Neuronal Distortions of Reward Probability without Choice

Reward probability crucially determines the value of outcomes. A basic phenomenon, defying explanation by traditional decision theories, is that people often overweigh small and underweigh large probabilities in choices under uncertainty. However, the neuronal basis of such reward probability distortions and their position in the decision process are largely unknown. We assessed individual probability distortions with behavioral pleasantness ratings and brain imaging in the absence of choice. Dorsolateral frontal cortex regions showed experience dependent overweighting of small, and underweighting of large, probabilities whereas ventral frontal regions showed the opposite pattern. These results demonstrate distorted neuronal coding of reward probabilities in the absence of choice, stress the importance of experience with probabilistic outcomes and contrast with linear probability coding in the striatum. Input of the distorted probability estimations to decision-making mechanisms are likely to contribute to well known inconsistencies in preferences formalized in theories of behavioral economics

The imaginary audience and the personal fable in relation to the separation-individuation process during adolescence

Lapsley’s (1993) “New Look” model for the interpretation of adolescent egocentrism, as an alternative to the classic cognitive one formulated by Elkind (1967), was tested in this study. According to the “New Look” model, the two manifestations of adolescent egocentrism – the imaginary audience and the personal fable – are adaptive coping mechanisms used by adolescents in their attempt to deal with the stressful developmental aim of separation-individuation. Two-hundred ninety seven adolescents 11-18 years’ old completed the Imaginary Audience Scale (Elkind & Bowen, 1979), the New Imaginary Audience Scale (Lapsley, Fitzgerald, Rice, & Jackson, 1989), the Personal Fable Scale (Elkind, personal communication, August 10, 1993), the New Personal Fable Scale (Lapsley et al., 1989), and the Separation-Individuation Test of Adolescence (Levine, Green, & Millon, 1986; Levine & Saintonge, 1993). The “New Look” model was generally supported by the data. The various dimensions of separation were significantly associated with the imaginary audience, whereas the dimensions of individuation had stronger links with the personal fable. In addition, some associations were found between the imaginary audience and individuation, as well as between the personal fable and separation. Consistent age and gender differences in the variables studied were found. Results are discussed in the framework of the literature on adolescent egocentrism and on parent-adolescent relations

Hypernetwork functional image representation

Motivated by the human way of memorizing images we introduce their functional representation, where an image is represented by a neural network. For this purpose, we construct a hypernetwork which takes an image and returns weights to the target network, which maps point from the plane (representing positions of the pixel) into its corresponding color in the image. Since the obtained representation is continuous, one can easily inspect the image at various resolutions and perform on it arbitrary continuous operations. Moreover, by inspecting interpolations we show that such representation has some properties characteristic to generative models. To evaluate the proposed mechanism experimentally, we apply it to image super-resolution problem. Despite using a single model for various scaling factors, we obtained results comparable to existing super-resolution methods

Polariton Bose-Einstein condensate at room temperature in a Al(Ga)N nanowire-dielectric microcavity with a spatial potential trap

A spatial potential trap is formed in a 6.0 {\mu}m Al(Ga)N nanowire by varying the Al composition along its length during epitaxial growth. The polariton emission characteristics of a dielectric microcavity with the single nanowire embedded in-plane has been studied at room temperature. Excitation is provided at the Al(Ga)N end of the nanowire and polariton emission is observed from the lowest bandgap GaN region of the nanowire. Comparison of the results with those measured in an identical microcavity with an uniform GaN nanowire and having an identical exciton-photon detuning suggests evaporative cooling of the polaritons as they are transported across the trap in the Al(Ga)N nanowire. Measurement of the spectral characteristics of the polariton emission, their momentum distribution, first-order spatial coherence and time-resolved measurements of polariton cooling provide strong evidence of the formation of an equilibrium Bose-Einstein condensate, a unique state of matter in solid state systems, in the GaN region of the nanowire, at room temperature. An equilibrium condensate is not formed in the GaN nanowire dielectric microcavity without the spatial potential trap.Comment: 28 pages, 6 figures, Submitted to the Proceedings of the National Academy of Sciences of the United States of Americ

