168 research outputs found

    Les biotechnologies végétales appropriées dans le contexte du dialogue Nord-Sud

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    Appropriate plant biotechnology in the context of the dialogue between North and South. Appropriateness of any technology must take into consideration the ethical problems and the social, economical, scientific and ecological environment. For developing countries, plant biotechnologies definitely open interesting perspectives, but also raise potential problems, because their integration and valorisation require a progressive and adapted development. Biotechnologies depend on legal and physical infrastructures, as well as human skills for on-site control corresponding to the needs of the relevant populations and to the global environment

    Des modèles biologiques à l'amélioration des plantes

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    Littérature scientifique et formation à l'information, la situation des bioingénieurs à Gembloux Agro-Bio Tech (ULg) (synthèse bibliographique)

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    Scholarly publication and education in Information Literacy within the bioengineering curriculum, the Gembloux Agro-Bio Tech (ULg) case. A review. This article is based on a doctoral study on the role of scientific literature in the teaching of bioengineering at Gembloux. It is essentially a summary incorporating recent advances in Information Literacy. Data analysis indicates that the bioengineers working at Gembloux publish at least as much as research as other scientists in Belgium. These bioengineers choose to publish articles in journals with a high impact factor, preferring to read articles rather than books and using all the electronic resources available to them. Their fields of research, and reading, go beyond the bounds of agronomy in the strictest sense. The bioengineering courses provided at Gembloux are based on the concept of Information Literacy. This concept refers to a set of skills that allow individuals to recognize an information need and enable them to locate, evaluate and use the required information. The area of Information Literacy has evolved over the last two decades. The scope of education of this area goes well beyond the bounds of the library. In addition to intellectual skills, Information Literacy also involves social and cultural skills. These include an understanding of media and new information technologies, without being reduced to technical or technological skills. At Gembloux, education in Information Literacy is included in the student's timetable. It incorporates the production of scientific papers and is based on a methodological approach with its own didactic and specific content

    Des modèles biologiques à l'amélioration des plantes

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    Identification of host genes potentially implicated in the Malus pumila and ‘Candidatus Phytoplasma mali’ interactions

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    Two‘Candidatus Phytoplasma mali’ strains (AP and AT), were studied in experimentally infected apple trees to analyze transcriptional profiles during interaction with phytoplasmas. Three groups of sample combinations were employed: healthy - infected, symptomatic - non-symptomatic, and AP-infected - AT-infected sample. The majority of genes were differently expressed between healthy and infected samples. Changes in gene expression involved a wide spectrum of biological functions, including processes of metabolism, cell defence, photosynthesis, transport, transcription, signal transduction and protein synthesis. The possible effect of phytoplasma infection on these processes and their relationships with disease development, symptom appearance and possible plant defence system is discussed. Keywords: Apple, phytoplasmas, ‘Ca. P. mali’, gene expression, transcriptom

    Potentialités androgénétiques du palmier dattier Phoenix dactylifera L. et culture in vitro d'anthères

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    Genetic potentialities if five male date palm genotypes, and in vitro culture of anthers. The experimental results derived from the study of five date palm (Phoenix dactylifera L.) genotypes indicate that the ability of microspores to divide varies with genotype and culture medium. The highest frequency of microspore division is obtained with the induction medium [Murashige and Skoog (MS 1962) mineral elements, 2,4-dichlorophenoxyacetique (2,4-D), 2-isopentenylaminopurine (2-IP)] containing activated charcoal. The pollinator T106 was considered as the most efficient genotype in our experimentatio

    Mycosphaerella leaf spot diseases of bananas: present status and outlook: Proceedings of the 2nd international workshop on Mycosphaerella leaf spot diseases held in San José, Costa Rica, 20-23 may 2002

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    Thriteen years after the 1st international workshop on Sigatoka diseases of Banana held in San José, Costa Rica, in March 1989, the present proceedings offer an overview of the current situation regarding Mycosphaerella leaf spot diseases at the global level

    Temporal changes in the epidemiology, management, and outcome from acute respiratory distress syndrome in European intensive care units: a comparison of two large cohorts

