Effect of social support on migrant workers' mental health: a systematic review

[ES] Introducción: Los trabajadores inmigrantes son una población especialmente vulnerable a desarrollar trastornos de la esfera psicosocial, en probable relación con las diferencias que este grupo de trabajadores presenta: barrera idiomática, dificultad para acceder al sistema, desconocimiento de recursos disponibles, falta y/o ausencia de una red de apoyo social estable y segura. Objetivo: Conocer la incidencia de trastornos psicosociales en trabajadores inmigrantes y la influencia del apoyo sociosanitario en el desarrollo o aparición de los mismos. Material y Métodos: Revisión de Revisiones Sistemáticas con búsqueda en Medline (Pubmed), Embase, Cochrane, Google Académico y Journal of Inmigrant and Minority Health. Se incluyeron revisiones sistemáticas publicadas entre 2003 y diciembre de 2021, en inglés y español. Se empleó AMSTAR2 para evaluar la calidad de los estudios incluidos. Resultados: Se incluyeron tres revisiones sistemáticas, de calidad intermedia. Los estudios mostraban que los trabajadores inmigrantes, presenta más riesgo de desarrollar depresión y hay una prevalencia mayor de ésta, debido a diversos factores como falta de apoyo social y familiar, la incertidumbre o el tipo de trabajo que desarrollan. En cuanto a ansiedad, también se vio un aumento del riesgo y la prevalencia en trabajadores inmigrantes, debido a los mismos factores. Conclusión: Es necesario desarrollar estrategias de prevención para la protección de la salud mental de los trabajadores inmigrantes, ya que por sus característica presentan un mayor riesgo psicosocial con aumento de prevalencia de enfermedades como depresión y ansiedad. Es importante conocer las características de los trabajadores, con el fin de poder emplear los recursos preventivos más acertados. [EN] Introduction: Migrant workers are a special kind of group with notable vulnerability to develop more psychosocial disorders compared to native workers, which may be due to several disadvantages such as language, culture shock, lack of social support or lack of access to health care between others. There are few studies on the health of immigrant groups at present, therefore, it is necessary and vital to explore and identify mental health situation and social support related factors or conditions. Objectives: To have knowledge of the incidence of psychosocial disorders in migrant workers and perceive the influence of social and health support in their development or appearance. Material and Methods: This is a review of Systematic Reviews by searching in Medline (Pubmed), Embase, Cochrane, Google Scholar and Journal of Immigrant and Minority Health. Systematic reviews published between 2003 and December 2022 were included, both in English and Spanish. Results: Three systematic reviews, of intermediate quality according to the AMSTAR2 tool, were included. Regarding depression, they concluded that migrant workers, has a higher risk of developing depression due to some factors such as lack of social and family support, uncertainty, the type of work they develop, etc. Regarding anxiety, an increased risk and prevalence was also seen in migrant workers, also due to the same factors. Conclusion: Prevention strategies are required to protect migrant workers' mental health, as they are a remarkably vulnerable group with a higher psychosocial risk and an increased prevalence of diseases such as depression and anxiety.S

Effectiveness of Modified Vaccinia Ankara-Bavaria Nordic Vaccination in a Population at High Risk of Mpox: A Spanish Cohort Study

Background: With over 7,500 cases notified since April 2022, Spain has experienced the highest incidence of mpox in Europe. From July 12th onwards, the Modified Vaccinia Ankara-Bavaria Nordic (MVA-BN) smallpox vaccine was offered as pre-exposure prophylaxis for individuals at high-risk of mpox, including those receiving pre-exposure prophylaxis for HIV (HIV-PrEP). Our aim was to assess the effectiveness of one dose of MVA-BN vaccine as pre-exposure against mpox virus (MPXV) infection in persons on HIV-PrEP. Methods: We conducted a national retrospective cohort study between July 12 and December 12, 2022. Individuals ≥18 years, receiving HIV-PrEP as of July 12 and with no previous MPXV infection or vaccination were eligible. Each day, we matched individuals receiving a first dose of MVA-BN vaccine and unvaccinated controls of the same age group and region. We used a Kaplan-Meier estimator and calculate risk ratios (RR) and vaccine effectiveness (VE = 1-RR). Results: We included 5,660 matched pairs, with a median follow-up of 62 days (interquartile range 24-97). Mpox cumulative incidence was 5.6 per 1,000 (25 cases) in unvaccinated and 3.5 per 1,000 (18 cases) in vaccinated. No effect was found during days 0-6 post-vaccination (VE -38.3; 95% confidence interval (95%CI): -332.7; 46.4), but VE was 65% in ≥7 days (95%CI 22.9; 88.0) and 79% in ≥14 days (95%CI 33.3; 100.0) post-vaccination. Conclusions: One dose of MVA-BN vaccine offered protection against mpox in a most-at-risk population shortly after the vaccination. Further studies need to assess the VE of a second dose and the duration of protection over time.S

Nuevas Imágenes. Resúmenes y abstracts de comunicaciones. VI Congreso Internacional CONFOCO.

