroscopy.Comment: 13 pages, 6 figure

HIGH PRESSURE FREEZE-OUT OF ELECTRONS IN UNDOPED GaN CRYSTAL. PROOF OF EXISTENCE OF RESONANT DONOR STATE (NITROGEN VACANCY)

We investigated free carriers related opticał absorption in GaN in hydrostatic pressures up to 30 GPa. The disappearance of this absorption at pressures close to 18 GPa was explained by trapping electrons resulting from the shift of nitrogen vacancy related donor level into the GaN energy gap at high pressure. We estimated the energetic position of this level at atmospheric pressure to be about 0.8 eV above the conduction band minimum

Electronic dielectric constants of insulators by the polarization method

We discuss a non-perturbative, technically straightforward, easy-to-use, and computationally affordable method, based on polarization theory, for the calculation of the electronic dielectric constant of insulating solids at the first principles level. We apply the method to GaAs, AlAs, InN, SiC, ZnO, GaN, AlN, BeO, LiF, PbTiO$_3$, and CaTiO$_3$. The predicted \einf's agree well with those given by Density Functional Perturbation Theory (the reference theoretical treatment), and they are generally within less than 10 % of experiment.Comment: RevTeX 4 pages, 2 ps figure

Microscopic modelling of doped manganites

Colossal magneto-resistance manganites are characterised by a complex interplay of charge, spin, orbital and lattice degrees of freedom. Formulating microscopic models for these compounds aims at meeting to conflicting objectives: sufficient simplification without excessive restrictions on the phase space. We give a detailed introduction to the electronic structure of manganites and derive a microscopic model for their low energy physics. Focussing on short range electron-lattice and spin-orbital correlations we supplement the modelling with numerical simulations.Comment: 20 pages, 10 figs, accepted for publ. in New J. Phys., Focus issue on Orbital Physic

СИМУЛЬТАННАЯ РЕТРОПЕРИТОНЕОСКОПИЧЕСКАЯ ДОНОРСКАЯ НЕФРЭКТОМИЯ С ХОЛЕЦИСТЭКТОМИЕЙ

The shortage of donor organs leads to a gradual extension of the selection criteria for living donors including age and presence of comorbidities. Performing simultaneous operations with donor nephrectomy would further increase the number of living donors and increase the attractiveness of operations. In this observation, the examination of a 60-year-old potential donor revealed a concomitant disease: chronic calculous cholecystitis, which had existed for over 20 years. Ultrasound examination of the abdomen showed a strong adhesion of the bowel to the anterior abdominal wall. To prevent the risk of damage to the abdominal organs, it was decided to perform the nephrectomy retroperitoneoscopically and a simultaneous cholecystectomy from the same access. This procedure has three major advantages: no contact with the abdominal cavity when performing the access, the easiest access to the renal arteries, and the absence of a systematic increase in intraperitoneal pressure. Such access is of particular importance for the patients who have had previous interventions on the abdominal organs. Нехватка донорских органов приводит к постепенному расширению критериев отбора живых доноров, включая возраст и наличие сопутствующих заболеваний. Выполнение симультанных операций с донорской нефрэктомией позволило бы дополнительно увеличить пул живых доноров, а также повысить привлекательность операций. В данном наблюдении при обследовании потенциального донора 60 лет обратило на себя внимание сопутствующее заболевание: хронический калькулезный холецистит, протекающий с многочисленными обострениями на протяжении более 20 лет. При ультразвуковом исследовании органов брюшной полости отмечена выраженная адгезия кишечника к передней брюшной стенке. С целью предотвращения риска повреждения органов брюшной полости было принято решение о выполнении нефрэктомии ретроперитонеоскопическим доступом и симультанной холецистэктомии из того же доступа. Операция имеет три основных преимущества: отсутствие контакта с органами брюшной полости при осуществлении доступа, наиболее простой доступ к почечным артериям, отсутствие системного повышения внутрибрюшинного давления. Такой доступ приобретает особое значение для пациентов, перенесших ранее вмешательства на органах брюшной полости.

ФУНКЦИОНАЛЬНЫЕ РЕЗУЛЬТАТЫ ИНТРАФАСЦИАЛЬНОЙ ЭНДОСКОПИЧЕСКОЙ ЭКСТРАПЕРИТОНЕАЛЬНОЙ РАДИКАЛЬНОЙ ПРОСТАТЭКТОМИИ

Introduction. Endoscopic radical prostatectomy is a highly effective treatment for localized prostate cancer. Intrafascial prostate dissection ensures early recovery of urine continence function and erectile function. This article sums up our own experience of performing intrafascial endoscopic prostatectomy.Materials and methods. 25 patients have undergone this procedure. 12 months after surgery 88.2 % of the patients were fully continent, 11.7 % had symptoms of minimal stress urinary incontinence. We encountered no cases of positive surgical margins and one case of bio-chemical recurrence of the disease.Conclusion. Oncologically, intrafascial endoscopic radical prostatectomy is as effective as other modifications of radical prostatectomy and has the benefits of early recovery of urine continence function and erectile function. Введение. Эндоскопическая радикальная простатэктомия является высокоэффективным методом лечения локализованного рака предстательной железы. Применение интрафасциального метода диссекции предстательной железы способствует раннему вос-становлению функции удержания мочи и эректильной функции. В статье приведен собственный опыт выполнения интрафасциальной эндоскопической простатэктомии.Материалы и методы. По данной методике прооперировано 25 пациентов. Через 12 мес после операции полная континенция достигнута у 88,2 % пациентов, 11,7 % пациентов имели признаки минимального стрессового недержания мочи. Положительного хирургического края не отмечено, биохимический рецидив развился у 1 пациента.Заключение. Онкологические результаты интрафасциальной эндоскопической простатэктомии не уступают другим методам радикальной простатэктомии, отмечено раннее восстановление континенции и эректильной функции

Опухолевые маркеры при скрининге и мониторинге больных раком мочевого пузыря

The study was undertaken to evaluate the specificity and sensitivity of a rapid method for qualitative determination of the content of NMP 22 in the diagnosis of cancer of the bladder, as well as the efficiency of the method in detecting recurrences of this disease.The method is based on enzyme immunoassay of the nuclear matrix proteins that are incorporated into the cell nuclear membrane, whose levels are approximately 20—80 times higher in the cancer cells of the bladder. The study included 83 patients. Group 1 comprised 18 patients with new-onset bladder cancer. Group 2 comprised 26 patients with histologically verified recurrent bladder cancer. Group 3 consisted of 19 patients who had a history of bladder cancer, received surgical treatment, and had no recurrences for at least 6 months. The control group included 20 healthy donors.The test urine was put into a test well and the results were assessed 30 minutes later.The resultant sensitivity of the test was 50% (p < 0.05) in the patients with new-onset cancer of the bladder and 54% (p < 0.05) in those with its recurrent cancer. With staging and grading of the disease and with higher tumor anaplasia, the sensitivity of the test increases: 37, 75, and 80% in T1, T2, T3, respectively (p < 0.05); 30, 50, and 87% in G1 (p > 0.05), G2 (p < 0.05), G3 (p < 0.05). Its specificity was 100% in Group 3 and 90% in the control group (p < 0.05). Thus, its total specificity was 95% (p < 0.05). The study has led to the conclusion that detection of NMP 22 is a promising marker of bladder carcinoma, which show a rather high specificity and specificity not only in identifying primary tumors, but a recurrence of the disease.