35 research outputs found
Impact of Different Fertilizer Sources under Supplemental Irrigation and Rainfed Conditions on Eco-Physiological Responses and Yield Characteristics of Dragonâs Head (Lallemantia iberica)
The effects of the irrigation regime and different fertilizer sources on the eco-physiological responses and yield characteristics of dragonâs head were explored in a factorial experiment based on a randomized complete block design with 12 treatments and 3 replications in the 2019 growing season. The treatments included six different fertilizer sources (animal manure, vermicompost, poultry manure, biofertilizer, chemical fertilizer, and control) and two irrigation regimes (rainfed and supplemental irrigation). The results indicated the positive effects of supplementary irrigation and the application of vermicompost, poultry manure, and animal manure by increasing the absorption of nutrients (phosphorus and potassium) and improving relative water contents, chlorophyll and carotenoid contents, and the fixed oil percentage of dragonâs head. The activities of catalase, ascorbate peroxidase, and superoxide dismutase decreased in the rainfed plants, whereas organic fertilizer application increased the antioxidant enzyme activity. The highest grain yield (721 kg haâ1), biological yield (5858 kg haâ1), total flavonoids (1.47 mg gâ1 DW), total phenol (27.90 mg gâ1 DW), fixed oil yield (200.17 kg haâ1), and essential oil yield (1.18 kg haâ1) were noted in plants that were treated with vermicompost under supplemental irrigation. Therefore, it is recommended that organic fertilizers such as vermicompost and poultry manure be used to substitute chemical fertilizers. These practices can help popularize organic crops using rainfed and supplementary irrigation
Synthesis, Structure, and Biological Assays of Novel TrifluoromethyldiazepineâMetal Complexes
A new series of CuII, NiII, CoII, and MnIII complexes have been synthesised from the (6Z)-6-(7-trifluoromethyl-1,2,3,4-tetrahydro-5H-1,4-diazepin-5-ylidene)cyclohexa-2,4-dien-1-one (HDZP) ligand. These complexes were characterised by elemental, spectroscopic (IR and UV-vis), and thermal analysis. The crystal structure of Cu-DZP was solved by X-ray diffraction methods. The complex crystallises in the monoclinic P21/c space group, with two molecules per unit cell. The crystal lattice is stabilised by different intra and intermolecular interactions. Hirshfeld surface analysis was employed to obtain additional information about interactions that are responsible for the crystal packing. Quantitative examination of the fingerprint plots indicated the dominant contribution of HâŻH and HâŻX (X = O, F) interactions in the crystal packing. In addition, C-HâŻchelate ring (CR) and C-HâŻÏ interactions are described in detail and evaluated using DFT calculations. The antibacterial properties and the mechanism of inhibition of the main bacterial resistant mechanism, the biofilm, of the metal complexes and free ligand were investigated. [Mn(DZP)3]·2H2O was the most active complex against the Pseudomonas aeruginosa biofilm formation with an inhibition of 40 %. However, none of the complexes inhibit more than 25 % of the Gram negative bacteria microbial development. The most meaningful result was the bactericidal effect of [Co(DZP)2(H2O)2]·2H2O against the Gram positive bacteria, Staphylococcus aureus, which inhibits the bacterial development and significantly reduces the biofilm formation at low concentration.Fil: Rocha, Mariana. Universidad Nacional de TucumĂĄn; Argentina. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico Conicet - TucumĂĄn. Instituto de QuĂmica del Noroeste. Universidad Nacional de TucumĂĄn. Facultad de BioquĂmica, QuĂmica y Farmacia. Instituto de QuĂmica del Noroeste; ArgentinaFil: EcheverrĂa, Gustavo Alberto. Facultad de Ciencias Exactas, Universidad Nacional de la Plata; Argentina. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico Conicet - La Plata. Instituto de FĂsica La Plata. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de FĂsica La Plata; ArgentinaFil: Piro, Oscar Enrique. Facultad de Ciencias Exactas, Universidad Nacional de la Plata; Argentina. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico Conicet - La Plata. Instituto de FĂsica La Plata. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de FĂsica La Plata; ArgentinaFil: Jios, Jorge Luis. Facultad de Ciencias Exactas, Universidad Nacional de la Plata; ArgentinaFil: Molina, RocĂo Daniela InĂ©s. Universidad Nacional de TucumĂĄn; Argentina. Universidad Nacional de TucumĂĄn. Instituto de BiotecnologĂa FarmacĂ©utica y Alimentaria. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico Conicet - TucumĂĄn. Instituto de BiotecnologĂa FarmacĂ©utica y Alimentaria; ArgentinaFil: Arena, Mario Eduardo. Universidad Nacional de TucumĂĄn; Argentina. Universidad Nacional de TucumĂĄn. Instituto de BiotecnologĂa FarmacĂ©utica y Alimentaria. