476 research outputs found

    Open Data for Public Administration: Exploitation and semantic organization of institutional web content

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    The project presented has been financed by Government of Aragon and is part of the ''Open Data'' initiative promoted by that organization. Given the amount of unstructured information related to the Government of Aragon currently published on the Internet, with slightly or no standardization and decentralized, it emerges the need to gather it systematically to be offered to all interested collectives from a single access point in a public and structured way. Within this context, ''Aragon Open Data'' project aims to collect, organize, store and maintain updated, Administration''s web information by means of human language and semantic technologies. Firstly, crawling is performed over websites in order to retrieve textual data over which Natural Language Processing (NLP) and ontology-based techniques are applied. Thereafter, results are stored into NoSQL databases, allowing future open access and simple data exploitation. NLP techniques used in the project involve named-entities recognition and classification (NERC) and texts semantic classification and summarization

    Dual regimes of ion migration in high repetition rate femtosecond laser inscribed waveguides

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    Ion migration in high repetition rate femtosecond laser inscribed waveguides is currently being reported in different optical glasses. For the first time we discuss and experimentally demonstrate the presence of two regimes of ion migration found in laser written waveguides. Regime-I, corresponds to the initial waveguide formation mainly via light element migration (in our case atomic weight < 31u), whereas regime-II majorly corresponds to the movement of heavy elements. This behavior brings attention to a problem which has never been analyzed before and that affects laser written active waveguides in which active ions migrate changing their local spectroscopic properties. The migration of active ions may in fact detune the pre-designed optimal values of active photonic devices. This paper experimentally evidences this problem and provides solutions to avert it.Comment: 4 pages, 5 figure

    Evidence-based selection on the appropriate FIT cut-off point in CRC screening programs in the COVID pandemic

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    Background: The COVID pandemic has forced the closure of many colorectal cancer (CRC) screening programs. Resuming these programs is a priority, but fewer colonoscopies may be available. We developed an evidence-based tool for decision-making in CRC screening programs, based on a fecal hemoglobin immunological test (FIT), to optimize the strategy for screening a population for CRC. Methods: We retrospectively analyzed data collected at a regional CRC screening program between February/2014 and November/2018. We investigated two different scenarios: not modifying vs. modifying the FIT cut-off value. We estimated program outcomes in the two scenarios by evaluating the numbers of cancers and adenomas missed or not diagnosed in due time (delayed). Results: The current FIT cut-off (20-mu g hemoglobin/g feces) led to 6, 606 colonoscopies per 100, 000 people invited annually. Without modifying this FIT cut-off value, when the optimal number of individuals invited for colonoscopies was reduced by 10-40%, a high number of CRCs and high-risk adenomas (34-135 and 73-288/100.000-people invited, respectively) will be undetected every year. When the FIT cut-off value was increased to where the colonoscopy demand matched the colonoscopy availability, the number of missed lesions per year was remarkably reduced (9-36 and 29-145/100.000 people, respectively). Moreover, the unmodified FIT scenario outcome was improved by prioritizing the selection process based on sex (males) and age, rather than randomly reducing the number invited. Conclusions: Assuming a mismatch between the availability and demand for annual colonoscopies, increasing the FIT cut-off point was more effective than randomly reducing the number of people invited. Using specific risk factors to prioritize access to colonoscopies should be also considered

    Relationship between the degree of market orientation and the business geographical scope: the case of the spanish company at the end of the 20th century: Relação entre o grau de orientação do mercado e o âmbito geográfico da empresa: o caso da empresa española no final do século XX

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    Este estudo tenta analisar a relação entre o grau de orientação de mercado das empresas espanholas no final do século XX e o seu âmbito geográfico, que se compreende na sua tripla faceta: local, nacional e internacional. Em suma, a orientação de mercado é a filosofia empresarial que orienta as suas ações para a satisfação do cliente, procurando rentabilidade a longo prazo e tendo em conta a concorrência. A literatura existente mostra uma clara ligação entre o nível de orientação de mercado e o desempenho empresarial, daí a sua importância

    Differences between individuals with schizophrenia or obsessive-compulsive disorder and healthy controls in social cognition and mindfulness skills: A controlled study

