Research information management at ISCTE-IUL: the library’s role

ISCTE-IUL is a Portuguese public university with approximately 9000 students enrolled in undergraduate (46%) and postgraduate (54%) programs. The Repository of ISCTE-IUL is running since 2007 sustained by an Open Access Policy approved in the same year. In 2013, the current research information system – Ciência-IUL – became interoperable with the Repository bringing new challenges to SID, and allowing work collaboratively with other services to collect information, improve processes, and reduce duplication of efforts. SID seeks to support researchers throughout the research life cycle aiming to raise awareness of the academic community for Open Science best practices.info:eu-repo/semantics/publishedVersio

Arabidopsis Tetraspanins Are Confined to Discrete Expression Domains and Cell Types in Reproductive Tissues and Form Homo- and Heterodimers When Expressed in Yeast

Tetraspanins are evolutionary conserved transmembrane proteins present in all multicellular organisms. In animals, they are known to act as central organizers of membrane complexes and thought to facilitate diverse biological processes, such as cell proliferation, movement, adhesion, and fusion. The genome of Arabidopsis (Arabidopsis thaliana) encodes 17 members of the tetraspanin family; however, little is known about their functions in plant development. Here, we analyzed their phylogeny, protein topology, and domain structure and surveyed their expression and localization patterns in reproductive tissues. We show that, despite their low sequence identity with metazoan tetraspanins, plant tetraspanins display the typical structural topology and most signature features of tetraspanins in other multicellular organisms. Arabidopsis tetraspanins are expressed in diverse tissue domains or cell types in reproductive tissues, and some accumulate at the highest levels in response to pollination in the transmitting tract and stigma, male and female gametophytes and gametes. Arabidopsis tetraspanins are preferentially targeted to the plasma membrane, and they variously associate with specialized membrane domains, in a polarized fashion, to intercellular contacts or plasmodesmata. A membrane-based yeast (Saccharomyces cerevisiae) two-hybrid system established that tetraspanins can physically interact, forming homo- and heterodimer complexes. These results, together with a likely genetic redundancy, suggest that, similar to their metazoan counterparts, plant tetraspanins might be involved in facilitating intercellular communication, whose functions might be determined by the composition of tetraspanin complexes and their binding partners at the cell surface of specific cell types.Marie Curie International Reintegration grant: (no. IRG–256602), U.S. Department of Agriculture-Agricultural Research Service Current Research Information System grant: (5335–21000–030–00D), Fundação Ciência e Tecnologia Postdoctoral Fellowship: (SFRH/BPD/43584/2008), China Scholarship Council fellowship, UC-Berkeley College of Natural Resources SPUR

As Bibliotecas de Ensino Superior e a gestão de ciência

As Bibliotecas de Ensino Superior (BES) com sistemas CRIS e repositórios institucionais a seu cargo têm vindo a adaptar-se no sentido de responder às necessidades dos seus utilizadores. Passaram a incluir funções de gestão de ciência com benefícios para a comunidade científica e para a instituição. Com a proliferação de plataformas digitais dedicadas à disseminação e comunicação de ciência surgiu a necessidade de apoiar os docentes e investigadores na atualização da sua produção científica e proceder à validação de metadados, ajudando a manter a qualidade e veracidade da informação e contribuir para a simplificação e transparência dos processos de avaliação da instituição. Pretende-se, com este trabalho, descrever a atividade de uma Biblioteca de Ensino Superior com funções de gestão de ciência, enfatizando a interação CRIS-repositório institucional, o processo de validação de metadados e a atualização de perfil de investigador e respetivos currículos dos docentes e investigadores.info:eu-repo/semantics/publishedVersio

