2,258 research outputs found
A Novel Cyber Resilience Framework – Strategies and Best Practices for Today's Organizations
Cyber resilience refers to an organization's ability to maintain its essential functions, services despite cyber-attacks and swiftly recover from any disruptions. It involves proactive measures like gathering threat intelligence and managing risks, as well as reactive measures such as incident response planning, data backup and recovery. To achieve cyber resilience, organizations must implement robust cyber security measures, regularly update their incident response plans, and educate employees on safe online practices. Furthermore, having a comprehensive backup and recovery strategy in place is crucial to swiftly restore critical systems and data in the event of an attack. Overall, the proposed framework emphasizes cyber resilience as a continuous and proactive approach for managing cyber security risks and safeguarding against the growing threat of cyber-attacks
Prediction of sales using Big data analytics
Social media is a main source of collecting big-data. Data analysis converting their bigger data to smart data. Smart data is acquired with the help of Apache Flume, Apache hive and Apache HDFS, smart data increase the sales of Marketing industry. It helps product owner to analyze people’s opinion about their product and consumer can analyze the reviews of product before purchase. If tweets came along with Location, data analyzed based on the location
Multi-Walled Carbon Nanotubes Percolation Network Enhanced the Performance of Negative Electrode for Lead-Acid Battery
The discharge performance of lead-acid battery is improved by adding multi-walled carbon nanotubes (MWCNTs) as an alternate
conductive additive in Negative Active Mass (NAM).We report thatMWCNTs added to the negative electrode, exhibits high capacity,
excellent cycling performances at 10-h rate, high rate partial state of charge (HRPSoC) cycling and various rates of discharge. It
significantly reduces the irreversible lead sulfate on the NAM, increases the active material utilization and improves the electrode
performance. The improvement of capacity and cyclic performance of the cell is attributed to the nanoscale dimension of the
MWCNTs as additive. Subsequent characterization using high resolution transmission electron microscopy and scanning electron
microscopy were carried out to understand the influence of MWCNTs on the negative electrode of lead-acid battery
Nanohydroxyapatite-reinforced chitosan composite hydrogel for bone tissue repair in vitro and in vivo
Studies on clustering of chilli (Capsicum annum L.) genotypes based on genetic distance
Mahalanobis' D2 statistics was used to analyse forty-five chilli (Capsicum annum L.) genotypes based on eighteen characters in order to pick out supreme potential parents for hybridization. Based on D2 values, the genotypes were divided into eleven groups with extreme divergence. Cluster I had the majority of genotypes (sixteen), whereas the fewest genotypes were identified in clusters VII, VIII, X and XI (one). Cluster XI had the greatest distance within the cluster. Clusters V and XI had the maximum generalized distance between them, followed by clusters VII and XI, clusters IV and VII, clusters IV and V and clusters II and XI. This suggests that the genotypes in these groups had more genetic variation. Following cluster VII and VIII, cluster V showed the highest cluster mean for green, dry fruit yield (846g and 95.50g) and several yield-related features. At clusters I, II and VI, no observation for high cluster means but had fair trait performance. It may be suggested to directly advance the genotypes from clusters V, VII, VII in hybridization to obtain unique recombinants
ANTAGONISTIC POTENTIAL OF FLUORESCENT Pseudomonas AND ITS IMPACT ON GROWTH OF TOMATO CHALLENGED WITH PHTOPATHOGENS
This study focused on the antagonistic potential of fluorescent
Pseudomonas in vitro, and its inoculation effect on growth
performance of Lycopersicon esculentum in Fusarium oxysporum and
Rhizoctonia solani infested soil. Biochemical characteristics of
fluorescent Pseudomonas showed that all ten isolates were positive to
catalase, amylase, gelatinase and siderophore production. While three
isolates (Pf5, Pf6 and Pf9) were oxidase positive, nine isolates (Pf1,
Pf2, Pf3, Pf4, Pf6, Pf7, Pf8, Pf9, and Pf10) were tolerant to 6.5%
NaCl. Isolates Pf5 and Pf6 were resistant to all the test antibiotics;
in contrast, the remaining eight isolates responded differently to
different antibiotics. Isolates Pf5 and Pf6 were antagonistic against
14 bacterial species, and two pathogenic fungi (F. oxysporum and R.
solani). Inoculation with fulorescent Pseudomonas Pf5 induced a
significant increase in root and shoot length, and dry weight.
