311 research outputs found
Influence of intrafamilial abuse in children's change of values towards their parents
The socialization that parents and society exercise on children instills in them a set of values towards parents. Some of these values are not lying, feeling affection for the parents, and wanting to have contact with them. In this work, we attempt to determine whether these values change in the face of intrafamilial abuse. To that end, an incidental sample was used, consisting of 2730 minors aged between 6 to 18 years, who had never suffered abuse. They were asked to put themselves in the place of the main character of a story. The story varied depending on the conditions to be studied: observation and direct suffering or account of the abuse by another, type of abuse (physical or psychological), who perpetrated the abuse (custodian or non-custodial), and who received it (the other custodian or the minor). The results show that, as a rule, children lie to conceal both parents' abusive behavior; they love their parents and want to have contact with them, even in the presence of abuse. Notwithstanding that in the presence of abuse by one of their parents, children still love them and want to have contact with both parents, a significant number of children, however, stop loving them or want to have contact with the abusive parent. These results undermine what is defended by theories like PAS with no scientific evidence, and underline the need to use scientific procedures to test the reliability of minors’ testimony based on the idea that children tell the truth.Die von Eltern und Gesellschaft initiierten Sozialisationsprozesse erziehen Kindern eine Reihe von Werten im Umgang mit ihren Eltern an. Einige dieser Werte sind beispielsweise: nicht zu lügen, eine Zuneigung zu den Eltern zu verspüren und Kontakt zu ihnen haben zu wollen. In dieser wissenschaftlichen Arbeit wird versucht zu untersuchen, ob sich diese Werte bei innerfamilialem Missbrauch verändern. Zu diesem Zweck wurde eine Stichprobe von 2730 Minderjährigen im Alter zwischen 6 und 18 Jahren, die noch nie missbraucht wurden, herangezogen. Sie wurden gebeten, sich in die Hauptfigur einer Geschichte hineinzuversetzen. Die Geschichte variierte je nach den zu untersuchenden Bedingungen: Beobachtung und direktes Erleiden oder Erzählung des Missbrauchs durch andere, Art des Missbrauchs (physisch oder psychisch), wer den Missbrauch begangen hat (erziehungsberechtigter oder nicht erziehungsberechtigter Elternteil) und wer dem Missbrauch ausgesetzt war (der andere Elternteil oder das Kind). Die Ergebnisse zeigen, dass Kinder in der Regel lügen, wenn es darum geht das missbräuchliche Verhalten von einem der beiden Elternteile zu verbergen. Sie lieben ihre Eltern und möchten Kontakt zu ihnen haben, selbst im Falle von Missbrauch. Ungeachtet dessen, das einige Kinder bei Misshandlung durch einen ihrer Elternteile, beide Eltern immer noch lieben und Kontakt zu ihnen haben wollen, hört eine signifikante Anzahl von Kinder auf, den missbrauchenden Elternteil zu lieben oder Kontakt zu ihm haben zu wollen. Diese Ergebnisse falsifizieren, was von Theorien wie PAS ohne wissenschaftliche Beweise behauptet wird und unterstreichen die Notwendigkeit der Verwendung wissenschaftlicher Verfahren, die auf der Idee fußen, dass Kinder die Wahrheit sagen, zur zuverlässigen Untersuchung der Zeugenaussagen von Kindern
Effect of variation in oxytetracycline treatment of Lawsonia intracellularis diahrea in nursery pigs on treatment-efficacy and resistance development
A Danish research project, MINIRESIST, investigated the consequences of varying doses and treatment strategies for oxytetracycline treatment of Lawsonia intracellularis diarrhea in nursery pigs. Batches of nursery pigs in five herds were randomly allocated to one of five treatment protocols (batch treatment orally with high, normal and low doses; penwise treatment with normal dose and injection treatment with normal dose). Outcomes, in terms of reduction of L. intracellularis determined by qPCR, growth rate and fecal dry matter content (determined on 30 pigs per batch in 61 batches), and levels of tetracyclineresistant coliforms, and quantification of resistance genes in intestinal content (determined on 15 pigs per batch in 80 batches), were determined and analyzed statistically
Early mortality from colorectal cancer in England: a retrospective observational study of the factors associated with death in the first year after diagnosis
Background: The United Kingdom performs poorly in international comparisons of colorectal cancer survival with much of the deficit owing to high numbers of deaths close to the time of diagnosis. This retrospective cohort study investigates the patient, tumour and treatment characteristics of those who die in the first year after diagnosis of their disease. Methods: Patients diagnosed with colon (n=65,733) or rectal (n=26,123) cancer in England between 2006 and 2008 were identified in the National Cancer Data Repository. Multivariable logistic regression was used to investigate the odds of death within 1 month, 1-3 months and 3-12 months after diagnosis. Results: In all, 11.5% of colon and 5.4% of rectal cancer patients died within a month of diagnosis: this proportion decreased significantly over the study period. For both cancer sites, older age, stage at diagnosis, deprivation and emergency presentation were associated with early death. Individuals who died shortly after diagnosis were also more likely to have missing data about important prognostic factors such as disease stage and treatment. Conclusion: Using routinely collected data, at no inconvenience to patients, we have identified some important areas relating to early deaths from colorectal cancer, which merit further research
Leukocytes Are Recruited through the Bronchial Circulation to the Lung in a Spontaneously Hypertensive Rat Model of COPD