Se presentan los resúmenes de las comunicaciones del VI Congreso Internacional CONFOCO

Treatment with tocilizumab or corticosteroids for COVID-19 patients with hyperinflammatory state: a multicentre cohort study (SAM-COVID-19)

Objectives: The objective of this study was to estimate the association between tocilizumab or corticosteroids and the risk of intubation or death in patients with coronavirus disease 19 (COVID-19) with a hyperinflammatory state according to clinical and laboratory parameters. Methods: A cohort study was performed in 60 Spanish hospitals including 778 patients with COVID-19 and clinical and laboratory data indicative of a hyperinflammatory state. Treatment was mainly with tocilizumab, an intermediate-high dose of corticosteroids (IHDC), a pulse dose of corticosteroids (PDC), combination therapy, or no treatment. Primary outcome was intubation or death; follow-up was 21 days. Propensity score-adjusted estimations using Cox regression (logistic regression if needed) were calculated. Propensity scores were used as confounders, matching variables and for the inverse probability of treatment weights (IPTWs). Results: In all, 88, 117, 78 and 151 patients treated with tocilizumab, IHDC, PDC, and combination therapy, respectively, were compared with 344 untreated patients. The primary endpoint occurred in 10 (11.4%), 27 (23.1%), 12 (15.4%), 40 (25.6%) and 69 (21.1%), respectively. The IPTW-based hazard ratios (odds ratio for combination therapy) for the primary endpoint were 0.32 (95%CI 0.22-0.47; p < 0.001) for tocilizumab, 0.82 (0.71-1.30; p 0.82) for IHDC, 0.61 (0.43-0.86; p 0.006) for PDC, and 1.17 (0.86-1.58; p 0.30) for combination therapy. Other applications of the propensity score provided similar results, but were not significant for PDC. Tocilizumab was also associated with lower hazard of death alone in IPTW analysis (0.07; 0.02-0.17; p < 0.001). Conclusions: Tocilizumab might be useful in COVID-19 patients with a hyperinflammatory state and should be prioritized for randomized trials in this situatio

Biometric testicular and serum testosterone concentration of Brazilian Ponies stallions Biometria testicular e concentrações séricas de testosterona de garanhões Pôneis da raça Brasileira

SUMMARY Evaluation of the testis size is very important in stallions&apos; selection, since it is an indirect determinant of their reproductive potential. The aim of this study was to evaluate the biometric testicular traits, calculate the volume testicular and analyze the serum testosterone concentration of the stallion. During six months were measured the tests of adults Brazilian Ponies stallions from northern of Rio de Janeiro State, Brazil. The length, the width and the height of the testicles (TL, TW and TH) were measured. From these measurements, the total testicular volume (TTV) was calculated. The serum testosterone concentration was also evaluated. The data were studied by analysis of variance and were calculated the correlations among the traits. The average of the testis biometry were TL 5.8 ± 0.6 cm; TW 3.8 ± 0.5 cm; TH 4.7 ± 0.4 cm and 111.2 ± 27.7 for TTV. Mean of serum testosterone concentration was 0.89 ± 0.52 ng/dl. High correlations between biometry testicular traits with testicular volume were observed and low to moderate correlations were observed for testicular traits, testosterone and sperm output. The testis size could be an important trait that assists to the prediction of stallion&apos;s reproductive potential of the Brazilian ponies stallions. It is suggested that there would be no fluctuation in serum testosterone concentration in Brazilian ponies stallions that coult afect on its fertility. Keywords: andrology, horse, reproduction RESUMO Avaliação do tamanho dos testículos é muito importante na seleção de garanhões, uma vez que é um determinante indireto do seu potencial reprodutivo. O objetivo deste estudo foi avaliar as características de biometria testiculares, calcular o volume testicular e analisar a concentração sérica de testosterona de garanhões. Durante seis meses, foram medidos os testículos de garanhões Pôneis da raça Brasileiro adultos, criados no Norte do Estado do Rio de Janeiro, Brasil. O comprimento a largura e a altura dos testículo (TL, TW e TH) foram mensurados. A partir dessas medidas, calculou-se o volume testicular total (TTV). Os dados foram avaliados por análise de variância e foram calculadas as correlações entre as características. A média geral das características de biometria testicular e volume testicular foram: TL 5,8 ± 0,6 cm; TW 3,8 ± 0,5 cm; TH 4,7 ± 0,4 cm e TTV 111.2 ± 27,7. A média de concentração sérica de testosterona foi de 0,89 ± 0,52 ng/dl. Altas correlações foram observadas entre as características de biometria testicular e volume testicular. Baixas a médias correlações entre as características testiculares com produção espermática e com concentração de testosterona foram observadas. O tamanho testicular pode ser uma importante característica que auxilia na predição do potencial reprodutivo do garanhão pôneis da raça Brasileira. Sugere-se que não há variações na concentração sérica de testosterona nos pôneis da raça Brasileira que poderia afetar em sua fertilidade. Palavras-chave: andrologia, equino, reprodução Rev

