Status of direct and indirect dark matter searches

I review the current status of dark matter searches using direct, indirect and accelerator techniques. A detailed review of individual experiments is beyond the scope of these proceedings. I focus instead on the challenges (sometimes limitations) faced by each of the approaches, which is what make them complementary, and the reason we must ensure that they are developed concurrently.Comment: Proceedings of European Physical Society Conference on High Energy Physics - EPS-HEP2019, 10-17 July, 2019. Submitted to Proceedings of Scienc

Closing the Window on Strongly Interacting Dark Matter with IceCube

We use the recent results on dark matter searches of the 22-string IceCube detector to probe the remaining allowed window for strongly interacting dark matter in the mass range 10^4<m_X<10^15 GeV. We calculate the expected signal in the 22-string IceCube detector from the annihilation ofsuch particles captured in the Sun and compare it to the detected background. As a result, the remaining allowed region in the mass versus cross sectionparameter space is ruled out. We also show the expected sensitivity of the complete IceCube detector with 86 strings.Comment: 5 pages, 7 figures. Uppdated figures 2 and 3 (y-axis normalization and label) . Version accepted for publication in PR

Impact of nucleon matrix element uncertainties on the interpretation of direct and indirect dark matter search results

We study in detail the impact of the current uncertainty in nucleon matrix elements on the sensitivity of direct and indirect experimental techniques for dark matter detection. We perform two scans in the framework of the cMSSM: one using recent values of the pion-sigma term obtained from Lattice QCD, and the other using values derived from experimental measurements. The two choices correspond to extreme values quoted in the literature and reflect the current tension between different ways of obtaining information about the structure of the nucleon. All other inputs in the scans, astrophysical and from particle physics, are kept unchanged. We use two experiments, XENON100 and IceCube, as benchmark cases to illustrate our case. We find that the interpretation of dark matter search results from direct detection experiments is more sensitive to the choice of the central values of the hadronic inputs than the results of indirect search experiments. The allowed regions of cMSSM parameter space after including XENON100 constrains strongly differ depending on the assumptions on the hadronic matrix elements used. On the other hand, the constraining potential of IceCube is almost independent of the choice of these values.We thank the Kavli Institute for Theoretical Physics at UCSB and organizers of the Hunting for Dark Matter programme for their hospitality during the preparation of this manuscript. This research was supported in part by the National Science Foundation under Grant No. NSF PHY11-25915. R. RdA, is supported by the Ramon y Cajal program of the Spanish MICINN and also thanks the support of the Spanish MICINN's Consolider-Ingenio 2010 Programme under the grant MULTIDARK CSD2209-00064 and the Invisibles European ITN project (FP7-PEOPLE-2011-ITN, PITN-CA-2011-289442-INVISIBLES). The use of IFT-UAM High Performance Computing Service is gratefully acknowledged.Peer reviewe

Assessing the sensitivity of PINGU to effective dark matter-nucleon interactions

We calculate the sensitivity of next generation neutrino telescopes to the 28 (isoscalar and isovector) coupling constants defining the non-relativistic effective theory of (spin 1/2) dark matter (DM)-nucleon interactions. We take as a benchmark detector the proposed Precision IceCube Next Generation Upgrade (PINGU), although our results are valid for any other neutrino telescope of similar effective volume. We express PINGU's sensitivity in terms of $5\sigma$ sensitivity contours in the DM-mass - coupling constant plane, and compare our sensitivity contours with the 90% C.L. exclusion limits on the same coupling constants that we obtain from a reanalysis of the null result of current DM searches at IceCube/DeepCore. We find that PINGU can effectively probe not only the canonical spin-independent and spin-dependent DM-nucleon interactions, but also velocity-dependent or momentum-dependent interactions that generate coherently enhanced DM-nucleus scattering cross sections. We also find that PINGU's $5\sigma$ sensitivity contours are significantly below current IceCube/DeepCore 90% C.L. exclusion limits when $b\bar{b}$ is the leading DM annihilation channel. This result shows the importance of lowering the experimental energy threshold when probing models that generate soft neutrino energy spectra, and holds true independently of the assumed DM-nucleon interaction and for all DM masses tested here. When DM primarily annihilates into $\tau\bar{\tau}$, a PINGU-like detector will improve upon current exclusion limits for DM masses below $35$ GeV, independently of the assumed DM-nucleon interaction.Comment: 20 pages, 6 figures and 1 tabl

