349 research outputs found

    Interactions of hadrons in the CALICE SiW ECAL prototype

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    This article presents results of test beams obtained for pions with energies between 2 and 10 GeV which interact in the volume of the highly granular CALICE Silicon-Tungsten electromagnetic calorimeter prototype (SiW ECAL). An algorithm optimised to find interactions in the SiW ECAL at small hadron energies is developed. This allows identifying the interaction point in the calorimeter at an efficiency between 62% and 83% depending on the energy of the primary particle. The unprecedented granularity of the SiW ECAL allows for the distinction between different interaction types. This in turn permits more detailed examinations of hadronic models than was possible with traditional calorimeters. So far, it is possible to disentangle minimum ionising particle (MIP) events, elastic π-nucleus scattering and spallation reactions which lead to the start of a internuclear cascade or which result in a small number of highly ionising particles. Various observables are compared with predictions from hadronic physics lists as contained in the simulation toolkit geant4

    A precise characterisation of the top quark electro-weak vertices at the ILC

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    Top quark production in the process e+ettˉe^+e^- \to t\bar{t} at a future linear electron positron collider with polarised beams is a powerful tool to determine indirectly the scale of new physics. The presented study, based on a detailed simulation of the ILD detector concept, assumes a centre-of-mass energy of s=500\sqrt{s}=500\,GeV and a luminosity of L=500fb1\mathcal{L}=500\,{\rm fb}^{-1} equally shared between the incoming beam polarisations of Pe,Pe+=±0.8,0.3\mathcal{P}_{e^-}, \mathcal{P}_{e^+} =\pm0.8,\mp0.3. Events are selected in which the top pair decays semi-leptonically and the cross sections and the forward-backward asymmetries are determined. Based on these results, the vector, axial vector and tensorial CPCP conserving couplings are extracted separately for the photon and the Z0Z^0 component. With the expected precision, a large number of models in which the top quark acts as a messenger to new physics can be distinguished with many standard deviations. This will dramatically improve expectations from e.g. the LHC for electro-weak couplings of the top quark.Comment: This work is an update of arXiv:1307.8102, minor changes w.r.t. v1 (typos, wrong grammar, incomplete sentences etc.

    Leading interactions in the β\beta-SrV6O15Sr V_6 O_{15} compound

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    The present study shows that the electronic structure of the β\beta-AV_6O_15AV\_6O\_{15} family of compounds (A=Sr,Ca,Na...A = Sr, Ca, Na ...) is based on weakly interacting two-leg ladders, in contrast with the zig-zag chain model one could expect from their crystal structure. Spin dimer analysis, based on extended H\"{u}ckel tight-binding calculations, was performed to determine the structure of the dominant transfer and magnetic interactions in the room temperature β\beta-SrV_6O_15SrV\_6O\_{15} phase. Two different two-legs ladders, associated with different charge/spin orders are proposed to describe these one-dimensional β\beta-type systems. The antiferromagnetic ladders are packed in an 'IPN' geometry and coupled to each other through weak antiferromagnetic interactions. This arrangement of the dominant interactions explains the otherwise surprising similarities of the optical conductivity and Raman spectra for the one-dimensional β\beta-type phases and the two-dimensional α\alpha-type ones such as the well-known α\alpha^\prime-NaV_2O_5NaV\_2O\_5 system

    Party finance reform as constitutional engineering? The effectiveness and unintended consequences of party finance reform in France and Britain

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    In both Britain and France, party funding was traditionally characterized by a laissez faire approach and a conspicuous lack of regulation. In France, this was tantamount to a 'legislative vacuum'. In the last two decades, however, both countries have sought to fundamentally reform their political finance regulation regimes. This prompted, in Britain, the Political Parties, Elections and Referendums Act 2000, and in France a bout of 'legislative incontinence' — profoundly transforming the political finance regime between 1988 and 1995. This article seeks to explore and compare the impacts of the reforms in each country in a bid to explain the unintended consequences of the alternative paths taken and the effectiveness of the new party finance regime in each country. It finds that constitutional engineering through party finance reform is a singularly inexact science, largely due to the imperfect nature of information, the limited predictability of cause and effect, and the constraining influence of non-party actors, such as the Constitutional Council in France, and the Electoral Commission in Britain

    honeybee workers exhibit conserved molecular responses to diverse pathogens

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    Background Organisms typically face infection by diverse pathogens, and hosts are thought to have developed specific responses to each type of pathogen they encounter. The advent of transcriptomics now makes it possible to test this hypothesis and compare host gene expression responses to multiple pathogens at a genome-wide scale. Here, we performed a meta-analysis of multiple published and new transcriptomes using a newly developed bioinformatics approach that filters genes based on their expression profile across datasets. Thereby, we identified common and unique molecular responses of a model host species, the honey bee (Apis mellifera), to its major pathogens and parasites: the Microsporidia Nosema apis and Nosema ceranae, RNA viruses, and the ectoparasitic mite Varroa destructor, which transmits viruses. Results We identified a common suite of genes and conserved molecular pathways that respond to all investigated pathogens, a result that suggests a commonality in response mechanisms to diverse pathogens. We found that genes differentially expressed after infection exhibit a higher evolutionary rate than non- differentially expressed genes. Using our new bioinformatics approach, we unveiled additional pathogen-specific responses of honey bees; we found that apoptosis appeared to be an important response following microsporidian infection, while genes from the immune signalling pathways, Toll and Imd, were differentially expressed after Varroa/virus infection. Finally, we applied our bioinformatics approach and generated a gene co-expression network to identify highly connected (hub) genes that may represent important mediators and regulators of anti-pathogen responses. Conclusions Our meta-analysis generated a comprehensive overview of the host metabolic and other biological processes that mediate interactions between insects and their pathogens. We identified key host genes and pathways that respond to phylogenetically diverse pathogens, representing an important source for future functional studies as well as offering new routes to identify or generate pathogen resilient honey bee stocks. The statistical and bioinformatics approaches that were developed for this study are broadly applicable to synthesize information across transcriptomic datasets. These approaches will likely have utility in addressing a variety of biological questions

