Osteoartropatia hipertrófica associada a linfoepitelioma de nasofaringe: relato de caso

Malignant neoplasms of the nasopharynx are very rare and has two peaks of incidence: below the age of 30, and between the 4th and 5th decade of life. It is, however, uncommon after the 60 years of age. In rare cases, some patients may present, in the form of paraneoplastic syndrome, hypertrophic osteoarthropathy (HOA). In this case report, we describe a case of HOA from lymphoepithelioma of the nasopharynx in a 77-year-old male patient, representing an extremely unusual condition.Neoplasias malignas de nasofaringe são muito raras e apresentam dois picos de incidência: antes dos30 anos e entre a 4ª e 5ª década de vida. No entanto, é incomum após os 60 anos de idade. Em raroscasos, alguns pacientes apresentam na forma de síndrome paraneoplásica a Osteoartropia Hipertrófica(OAH). Este relato de caso, nós descrevemos um caso de OAH associada a linfoepitelioma denasofaringe em um paciente de 77 anos, representando um condição extremamente incomum

Efficacy of beta-blocker therapy in symptomatic athletes with exercise-induced intra-ventricular gradients

<p>Abstract</p> <p>Background</p> <p>Upright exercise stress echocardiography (SE) induces significant intraventricular gradient (IVG) and systolic anterior motion (SAM) in a large proportion of symptomatic athletes, who may therefore benefit from a negative inotropic therapy.</p> <p>The purpose of the present study was to assess the effect of chronic oral β blocker therapy on the occurrence of exercise-induced IVG and mitral valve SAM, in symptomatic athletes.</p> <p>Methods</p> <p>We enrolled 35 symptomatic athletes (age = 23 ± 11 years) with IVG (>30 mmHg) during SE off therapy. All repeated SE on chronic oral beta-blocker therapy (atenolol up to 50 mg, bisoprolol up to 10 mg, or metoprolol up to 100 mg daily according to physician-driven choice).</p> <p>Results</p> <p>On therapy, there was during SE a reduction in IVG (35 off vs 17 on beta blocker, p < 0.01), decrease of IVG (102 ± 34 mmHg off vs 69 ± 24 mmHg on beta blocker, p < 0.01), peak heart rate (178 ± 15 bpm off vs 157 ± 9 bpm on beta blocker), SAM (24 off vs 9 on beta blocker, p < 0.001), symptoms during SE (17 off vs 2 on beta blocker p < 0.001), ST segment depression (13 off vs 2 on beta blocker, p < 0.001).</p> <p>Conclusions</p> <p>In athletes with positive screening on medical evaluation for sports practice and IVG on exertion, treatment with oral beta blockers improved symptoms in the large majority of patients. Symptomatic benefit was mirrored by objective evidence of improvement of echocardiographic signs of obstruction (IVG and SAM) and reduction of ischemia-like electrocardiographic changes.</p

Prevalência de anticorpos contra o vírus da hepatite B em população urbana do nordeste brasileiro

A sample of 1,288 inhabitants of Salvador, Bahia, Brazil, were submitted to the determination of anti-HBs using radioimmunoassay procedure, and analysed according to age, sex and income. Overall prevalence of anti-HBs was 11,8%. ranging from 6,7% among children aged less than three years old to 26,1% among those aged 30 years and older. Males presented prevalence of anti-HBs similar to female individuals, and those with a higher income showed frequencies of anti-HBs greater than those with a lower income level. The following conclusions were drawn: The high prevalence of anti-HBs observed among children suggests early contact with hepatitis B virus, possibly due to vertical transmission and intrafamiliar dissemination of the disease; the frequency of anti-HBs increases with age; the lower prevalence of anti-HBs among those with low income suggests that this group may present higher prevalence of carriers of the hepatitis B virus surface antigen.Um grupo de 1.288 indivíduos, residentes em Salvador, Bahia, Brasil, foi examinado para a determinação de anti-HBs, utilizando-se a técnica do radioimunoensaio. Os resultados foram analisados de acordo com a idade, o sexo e o nível de renda. Uma prevalência de anti-HBs de 11,8% foi observada, variando de 6,7% nas crianças com idade inferior a três anos, a 26,1% para aqueles com idade superior a 30 anos. A prevalência de anti-HBs foi similar em indivíduos do sexo masculino e feminino. Aqueles com nível de renda mais alto tiberam prevalência de anti-HBs maior que o grupo de renda baixa. Dos resultados conclui-se: a alta prevalência de anti-HBs em crianças sugere o contato precoce com o vírus da hepatite B, possivelmente relacionado com a transmissão vertical e a disseminação intraíamiliar do vírus; a freqüência de anti-HBs aumentou com a idade; a baixa prevalência de anti-HBs entre aqueles com baixo nível sócio-econômico sugere que neste grupo pode ser alta a prevalência de portadores do vírus B da hepatite