Diagnóstico: La Reforma Laboral y las políticas necesarias en el Perú. Entrevista a Alfonso de los Heros Pérez-Albela

El Derecho Laboral es una rama que ha generado mucha polémica en nuestro país, pues mientras  algunos  sectores  consideran que presenta una rigidez que limita al sector privado, otros consideran que es muy flexible y no protege adecuadamente al trabajador.En esta entrevista, el autor nos ilustra sobre la normativa laboral y su impacto a lo largo de los últimos años, desde las reformas laborales que se llevaron a cabo cuando ocupó la cartera del entonces Ministerio de Trabajo y Promoción Social hasta la aprobación de la reciente Ley del Servicio Civil

Targeting the orexin/hypocretin system for the treatment of neuropsychiatric and neurodegenerative diseases: from animal to clinical studies

Orexins (also known as hypocretins) are neuropeptides located exclusively in hypothalamic neurons that have extensive projections throughout the central nervous system and bind two different G protein-coupled receptors (OX1R and OX2R). Since its discovery in 1998, the orexin system has gained the interest of the scientific community as a potential therapeutic target for the treatment of different pathological conditions. Considering previous basic science research, a dual orexin receptor antagonist, suvorexant, was the first orexin agent to be approved by the US Food and Drug Administration to treat insomnia. In this review, we discuss and update the main preclinical and human studies involving the orexin system with several psychiatric and neurodegenerative diseases. This system constitutes a nice example of how basic scientific research driven by curiosity can be the best route to the generation of new and powerful pharmacological treatments

Constraints on Enhanced Dark Matter Annihilation from IceCube Results

Excesses on positron and electron fluxes measured by ATIC, and the PAMELA and Fermi--LAT telescopes can be explained by dark matter annihilation in our Galaxy. However, this requires large boosts on the dark matter annihilation rate. There are many possible enhancement mechanisms, such as the Sommerfeld effect or the existence of dark matter clumps in our halo. If enhancements on the dark matter annihilation cross section are taking place, the dark matter annihilation in the core of the Earth should also be enhanced. Here we use recent results from the IceCube 40-string configuration to probe generic enhancement scenarios. We present results as a function of the dark matter-proton interaction cross section, $\sigma_{\chi p}$ weighted by the branching fraction into neutrinos, $f_{\nu\bar{\nu}}$, as a function of a generic boost factor, $B_F$, which parametrizes the expected enhancement of the annihilation rate. We find that dark matter models which require annihilation enhancements of $\mathcal{O}(100)$ or more and that annihilate significantly into neutrinos are excluded as the explanation for these excesses. We also determine the boost range that can be probed by the full IceCube telescope.Comment: 6 pages, 3 figures; version accepted for publicatio

Including Systematic Uncertainties in Confidence Interval Construction for Poisson Statistics

One way to incorporate systematic uncertainties into the calculation of confidence intervals is by integrating over probability density functions parametrizing the uncertainties. In this note we present a development of this method which takes into account uncertainties in the prediction of background processes, uncertainties in the signal detection efficiency and background efficiency and allows for a correlation between the signal and background detection efficiencies. We implement this method with the Feldman & Cousins unified approach with and without conditioning. We present studies of coverage for the Feldman & Cousins and Neyman ordering schemes. In particular, we present two different types of coverage tests for the case where systematic uncertainties are included. To illustrate the method we show the relative effect of including systematic uncertainties the case of dark matter search as performed by modern neutrino tel escopes.Comment: 23 pages, 10 figures, replaced to match published versio

Measurement of negative particle multiplicity in S - Pb collisions at 200 GeV/c per nucleon with the NA36 TPC

A high statistics study of the negative multiplicity distribution from S-Pb collisions at 200 GeV/c per nucleon is presented. The NA36 TPC was used to detect charged particles; corrections are based upon the maximum entropy method.A high statistics study of the negative multiplicity distribution from S-Pb collisions at 200 GeV/c per nucleon is presented. The NA36 TPC was used to detect charged particles; corrections are based upon the maximum entropy method.A high statistics study of the negative particle multiplicity distribution from S–Pb collisions at 200 GeV/ c per nucleon is presented. The NA36 TPC was used to detect charged particles; corrections are based upon the maximum entropy method