    The virulent, emerging genotype B of Deformed wing virus is closely linked to overwinter honeybee worker loss

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    Bees are considered to be threatened globally, with severe overwinter losses of the most important commercial pollinator, the Western honeybee, a major concern in the Northern Hemisphere. Emerging infectious diseases have risen to prominence due to their temporal correlation with colony losses. Among these is Deformed wing virus (DWV), which has been frequently linked to colony mortality. We now provide evidence of a strong statistical association between overwintering colony decline in the field and the presence of DWV genotype-B (DWV-B), a genetic variant of DWV that has recently been shown to be more virulent than the original DWV genotype-A. We link the prevalence of DWV-B directly to a quantitative measure of overwinter decline (workforce mortality) of honeybee colonies in the field. We demonstrate that increased prevalence of virus infection in individual bees is associated with higher overwinter mortality. We also observed a substantial reduction of infected colonies in the spring, suggesting that virus-infected individuals had died during the winter. Our findings demonstrate that DWV-B, plus possible A/B recombinants exhibiting DWV-B at PCR primer binding sites, may be a major cause of elevated overwinter honeybee loss. Its potential emergence in naïve populations of bees may have far-reaching ecological and economic impacts

    Widespread Wolbachia infection in terrestrial isopods and other crustaceans

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    Wolbachia bacteria are obligate intracellular alpha-Proteobacteria of arthropods and nematodes. Although widespread among isopod crustaceans, they have seldom been found in non-isopod crustacean species. Here, we report Wolbachia infection in fourteen new crustacean species. Our results extend the range of Wolbachia infections in terrestrial isopods and amphipods (class Malacostraca). We report the occurrence of two different Wolbachia strains in two host species (a terrestrial isopod and an amphipod). Moreover, the discovery of Wolbachia in the goose barnacle Lepas anatifera (subclass Thecostraca) establishes Wolbachia infection in class Maxillopoda. The new bacterial strains are closely related to B-supergroup Wolbachia strains previously reported from crustacean hosts. Our results suggest that Wolbachia infection may be much more widespread in crustaceans than previously thought. The presence of related Wolbachia strains in highly divergent crustacean hosts suggests that Wolbachia endosymbionts can naturally adapt to a wide range of crustacean hosts. Given the ability of isopod Wolbachia strains to induce feminization of genetic males or cytoplasmic incompatibility, we speculate that manipulation of crustacean-borne Wolbachia bacteria might represent potential tools for controlling crustacean species of commercial interest and crustacean or insect disease vectors.This research was funded by a European Research Council Starting Grant (FP7/2007-2013 grant 260729 EndoSexDet) to RC and a Comité Mixte de Coopération Universitaire Franco-Tunisien grant to DB and FCC

    Emergence of Irrationality: Magnetization Plateaux in Modulated Hubbard Chains

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    Hubbard chains with periodically modulated coupling constants in a magnetic field exhibit gaps at zero temperature in their magnetic and charge excitations in a variety of situations. In addition to fully gapped situations (plateau in the magnetization curve and charge gap), we have shown [cond-mat/9908398] that plateaux also appear in the presence of massless modes, leading to a plateau with a magnetization m whose value depends continuously on the filling n. Here we detail and extend the arguments leading to such doping-dependent magnetization plateaux. First we analyze the low-lying excitations using Abelian bosonization. We compute the susceptibility and show that due to the constraint of fixed n, it vanishes at low temperatures (thus leading to a magnetization plateau) even in the presence of one massless mode. Next we study correlation functions and show that one component of the superconducting order parameter develops quasi-long-range order on a doping-dependent magnetization plateau. We then use perturbation theory in the on-site repulsion U to compute the width of these plateaux up to first order in U. Finally, we compute groundstate phase diagrams and correlation functions by Lanczos diagonalization of finite clusters, confirming the presence of doping-dependent plateaux and their special properties

    Unexpected band gap increase in the Fe2VAl Heusler compound

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    Knowing the electronic structure of a material is essential in energy applications to rationalize its performance and propose alternatives. Materials for thermoelectric applications are generally small-gap semiconductors and should have a high figure of merit ZT. Even if the Fe2VAl Heusler compound has a decent ZT, its conductive nature (semi-metal or semiconductor) is not yet clarified especially at low temperature. In this paper, we focus our DFT calculations on the effect of temperature on the bandgap of Fe2VAl. In contrast to what is usually observed, we show that both the temperature increase and the formation of thermally-activated Al/V inversion defects (observed experimentally), open the bandgap. Such an unusual behavior is the key for reconciling all bandgap measurements performed on the Fe2VAl compound using a standard GGA functional and could be an efficient way for improving the thermoelectric properties of this family of materials.Comment: 10 pages, 5 figure
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