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico Conicet - TucumĂĄn. Instituto de BiotecnologĂa FarmacĂ©utica y Alimentaria; ArgentinaFil: Ulic, Sonia Elizabeth. Facultad de Ciencias Exactas, Universidad Nacional de la Plata; Argentina. Universidad Nacional de LujĂĄn; Argentina. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico Conicet - La Plata. Centro de QuĂmica InorgĂĄnica "Dr. Pedro J. Aymonino". Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de QuĂmica InorgĂĄnica "Dr. Pedro J. Aymonino"; ArgentinaFil: Gil, Diego Mauricio. Universidad Nacional de TucumĂĄn; Argentina. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico Conicet - TucumĂĄn. Instituto de QuĂmica del Noroeste. Universidad Nacional de TucumĂĄn. Facultad de BioquĂmica, QuĂmica y Farmacia. Instituto de QuĂmica del Noroeste; Argentin
Synthesis, characterization and crystal structure of 2-chloroethyl(methylsulfonyl)methanesulfonate
The aim of this study was to evaluate the structural and vibrational properties and biological activity of 2-chloroethyl(methylsulfonyl)methanesulfonate, CH3SO2CH2SO2OCH2CH2Cl (clomesone). The solid-state molecular structure has been isolated and characterized using experimental (X-ray diffraction) and theoretical (DFT method) methodologies. The molecules are packed through C-HâŻO bifurcated interactions and ClâŻCl interactions. The experimental investigations are supplemented by quantum chemical calculations and Hirshfeld surface calculations. Furthermore, the infrared and Raman spectra of the solid phase have been obtained, and the observed bands are assigned to the vibrational normal modes. This study is completed using the atoms-in-molecules (AIM) theory and natural bond orbital (NBO) analysis. Finally, we studied the function of clomesone in biofilm formation and investigated a methanesulfonate complex with respect to QS activity.Fil: GalvĂĄn, Jorge Edgardo. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico Conicet - TucumĂĄn. Instituto de QuĂmica del Noroeste. Universidad Nacional de TucumĂĄn. Facultad de BioquĂmica, QuĂmica y Farmacia. Instituto de QuĂmica del Noroeste; ArgentinaFil: Defonsi Lestard, Maria Eliana. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico Conicet - TucumĂĄn. Instituto de QuĂmica del Noroeste. Universidad Nacional de TucumĂĄn. Facultad de BioquĂmica, QuĂmica y Farmacia. Instituto de QuĂmica del Noroeste; ArgentinaFil: Piro, Oscar Enrique. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico Conicet - La Plata. Instituto de FĂsica La Plata. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de FĂsica La Plata; ArgentinaFil: EcheverrĂa, Gustavo Alberto. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico Conicet - La Plata. Instituto de FĂsica La Plata. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de FĂsica La Plata; ArgentinaFil: Molina, RocĂo Daniela InĂ©s. Universidad Nacional de TucumĂĄn. Instituto de BiotecnologĂa FarmacĂ©utica y Alimentaria. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico Conicet - TucumĂĄn. Instituto de BiotecnologĂa FarmacĂ©utica y Alimentaria; ArgentinaFil: Arena, Mario Eduardo. Universidad Nacional de TucumĂĄn. Instituto de BiotecnologĂa FarmacĂ©utica y Alimentaria. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico Conicet - TucumĂĄn. Instituto de BiotecnologĂa FarmacĂ©utica y Alimentaria; ArgentinaFil: Ulic, Sonia Elizabeth. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico Conicet - La Plata. Centro de QuĂmica InorgĂĄnica "Dr. Pedro J. Aymonino". Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Centro de QuĂmica InorgĂĄnica "Dr. Pedro J. Aymonino"; Argentina. Universidad Nacional de LujĂĄn. Departamento de Ciencias BĂĄsicas; ArgentinaFil: Tuttolomondo, MarĂa Eugenia. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico Conicet - TucumĂĄn. Instituto de QuĂmica del Noroeste. Universidad Nacional de TucumĂĄn. Facultad de BioquĂmica, QuĂmica y Farmacia. Instituto de QuĂmica del Noroeste; ArgentinaFil: Ben Altabef, AĂda. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico Conicet - TucumĂĄn. Instituto de QuĂmica del Noroeste. Universidad Nacional de TucumĂĄn. Facultad de BioquĂmica, QuĂmica y Farmacia. Instituto de QuĂmica del Noroeste; Argentin
Synthesis, characterization and crystal structure of 2-chloroethyl(methylsulfonyl)methanesulfonate
The aim of this study was to evaluate the structural and vibrational properties and biological activity of 2-chloroethyl(methylsulfonyl)methanesulfonate, CH3SO2CH2SO2OCH2CH2Cl (clomesone). The solid-state molecular structure has been isolated and characterized using experimental (X-ray diffraction) and theoretical (DFT method) methodologies. The molecules are packed through C-HâŻO bifurcated interactions and ClâŻCl interactions. The experimental investigations are supplemented by quantum chemical calculations and Hirshfeld surface calculations. Furthermore, the infrared and Raman spectra of the solid phase have been obtained, and the observed bands are assigned to the vibrational normal modes. This study is completed using the atoms-in-molecules (AIM) theory and natural bond orbital (NBO) analysis. Finally, we studied the function of clomesone in biofilm formation and investigated a methanesulfonate complex with respect to QS activity.Centro de QuĂmica InorgĂĄnicaInstituto de FĂsica La Plat