Visual Attention for Region of Interest Coding in JPEG 2000

This paper details work undertaken on the application of an algorithm for visual attention (VA) to region of interest (ROI) coding in JPEG 2000 (JP2K). In this way, an "interest ordered" progressive bit-stream is produced where the regions highlighted by the VA algorithm are presented first in bit-stream. The paper briefly outlines the terminology used in JP2K, the packet structure of the bit-stream, and the methods available to achieve ROI coding in JP2K (tiling, coefficient scaling, and code-block selection). The paper then describes how the output of the VA algorithm is post-processed so that an ROI is produced that can be efficiently coded using coefficient scaling in JP2K. Finally, a two alternative forced choice (2AFC) visual trial is undertaken to compare the visual quality of images encoded using the proposed VA ROI algorithm and conventional JP2K. The experimental results show that, while there is no overall preference for the VA ROI encoded images; there is an improvement in perceived image quality at low bit rates (below 0.25 bits per pixel). It is concluded that an overall increase in image quality only occurs when the increase in quality of the ROI more than compensates for the decrease in quality of the image background (i.e., non-ROI)

Dry-reagent disposable dipstick test for visual screening of seven leukemia-related chromosomal translocations

We report the first dry-reagent, disposable, dipstick test for molecular screening of seven chromosomal translocations associated with acute and chronic leukemia. The dipstick assay offers about 10 times higher detectability than agarose gel electrophoresis and, contrary to electrophoresis, allows confirmation of the sequence of the polymerase chain reaction (PCR) product by hybridization within a few minutes without the need of instrumentation. Biotinylated amplified DNA is hybridized with a dA-tailed probe and applied to the strip, which contains oligo(dT)-conjugated gold nanoparticles in dry form. Upon immersion of the strip in the appropriate buffer, the solution migrates and the hybrids are captured by immobilized streptavidin at the test zone generating a characteristic red line. The excess nanoparticles are captured by oligo(dA) strands immobilized at the control zone of the strip producing a second red line. We studied the: t(9;22)(q34;q11), t(15;17)(q22;q21), t(11;17)(q23;q21), t(5;17)(q32;q21), t(11;17)(q13;q21), t(8,21)(q22;q22) and inv(16)(p13;q22) that generate the BCR-ABL, PML-RARa, PLZF-RARa, NPM-RARa, NuMA-RARa, AML1-ETO and CBFβ-MYH11 fusion genes, respectively. A single K562 cell was detectable amidst 10(6) normal leukocytes. A dipstick test was developed for actin, as a reference gene. The dipstick assay with appropriate probes can be used for identification of the fusion transcripts involved in the translocation

A bio-inspired image coder with temporal scalability

We present a novel bio-inspired and dynamic coding scheme for static images. Our coder aims at reproducing the main steps of the visual stimulus processing in the mammalian retina taking into account its time behavior. The main novelty of this work is to show how to exploit the time behavior of the retina cells to ensure, in a simple way, scalability and bit allocation. To do so, our main source of inspiration will be the biologically plausible retina model called Virtual Retina. Following a similar structure, our model has two stages. The first stage is an image transform which is performed by the outer layers in the retina. Here it is modelled by filtering the image with a bank of difference of Gaussians with time-delays. The second stage is a time-dependent analog-to-digital conversion which is performed by the inner layers in the retina. Thanks to its conception, our coder enables scalability and bit allocation across time. Also, our decoded images do not show annoying artefacts such as ringing and block effects. As a whole, this article shows how to capture the main properties of a biological system, here the retina, in order to design a new efficient coder.Comment: 12 pages; Advanced Concepts for Intelligent Vision Systems (ACIVS 2011