1,705 research outputs found
Self-Affirmation Improves Problem-Solving under Stress
High levels of acute and chronic stress are known to impair problem-solving and creativity on a broad range of tasks. Despite this evidence, we know little about protective factors for mitigating the deleterious effects of stress on problem-solving. Building on previous research showing that self-affirmation can buffer stress, we tested whether an experimental manipulation of self-affirmation improves problem-solving performance in chronically stressed participants. Eighty undergraduates indicated their perceived chronic stress over the previous month and were randomly assigned to either a self-affirmation or control condition. They then completed 30 difficult remote associate problem-solving items under time pressure in front of an evaluator. Results showed that self-affirmation improved problem-solving performance in underperforming chronically stressed individuals. This research suggests a novel means for boosting problem-solving under stress and may have important implications for understanding how self-affirmation boosts academic achievement in school settings. © 2013 Creswell et al
The interaction of lean and building information modeling in construction
Lean construction and Building Information Modeling are quite different initiatives, but both are having profound impacts on the construction industry. A rigorous analysis of the myriad specific interactions between them indicates that a synergy exists which, if properly understood in theoretical terms, can be exploited to improve construction processes beyond the degree to which it might be improved by application of either of these paradigms independently. Using a matrix that juxtaposes BIM functionalities with prescriptive lean construction principles, fifty-six interactions have been identified, all but four of which represent constructive interaction. Although evidence for the majority of these has been found, the matrix is not considered complete, but rather a framework for research to
explore the degree of validity of the interactions. Construction executives, managers, designers and developers of IT systems for construction can also benefit from the framework as an aid to recognizing the potential synergies when planning their lean and BIM adoption strategies
How and When Socially Entrepreneurial Nonprofit Organizations Benefit From Adopting Social Alliance Management Routines to Manage Social Alliances?
Social alliance is defined as the collaboration between for-profit and nonprofit organizations. Building on the insights derived from the resource-based theory, we develop a conceptual framework to explain how socially entrepreneurial nonprofit organizations (SENPOs) can improve their social alliance performance by adopting strategic alliance management routines. We test our framework using the data collected from 203 UK-based SENPOs in the context of cause-related marketing campaign-derived social alliances. Our results confirm a positive relationship between social alliance management routines and social alliance performance. We also find that relational mechanisms, such as mutual trust, relational embeddedness, and relational commitment, mediate the relationship between social alliance management routines and social alliance performance. Moreover, our findings suggest that different types of social alliance motivation can influence the impact of social alliance management routines on different types of the relational mechanisms. In general, we demonstrate that SENPOs can benefit from adopting social alliance management routines and, in addition, highlight how and when the social alliance management routines–social alliance performance relationship might be shaped. Our study offers important academic and managerial implications, and points out future research directions
Evidence for long-term sensitization of the bowel in patients with post-infectious-IBS.
Post-infectious irritable bowel syndrome (PI-IBS) is a common gastrointestinal disorder characterized by persistent abdominal pain despite recovery from acute gastroenteritis. The underlying mechanisms are unclear, although long-term changes in neuronal function, and low grade inflammation of the bowel have been hypothesized. We investigated the presence and mechanism of neuronal sensitization in a unique cohort of individuals who developed PI-IBS following exposure to contaminated drinking water 7 years ago. We provide direct evidence of ongoing sensitization of neuronal signaling in the bowel of patients with PI-IBS. These changes occur in the absence of any detectable tissue inflammation, and instead appear to be driven by pro-nociceptive changes in the gut micro-environment. This is evidenced by the activation of murine colonic afferents, and sensitization responses to capsaicin in dorsal root ganglia (DRGs) following application of supernatants generated from tissue biopsy of patients with PI-IBS. We demonstrate that neuronal signaling within the bowel of PI-IBS patients is sensitized 2 years after the initial infection has resolved. This sensitization appears to be mediated by a persistent pro-nociceptive change in the gut micro-environment, that has the capacity to stimulate visceral afferents and facilitate neuronal TRPV1 signaling
