PENGARUH KECERDASAN EMOSIONAL TERHADAP KEDISIPLINAN BELAJAR PESERTA DIDIK DI SEKOLAH DASAR

The problem raised in this study is how the level of Emotional Intelligence of SDI Onekore 06 students, how is the level of learning discipline of SDI Onekore 06 students and whether there is an effect of emotional intelligence on student learning discipline at SDI Onekore 06. The purpose of this study is to determine the effect Emotional intelligence on the learning disciplines of SDI Onekore 06 students. This study used correlational quantitative research, which was conducted at SDI Onekore 06, Ende Tengah District, Ende Regency. The sample of this research was students in grades V and VI, who were taken using purposive sampling technique. Data were collected through a questionnaire. Hypothesis testing uses Simple Linear Regression analysis with the Pearson Product Moment Correlation formula. The results of this study indicate that the level of emotional intelligence tends to be high with an average of 94.5 and the level of discipline tends to be high with an average of 93.50. There is a significant influence between emotional intelligence on learning discipline. This can be seen from the results of statistical analysis which shows the correlation coefficient (r) of 0.419 which states that the correlation index (r) X to Y is sufficient with an effect of 17.6% and Sig = 0.014 at the significance level alpha ( = 0.05

STUDENT'S PERCEPTION TOWARDS THE USE OF EDMODO IN LEARNING EFFECTIVE LISTENING IN THE PANDEMIC COVID-19 PERIOD

Virtual class or commonly referred to as online class is one form of learning media that uses the Internet specifically during the quarantine of covid-19. Quantitative descriptive analysis in this study examines the student’s perception of English Literature Study Program Universitas Flores about the use of the Edmodo platform in Effective Listening class at the time of Covid-19 quarantine. The number of samples in this study is 44 students of English Literature Study Program of Universitas Flores who have been taken Effective Listening class during the Covid-19 quarantine period. The result is that Edmodo platform used in Effective Listening class was positive. The average of 98% of English Literature Study Program Students of Flores University   agreed to use Edmodo applications as learning media to learn Effective Listening Class at Covid-19 quarantine time since it is user-friendly. This is because Edmodo's interface looks like a Facebook as social media that students have known in their daily live

PENDAMPINGAN PELAKSANAAN PENELITIAN TINDAKAN KELAS DAN PENULISAN PUBLIKASI ILMIAH BAGI GURU DI SMA

Pengabdian kepada masyarakat ini memiliki tujuan untuk mengarahkan guru dan memberikan pendampingan saat guru melaksanakan Penelitian Tindakan Kelas (PTK) dan merampungkannya dalam artikel ilmiah yang terpublikasi. Metode pengabdian ini menggunakan pelatihan dengan tahapan yakni pendampingan dalam pembuatan proposal, membantu merancang kegiatan serta perangkat pembelajaran, pendampingan pelaksanaan PTK, hingga mempublikasikannya sebagai publikasi ilmiah pada jurnal nasional Ber ISSN. Hasil kegiatan pengabdian pendampingan ini menunjukkan bahwa bertambahnya wawasan dan motivasi para guru dalam pelaksanaan penelitian tindakan kelas serta lebih memahami tahapan-tahapan dalam proses pelaksanaan PTK. Guru juga mampu menghasilkan Karya ilmiah hasil PTK serta publikasi pada jurnal nasional ber ISSN yang dapat digunakan sebagai syarat kenaikan jabatan fungsional. Kegiatan pengabdian pendampingan pelaksanaan PTK dan penulisan publikasi ilmiah mampu menjadi motivasi untuk meningkatkan kemampuan dan kompetensi guru

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016) : part two

Background The immunological escape of tumors represents one of the main ob- stacles to the treatment of malignancies. The blockade of PD-1 or CTLA-4 receptors represented a milestone in the history of immunotherapy. However, immune checkpoint inhibitors seem to be effective in specific cohorts of patients. It has been proposed that their efficacy relies on the presence of an immunological response. Thus, we hypothesized that disruption of the PD-L1/PD-1 axis would synergize with our oncolytic vaccine platform PeptiCRAd. Methods We used murine B16OVA in vivo tumor models and flow cytometry analysis to investigate the immunological background. Results First, we found that high-burden B16OVA tumors were refractory to combination immunotherapy. However, with a more aggressive schedule, tumors with a lower burden were more susceptible to the combination of PeptiCRAd and PD-L1 blockade. The therapy signifi- cantly increased the median survival of mice (Fig. 7). Interestingly, the reduced growth of contralaterally injected B16F10 cells sug- gested the presence of a long lasting immunological memory also against non-targeted antigens. Concerning the functional state of tumor infiltrating lymphocytes (TILs), we found that all the immune therapies would enhance the percentage of activated (PD-1pos TIM- 3neg) T lymphocytes and reduce the amount of exhausted (PD-1pos TIM-3pos) cells compared to placebo. As expected, we found that PeptiCRAd monotherapy could increase the number of antigen spe- cific CD8+ T cells compared to other treatments. However, only the combination with PD-L1 blockade could significantly increase the ra- tio between activated and exhausted pentamer positive cells (p= 0.0058), suggesting that by disrupting the PD-1/PD-L1 axis we could decrease the amount of dysfunctional antigen specific T cells. We ob- served that the anatomical location deeply influenced the state of CD4+ and CD8+ T lymphocytes. In fact, TIM-3 expression was in- creased by 2 fold on TILs compared to splenic and lymphoid T cells. In the CD8+ compartment, the expression of PD-1 on the surface seemed to be restricted to the tumor micro-environment, while CD4 + T cells had a high expression of PD-1 also in lymphoid organs. Interestingly, we found that the levels of PD-1 were significantly higher on CD8+ T cells than on CD4+ T cells into the tumor micro- environment (p < 0.0001). Conclusions In conclusion, we demonstrated that the efficacy of immune check- point inhibitors might be strongly enhanced by their combination with cancer vaccines. PeptiCRAd was able to increase the number of antigen-specific T cells and PD-L1 blockade prevented their exhaus- tion, resulting in long-lasting immunological memory and increased median survival

