3,227 research outputs found
TechMiner: Extracting Technologies from Academic Publications
In recent years we have seen the emergence of a variety of scholarly datasets. Typically these capture âstandardâ scholarly entities and their connections, such as authors, affiliations, venues, publications, citations, and others. However, as the repositories grow and the technology improves, researchers are adding new entities to these repositories to develop a richer model of the scholarly domain. In this paper, we introduce TechMiner, a new approach, which combines NLP, machine learning and semantic technologies, for mining technologies from research publications and generating an OWL ontology describing their relationships with other research entities. The resulting knowledge base can support a number of tasks, such as: richer semantic search, which can exploit the technology dimension to support better retrieval of publications; richer expert search; monitoring the emergence and impact of new technologies, both within and across scientific fields; studying the scholarly dynamics associated with the emergence of new technologies; and others. TechMiner was evaluated on a manually annotated gold standard and the results indicate that it significantly outperforms alternative NLP approaches and that its semantic features improve performance significantly with respect to both recall and precision
The effects of metallicity and cooling physics on fragmentation: implications on direct-collapse black hole formation
A promising supermassive black hole seed formation channel is that of direct
collapse from primordial gas clouds. We perform a suite of 3D hydrodynamics
simulations of an isolated turbulent gas cloud to investigate conditions
conducive to forming massive black hole seeds via direct collapse, probing the
impact of cloud metallicity, gas temperature floor and cooling physics on cloud
fragmentation. We find there is no threshold in metallicity which produces a
sharp drop in fragmentation. When molecular cooling is not present, metallicity
has little effect on fragmentation. When molecular cooling is present,
fragmentation is suppressed by at most , with the greatest
suppression seen at metallicities below solar. A gas temperature floor
K produces the largest drop in fragmentation of any parameter
choice, reducing fragmentation by . At metallicities below
solar or at temperatures K we see a reduction in fragmentation
. For a cloud of metallicity solar above and a temperature
below K, the detailed choices of temperature floor, metallicity, and
cooling physics have little impact on fragmentation.Comment: 5 pages, 4 figures, submitted to MNRA
Ambiguity, multiple streams, and EU policy
The multiple streams framework draws insight from interactions between agency and institutions to explore the impact of context, time, and meaning on policy change and to assess the institutional and issue complexities permeating the European Union (EU) policy process. The authors specify the assumptions and structure of the framework and review studies that have adapted it to reflect more fully EU decision-making processes. The nature of policy entrepreneurship and policy windows are assessed to identify areas of improvement. Finally, the authors sketch out a research agenda that refines the logic of political manipulation which permeates the lens and the institutional complexity which frames the EU policy process
Comparative study of the biological behaviour in hamster of two isolates of leishmania characterized respectively as L. major-like and L. donovani
Hamster inoculated intraperitoneally with 1 x 10(7) parasites of L. donovani and L. major-like of the New World were studied in groups of 15, 30, 60 and 90 days of infection. The parasite load and density showed progressive increase with the evolution of the infection and was higher in the L. donovani groups than in the L. major-like groups. The L. major-like groups showed parasite density higher in the spleen than in the liver and was similar in both organs in L. donovani groups. The histopathology showed a diffuse marked hyperplasia and hypertrophy of the reticuloendothelial system with high parasitism in the L. donovani groups while there was focal involvement of these organs in L. major-like groups, forming nodules of macrophages that were scantly parasitised. The biological behaviour could be useful in the preliminary studies of Leishmania strain in regional laboratories and understanding the histopathology of lesions caused by different leishmania species.Experimentos utilizando-se hamsters inoculados intraperitonealmente com 1 x 10(7) parasitas de 2 cepas, L. donovani (MHOM/BR/72/LD 46) e L. major-like (MCAN/BR/73/LD 70) isoladas no Novo Mundo foram realizados e estudados em grupos de 15, 30, 60 e 90 dias de infecção. A carga e a densidade parasitĂĄria mostraram progressivo aumento com a evolução da infecção e foi maior nos grupos inoculados com L. donovani do que nos grupos inoculados com L. major-like. Os grupos inoculados com L. major-like mostraram densidade parasitĂĄria maior no baço que no fĂgado e foram semelhantes em ambos os ĂłrgĂŁos nos grupos inoculados com L. donovani. A histopatologia mostrou intensa e difusa hyperplasia e hipertrofia do sistema reticuloendotelial com alto parasitismo nos grupos inoculados com L. donovani, enquanto foi encontrado envolvimento focai nestes ĂłrgĂŁos nos grupos inoculados com L. major-like, formando nĂłdulos de macrĂłfagos discretamente parasitados. O comportamento biolĂłgico seria Ăștil em estudos preliminares de identificação de cepas de Leishmania em laboratĂłrios regionais e na compreensĂŁo da histopatologia das lesĂ”es causadas por diferentes espĂ©cimes de leishmanias