Anålisis técnico-económico sobre la decisión de reforzamiento o construcción nueva de la estructura de un centro educativo
La siguiente investigaciĂłn se realiza por la necesidad de conocer alternativas que cambien la situaciĂłn de distintos centros educativos que en los Ășltimos años se han visto muy afectados a causa de los sismos ocurridos en nuestro paĂs. Es de suma importancia conocer si los distintos centros educativos resistirĂĄn a sismos de grandes magnitudes y si necesitan un reforzamiento estructural para que presenten un buen desempeño o serĂĄ necesario su demoliciĂłn y una posterior reconstrucciĂłn de acuerdo a las nuevas normas de diseño sismorresistente. El objetivo general del presente proyecto de investigaciĂłn consiste en definir la opciĂłn Ăłptima en tĂ©rminos tĂ©cnico-econĂłmicos entre las dos alternativas planteadas; la demoliciĂłn y posterior reconstrucciĂłn de la estructura, o el reforzamiento de la estructura. Se usan como base en el siguiente proyecto distintas investigaciones de reforzamiento sĂsmico de los centros educativos en el PerĂș, investigaciones que persisten en evaluar la vulnerabilidad sĂsmica. En el presente trabajo se analizan de manera tĂ©cnica y econĂłmica dos alternativas de reforzamiento en sentido longitudinal que serĂĄn la colocaciĂłn de aletas de concreto armado y el cierre de paños con albañilerĂa, mĂ©todos que serĂĄn aplicados en un pabellĂłn tĂpico considerando parĂĄmetros mĂĄs desfavorables para posteriormente determinar la mejor opciĂłn respecto al costo de reparaciĂłn o de construcciĂłn de un nuevo centro educativo. Finalmente, en esta investigaciĂłn se concluye que es necesario tener no solo un anĂĄlisis tĂ©cnico sino tambiĂ©n econĂłmico ya que en los proyectos de gran envergadura, en el paĂs, cada nuevo sol (S/.) es vital para la elecciĂłn de la mejor alternativa de mejoramiento o saneamiento de infraestructuras y se recomienda que las futuras edificaciones de centros educativos sean construidas bajo el sistema de pĂłrticos duales, ademĂĄs de aislar la tabiquerĂa de las columnas a fin de evitar la falla de columna corta que es tan recurrente.Trabajo de investigaciĂł
Synthesis, structure, and biological assays of novel trifluoromethyldiazepineâmetal complexes
A new series of CuII, NiII, CoII, and MnIII complexes have been synthesised from the (6Z)-6-(7-trifluoromethyl-1,2,3,4-tetrahydro-5H-1,4-diazepin-5-ylidene)cyclohexa-2,4-dien-1-one (HDZP) ligand. These complexes were characterised by elemental, spectroscopic (IR and UV-vis), and thermal analysis. The crystal structure of Cu-DZP was solved by X-ray diffraction methods. The complex crystallises in the monoclinic P21/c space group, with two molecules per unit cell. The crystal lattice is stabilised by different intra and intermolecular interactions. Hirshfeld surface analysis was employed to obtain additional information about interactions that are responsible for the crystal packing. Quantitative examination of the fingerprint plots indicated the dominant contribution of HâŻH and HâŻX (Xâ=âO, F) interactions in the crystal packing. In addition, CâHâŻchelate ring (CR) and CâHâŻÏ interactions are described in detail and evaluated using DFT calculations. The antibacterial properties and the mechanism of inhibition of the main bacterial resistant mechanism, the biofilm, of the metal complexes and free ligand were investigated. [Mn(DZP)â]·2HâO was the most active complex against the Pseudomonas aeruginosa biofilm formation with an inhibition of 40â%. However, none of the complexes inhibit more than 25â% of the Gram negative bacteria microbial development. The most meaningful result was the bactericidal effect of [Co(DZP)â(HâO)â]·2HâO against the Gram positive bacteria, Staphylococcus aureus, which inhibits the bacterial development and significantly reduces the biofilm formation at low concentration.Instituto de FĂsica La PlataPlanta Piloto MultipropĂłsito - Laboratorio de Servicios a la Industria y al Sistema CientĂficoCentro de QuĂmica InorgĂĄnic
Factors Associated with Emotion Regulation in Men with Internet Access Living in Brazil during the COVID-19 Pandemic
