1,167 research outputs found
Estudio de la Curva de Crecimiento en la Gallina Utrerana
Utilizando el modelo de Gompertz se compararon las curvas de crecimiento de pollos de las tres variedades
de la raza Utrerana: La Utreana Negra, la Perdiz y la
Franciscana. El estudio se realizó alojando los animales
en cautividad en el Centro Agropecuario Provincial de la
Diputación de Córdoba.
Se observó que la variedad Franciscana alcanzó un mayor peso a la madurez con 2870.3 g, seguida de la varidad Negra y, finalmente, de la variedad Perdiz con 2504.7 y 2181.8 g., respectivamente.
En lo que respecta a la velocidad de crecimiento de la
raza, la variedad Franciscana mostró las mayores tasas de
crecimiento hasta el punto de inflexión, en tanto que los menores índices de crecimiento a partir de dicho punto lo obtuvo la variedad Perdiz.
El punto de inflexión se alcanzó a los 62.16, 59.31 y
60.82 días por este orden, para la variedad Franciscana,
Negra y Pediz. Los pesos en ese punto fueron de 1056.03g para la variedad Franciscana, 921.52 g para la Negra y
802.72 g para la Perdiz
Protective efficacy of catalytic bioscavenger, paraoxonase 1 against sarin and soman exposure in guinea pigs
Human paraoxonase 1 (PON1) has been portrayed as a catalytic bioscavenger which can hydrolyze large amounts of chemical warfare nerve agents (CWNAs) and organophosphate (OP) pesticides compared to the stoichiometric bioscavengers such as butyrylcholinesterase. We evaluated the protective efficacy of purified human and rabbit serum PON1 against nerve agents sarin and soman in guinea pigs. Catalytically active PON1 purified from human and rabbit serum was intravenously injected to guinea pigs, which were 30 min later exposed to 1.2 × LCt50 sarin or soman using a microinstillation inhalation exposure technology. Pre-treatment with 5 units of purified human and rabbit serum PON1 showed mild to moderate increase in the activity of blood PON1, but significantly increased the survival rate with reduced symptoms of CWNA exposure. Although PON1 is expected to be catalytic, sarin and soman exposure resulted in a significant reduction in blood PON1 activity. However, the blood levels of PON1 in pre-treated animals after exposure to nerve agent were higher than that of untreated control animals. The activity of blood acetylcholinesterase and butyrylcholinesterase and brain acetylcholinesterase was significantly higher in PON1 pre-treated animals and were highly correlated with the survival rate. Blood O2 saturation, pulse rate and respiratory dynamics were normalized in animals treated with PON1 compared to controls. These results demonstrate that purified human and rabbit serum PON1 significantly protect against sarin and soman exposure in guinea pigs and support the development of PON1 as a catalytic bioscavenger for protection against lethal exposure to CWNAs
The Electromagnetic Counterpart of the Binary Neutron Star Merger LIGO/VIRGO GW170817. V. Rising X-ray Emission from an Off-Axis Jet
We report the discovery of rising X-ray emission from the binary neutron star
(BNS) merger event GW170817. This is the first detection of X-ray emission from
a gravitational-wave source. Observations acquired with the Chandra X-ray
Observatory (CXO) at t~2.3 days post merger reveal no significant emission,
with L_x<=3.2x10^38 erg/s (isotropic-equivalent). Continued monitoring revealed
the presence of an X-ray source that brightened with time, reaching L_x\sim
9x10^39 erg/s at ~15.1 days post merger. We interpret these findings in the
context of isotropic and collimated relativistic outflows (both on- and
off-axis). We find that the broad-band X-ray to radio observations are
consistent with emission from a relativistic jet with kinetic energy
E_k~10^49-10^50 erg, viewed off-axis with theta_obs~ 20-40 deg. Our models
favor a circumbinary density n~ 0.0001-0.01 cm-3, depending on the value of the
microphysical parameter epsilon_B=10^{-4}-10^{-2}. A central-engine origin of
the X-ray emission is unlikely. Future X-ray observations at
days, when the target will be observable again with the CXO, will provide
additional constraints to solve the model degeneracies and test our
predictions. Our inferences on theta_obs are testable with gravitational wave
information on GW170817 from Advanced LIGO/Virgo on the binary inclination.Comment: 7 Pages, 4 Figures, ApJL, In Press. Keywords: GW170817, LV
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New charge-transfer states in blends of ZnPC with F8ZnPC
With the aim of pushing the knowledge and understanding on mixed films of organic semiconductors forward, blends of ZnPC and F8ZnPC in different ratios are manufactured. The films have a polycrystalline structure, as indicated by electron diffraction profiles and infrared-spectroscopy. Photoluminescence data show completely different spectra for the blends, compared to the pure materials, which can be ascribed to the suppressing of excimer formation and the appearance of a new charge-transfer excitation between the two different molecules in the blends. This new excitation can also be seen in optical absorption. Momentum dependent measurements of the electronic excitations by electron energy-loss spectroscopy confirm the localized character of the new charge-transfer excitation in the blends. Our experimental data help understand the important issue of donor/acceptor coupling in organic semiconductors
Studies on immunocytochemical localization of inhibin-like material in human prostatic tissue: comparison of its distribution in normal, benign and malignant prostates.