As Bibliotecas de Ensino Superior e a Gestão de Ciência

As Bibliotecas de Ensino Superior (BES) com sistemas CRIS e repositórios institucionais a seu cargo têm vindo a adaptar-se no sentido de responder às necessidades dos seus utilizadores. Passaram a incluir funções de gestão de ciência com benefícios para a comunidade científica e para a instituição. Com a proliferação de plataformas digitais dedicadas à disseminação e comunicação de ciência surgiu a necessidade de apoiar os docentes e investigadores na atualização da sua produção científica e proceder à validação de metadados, ajudando a manter a qualidade e veracidade da informação e contribuir para a simplificação e transparência dos processos de avaliação da instituição. Pretende-se, com este trabalho, descrever a atividade de uma Biblioteca de Ensino Superior com funções de gestão de ciência, enfatizando a interação CRIS-repositório institucional, o processo de validação de metadados e a atualização de perfil de investigador e respetivos currículos dos docentes e investigadores.info:eu-repo/semantics/publishedVersio

Diabetes hinders community-acquired pneumonia outcomes in hospitalized patients

This deposit is composed by the main article, and it hasn't any supplementary materials associated.This study aimed to estimate the prevalence of diabetes mellitus (DM) in hospitalized patients with community-acquired pneumonia (CAP) and its impact on hospital length of stay and in-hospital mortality.Pfizer Grant; Ernesto Roma Foundation grant: (FER2014/01)

Sinus Pericranii, a Challenge in Cochlear Implant Surgery

Pretende-se realizar a exposição de um caso clínico, de um doente do sexo masculino, de 19 anos de idade, com o diagnóstico de S. CHARGE. As malformações venosas do osso temporal são raras, mas são um achado comum no Síndrome de CHARGE. Devido a um quadro de surdez neuro-sensorial progressiva à direita e cofose à esquerda (por agenésia do VIII par), tornou-se candidato para colocação de implante coclear aos 16 anos. Por contra-indicação absoluta para colocação do implante à esquerda, foi colocado o implante à direita, por abordagem suprameatal (devido a malformação venosa que impediu uma abordagem convencional). Não foram registadas complicações. Funcionalmente, o implante coclear permitiu a subida dos limiares tonais médios para 42 dB.info:eu-repo/semantics/publishedVersio

Flavoured searches for type-III seesaw at the LHC

We present a reinterpretation of CMS searches for type-III seesaw lepton triplets at the LHC, both for the normal and the inverse seesaw. We find that, in contrast with previous expectations, these searches in the trilepton final state have a good sensitivity to triplets with predominant coupling to the tau lepton. We also show that the limits resulting from direct searches can be neatly presented for arbitrary masses and general flavour mixings. Thus, it turns out that the common (and often unrealistic) simplifying assumptions about the flavour couplings of the triplets used by experimental collaborations to present their results are unnecessary and should be dropped.This work has been supported by Fundação para a Ciência e a Tecnologia (FCT, Portugal) and Ministerio de Ciencia e Innovación (MICINN, Spain) under the bilateral project “Signals of new fermions at colliders” (FCT/1683/27/1/2012/S, AIC-D-2011-0811). F.R.J. and P.M.B. acknowledge support from FCT through the projects CERN/FP/123580/2011, PTDC/FIS/102120/2008 and PEst-OE-FIS-UI0777-2013. J.A.A.S. acknowledges support from MICINN through the projects FPA2006-05294 and FPA2010-17915; from Junta de Andalucía (FQM 101 and FQM 6552) and from FCT (project CERN/ FP/123619/2011)

High risk of cardiovascular episodes and low adherence to risk factors guidelines in a population with diabetes

Although recent guidelines cover therapeutic goals, effective lipid management of patients with type 1 and type 2 diabetes to reduce cardiovascular disease (CVD) risk is still largely unattained. In the present study, we explored the electronic health records (EHR) at a specialized diabetes outpatient clinic to assess, in a real world database, the prevalence of poor lipid management in people with diabetes, the associated characteristics of this population, and the patterns of medication.Amge

Conceptions of basic education teachers about math proof: influence of professional experience