Frontiers in occupational health and safety management

This Special Issue of the International Journal of Environmental Research and Public Health is devoted to the “Frontiers in Occupational Health and Safety Management” [...

Ageing at work: capacity for the work of ESTeSC teachers

Introduction: Aging does not necessarily mean a decrease in "ability to work" and that the eventual decline of certain skills related to increasing age are not generalizable, striking, or uniform and can be accelerated or delayed depending on the conditions of work, individuals and, above all, the types of attrition to which the worker is subjected. Objective: To evaluate the work ability index (WAI) of the professors of the School of Technology and Health of Coimbra (ESTeSC). Material and Methods: This study was an analytical observational and prospective cohort study. The respondents answered a questionnaire that assessed the WAI and the quality of life index (QLI). The results were evaluated in the IBM SPSS Statistics program through descriptive character tests and inference tests. Results: It was verified that an average value of 33.63 (7-49 scale) was identified for the work ability in the studied group, being this value belonging to the Moderate category. When correlating the age of workers with WAI and QLI, it was verified that there was no correlation (p> 0.05) between these factors. On the other hand, WAI was related to QLI, in which a correlation was observed (p<0,05), that is, the more satisfied they are with quality of life, the better the capacity for work. Conclusion: It was found that in the present study, aging does not cause a loss of capacity for work, nor does it influence the quality of life of workers. Since teachers' scores for WAI are in the Moderate category, it is necessary to implement health promotion strategies, such as practicing physical exercise or performing work-related gymnastics in the workplace.info:eu-repo/semantics/publishedVersio

Signs Workshop: the importance of natural gestures in the promotion of early communication skills of children with developmental disabilities

This article emphasises the importance of natural gestures and describes the framework and the development process of the “Signs Workshop” CD-ROM, which is a multimedia application for the promotion of early communication skills of children with developmental disabilities. Signs Workshop CD-ROM was created in the scope of Down’s Comm Project, which was financed by the Calouste Gulbenkian Foundation, and is the result of a partnership between UNICA (Communication and Arts Research Unit of the University of Aveiro) and the Portuguese Down Syndrome Association (APPT21/Differences).Calouste Gulbenkian Foundatio

Produção da Bananeira BRS Tropical sob aplicação de ácidos húmicos via fertirrigação.

A bananeira é uma planta que necessita de uma concentração razoável de nutrientes disponíveis no solo, para seu desenvolvimento e produção. Este trabalho teve como objetivo o efeito de diferentes doses de ácidos húmicos na produtividade da bananeira cv. BRS Tropical sob fertirrigação. O experimento foi desenvolvido em um Latossolo Amarelo na Embrapa Mandioca e Fruticultura usando a cultura da bananeira cv. BRS Tropical espaçada de 2,0 x 2,5 m, fertirrigada por microaspersão. O experimento seguiu um delineamento em blocos ao acaso com seis repetições onde os tratamentos consistiram de cinco doses de ácidos húmicos com aplicação mensal ao longo do ciclo. A dose de referencia (DR) equivaleu a 35L/ha/ciclo e os tratamentos foram: T1= 60%DR; T2 = 80%DR; T3 = DR; T4 = 120%DR e T5 = 140%DR e T6 = testemunha. As variáveis analisadas no momento da emissão foram altura da planta, diâmetro do pseudocaule, número de folhas e área foliar. Na colheita, foram avaliados número de folhas, pencas e frutos; diâmetro e comprimento do fruto central da segunda penca; produtividade de penca e do cacho. As análises de variância mostraram que não houve diferença significativa entre os tratamentos para as variáveis, exceto o número de pencas e a área foliar