A specific antiserum has been generated against inhibin-like material (ILM) of prostatic origin. Using the immunoperoxidase technique, localization of ILM has been examined in a total of 114 prostates including normal (4 specimens), malignant (46) and hyperplastic (55) tissues. ILM positive immunocytochemical reactions were confined to the cytoplasm and not the nucleus of the prostatic acinar cells in the three categories of prostate, whereas the stroma showed negative reactions. The intensity of positive reactions decreased in the following order: Hyperplasia, incidental and moderately differentiated carcinomas, poorly differentiated carcinomas, whereas metaplasia and granulomatous prostatitis gave negative reactions for ILM. Using this experimental protocol, 200 non-prostatic tissue were found to be completely negative, demonstrating the specificity of the test for prostatic epithelium. These findings indicate a potential use of ILM as a marker of prostatic tissue
The Electromagnetic Counterpart of the Binary Neutron Star Merger LIGO/VIRGO GW170817. VII. Properties of the Host Galaxy and Constraints on the Merger Timescale
We present the properties of NGC 4993, the host galaxy of GW170817, the first
gravitational wave (GW) event from the merger of a binary neutron star (BNS)
system and the first with an electromagnetic (EM) counterpart. We use both
archival photometry and new optical/near-IR imaging and spectroscopy, together
with stellar population synthesis models to infer the global properties of the
host galaxy. We infer a star formation history peaked at Gyr ago,
with subsequent exponential decline leading to a low current star formation
rate of 0.01 M yr, which we convert into a binary merger
timescale probability distribution. We find a median merger timescale of
Gyr, with a 90% confidence range of Gyr. This
in turn indicates an initial binary separation of R,
comparable to the inferred values for Galactic BNS systems. We also use new and
archival images to measure a projected offset of
the optical counterpart of kpc (0.64) from the center of NGC 4993
and to place a limit of mag on any pre-existing emission,
which rules out the brighter half of the globular cluster luminosity function.
Finally, the age and offset of the system indicates it experienced a modest
natal kick with an upper limit of km s. Future GWEM
observations of BNS mergers will enable measurement of their population delay
time distribution, which will directly inform their viability as the dominant
source of -process enrichment in the Universe.Comment: 9 Pages, 3 Figures, 2 Tables, ApJL, In Press. Keywords: GW170817, LV
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Oxygen-blown gasification combined cycle: Carbon dioxide recovery, transport, and disposal
This project emphasizes CO2-capture technologies combined with integrated gasification combined-cycle (IGCC) power systems, CO2 transportation, and options for the long-term sequestration Of CO2. The intent is to quantify the CO2 budget, or an ``equivalent CO2`` budget, associated with each of the individual energy-cycle steps, in addition to process design capital and operating costs. The base case is a 458-MW (gross generation) IGCC system that uses an oxygen-blown Kellogg-Rust-Westinghouse (KRW) agglomerating fluidized-bed gasifier, bituminous coal feed, and low-pressure glycol sulfur removal, followed by Claus/SCOT treatment, to produce a saleable product. Mining, feed preparation, and conversion result in a net electric power production for the entire energy cycle of 411 MW, with a CO2 release rate of 0.801 kg/kV-Whe. For comparison, in two cases, the gasifier output was taken through water-gas shift and then to low-pressure glycol H2S recovery, followed by either low-pressure glycol or membrane CO2 recovery and then by a combustion turbine being fed a high-hydrogen-content fuel. Two additional cases employed chilled methanol for H2S recovery and a fuel cell as the topping cycle, with no shift stages. From the IGCC plant, a 500-km pipeline takes the CO2 to geological sequestering. For the optimal CO2 recovery case, the net electric power production was reduced by 37.6 MW from the base case, with a CO2 release rate of 0.277 kg/kWhe (when makeup power was considered). In a comparison of air-blown and oxygen-blown CO2-release base cases, the cost of electricity for the air-blown IGCC was 56.86 mills/kWh, while the cost for oxygen-blown IGCC was 58.29 mills/kWh. For the optimal cases employing glycol CO2 recovery, there was no clear advantage; the cost for air-blown IGCC was 95.48 mills/kWh, and the cost for the oxygen-blown IGCC was slightly lower, at 94.55 mills/kWh