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    The study of social cognition (SC) has emerged as a key domain of mental health, supporting the notion that poorer performance in SC tasks is linked to psychopathology, although most studies have primarily addressed only schizophrenia (SZ). Some recent studies have also shown deficits of SC in obsessive-compulsive disorder (OCD) patients; however, little is known about how individuals with OCD may differ on SC performance from individuals with SZ. Moreover, initial research in this field suggests that mindfulness skills may be related to SC abilities such as theory of mind (ToM), emotion processing and empathy. Given the potential benefits of mindfulness for treating OCD and SZ, further efforts are needed to understand the association between mindfulness and SC in these populations. The main objective of this study was to compare samples of patients with SZ and OCD to healthy controls (HCs) on several social cognition (SC) domains and mindfulness measures. In total, 30 outpatients diagnosed with SZ, 31 outpatients diagnosed with OCD and 30 healthy controls were assessed in emotion recognition (the Eyes Test), ToM (the Hinting Task), attributional style (the Ambiguous Intentions and Hostility Questionnaire), empathy (the Interpersonal Reactivity Index) and dispositional mindfulness (the MAAS and the FFMQ). Both clinical groups showed poorer performance in emotion recognition and ToM than the HCs. The OCD and SZ patients did not significantly differ in impairment in SC, but the OCD group had higher scores in attributional style (intentionality and anger bias). With regard to mindfulness, the results found lower levels of acting with awareness for the HCs than for either clinical group and higher non-reactivity to inner experience for the HCs than for the individuals with OCD; the results also yielded significant correlations between SC and mindfulness. In conclusion, these findings revealed that SC abilities were impaired in the SZ and OCD groups compared to the HC group, suggesting a similar disrupted pattern in both clinical groups. Aspects of dispositional mindfulness were differentially associated with SC, which may suggest their potential role in novel transdiagnostic interventions

    The gambling habits of university students in Aragon, Spain: a cross-sectional study

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    Gambling has become a routine form of entertainment for many young people. The aim of this study was to describe the gambling behavior that university students are developing in Aragon, Spain, and to analyze whether these habits are more common among students of sports science, on the assumption that they are more likely to have a higher exposure to betting company marketing. A cross-sectional design was applied, with data collected on advertising exposure, gambling habits and experiences, and opinions on the impact of gambling and its regulation from 516 undergraduate students from the University of Zaragoza. The online survey included ad hoc questions and the “Pathological Gambling Short Questionnaire” to screen for potential gambling disorders. Almost half of the sample had bet money at least once in their life (48.1%), and 2.4% screened positive for consideration of a possible diagnosis of pathological gambling. Betting shops (44.2%) were the most common gambling option, and students of sports science showed a higher prevalence of pathological gambling and had greater tendencies to make bets. Gambling is perceived as a normal leisure activity by a significant part of university students. The development of transversal strategies is required to raise awareness towards the potential dangers of gambling. © 2022 by the authors. Licensee MDPI, Basel, Switzerland

    Genetic structure among Charadrius plovers on the African mainland and islands of Madagascar and St Helena

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    Colonisation of islands by long distance dispersers has great impact on genetic diversification among populations and may spearhead speciation events. We investigated intra‐ and interspecific divergence in Charadrius plovers with populations on mainland Africa, Madagascar and St Helena. We analysed microsatellite loci and sequence data from four nuclear and two mitochondrial gene regions. Charadrius plovers are shorebirds with high dispersal and mobility. Our results confirmed genetic differentiation between Madagascar and mainland populations of three plover species (White‐fronted Plovers, C. marginatus; Kittlitz's Plovers, C. pecuarius; and based on sequence data only, Three‐banded Plovers, C. tricollaris) but highlight substantial variation in levels of intraspecific divergence among the three species. Namely, the Kittlitz's Plover, a dispersive habitat generalist with a polygamous mating system, exhibited lower island‐mainland differentiation (0.05% COI sequence divergence) than two monogamous species, the White‐fronted Plover (0.6% COI divergence) and Three‐banded Plover (1.6% COI divergence). In addition, past colonisation of the islands of St Helena and Madagascar by ancestors of today's Kittlitz's Plover led to the evolution of two endemic island species, the Madagascar Plover C. thoracicus and the more closely‐related St Helena Plover C. sanctaehelenae. We discuss the factors driving species differences in island‐mainland divergence, and highlight the importance of conserving genetically unique island populations and island habitats to safe‐guard future evolutionary potential

    Efficacy of memantine in the treatment of fibromyalgia: A double-blind, randomised, controlled trial with 6-month follow-up.

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    Fibromyalgia (FM) is a prevalent and disabling chronic disease. Recent studies have found elevated levels of glutamate in several brain regions, leading to hypotheses about the usefulness of glutamate-blocking drugs such as memantine in the treatment of FM. The aim of this study was to evaluate the efficacy of memantine in the treatment of pain and other clinical variables (global function, clinical impression, depression, anxiety, quality of life) in FM patients. A double-blind, parallel randomised controlled trial was developed. A total of 63 patients diagnosed with FM were recruited from primary health care centres in Zaragoza, Spain. Memantine was administered at doses of 20mg/d after 1 month of titration. Assessments were carried out at baseline, posttreatment, and 3- and 6-month follow-up. Compared with a placebo group, memantine significantly decreased ratings on a pain visual analogue scale (Cohen's d=1.43 at 6 months) and pain measured with a sphygmomanometer (d=1.05). All other secondary outcomes except anxiety also improved, with moderate-to-large effect sizes at 6 months. Compared with placebo, the absolute risk reduction obtained with memantine was 16.13% (95% confidence interval=2.0% to 32.6%), and the number needed to treat was 6.2 (95% confidence interval=3 to 47). Tolerance was good, with dizziness (8 patients) and headache (4 patients) being the most frequent side effects of memantine. Although additional studies with larger sample sizes and longer follow-up times are needed, this study provides preliminary evidence of the utility of memantine for the treatment of FM
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