El disfraz de varón en las comedias de Ana Caro (1590-1646)

Este trabajo tiene por objetivo estudiar el motivo del disfraz de varón en dos comedias del siglo XVII, ambas compuestas por la dramaturga Ana Caro (1590-1646). Parte del estudio de la vida y obra de la autora Ana Caro. La incógnita que rodea sus orígenes es todavía mayor que la que rodea su producción literaria, de la cual se conservan relaciones, poesía circunstancial y teatro, género en el que se centra el trabajo. Junto a la figura de Ana Caro, se investiga la relación de la mujer con el teatro áureo como espectadora, actriz y autora. En cuanto al motivo del disfraz de varón, a mediados del siglo XVI es cuando aparece en el panorama teatral, pero sus orígenes se remontan a la literatura latina con el mito de las amazonas y se desarrolla con la figura de la dama guerrera caballeresca, precedente inmediato de la disfrazada de varón. El trabajo se centra en el análisis de la comedia Valor, agravio y mujer, en la cual el disfraz de varón recae sobre el personaje de Leonor, quien pasa a ser Leonardo. En segundo lugar, en la comedia El conde Partinuplés, inspirada en el relato en el relato caballeresco breve francés del mismo título y en cuya trama la autora introduce diversas modificaciones; en este caso el análisis del motivo del disfraz de varón recae en tres personajes: Rosaura, el conde Partinuplés y Lisbella

Focusing on Quality Patient Care in the New Global Subsidy for Malaria Medicines

Tido von Schoen-Angerer and colleagues discuss the new Affordable Medicines Facility for malaria (AMFm), which subsidizes and facilitates access to artemisinin-based combination therapy, and what mechanisms are needed to ensure it stays focused on quality patient care

Low and high dietary folic acid levels perturb postnatal cerebellar morphology in growing rats

The brain is particularly sensitive to folate metabolic disturbances, because methyl groups are critical for brain functions. This study aimed to investigate the effects of different dietary levels of folic acid (FA) on postnatal cerebellar morphology, including the architecture and organisation of the various layers. A total of forty male OFA rats (a Sprague–Dawley strain), 5 weeks old, were classified into the following four dietary groups: FA deficient (0 mg/kg FA); FA supplemented (8 mg/kg FA); FA supra-supplemented (40 mg/kg FA); and control (2 mg/kg FA) (all n 10 per group). Rats were fed ad libitum for 30 d. The cerebellum was quickly removed and processed for histological and immunohistochemical analysis. Slides were immunostained for glial fibrillary acidic protein (to label Bergmann glia), calbindin (to label Purkinje cells) and NeuN (to label post-mitotic neurons). Microscopic analysis revealed two types of defect: partial disappearance of fissures and/or neuronal ectopia, primarily in supra-supplemented animals (incidence of 80 %, P≤0·01), but also in deficient and supplemented groups (incidence of 40 %, P≤0·05), compared with control animals. The primary fissure was predominantly affected, sometimes accompanied by defects in the secondary fissure. Our findings show that growing rats fed an FA-modified diet, including both deficient and supplemented diets, have an increased risk of disturbances in cerebellar corticogenesis. Defects caused by these diets may have functional consequences in later life. The present study is the first to demonstrate that cerebellar morphological defects can arise from deficient, as well as high, FA levels in the diet

Highly hydrophobic organic coatings based on organopolysilazanes and silica nanoparticles: evaluation of environmental degradation

Hydrophobic coatings have potential applications in various fields, including for corrosion and weathering protection. In this study, we investigated the use of organopolysilazanes (OPSZs) combined with hydrophobic nanoparticles (NPs) on steel as a substrate to obtain hydrophobic coatings. The coatings were characterized using various techniques, and their hydrophobic properties and corrosion and weathering resistance were evaluated under near-shore marine conditions with high salinity, humidity and UV radiation. Our results show that the coatings exhibited excellent hydrophobic properties and significantly improved corrosion and weathering resistance compared to an uncoated steel and a pristine polymer. These findings suggest that the developed coatings have the potential to provide protection against corrosion for atmospheric and splash exposures in marine environments.This research was funded by the Ministry of Science, Innovation and Universities of Spain, through the Torres Quevedo Program, grant number PTQ2018-009743

Analysis of extreme rainfall in the Ebre Observatory (Spain)

The relationship between maximum rainfall rates for time intervals between 5 min and 24 h has been studied from almost a century (1905-2003) of rainfall data registered in the Ebre Observatory (Tarragona, Spain). Intensity-duration-frequency (IDF) curves and their master equation for every return period in the location have been obtained, as well as the probable maximum precipitation (PMP) for all the considered durations. In particular, the value of the 1-day PMP has resulted to be 415 mm, very similar to previous estimations of this variable for the same location. Extreme rainfall events recorded in this period have been analyzed and classified according to their temporal scale. Besides the three main classes of cases corresponding to the main meteorological scales, local, mesoscale, and synoptic, a fourth group constituted by complex events with high-intensity rates for a large range of durations has been identified also, indicating the contribution of different scale meteorological processes acting together in the origin of the rainfall. A weighted intensity index taking into account the maximum rainfall rate in representative durations of every meteorological scale has been calculated for every extreme rainfall event in order to reflect their complexity