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    Background: Mortality rates for patients with ARDS remain high. We assessed temporal changes in the epidemiology and management of ARDS patients requiring invasive mechanical ventilation in European ICUs. We also investigated the association between ventilatory settings and outcome in these patients. Methods: This was a post hoc analysis of two cohorts of adult ICU patients admitted between May 1–15, 2002 (SOAP study, n = 3147), and May 8–18, 2012 (ICON audit, n = 4601 admitted to ICUs in the same 24 countries as the SOAP study). ARDS was defined retrospectively using the Berlin definitions. Values of tidal volume, PEEP, plateau pressure, and FiO2 corresponding to the most abnormal value of arterial PO2 were recorded prospectively every 24 h. In both studies, patients were followed for outcome until death, hospital discharge or for 60 days. Results: The frequency of ARDS requiring mechanical ventilation during the ICU stay was similar in SOAP and ICON (327[10.4%] vs. 494[10.7%], p = 0.793). The diagnosis of ARDS was established at a median of 3 (IQ: 1–7) days after admission in SOAP and 2 (1–6) days in ICON. Within 24 h of diagnosis, ARDS was mild in 244 (29.7%), moderate in 388 (47.3%), and severe in 189 (23.0%) patients. In patients with ARDS, tidal volumes were lower in the later (ICON) than in the earlier (SOAP) cohort. Plateau and driving pressures were also lower in ICON than in SOAP. ICU (134[41.1%] vs 179[36.9%]) and hospital (151[46.2%] vs 212[44.4%]) mortality rates in patients with ARDS were similar in SOAP and ICON. High plateau pressure (> 29 cmH2O) and driving pressure (> 14 cmH2O) on the first day of mechanical ventilation but not tidal volume (> 8 ml/kg predicted body weight [PBW]) were independently associated with a higher risk of in-hospital death. Conclusion: The frequency of and outcome from ARDS remained relatively stable between 2002 and 2012. Plateau pressure > 29 cmH2O and driving pressure > 14 cmH2O on the first day of mechanical ventilation but not tidal volume > 8 ml/kg PBW were independently associated with a higher risk of death. These data highlight the continued burden of ARDS and provide hypothesis-generating data for the design of future studies

    The clinical relevance of oliguria in the critically ill patient : Analysis of a large observational database

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    Funding Information: Marc Leone reports receiving consulting fees from Amomed and Aguettant; lecture fees from MSD, Pfizer, Octapharma, 3 M, Aspen, Orion; travel support from LFB; and grant support from PHRC IR and his institution. JLV is the Editor-in-Chief of Critical Care. The other authors declare that they have no relevant financial interests. Publisher Copyright: © 2020 The Author(s). Copyright: Copyright 2020 Elsevier B.V., All rights reserved.Background: Urine output is widely used as one of the criteria for the diagnosis and staging of acute renal failure, but few studies have specifically assessed the role of oliguria as a marker of acute renal failure or outcomes in general intensive care unit (ICU) patients. Using a large multinational database, we therefore evaluated the occurrence of oliguria (defined as a urine output 16 years) patients in the ICON audit who had a urine output measurement on the day of admission were included. To investigate the association between oliguria and mortality, we used a multilevel analysis. Results: Of the 8292 patients included, 2050 (24.7%) were oliguric during the first 24 h of admission. Patients with oliguria on admission who had at least one additional 24-h urine output recorded during their ICU stay (n = 1349) were divided into three groups: transient - oliguria resolved within 48 h after the admission day (n = 390 [28.9%]), prolonged - oliguria resolved > 48 h after the admission day (n = 141 [10.5%]), and permanent - oliguria persisting for the whole ICU stay or again present at the end of the ICU stay (n = 818 [60.6%]). ICU and hospital mortality rates were higher in patients with oliguria than in those without, except for patients with transient oliguria who had significantly lower mortality rates than non-oliguric patients. In multilevel analysis, the need for RRT was associated with a significantly higher risk of death (OR = 1.51 [95% CI 1.19-1.91], p = 0.001), but the presence of oliguria on admission was not (OR = 1.14 [95% CI 0.97-1.34], p = 0.103). Conclusions: Oliguria is common in ICU patients and may have a relatively benign nature if only transient. The duration of oliguria and need for RRT are associated with worse outcome.publishersversionPeer reviewe
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