94 research outputs found

    The effect of oral rehydration solution and recommended home fluids on diarrhoea mortality

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    Background Most diarrhoeal deaths can be prevented through the prevention and treatment of dehydration. Oral rehydration solution (ORS) and recommended home fluids (RHFs) have been recommended since 1970s and 1980s to prevent and treat diarrhoeal dehydration. We sought to estimate the effects of these interventions on diarrhoea mortality in children aged <5 years

    Early life patterns of common infection: a latent class analysis

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    Early life infection has been implicated in the aetiology of many chronic diseases, most often through proxy measures. Data on ten infectious symptoms were collected by parental questionnaire when children were 6 months old as part of the Avon Longitudinal Study of Parents and Children, United Kingdom. A latent class analysis was used to identify patterns of infection and their relationship to five factors commonly used as proxies: sex, other children in the home, maternal smoking, breastfeeding and maternal education. A total of 10,032 singleton children were included in the analysis. Five classes were identified with differing infectious disease patterns and children were assigned to the class for which they had a highest probability of membership based on their infectious symptom profile: ‘general infection’ (n = 1,252, 12.5%), ‘gastrointestinal’ (n = 1,902, 19.0%), ‘mild respiratory’ (n = 3,560, 35.5%), ‘colds/ear ache’ (n = 462, 4.6%) and ‘healthy’ (n = 2,856, 28.5%). Females had a reduced risk of being in all infectious classes, other children in the home were associated with an increased risk of being in the ‘general infection’, ‘mild respiratory’ or ‘colds/ear ache’ class. Breastfeeding reduced the risk of being in the ‘general infection’ and ‘gastrointestinal’ classes whereas maternal smoking increased the risk of membership. Higher maternal education was associated with an increased risk of being in the ‘mild respiratory’ group. Other children in the home had the greatest association with infectious class membership. Latent class analysis provided a flexible method of investigating the relationship between multiple symptoms and demographic and lifestyle factors

    Fundusautofloureszenz als Diagnosetool in Patienten mit Retinitis Pigmentosa

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    THE EFFECT OF ATTACK ANGLE TO VORTEX SHEDDING PHENOMENON OF FLOW AROUND A SQUARE PRISM WITH A FLOW CONTROL ROD

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    WOS: 000290072700011In this study, the effect of attack angle on vortex shedding phenomena in the case of flow around the square prism as a bluff body and the circular rod which used as flow control component was experimentally investigated. While the value of attack angle equal to 0 degrees, the upstream control rod and square prism are in tandem arrangement to free stream. Experiments were conducted at Reynolds number of 1.0 x 10(4), for the diameter ratio of d/D=0.25, the attack angle between 0 degrees <= alpha <= 90 degrees, and the value of normalized distance between two prism LID is 1, 2, 3, and 4. The velocity measurements were conducted by means of constant temperature anemometer (CTA) as well as vortex shedding frequencies obtained by the spectral analysis of velocity-time history. Characteristics of the vortex formation region and location of flow attachments, reattachments, and separations were observed by means of the smoke-wire flow visualizations. At the angle of attack 0 degrees of the location L/D=2 and 3, the flow structure that possess high vorex shedding frequency which causes remarkable reductions on the drag force and significant increase in the heat transfer was obtained. This flow structure continous to decrease with increasing attack angle up to around 10 degrees. By further increasing of attack angle, the effect of flow control rod on vortex shedding frequency disappears completely

    Is a 2 : 1 Ratio of Standard Who Ors to Plain Water Effective in the Treatment of Moderate Dehydration