Foreword: The International Law Legacy of the Obama Administration
An introduction is presented in which editor discusses various articles within the issue based on the legacy of U.S. President Barack Obama\u27s administration on right to use force in self-defense against non-state actors, foreign policy accomplishments in the Middle East and climate change
Foreword: The International Law Legacy of the Obama Administration
An introduction is presented in which editor discusses various articles within the issue based on the legacy of U.S. President Barack Obama\u27s administration on right to use force in self-defense against non-state actors, foreign policy accomplishments in the Middle East and climate change
Causal hierarchy within the thalamo-cortical network in spike and wave discharges
Background: Generalised spike wave (GSW) discharges are the electroencephalographic (EEG) hallmark of absence seizures, clinically characterised by a transitory interruption of ongoing activities and impaired consciousness, occurring during states of reduced awareness. Several theories have been proposed to explain the pathophysiology of GSW discharges and the role of thalamus and cortex as generators. In this work we extend the existing theories by hypothesizing a role for the precuneus, a brain region neglected in previous works on GSW generation but already known to be linked to consciousness and awareness. We analysed fMRI data using dynamic causal modelling (DCM) to investigate the effective connectivity between precuneus, thalamus and prefrontal cortex in patients with GSW discharges. Methodology and Principal Findings: We analysed fMRI data from seven patients affected by Idiopathic Generalized Epilepsy (IGE) with frequent GSW discharges and significant GSW-correlated haemodynamic signal changes in the thalamus, the prefrontal cortex and the precuneus. Using DCM we assessed their effective connectivity, i.e. which region drives another region. Three dynamic causal models were constructed: GSW was modelled as autonomous input to the thalamus (model A), ventromedial prefrontal cortex (model B), and precuneus (model C). Bayesian model comparison revealed Model C (GSW as autonomous input to precuneus), to be the best in 5 patients while model A prevailed in two cases. At the group level model C dominated and at the population-level the p value of model C was ∼1. Conclusion: Our results provide strong evidence that activity in the precuneus gates GSW discharges in the thalamo-(fronto) cortical network. This study is the first demonstration of a causal link between haemodynamic changes in the precuneus - an index of awareness - and the occurrence of pathological discharges in epilepsy. © 2009 Vaudano et al
Modeling the isotopic evolution of snowpack and snowmelt : Testing a spatially distributed parsimonious approach
This work was funded by the NERC/JPI SIWA project (NE/M019896/1) and the European Research Council ERC (project GA 335910 VeWa). The Krycklan part of this study was supported by grants from the Knut and Alice Wallenberg Foundation (Branch-points), Swedish Research Council (SITES), SKB and Kempe foundation. The data and model code is available upon request. Authors declare that they have no conflict of interest. We would like to thank the three anonymous reviewers for their constructive comments that improved the manuscript.Peer reviewedPublisher PD
Meltwater produced by wind–albedo interaction stored in an East Antarctic ice shelf
Surface melt and subsequent firn air depletion can ultimately
lead to disintegration of Antarctic ice shelves1,2 causing
grounded glaciers to accelerate3 and sea level to rise. In
the Antarctic Peninsula, foehn winds enhance melting near
the grounding line4, which in the recent past has led to the
disintegration of the most northerly ice shelves5,6. Here, we
provide observational and model evidence that this process
also occurs over an East Antarctic ice shelf, where meltwaterinduced
firn air depletion is found in the grounding zone.
Unlike the Antarctic Peninsula, where foehn events originate
from episodic interaction of the circumpolar westerlies with
the topography, in coastal East Antarctica high temperatures
are caused by persistent katabatic winds originating from the
ice sheet’s interior. Katabatic winds warm and mix the air
as it flows downward and cause widespread snow erosion,
explaining >3 K higher near-surface temperatures in summer
and surface melt doubling in the grounding zone compared with
its surroundings. Additionally, these winds expose blue ice and
firn with lower surface albedo, further enhancing melt. The
in situ observation of supraglacial flow and englacial storage
of meltwater suggests that ice-shelf grounding zones in East
Antarctica, like their Antarctic Peninsula counterparts, are
vulnerable to hydrofracturing7
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