Analysis of extreme rainfall in the Ebre Observatory (Spain)

The final publication is available at Springer via http://dx.doi.org/10.1007/s00704-015-1476-0Relationship between maximum rainfall rates for time intervals between 5 minutes and 24 hours has been studied from almost a century (1905-2003) of rainfall data registered in the Ebre Observatory (Tarragona, Spain). Intensity-duration-frequency (IDF) curves and its master equation for every return period in the location have been obtained, as well as the probable maximum precipitation (PMP) for all the considered durations. In particular, the value of the 1-day PMP has resulted 415 mm, very similar to previous estimations of this variable for the same location. Extreme rainfall events recorded in this period have been analyzed and classified according to their temporal scale. Besides the three main classes of cases corresponding to the main meteorological scales, local, mesoscale and synoptic, a fourth group constituted by complex events with high intense rates for a large range of durations has been identified also, indicating the contribution of different scale meteorological processes acting together in the origin of the rainfall. A weighted intensity index taking into account the maximum rainfall rate in representative durations of every meteorological scale has been calculated for every extreme rainfall event in order to reflect their complexity.Peer ReviewedPostprint (published version

Analysis of synoptic patterns in relationship with severe rainfall events in the Ebre Observatory (Catalonia)

The study has obtained a classification of the synoptic patterns associated with a selection of extreme rain episodes registered in the Ebre Observatory between 1905 and 2003, showing a return period of not less than 10 years for any duration from 5 min to 24 h. These episodes had been previously classified in four rainfall intensity groups attending to their meteorological time scale. The synoptic patterns related to every group have been obtained applying a multivariable analysis to three atmospheric levels: sea-level pressure, temperature, and geopotential at 500 hPa. Usually, the synoptic patterns associated with intense rain in southern Catalonia are featured by low-pressure systems advecting warm and wet air from the Mediterranean Sea at the low levels of the troposphere. The configuration in the middle levels of the troposphere is dominated by negative anomalies of geopotential, indicating the presence of a low or a cold front, and temperature anomalies, promoting the destabilization of the atmosphere. These configurations promote the occurrence of severe convective events due to the difference of temperature between the low and medium levels of troposphere and the contribution of humidity in the lowest levels of the atmosphere.Peer ReviewedPostprint (author's final draft

Desarrollo de un espacio web de prácticas de neuroanatomía y embriología humanas

Presentamos dos proyectos que se relacionan, el primero con la mejora en las prácticas de neuroanatomía para alumnos de segundo de medicina, y el segundo con la enseñanza de la embriología humana, un proyecto bastante complejo del que presentamos aquí su inicio, pero que deseamos convertirlo a medio plazo en una asignatura virtual

Aula-Taller inclusiva de jardinería

En los últimos años, nuestra sociedad ha avanzado en la concienciación ciudadana y la búsqueda de soluciones para la integración del colectivo de personas con discapacidad física, sin embargo, el camino pendiente por recorrer en lo que a la discapacidad intelectual o psíquica se refiere es todavía largo. La universidad, como parte importante de la sociedad no puede obviar la necesidad de implicarse en formar a sus alumnos, no solo desde un punto de vista curricular, sino también en proporcionarles valores y destrezas que faciliten la convivencia de este tipo de personas. En este sentido, este proyecto pretende formar a alumnos de la Universidad Politécnica de Madrid (UPM) en competencias transversales y en habilidades sociales llevando a cabo el establecimiento de un jardín vertical con jóvenes con algún trastorno del espectro autista (TEA), en colaboración con la Asociación de personas con autismo ALEPH-TEA. La experiencia ha sido muy bien valorada por los alumnos, tanto en lo referente a la formación curricular recibida, como en valores sociales y humanos, y en desarrollo de competencias transversales. Este proyecto abre las puertas a seguir organizando actividades encaminadas a potenciar y mejorar la integración de personas con TEA y/o discapacidad intelectual en la sociedad

Molecular Analysis of Echovirus 13 Isolates and Aseptic Meningitis, Spain

Echovirus 13 (EV13), considered rare, was reported worldwide in 2000, mostly related to aseptic meningitis outbreaks. In Spain, 135 EV13 isolates were identified. The genetic relationships between 64 representative strains from Spain and other reported isolates from the United States, Germany, Italy, Japan, and Sweden were described by analyzing the partial sequence of the major capsid protein (VP1) gene. The strains from Spain were clearly identified as EV13 (79.5% similarity with the EV13 reference strain) and were grouped phylogenetically into two different clusters (by origination on either the Iberian Peninsula or Canary Islands). Isolates from Germany from 2000 clustered with the Canary Islands group. The isolates from other countries obtained before 2000 were genetically distant. Changes in EV13 coding sequence involved several differences in the C-terminal extreme of the VP1 protein. Part of the neutralizing antigenic site III has been described in this genome region in poliovirus and swine vesicular disease virus