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    Increased amounts of plain water have been recommended ad libitum during rehydration treatment with oral rehydration solutions (ORS) in moderately dehydrated cases in order to decrease the hypertonicity of ORS. However, we could not encounter any study demonstrating its effectiveness objectively. In this study, moderately dehydrated children admitted to Hacettepe University Ihsan Dogramaci Children's Hospital Diarrheal Disease Training and Treatment Unit were administered either standard WHO ORS treatment or two parts of standard WHO ORS and one part of plain water alternately at a dose of 100 ml/kg, according to the period they were admitted to the center. The frequency of vomiting, stool purging rate, and unscheduled intravenous treatment rate of the two different regimens were compared. There were 51 children in the standard ORS group and 79 children in the 2 : I ratio ORS group. The admission characteristics of the children were similar. The children with a stool purging rate over one per hour during treatment was higher in the standard ORS group (29.4 vs. 15.2 per cent, p = 0.051), as well as the children with vomiting (56 vs. 30 per cent, p = 0.007). The children who required unscheduled intravenous treatment was also higher in the standard ORS group (20 vs. 14 per cent, p = 0.2). A regimen of two parts of WHO ORS and one part of plain water may be an alternative treatment for moderately dehydrated children with non-cholera diarrhea in areas where hypotonic ORS is not yet available.WoSScopu

    Relationship Between Physical, Environmental and Sociodemographic Factors and School Performance in Primary Schoolchildren

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    Poor primary school performance is a risk factor for low high-school and university graduation, as well as poverty in later life. In this case-control study, the relation between a variety of physical, environmental and sociodemographic factors, and primary school performance was investigated. Grade one students with good and poor school achievement, from different socioeconomic levels were studied. A questionnaire about the sociodemographic characteristics and child's medical history, together with a Child Behavior Checklist, was filled out by parents. Physical examination, visual and hearing screening were performed. Blood count and blood lead levels were determined. Wechsler Intelligence Scale for Children-Revised (WISC-R) was performed to determine the IQ. A total of 177 students participated in the study. Stepwise logistic regression revealed an independent positive relation between duration of study (OR, 2.69; Cl, 1.19-6.05; p = 0.016), maternal education (OR, 1.47; Cl, 1.14-1.87; p = 0.002), full scale score of WISC-R (OR, 1.08; Cl, 1.03-1.3; p = 0.002) and school performance. Multinomial logistic regression revealed that the risk of having a below average full scale WISC-R score was higher among children having a hearing loss, uncorrected vision loss, heating house with stove, cigarette smoking of both parents, and low paternal education (less than 8 years). The chance of having an above average full scale WISC-R score was lower among children whose either parent smoked cigarettes, height-for-age percentile was below 10, and maternal education was less than 8 years. Policies for increasing male and female education, growth monitoring, appropriate feeding (breastfeeding and weaning), well-baby and child followup and clean environment (indoor and outdoor) will not only promote the physical health but also promote the cognitive development of the new generations.WoSScopu

    Speech Delay In Toddlers: Are They Only "Late Talkers"?

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    Speech delay is prevalent in toddlers. Although some children with speech delay are able to catch up with their peers with time, the delay might be part of a broader condition such as global developmental delay, which requires specific diagnostic work-up. The current study aimed to present the demographic features, developmental profiles of the first 100 preschool-aged children who were seen at Hacettepe University Ihsan Dogramaci Children's Hospital-Developmental Pediatrics Unit with parental concern of speech delay. Moreover, risk factors associated with speech delay, possible diagnosis and intervention strategies are documented. Thirty-one of 100 children were diagnosed with autism spectrum disorder (ASD) and global developmental delay (GDD). The current study presented that 4 out of 5 toddlers exceeded the recommended TV watching time. Moreover, almost one third of children had a poor linguistic home environment. Three parents whose children were diagnosed with ASD or GDD, refused to be reported as 'autism spectrum disorder' or 'intellectual disability' with the anxiety of labeling their child. As a result, these children were unable to receive special education paid for by the government. This study presented 31 of 100 children needed further diagnostic work up and early intervention. Therefore, pediatricians should not underestimate speech delay. On the other hand, due to the fact that, the regulations to receive special education and therapy often create anxiety for the parents, we think that this system needs to be updated and special education support should be determined by the special needs of each child.WoSScopu
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