Treatment of plants with either F. oxysporum or R. solani drastically
reduced the root and shoot length and dry weight of the plant. However,
in the presence of fluorescent Pseudomonas the adverse effect of the
pathogens on growth of L. esculentum was alleviated.Cette \ue9tude a port\ue9 sur le potentiel antagonistique du
Pseudomonas fluorescent, in vitro et les effets de son inoculation
sur la performance en croissance du Lycopersicon esculentum dans le
sol infest\ue9 par le Fusarium oxysporum et le Rhizoctonia solani
. Les caract\ue9ristiques biochemiques du Pseudomonas fluorescent ont
montr\ue9 que tous les dix isolats \ue9taient positives eu
\ue9gard \ue0 la production de catalase, amylase, g\ue9latinase
et sid\ue9rophore. Alors que trois isolats (Pf5, Pf6 and Pf9)
\ue9taient oxidase positifs, neuf isolats (Pf1, Pf2, Pf3, Pf4, Pf6,
Pf7, Pf8, Pf9, et Pf10) \ue9taient tolerant au 6.5% NaCl. Les isolats
Pf5 et Pf6 \ue9taient r\ue9sistants \ue0 tous les test
antibiotiques; au contraire, les huit isolats restants ont r\ue9pondu
diff\ue9remment aux diff\ue9rents antibiotiques. Les isolats Pf5 et
Pf6 \ue9taient antagonistiques contre 14 esp\ue8ces de
bact\ue9ries, et deux champignons pathogeniques (F. oxysporum et R.
solani). L\u2019inoculation avec Pseudomonas fulorescent Pf5 a induit
une augmentation significative des raciness et de la longueur des
tiges, ainsi que du poids sec. Le traitement de plants avec du F.
oxysporum ou du R. solani ont radicalement r\ue9duit la longueur des
raciness et tiges ainsi que le poids sec du plant. Cependant, en
pr\ue9sence du Pseudomonas fluorescent, l\u2019effet adverse du
pathog\ue8ne sur la croissance du L. esculentum \ue9tait
allevi\ue9
Agarala: A traditional fishing boat of Karnataka
Agarala boat or coracle is a traditional fishing boat used for estuarine and riverine fishing in Karnataka. These traditional
boats ensure sustainable fishing using eco-friendly fishing methods. The main fish species caught in these crafts are
Sillago sihama, Sphyraena obtusata, Mugil cephalus, Aries aries, Gerres filamentosus, Lutjanus argentimaculatus,
Leiognathus splendens, Cynoglossus macrostomus, Psettodes erumei, Platycephalus indicus, Etroplus suratensis,
Anodontostoma chacunda, Portunus pelagicus, P.sanguinolentus, Scylla serrata, Thryssa mystax, and Opisthopterus
tardoore. Fishing with agarala in the estuarine waters is largely at subsistence level and is carried out by a minor section of
the fishermen community. The following paper documents and reports for the first time, the use of such unique fishing
boats, in the Dakshina Kannada district, Karnataka. The main objective of the study was to explore the nature of crafts, the
unique design of the crafts used and types of fishes caught. Fishing in agarala provides a good source of income to the
fishermen using these simple, traditional environment friendly and cost effective crafts which make sustainable use of the
scarce fishery resources
Low vitamin B12 in pregnancy is associated with adipose derived circulating miRs targeting PPARγ and insulin resistance
Context:
Low vitamin B12 (B12) during pregnancy is associated with higher maternal obesity, insulin resistance(IR) and gestational diabetes(GDM). B12 is a key co-factor in 1-carbon metabolism.
Objective:
We hypothesize that B12 plays a role in epigenetic regulation by altering circulating miRNAs(miRs) during adipocyte differentiation and results in an adverse metabolic phenotype.
Design, settings and main-outcome measure:
Human pre-adipocyte cell-line(Chub-S7) were differentiated in various B12 concentrations: Control(500nM), LowB12(0.15nM) and NoB12(0nM). Maternal blood samples(n=91) and subcutaneous adipose tissue (SAT)(n=42) were collected at delivery. Serum B12, folate, lipids, plasma 1-carbon metabolites, miR profiling, miR expression and gene expression were measured.
Results:
Our in vitro model demonstrated that adipocytes in B12 deficient conditions accumulated more lipids, had higher triglyceride levels and increased gene expression of adipogenesis and lipogenesis. MiR array screening revealed differential expression of 133miRs involving several metabolic pathways (adjusted p<0.05). Altered miR expression were observed in 12miRs related to adipocyte differentiation and function in adipocytes. Validation of this data in pregnant women with low B12, confirmed increased expression of adipo/lipogenic genes and altered miRs in SAT, and altered levels of 11 of the 12miRs in circulation. After adjusting for other possible confounders, multiple regression analysis revealed an independent association of B12 with BMI (β: -0.264; 95% CI: -0.469, -0.058; p=0.013) and was mediated by four circulating miRs targeting PPARγ and IR.
Conclusions:
Low B12 levels in pregnancy alters adipose derived circulating miRs, which may mediate an adipogenic and IR phenotype leading to obesity
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