Advancing Glitch Classification in Gravity Spy: Multi-view Fusion with Attention-based Machine Learning for Advanced LIGO's Fourth Observing Run
The first successful detection of gravitational waves by ground-based
observatories, such as the Laser Interferometer Gravitational-Wave Observatory
(LIGO), marked a revolutionary breakthrough in our comprehension of the
Universe. However, due to the unprecedented sensitivity required to make such
observations, gravitational-wave detectors also capture disruptive noise
sources called glitches, potentially masking or appearing as gravitational-wave
signals themselves. To address this problem, a community-science project,
Gravity Spy, incorporates human insight and machine learning to classify
glitches in LIGO data. The machine learning classifier, integrated into the
project since 2017, has evolved over time to accommodate increasing numbers of
glitch classes. Despite its success, limitations have arisen in the ongoing
LIGO fourth observing run (O4) due to its architecture's simplicity, which led
to poor generalization and inability to handle multi-time window inputs
effectively. We propose an advanced classifier for O4 glitches. Our
contributions include evaluating fusion strategies for multi-time window
inputs, using label smoothing to counter noisy labels, and enhancing
interpretability through attention module-generated weights. This development
seeks to enhance glitch classification, aiding in the ongoing exploration of
gravitational-wave phenomena
Hyperbaric Oxygen Therapy Facilitates Healing of Chronic Foot Ulcers in Patients With Diabetes
OBJECTIVE: Chronic diabetic foot ulcers are a source of major concern for both patients and health care systems. The aim of this study was to evaluate the effect of hyperbaric oxygen therapy (HBOT) in the management of chronic diabetic foot ulcers. RESEARCH DESIGN AND METHODS: The Hyperbaric Oxygen Therapy in Diabetics with Chronic Foot Ulcers (HODFU) study was a randomized, single-center, double-blinded, placebo-controlled clinical trial. The outcomes for the group receiving HBOT were compared with those of the group receiving treatment with hyperbaric air. Treatments were given in a multi-place hyperbaric chamber for 85-min daily (session duration 95 min), five days a week for eight weeks (40 treatment sessions). The study was performed in an ambulatory setting. RESULTS: Ninety-four patients with Wagner grade 2, 3, or 4 ulcers, which had been present for >3 months, were studied. In the intention-to-treat analysis, complete healing of the index ulcer was achieved in 37 patients at 1-year of follow-up: 25/48 (52%) in the HBOT group and 12/42 (29%) in the placebo group (P = 0.03). In a sub-analysis of those patients completing >35 HBOT sessions, healing of the index ulcer occurred in 23/38 (61%) in the HBOT group and 10/37 (27%) in the placebo group (P = 0.009). The frequency of adverse events was low. CONCLUSIONS: The HODFU study showed that adjunctive treatment with HBOT facilitates healing of chronic foot ulcers in selected patients with diabetes
Cues and knowledge structures used by mental-health professionals when making risk assessments
Background: Research into mental-health risks has tended to focus on epidemiological approaches and to consider pieces of evidence in isolation. Less is known about the particular
factors and their patterns of occurrence that influence clinicians’ risk judgements in practice.
Aims: To identify the cues used by clinicians to make risk judgements and to explore how these combine within clinicians’ psychological representations of suicide, self-harm, self-neglect, and harm to others.
Method: Content analysis was applied to semi-structured interviews conducted with 46 practitioners from various mental-health disciplines, using mind maps to represent the
hierarchical relationships of data and concepts.
Results: Strong consensus between experts meant their knowledge could be integrated into a single hierarchical structure for each risk. This revealed contrasting emphases between data and concepts underpinning risks, including: reflection and forethought for suicide; motivation
for self-harm; situation and context for harm to others; and current presentation for self-neglect.
Conclusions: Analysis of experts’ risk-assessment knowledge identified influential cues and their relationships to risks. It can inform development of valid risk-screening decision support systems that combine actuarial evidence with clinical expertise
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