Detection and prevention of financial abuse against elders

This article is made available through the Brunel Open Access Publishing Fund. Copyright @ The Authors. This article is published under the Creative Commons Attribution (CC BY 3.0) licence. Anyone may reproduce, distribute, translate and create derivative works of this article (for both commercial and non-commercial purposes), subject to full attribution to the original publication and authors. The full terms of this licence may be seen at http://creativecommons.org/licences/ by/3.0/legalcode.Purpose – This paper reports on banking and finance professionals' decision making in the context of elder financial abuse. The aim was to identify the case features that influence when abuse is identified and when action is taken. Design/methodology/approach – Banking and finance professionals (n=70) were shown 35 financial abuse case scenarios and were asked to judge how certain they were that the older person was being abused and the likelihood of taking action. Findings – Three case features significantly influenced certainty of financial abuse: the nature of the financial problem presented, the older person's level of mental capacity and who was in charge of the client's money. In cases where the older person was more confused and forgetful, there was increased suspicion that financial abuse was taking place. Finance professionals were less certain that financial abuse was occurring if the older person was in charge of his or her own finances. Originality/value – The research findings have been used to develop freely available online training resources to promote professionals' decision making capacity (www.elderfinancialabuse.co.uk). The resources have been advocated for use by Building Societies Association as well as CIFAS, the UK's Fraud Prevention Service.The research reported here was funded by the UK cross council New Dynamicsof Ageing Programme, ESRC Reference No. RES-352-25-0026, with Mary L.M. Gilhooly asPrincipal Investigator. Web-based training tools, developed from the research findings, weresubsequently funded by the ESRC follow-on fund ES/J001155/1 with Priscilla A. Harries asPrincipal Investigator

Modality, Potentiality and Contradiction in Quantum Mechanics

In [11], Newton da Costa together with the author of this paper argued in favor of the possibility to consider quantum superpositions in terms of a paraconsistent approach. We claimed that, even though most interpretations of quantum mechanics (QM) attempt to escape contradictions, there are many hints that indicate it could be worth while to engage in a research of this kind. Recently, Arenhart and Krause [1, 2, 3] have raised several arguments against this approach and claimed that, taking into account the square of opposition, quantum superpositions are better understood in terms of contrariety propositions rather than contradictory propositions. In [17] we defended the Paraconsistent Approach to Quantum Superpositions (PAQS) and provided arguments in favor of its development. In the present paper we attempt to analyze the meanings of modality, potentiality and contradiction in QM, and provide further arguments of why the PAQS is better suited, than the Contrariety Approach to Quantum Superpositions (CAQS) proposed by Arenhart and Krause, to face the interpretational questions that quantum technology is forcing us to consider.Comment: Published in: New Directions in Paraconsistent Logic, J-Y B\'eziau M. Chakraborty & S. Dutta (Eds.), Springer, in press. arXiv admin note: text overlap with arXiv:1404.518

Working memory and attention in choice.

We study the role of attention and working memory in choices where options are presented sequentially rather than simultaneously. We build a model where a costly attention effort is chosen, which can vary over time. Evidence is accumulated proportionally to this effort and the utility of the reward. Crucially, the evidence accumulated decays over time. Optimal attention allocation maximizes expected utility from final choice; the optimal solution takes the decay into account, so attention is preferentially devoted to later times; but convexity of the flow attention cost prevents it from being concentrated near the end. We test this model with a choice experiment where participants observe sequentially two options. In our data the option presented first is, everything else being equal, significantly less likely to be chosen. This recency effect has a natural explanation with appropriate parameter values in our model of leaky evidence accumulation, where the decline is stronger for the option observed first. Analysis of choice, response time and brain imaging data provide support for the model. Working memory plays an essential role. The recency bias is stronger for participants with weaker performance in working memory tasks. Also activity in parietal areas, coding the stored value in working, declines over time as predicted

Contextual logic for quantum systems

In this work we build a quantum logic that allows us to refer to physical magnitudes pertaining to different contexts from a fixed one without the contradictions with quantum mechanics expressed in no-go theorems. This logic arises from considering a sheaf over a topological space associated to the Boolean sublattices of the ortholattice of closed subspaces of the Hilbert space of the physical system. Differently to standard quantum logics, the contextual logic maintains a distributive lattice structure and a good definition of implication as a residue of the conjunction.Comment: 16 pages, no figure

The Circular Economy: What, Why, How and Where

This paper was prepared as a background document for an OECD/EC high-level expert workshop on “Managing the transition to a circular economy in regions and cities” held on 5 July 2019 at the OECD Headquarters in Paris, France. It sets a basis for reflection and discussion. The background paper should not be reported as representing the official views of the European Commission, the OECD or one of its member countries. The opinions expressed and arguments employed are those of the author(s)

A quantum logical and geometrical approach to the study of improper mixtures

We study improper mixtures from a quantum logical and geometrical point of view. Taking into account the fact that improper mixtures do not admit an ignorance interpretation and must be considered as states in their own right, we do not follow the standard approach which considers improper mixtures as measures over the algebra of projections. Instead of it, we use the convex set of states in order to construct a new lattice whose atoms are all physical states: pure states and improper mixtures. This is done in order to overcome one of the problems which appear in the standard quantum logical formalism, namely, that for a subsystem of a larger system in an entangled state, the conjunction of all actual properties of the subsystem does not yield its actual state. In fact, its state is an improper mixture and cannot be represented in the von Neumann lattice as a minimal property which determines all other properties as is the case for pure states or classical systems. The new lattice also contains all propositions of the von Neumann lattice. We argue that this extension expresses in an algebraic form the fact that -alike the classical case- quantum interactions produce non trivial correlations between the systems. Finally, we study the maps which can be defined between the extended lattice of a compound system and the lattices of its subsystems.Comment: submitted to the Journal of Mathematical Physic

Depletion of Mediator Kinase Module Subunits Represses Superenhancer-Associated Genes in Colon Cancer Cells

In cancer, oncogene activation is partly mediated by acquired superenhancers, which therefore represent potential targets for inhibition. Superenhancers are enriched for BRD4 and Mediator, and both BRD4 and the Mediator MED12 subunit are disproportionally required for expression of superenhancer-associated genes in stem cells. Here we show that depletion of Mediator kinase module subunit MED12 or MED13 together with MED13L can be used to reduce expression of cancer-acquired superenhancer genes, such as the MYC gene, in colon cancer cells, with a concomitant decrease in proliferation. Whereas depletion of MED12 or MED13/MED13L caused a disproportional decrease of superenhancer gene expression, this was not seen with depletion of the kinases cyclin-dependent kinase 9 (CDK8) and CDK19. MED12-MED13/MED13L-dependent superenhancer genes were coregulated by beta-catenin, which has previously been shown to associate with MED12. Importantly, beta-catenin depletion caused reduced binding of MED12 at the MYC superenhancer. The effect of MED12 or MED13/MED13L depletion on cancer-acquired superenhancer gene expression was more specific than and partially distinct from that of BRD4 depletion, with the most efficient inhibition seen with combined targeting. These results identify a requirement of MED12 and MED13/MED13L for expression of acquired superenhancer genes in colon cancer, implicating these Mediator subunits as potential therapeutic targets for colon cancer, alone or together with BRD4.Peer reviewe