Risk Trajectories of Self-Destructiveness in Adolescence: Family Core Influences

The study of family factors, (namely, parenting, attachment and family functioning) that can either reduce or increase risk factors during adolescent development is crucial to the early identification of adolescents at risk for self-destructive thoughts and behaviors (SDTB). Altough several studies have highlighted the role of family factors, few have analysed the joint impact of parenting styles and attachment in SDT. This study aimed to: (1) to identify the dimensions of parenting styles and parental attachment that predict SDTB; (2) to determine the mediation effect of cohesion on the relation between these predictors and reports of SDTB; and (3) to analyze sex and age differences in the abovementioned process. Participants included 1,266 Portuguese adolescents with a mean age of 15.9 years. Structural equation modeling demonstrated that paternal and maternal rejection and paternal control were the most accurate predictors of SDTB, emphasizing their role as risk factors for maladaptive trajectories with reports of SDTB. Results clearly emphasized the relevancy of the fathers’ role in such maladaptive trajectories. Additionally, a mediation effect of cohesion and a moderation of sex were also found. This study highlights the importance of intervening with the family in preventive and therapeutic contexts regarding adolescents’ well-being and their relationship with parents

Cortical contributions to impaired contour integration in schizophrenia

OBJECTIVES: Visual perceptual organization impairments in schizophrenia (SCZ) are well established, but their neurobiological bases are not. The current study used the previously validated Jittered Orientation Visual Integration (JOVI) task, along with fMRI, to examine the neural basis of contour integration (CI), and its impairment in SCZ. CI is an aspect of perceptual organization in which multiple distinct oriented elements are grouped into a single continuous boundary or shape. METHODS: On the JOVI, five levels of orientational jitter were added to non-contiguous closed contour elements embedded in background noise to progressively increase the difficulty in perceiving contour elements as left- or right-pointing ovals. Multi-site fMRI data were analyzed for 56 healthy control subjects and 47 people with SCZ. RESULTS: SCZ patients demonstrated poorer CI, and this was associated with increased activation in regions involved in global shape processing and visual attention, namely the lateral occipital complex and superior parietal lobules. There were no brain regions where controls demonstrated more activation than patients. CONCLUSIONS: CI impairment in this sample of outpatients with SCZ was related to excessive activation in regions associated with object processing and allocation of visual-spatial attention. There was no evidence for basic impairments in contour element linking in the fMRI data. The latter may be limited to poor outcome patients, where more extensive structural and functional changes in the occipital lobe have been observed