Chronic obstructive pulmonary disease (COPD) kills approximately 2.8 million people each year, and more than 80% of COPD cases can be attributed to smoking. Leukocytes recruited to the lung contribute to COPD pathology by releasing reactive oxygen metabolites and proteolytic enzymes. In this work, we investigated where leukocytes enter the lung in the early stages of COPD in order to better understand their effect as a contributor to the development of COPD. We simultaneously evaluated the parenchyma and airways for neutrophil accumulation, as well as increases in the adhesion molecules and chemokines that cause leukocyte recruitment in the early stages of tobacco smoke induced lung disease. We found neutrophil accumulation and increased expression of adhesion molecules and chemokines in the bronchial blood vessels that correlated with the accumulation of leukocytes recovered from the lung. The expression of adhesion molecules and chemokines in other vascular beds did not correlate with leukocytes recovered in bronchoalveolar lavage fluid (BALF). These data strongly suggest leukocytes are recruited in large measure through the bronchial circulation in response to tobacco smoke. Our findings have important implications for understanding the etiology of COPD and suggest that pharmaceuticals designed to reduce leukocyte recruitment through the bronchial circulation may be a potential therapy to treat COPD
Intradermal Anti-Loxosceles Fab Fragments Attenuate Dermonecrotic Arachnidism
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/73371/1/j.1553-2712.1999.tb00133.x.pd
The STRANDS project: long-term autonomy in everyday environments
Thanks to the efforts of the robotics and autonomous systems community, the myriad applications and capacities of robots are ever increasing. There is increasing demand from end users for autonomous service robots that can operate in real environments for extended periods. In the Spatiotemporal Representations and Activities for Cognitive Control in Long-Term Scenarios (STRANDS) project (http://strandsproject.eu), we are tackling this demand head-on by integrating state-of-the-art artificial intelligence and robotics research into mobile service robots and deploying these systems for long-term installations in security and care environments. Our robots have been operational for a combined duration of 104 days over four deployments, autonomously performing end-user-defined tasks and traversing 116 km in the process. In this article, we describe the approach we used to enable long-term autonomous operation in everyday environments and how our robots are able to use their long run times to improve their own performance
Effect of variation in oxytetracycline treatment of Lawsonia intracellularis diahrea in nursery pigs on treatment-efficacy and resistance development
Prospective phase II study of preoperative short-course radiotherapy for rectal cancer with twice daily fractions of 2.9 Gy to a total dose of 29 Gy - Long-term results
Elite Refereeing in Professional Soccer: A Case Study of Mental Skills Support
Refereeing a high-profile soccer game requires a unique blend of sports-specific knowledge, physical abilities, and mental skills. While mental skills instruction has been seen as an integral element of performance enhancement in elite sport, the application of sport psychology intervention for referees and match officials is far less prominent. This case study briefly describes the levels of stress associated with refereeing elite soccer matches and the impact of stress on officiating performance and subsequent self-confidence of soccer referees. The work then outlines the program of mental skills intervention that was delivered to an elite soccer referee working within the Scottish professional soccer leagues. The program of mental skills embraced five stages: (1) Education; (2) Assessment/ profiling; (3) Mental skill learning; (4) Application of mental skills in context; and (5) Evaluation, and this article centers on the way in which each of these stages was carried out. The case study describes how the mental skills instruction program was associated with improved refereeing performance, and provides some tentative advice for sport psychology practitioners who may wish to provide consultancy services within the domain of sports officiating
Modulation of epithelial sodium channel (ENaC) expression in mouse lung infected with Pseudomonas aeruginosa
BACKGROUND: The intratracheal instillation of Pseudomonas aeruginosa entrapped in agar beads in the mouse lung leads to chronic lung infection in susceptible mouse strains. As the infection generates a strong inflammatory response with some lung edema, we tested if it could modulate the expression of genes involved in lung liquid clearance, such as the α, β and γ subunits of the epithelial sodium channel (ENaC) and the catalytic subunit of Na(+)-K(+)-ATPase. METHODS: Pseudomonas aeruginosa entrapped in agar beads were instilled in the lung of resistant (BalB/c) and susceptible (DBA/2, C57BL/6 and A/J) mouse strains. The mRNA expression of ENaC and Na(+)-K(+)-ATPase subunits was tested in the lung by Northern blot following a 3 hours to 14 days infection. RESULTS: The infection of the different mouse strains evoked regulation of α and β ENaC mRNA. Following Pseudomonas instillation, the expression of αENaC mRNA decreased to a median of 43% on days 3 and 7 after infection and was still decreased to a median of 45% 14 days after infection (p < 0.05). The relative expression of βENaC mRNA was transiently increased to a median of 241%, 24 h post-infection before decreasing to a median of 43% and 54% of control on days 3 and 7 post-infection (p < 0.05). No significant modulation of γENaC mRNA was detected although the general pattern of expression of the subunit was similar to α and β subunits. No modulation of α(1)Na(+)-K(+)-ATPase mRNA, the catalytic subunit of the sodium pump, was recorded. The distinctive expression profiles of the three subunits were not different, between the susceptible and resistant mouse strains. CONCLUSIONS: These results show that Pseudomonas infection, by modulating ENaC subunit expression, could influence edema formation and clearance in infected lungs
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