COLA II - Radio and Spectroscopic Diagnostics of Nuclear Activity in Galaxies
We present optical spectroscopic observations of 93 galaxies taken from the
infra-red selected COLA (Compact Objects in Low Power AGN) sample. The sample
spans the range of far-IR luminosities from normal galaxies to LIRGs. Of the
galaxies observed, 78 (84%) exhibit emission lines. Using a theoretically-based
optical emission-line scheme we classify 15% of the emission-line galaxies as
Seyferts, 77% as starbursts, and the rest are either borderline AGN/starburst
or show ambiguous characteristics. We find little evidence for an increase in
the fraction of AGN in the sample as a function of far-IR luminosity but our
sample covers only a small range in infrared luminosity and thus a weak trend
may be masked. As a whole the Seyfert galaxies exhibit a small, but
significant, radio excess on the radio-FIR correlation compared to the galaxies
classified as starbursts. Compact (<0.05'') radio cores are detected in 55% of
the Seyfert galaxies, and these galaxies exhibit a significantly larger radio
excess than the Seyfert galaxies in which cores were not detected. Our results
indicate that there may be two distinct populations of Seyferts,
``radio-excess'' Seyferts, which exhibit extended radio structures and compact
radio cores, and ``radio-quiet'' Seyferts, in which the majority of the radio
emission can be attributed to star-formation in the host galaxy. No significant
difference is seen between the IR and optical spectroscopic properties of
Seyferts with and without radio cores. (Abridged)Comment: 24 pages, 4 figures, 6 tables. Accepted for publication in ApJ,
February 200
Heterogeneity in the non-planarity and arterial curvature of arteriovenous fistulae in vivo
Objective: Native arteriovenous fistulae (AVF) for haemodialysis are susceptible to non-maturation. Adverse features of local blood flow have been implicated in the formation of peri-anastomotic neointimal hyperplasia which may underpin non-maturation. While computational fluid dynamic simulations of idealised models highlight the importance of geometry on fluid and vessel wall interactions, little is known in vivo about AVF geometry and its role in adverse clinical outcomes. This study set out to examine the three-dimensional geometry of native AVF and the geometric correlates of AVF failure. Methods: As part of an observational study between 2013 and 2016, patients underwent creation of an upper limb AVF according to current surgical best practice. Phase-contrast MRI was performed on the day of surgery to obtain luminal geometry along with ultrasound measurements of flow. MRI datasets were segmented and reconstructed for quantitative and qualitative analysis of local geometry. Clinical maturation was evaluated at six weeks. Results: 60 patients were successfully imaged on the day of surgery. Radiocephalic (n=17), brachiocephalic (n=40) and brachiobasilic (n=3) fistulae were all included in the study. Centrelines extracted from segmented vessel lumen exhibited significant heterogeneity in arterial non-planarity and curvature. Furthermore, these features are more marked in brachiocephalic as compared to radiocephalic fistulae. Across the cohort, the projected bifurcation angle was was 73° (±16°) mean (±sd). Geometry was preserved at two weeks in 20 patients who underwent repeat imaging. A greater degree of arterial non-planarity (log odds ratio (logOR) 0.95 per 0.1/vessel diameter (95% CI 0.22 to 1.90, P= .03)) along with a larger bifurcation angle (logOR 0.05 per degree (95% CI 0.01 to 0.09, P= .02)) are associated with a great rate of maturation, as is fistula location (upper vs lower arm) logOR -1.9 (95% CI -3.2 to 0.7, P = .002) . Conclusions: There is significant heterogeneity in the three-dimensional geometry of arteriovenous fistulae, in particular, arterial non-planarity and curvature. In this largest cohort of AVF geometry to date, the effect of individual geometric correlates on maturation is uncertain but supports the premise that future modelling studies will need to acknowledge the complex geometry of AVF
Reconfigurable Atomic Transaction Commit (Extended Version)
Modern data stores achieve scalability by partitioning data into shards and
fault-tolerance by replicating each shard across several servers. A key
component of such systems is a Transaction Certification Service (TCS), which
atomically commits a transaction spanning multiple shards. Existing TCS
protocols require 2f+1 crash-stop replicas per shard to tolerate f failures. In
this paper we present atomic commit protocols that require only f+1 replicas
and reconfigure the system upon failures using an external reconfiguration
service. We furthermore rigorously prove that these protocols correctly
implement a recently proposed TCS specification. We present protocols in two
different models--the standard asynchronous message-passing model and a model
with Remote Direct Memory Access (RDMA), which allows a machine to access the
memory of another machine over the network without involving the latter's CPU.