Publisher Copyright: © 2022 by the authors. Licensee MDPI, Basel, Switzerland.Objective: to evaluate the factors associated with emotion regulation in men with internet access living in Brazil during the COVID-19 pandemic. Method: an epidemiological survey, conducted with 1015 men. An electronic form was applied containing sociodemographic and occu-pational characteristics, support and coping strategies, as well as emotional and behavioral aspects. Emotion regulation was assessed using the Emotion Regulation Questionnaire. Results: The prevalence values observed were 44.6% for Low Cognitive Reappraisal and of 47.1% for High Emotional Sup-pression. The following factors were identified as associated: (a) with Low Cognitive Reappraisal: being aged 30 years old or more, practicing physical activity, worrying about social distancing and having positive emotions and feelings; and (b) with High Emotional Suppression: being heterosexual, non-white race/skin color, having security support or public administration, not sanitizing food, worrying about lack of physical activity and not having negative emotions. Conclusion: the adoption of emotion regulation strategies was associated with individual, contextual and emotional/behavioral characteristics. Masculinity ideals seem to exert an influence on these relationships.publishersversionpublishe
Prospective validation of the CLIP score: a new prognostic system for patient with cirrhosis and hepatocellular carcinoma
Prognosis of patients with cirrhosis and hepatocellular carcinoma (HCC) depends on both residual liver function and tumor extension. The CLIP score includes Child-Pugh stage, tumor morphology and extension, serum alfa-fetoprotein (AFP) levels, and portal vein thrombosis. We externally validated the CLIP score and compared its discriminatory ability and predictive power with that of the Okuda staging system in 196 patients with cirrhosis and HCC prospectively enrolled in a randomized trial. No significant associations were found between the CLIP score and the age, sex, and pattern of viral infection. There was a strong correlation between the CLIP score and the Okuda stage, As of June 1999, 150 patients (76.5%) had died. Median survival time was 11 months, overall, and it was 36, 22, 9, 7, and 3 months for CLIP categories 0, 1, 2, 3, and 4 to 6, respectively. In multivariate analysis, the CLIP score had additional explanatory power above that of the Okuda stage. This was true for both patients treated with locoregional therapy or not. A quantitative estimation of 2-year survival predictive power showed that the CLIP score explained 37% of survival variability, compared with 21% explained by Okuda stage. In conclusion, the CLIP score, compared with the Okuda staging system, gives more accurate prognostic information, is statistically more efficient, and has a greater survival predictive power. It could be useful in treatment planning by improving baseline prognostic evaluation of patients with RCC, and could be used in prospective therapeutic trials as a stratification variable, reducing the variability of results owing to patient selection
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Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study
Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347Funder: Flemish Society for Critical Care NursesAbstract: Purpose: Intensive care unit (ICU) patients are particularly susceptible to developing pressure injuries. Epidemiologic data is however unavailable. We aimed to provide an international picture of the extent of pressure injuries and factors associated with ICU-acquired pressure injuries in adult ICU patients. Methods: International 1-day point-prevalence study; follow-up for outcome assessment until hospital discharge (maximum 12 weeks). Factors associated with ICU-acquired pressure injury and hospital mortality were assessed by generalised linear mixed-effects regression analysis. Results: Data from 13,254 patients in 1117 ICUs (90 countries) revealed 6747 pressure injuries; 3997 (59.2%) were ICU-acquired. Overall prevalence was 26.6% (95% confidence interval [CI] 25.9â27.3). ICU-acquired prevalence was 16.2% (95% CI 15.6â16.8). Sacrum (37%) and heels (19.5%) were most affected. Factors independently associated with ICU-acquired pressure injuries were older age, male sex, being underweight, emergency surgery, higher Simplified Acute Physiology Score II, Braden score 3 days, comorbidities (chronic obstructive pulmonary disease, immunodeficiency), organ support (renal replacement, mechanical ventilation on ICU admission), and being in a low or lower-middle income-economy. Gradually increasing associations with mortality were identified for increasing severity of pressure injury: stage I (odds ratio [OR] 1.5; 95% CI 1.2â1.8), stage II (OR 1.6; 95% CI 1.4â1.9), and stage III or worse (OR 2.8; 95% CI 2.3â3.3). Conclusion: Pressure injuries are common in adult ICU patients. ICU-acquired pressure injuries are associated with mainly intrinsic factors and mortality. Optimal care standards, increased awareness, appropriate resource allocation, and further research into optimal prevention are pivotal to tackle this important patient safety threat