Pembelajaran Basic English Vocabularies untuk Siswa Tingkat Sekolah Dasar, di Desa Libunio, Kecamatan So’a, Kabupaten Ngada

English is one of the languages that have to be mastered from an early stage. Language skills that have to be mastered consist of listening, speaking, reading and writing. Vocabulary has an important role in supporting the development of language skills. Vocabulary introduced to elementary students were basic vocabularies that were easy to memorize, remember and implement in communicating. Vocabularies were presented well-equipped with pictures and students felt it easy to remember. The approach was a deductive approach equipped with game and reward. Games and rewards are very helpful in facilitating students’ active engagement during the learning process. The learning environment feels alive, not boring, and students feel happy and more relaxe

PROBLEMATIKA PEMBELAJARAN DARING SISWA KELAS VII SMPN 1 ENDE SELATAN, KABUPATEN ENDE

The pandemic of covid 19 had big effects in educational field. The transition of learning process from face to face into online had many obstacles. Teachers, students and parents had their own problems to face it. Parents had to provide facilities to their child during online learning process but their economic factors were inadequate, such as buying android phone or data package. There were parents and teachers were not able to use the technology effectively and efficiently.&nbsp; It can be effect to the students. Students will left behind the materials and the assignments had given by their teachers. Door to door was an approach offered to avoid or to minimize that problems.&nbsp; The aim of that approach was teachers could share the materials, the assignment and guiding their students directly. Learning guidance could be the materials which were not understood and teaching them how to use android phone to access the materials shared through online learning. In order that, door to door approach which had implemented besides helped students to understand more the materials but also the students got learning guidance effectively about the way to utilize the learning technology. It was about the materials were shared online. In this case, teacher should actively guiding their students to use the technology in better way. Furthermore, the teacher will adding new knowledge, so they do not seems out of touch of information and blinded technology

PENDAMPINGAN KEGIATAN FUN WITH ENGLISH PADPENDAMPINGAN KEGIATAN FUN WITH ENGLISH PADA SERIKAT ANAK MISIONER (SEKAMI) STASI ST. ZAKHARIA, KEUSUKUPAN AGUNG ENDE, FLORES, NTT

ABSTRAKBahasa Inggris merupakan bahasa pengantar yang digunakan untuk berkomunikasi diseluruh dunia. Pembelajaran bahasa Inggris untuk pemula (beginners) adalah hal yang harus dilakukan sehingga bisa dijadikan bekal untuk anak dimasa depan. Tujuan dari kegiatan pendampingan ini adalah untuk memperkenalkan bahasa Inggris sejak dini kepada anak-anak serta mampu meningkatkan motivasi serta rasa percaya diri anak-anak dalam menggunakan bahasa Inggris. Salah satu aktivitas yang dilakukan adalah kegiatan Fun with English yang merupakan a recommended activity to motivate kids in learning English dengan menerapkan metode pembelajaran yang beragam sehingga anak-anak tidak merasa jenuh bahkan bosan dalam proses belajar seperti ceramah, Think Pair Share, games serta lagu-lagu berbahasa Inggris. Dari kegiatan ini anak-anak SEKAMI menjadi merasa percaya diri, pembelajaran yang diberikanpun sangat disenangi oleh anak-anak. Saran bagi pemerhati bahasa Inggris adalah untuk lebih meningkatkan kreativitas melalui berbagai macam cara untuk membumikan bahasa Inggris di bumi nusantara. Kata kunci: fun with English; SEKAMI. ABSTRACTEnglish language is a medium language which used to communicate in all over the world. English learning for the beginners is the important thing that have to do so that it can be supplied for their future. The aim of this activity was to introduce English as early as possible to children and could enhance their motivation and their confidence in using English. One of the activity is Fun with English activity that is a recommended activity to motivate children in learning English by implementing various learning methods in order that the children will never get bored and saturated during learning process. These activities such as lectures, Think Pair Share, games and also English songs. From this activity, the children of SEKAMI become have their self confidence, they felt happy with the materials are given by their teacher. The suggestion is addressed to English observer is they have to be more aware in increasing the creativity through many activities. Keywords: fun with English, SEKAM

Analysis of Outcomes in Ischemic vs Nonischemic Cardiomyopathy in Patients With Atrial Fibrillation A Report From the GARFIELD-AF Registry

IMPORTANCE Congestive heart failure (CHF) is commonly associated with nonvalvular atrial fibrillation (AF), and their combination may affect treatment strategies and outcomes