A prova é uma atividade que desempenha um papel fundamental na construção do conhecimento matemático, razão pela qual adquire relevância nos programas escolares de Matemática. Admitindo que as conceções dos professores sobre a prova afetam a forma como ela é tratada em sala de aula, procuramos averiguar as conceções de professores portugueses de Matemática do 3.º ciclo do Ensino Básico (do 7.º ao 9.º ano) sobre diferentes aspetos da prova matemática e a influência que a experiência profissional tem nessas conceções. Adotando uma abordagem metodológica mista, recolhemos os dados através de um questionário, respondido por 72 professores, e de uma entrevista a duas professoras com experiências profissionais diferentes. Os resultados revelam que os professores, sobretudo os que têm menos tempo de docência, consideram que a prova matemática tem uma natureza distinta da de outras disciplinas, é uma atividade essencial para a construção do conhecimento matemático, tem como função verificar e explicar a veracidade de uma afirmação e permite desenvolver o raciocínio e a comunicação matemática. No que respeita à participação dos alunos na atividade de provar, são os professores com mais tempo de docência que mais o destacam, o que permite aos alunos perceberem a natureza desta atividade. Em termos curriculares, são os professores com menos experiência docente que mais concordam com a presença da prova logo nos primeiros anos, embora salientem que esta atividade só faz sentido em alguns tópicos programáticos.Proof is an activity that plays a key role in the construction of mathematical knowledge, which is why it acquires relevance in mathematics programs. Admitting that teachers' conceptions about proof influence how it is handled in the classroom, we tried to investigate the conceptions of Portuguese mathematics teachers from the 3rd cycle of basic education (grade 7 to 9) on different aspects of mathematical proof and the relationship that the teachers’ experience has in these conceptions. Adopting a mixed methodological approach, we collected data through a questionnaire answered by 72 teachers, and an interview with two teachers with different professional experience. The results show that teachers, especially those with less experience, consider that mathematical proof has a distinct nature from other disciplines, it is an essential activity for the construction of mathematical knowledge and its function is to verify and explain the truth of a statement by developing reasoning and mathematical communication. With respect to student participation in the activity of proving, teachers with more teaching experience are the ones that most highlight it, which allows students to realize the nature of this activity. In curriculum terms, teachers with less experience are the ones that most agree with the presence of proof in early grades, while emphasizing that this activity only makes sense in some program topics.Este trabalho contou com o apoio de Fundos Nacionais através da FCT – Fundação para a Ciência e a Tecnologia no âmbito do projeto PEst-OE/CED/UI1661/2014, do CIEdUM e do projeto UID/Multi/04016/2016info:eu-repo/semantics/publishedVersio

Co-firing of biomass and other wastes in fluidised bed systems

A project on co-firing in large-scale power plants burning coal is currently funded by the European Commission. It is called COPOWER. The project involves 10 organisations from 6 countries. The project involves combustion studies over the full spectrum of equipment size, ranging from small laboratory-scale reactors and pilot plants, to investigate fundamentals and operating parameters, to proving trials on a commercial power plant in Duisburg. The power plant uses a circulating fluidized bed boiler. The results to be obtained are to be compared as function of scale-up. There are two different coals, 3 types of biomass and 2 kinds of waste materials are to be used for blending with coal for co-firing tests. The baseline values are obtained during a campaign of one month at the power station and the results are used for comparison with those to be obtained in other units of various sizes. Future tests will be implemented with the objective to achieve improvement on baseline values. The fuels to be used are already characterized. There are ongoing studies to determine reactivities of fuels and chars produced from the fuels. Reactivities are determined not only for individual fuels but also for blends to be used. Presently pilot-scale combustion tests are also undertaken to study the effect of blending coal with different types of biomass and waste materials. The potential for synergy to improve combustion is investigated. Early results will be reported in the Conference. Simultaneously, studies to verify the availability of biomass and waste materials in Portugal, Turkey and Italy have been undertaken. Techno-economic barriers for the future use of biomass and other waste materials are identified. The potential of using these materials in coal fired power stations has been assessed. The conclusions will also be reported