Environmental stratification in the brazilian Cerrado on the yield and fiber quality of cotton genotypes.

Environmental stratification studies are important for the plant breeding, since they allow to adequately plan the experimental network. The objective of this work was to identify similar environments for cotton cultivation in the Brazilian Cerrado regarding yield and fiber quality. Nineteen field studies were carried out in a randomized complete block design with twelve genotypes and four replicates. Agronomic (cotton seed yield and fiber percentage) and technological traits (length, micronaire, fiber strength) were evaluated. These results indicate that there are six environments (PVA3, MON, SHE1, SIN, PPA e TRIN) in which the cotton trials should be installed as a matter of priority owing to the phenotypic response pattern obtained for the evaluated traits. The remaining 13 environments are similar to each other for all traits and can be summarized in strategic locations depending on the ease of installation of the trials.Título em português: Estratificação ambiental no Cerrado brasileiro sobre o rendimento e a qualidade da fibra dos genótipos de algodão

Exposição Acidental a Picada de Agulha. Protocolo de Actuação

A picada acidental por agulha em crianças e adolescentes provoca grande ansiedade aos pais e é causa de recurso aos serviços de urgência.A exposição acidental inclui a picada por agulha de seringa encontrada na comunidade. O risco de transmissão do vírus da hepatite B (VHB), C (VHC), vírus da imunodeficiência humana (VIH) e outros agentes é habitualmente baixo, no entanto é da responsabilidade do clínico informar e minimizar a possibilidade de ocorrer doença.As recomendações atuais referentes à profilaxia em crianças são baseadas no risco de transmissão e seroconversão após exposição ocupacional em adultos. No entanto, e apesar da escassez de dados, a exposição acidental a picada de agulha na idade pediátrica merece uma avaliação particular.Com o objetivo de definir uma política comum a todos os hospitais e garantir acesso a cuidados mais adequados a todas as crianças, os autores apresentam um protocolo de profilaxia após exposição acidental a picada de agulha em idade pediátrica

The Portuguese observatory on occupational psychosocial factors: contribution for public health

To achieve the goal of sustainable employment, considering the profile of the Portuguese working population (PWP), is needed a range of strategies to ensure long, productive, and sustainable careers allied with a better quality of working life, health, and wellbeing, but also with public health policies grounded on scientifically validated and reliable data. This is possible through a comprehensive working system approach that ensures workers will be mentally and physically able to remain at work by the balance between work demands and individual resources allied with public health policies transfer into the workplaces by organizations’ leadership and policy makers. The Portuguese Observatory on Occupational Factors (Popsy@Work) aims at addressing this global challenge by: i) digitally collecting psychosocial data on the PWP; ii) implementing and strengthening of a psychosocial occupational health surveillance digital system; iii) providing reference values for the PWP concerning Psychosocial Health; iv) Transferring to society knowledge and best practices; v) Raising awareness on the importance of psychosocial management in occupational settings based on science. Popsy@work is a digital platform that collects and aggregates psychosocial data analytically and creates a visualization hub adding value to data on the PWP and giving science back to society in a usable way, empowering workers, strengthening organizations and grounding public policies. Pospy@Work considers the development of strategic intelligence on levels and inequalities of psychosocial health and well-being in occupational settings by robust metrics and reference data. Creating opportunities for national policy dialogue on inequalities, including the psychosocial health of the PWP through collaboration with diverse sectors identifying and mapping subgroups of populations whose unmet needs require specific outreach measures