The testing season affects red deer skinfold increase in response to phytohaemagglutinin

Red deer (Cervus elaphus) have a pronounced seasonality in their physiology. The aim of this study was to assess the effect of the season on red deer responsiveness to skin testing with the phytohaemagglutinin (PHA) mitogen. Study subjects included 270 farmed adult red deer (19 stags and 251 hinds). The skin testing was carried out between January 2009 and August 2010. The animals were injected intradermally with a 0.1. ml volume containing 250 μg of PHA diluted in phosphate buffered saline. The skinfold thickness was measured immediately prior to injection and 72. h after administration, always by the same person and with three repeats per measurement. Single effects of sex and time on skin test responsiveness were significant (p< 0.001) as well as their interaction (p< 0.001). In winter (January), and considering the average of two years, the skinfold increase in response to the intradermal injection of 250 μg PHA was 2.1 times larger in stags and 1.4 times in hinds than in summer (August). While stags had 1.3 times larger responses than hinds in winter, the inverse occurred in summer, with 1.1 times larger responses in hinds. We also evidenced a limited inter-annual variation of skinfold increase in response to PHA in red deer. These findings have important consequences regarding the interpretation of skin test results in the ante-mortem diagnosis of tuberculosis and paratuberculosis, at least in deer.This work was supported by projects “Control of Tuberculosis in Wildlife” of Grupo Santander and Fundación Marcelino Botín, EU grant TB-STEP 212414, CICYT–MCINN research grant AGL2008-03875, and FEDER (Spain). I.G. Fernández-de-Mera was funded by MCINN Programa Juan de la Cierva, Spain.Peer Reviewe

Diversity of indigenous sheep of an isolated population

Abstract Background Because of the influence of genetics on animal production and the risk of losing genetic diversity of naturally adapted breeds, this study evaluated the genetic diversity of sheep of the Morada Nova breed belonging to an animal science institute in Brazil. The herd in question is one of the country’s most representative of the breed. Samples of DNA extracted from the plasma of 61 animals were used for later analysis of the genotypes using microsatellite molecular markers. Results The polymorphic information content was 0.66, the observed heterozygosity was 0.65 and the fixation index was 0.048. According to the results, there is moderate genetic diversity in the studied population, suggesting the implantation of breeding programs aimed at conservation of the observed genetic diversity. Conclusion The results obtained in this study will be of great importance to decisions on herd structure, besides contributing to other work to be carried out at the research center

Juegos populares de Burgos y otros paises

Realizado a través del centro de formación e innovación educativa de Burgos con la participación de ocho maestros de educación física de seis centros de la provincia que imparten docencia en Educación Primaria. Los objetivos planteados son: - Recuperar los juegos tradicionales, no sólo de la zona, sino también de los países de los que proceden los alumnos extranjeros que acuden a los centros escolares implicados en el proyecto; - Divulgar los juegos; - Ofrecer materiales y recursos para su introducción en cualquier colegio. El proceso llevado a cabo ha sido : 1- Recopilación de juegos realizada por cada profesor en el contexto aula y en el entorno social, 2- Elaboración del dossier recopilatorio, 3- Elaboración de unidades didáctica, 4- Puesta en práctica de las unidades en el aula, 5- Desarrollo de las actividades de las unidades didácticas con el programa CLIC. Los resultados más destacables son la elaboración de materiales didáctico: unidades didácticas, paquetes de actividades CLIC, base de datos de juegos y materiales elaborados por los alumnos así mismo se ha constatado un aumento de los recursos lúdicos de los niños para su tiempo libre, la mejora de su bagaje cultural, el fomento de su desarrollo motor y un respeto hacia la cultura de los compañeros que proceden de otros paises. Trabajo no publicado.Junta de Castilla y LeónCastilla y LeónConsejería de Educación. Dirección General de Universidades e Investigación; Monasterio de Nuestra Señora de Prado, Autovía Puente Colgante, s. n.; 47071 Valladolid; Tel. +34983411881; Fax +34983411939ES