Our protocols are inspired by a recent FARM system for RDMA-based transaction
processing. Our work codifies the core ideas of FARM as distributed TCS
protocols, rigorously proves them correct and highlights the trade-offs
required by the use of RDMA.Comment: Extended version of the PODC' 19 paper: Reconfigurable Atomic
Transaction Commi
Ultraviolet and Multiwavelength Variability of the Blazar 3C 279: Evidence for Thermal Emission
The gamma-ray blazar 3C 279 was monitored on a nearly daily basis with IUE,
ROSAT and EGRET for three weeks between December 1992 and January 1993. During
this period, the blazar was at a historical minimum at all wavelengths. Here we
present the UV data obtained during the above multiwavelength campaign. A
maximum UV variation of ~50% is detected, while during the same period the
X-ray flux varied by no more than 13%. At the lowest UV flux level the average
spectrum in the 1230-2700 A interval is unusually flat for this object
(~1). The flattening could represent the lowest energy tail of the
inverse Compton component responsible for the X-ray emission, or could be due
to the presence of a thermal component at ~20000 K possibly associated with an
accretion disk. The presence of an accretion disk in this blazar object, likely
observable only in very low states and otherwise hidden by the beamed, variable
synchrotron component, would be consistent with the scenario in which the seed
photons for the inverse Compton mechanism producing the gamma-rays are external
to the relativistic jet. We further discuss the long term correlation of the UV
flux with the X-ray and gamma-ray fluxes obtained at various epochs. All UV
archival data are included in the analysis. Both the X- and gamma-ray fluxes
are generally well correlated with the UV flux, approximately with square root
and quadratic dependences, respectively.Comment: 22 pages, Latex, 7 PostScript figures, to appear in The Astrophysical
Journa
Pain assessment for people with dementia: a systematic review of systematic reviews of pain assessment tools.
BACKGROUND: There is evidence of under-detection and poor management of pain in patients with dementia, in both long-term and acute care. Accurate assessment of pain in people with dementia is challenging and pain assessment tools have received considerable attention over the years, with an increasing number of tools made available. Systematic reviews on the evidence of their validity and utility mostly compare different sets of tools. This review of systematic reviews analyses and summarises evidence concerning the psychometric properties and clinical utility of pain assessment tools in adults with dementia or cognitive impairment. METHODS: We searched for systematic reviews of pain assessment tools providing evidence of reliability, validity and clinical utility. Two reviewers independently assessed each review and extracted data from them, with a third reviewer mediating when consensus was not reached. Analysis of the data was carried out collaboratively. The reviews were synthesised using a narrative synthesis approach. RESULTS: We retrieved 441 potentially eligible reviews, 23 met the criteria for inclusion and 8 provided data for extraction. Each review evaluated between 8 and 13 tools, in aggregate providing evidence on a total of 28 tools. The quality of the reviews varied and the reporting often lacked sufficient methodological detail for quality assessment. The 28 tools appear to have been studied in a variety of settings and with varied types of patients. The reviews identified several methodological limitations across the original studies. The lack of a 'gold standard' significantly hinders the evaluation of tools' validity. Most importantly, the samples were small providing limited evidence for use of any of the tools across settings or populations. CONCLUSIONS: There are a considerable number of pain assessment tools available for use with the elderly cognitive impaired population. However there is limited evidence about their reliability, validity and clinical utility. On the basis of this review no one tool can be recommended given the existing evidence
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