Clinical characterization of PFAPA Syndrome in a Primary Care Pediatric Unit: presentation of a series of cases.

El Síndrome de PFAPA (Fiebre Periódica, Adenopatías, Faringitis y Aftas) entra dentro del diagnóstico diferencial de la fiebre periódica en pediatría, siendo una de sus causas más frecuentes. Aunque se sabe que se debe a una desregulación del sistema inmune, su etiología no está del todo esclarecida. Dado que los criterios diagnósticos son sencillos pero inespecíficos, debemos tener en mente un amplio grupo de enfermedades autoinflamatorias en nuestro diagnóstico diferencial. Los episodios ceden de forma brusca a la corticoterapia, mientras que para la prevención de los mismos no parece haber todavía un tratamiento del todo efectivo. Proponemos una revisión de este síndrome a raíz de cinco casos acaecidos en nuestro centro de salud.The PFAPA syndrome (Periodic Fever, Adenopathy, Pharingitis, Afthae) is part of the differential diagnosis of periodic fever in children. Although there is a dysregulation of the immune system, its etiology is not completely clear. The diagnostic criteria are simple but non-specific, so we must consider a large group of autoinflammatory diseases in our differential diagnosis. A single dose of glucocorticoids given at the onset of an episode can dramatically abort fever attacks in a few hours. Nevertheless, there isn't an effective treatment for the prevention of the episodes. We propose a review of this syndrome as a result of five cases in our health care center

Paediatricians provide higher quality care to children and adolescents in primary care: A systematic review

Aim: The number of primary care paediatricians is decreasing in Europe without a justifiable reason. We aimed to compare the clinical practice of paediatricians and family doctors attending children and adolescents in primary care. Methods: MEDLINE, Embase, CENTRAL, TRIP and Google Scholar were searched from December 2008 to February 2018. No language or study design restrictions were applied. Three reviewers assessed eligibility of the studies. Seven pairs of reviewers performed the data extraction and assessed the methodological quality independently. Discrepancies were resolved by consensus. Results: Fifty-four, out of 1150 studies preselected, were included. We found that paediatricians show more appropriate pharmacology prescription patterns for the illness being treated; they achieve higher vaccination rates and have better knowledge of vaccines and fewer doubts about vaccine safety; their knowledge and implementation of different screening tests are better; they prescribe psychoactive drugs more cautiously and more in line with current practice guidelines; their evaluation and treatment of obesity and lipid disorders follow criteria more consistently with current clinical practice guidelines; and they perform fewer diagnostic test, show a more suitable use of the test and request fewer referrals to specialists. Conclusion: According to published data, in developed countries, paediatricians provide higher quality care to children than family doctors

Paediatricians provide higher quality care to children and adolescents in primary care: A systematic review

Aim: The number of primary care paediatricians is decreasing in Europe without a justifiable reason. We aimed to compare the clinical practice of paediatricians and family doctors attending children and adolescents in primary care. Methods: MEDLINE, Embase, CENTRAL, TRIP and Google Scholar were searched from December 2008 to February 2018. No language or study design restrictions were applied. Three reviewers assessed eligibility of the studies. Seven pairs of reviewers performed the data extraction and assessed the methodological quality independently. Discrepancies were resolved by consensus. Results: Fifty-four, out of 1150 studies preselected, were included. We found that paediatricians show more appropriate pharmacology prescription patterns for the illness being treated; they achieve higher vaccination rates and have better knowledge of vaccines and fewer doubts about vaccine safety; their knowledge and implementation of different screening tests are better; they prescribe psychoactive drugs more cautiously and more in line with current practice guidelines; their evaluation and treatment of obesity and lipid disorders follow criteria more consistently with current clinical practice guidelines; and they perform fewer diagnostic test, show a more suitable use of the test and request fewer referrals to specialists. Conclusion: According to published data, in developed countries, paediatricians provide higher quality care to children than family doctors

Desarrollo de dispositivos semiconductores basados en películas delgadas

IP 1101-05-025-92with multilayer structure / G. Gordillo, J. Torres. -- En:ThinSolid Films. -- Vol. 310 (1997); p. 310-316.;'-- Efecto de La temperatura del sustrato sobre La respuesta espectral de fotoconductores basados en peliculas;delgadas de compuestos II-VI (Zn, Cd and S) / G. Gordillo,J.Torres. -- En: Revista Colombiana de fisica. --;Vol. 29, no 2 (1997); p. 131-134. -- Caracterizacion electricade peliculas delgadas semiconductoras de ZnO,;Zno:F y ZnO: Au/Pd / G. Gordillo. ... [et. al]. -- En: RevistaColombianade fisica. -- Vol. 29, no. 2 (1997);p. 139-142. -- Medidas de la respuesta espectral de celdassolares de peliculas delgadas de SnO2/CdS/CdTe / G.;Gordillo, W. de la Cruz. -- En: Revista Colombiana de fisica.--Vol. 29,no. 2 (1997); p. 123-126. --;PONENCIA(S) EN CONGRESO: Surface segregation in CuInSe2 thin films / G. Gordillo, P. Teheran, L. Cota. -- En:;European Photovoltaic Solar energy Conference (1995 Oct :413287: Nice, France). -- Nice, 1999. -- p. -- 28;cm.;ARTICULO(S) EN REVISTA: Preparation and characterization of SnO2thin films deposited by spray pyrolysis;from SnCl4 precursors / G. Gordillo. ... [et. al]. -- En:thinSolid Films. -- Vol. 252 (1994); p. 61-66. --;Preparacion y caracterizacion de peliculas delgadas de CdSdepositadas porel metodo CBD (chemical bath;deposition) / L. Moreno. ... [et. al]. -- En: Revista Colombianade Fisica. -- Vol. 27 (1995); p. 463-466. --;A simple method to determine the optical constants and thicknesses of ZnxCd1-xS thin films / G. Gordillo. ...;[et. al]. En: Thin Solid Films. -- Vol. 289 (1996); p. 238-241.'-- Determination of the optical constants of;policrystalline CdS thin films prepared by evaporation / G. Gordillo. ...[et. al] . -- En: Advances in;Materials Science y Technology. -- Vol. 1, no. 1 (1996); p. 7-12. -- ISSN13162012. -- Preparation and;characterization of CdTe thin films deposited by CSS / G.Gordillo, J. M.Florez, L. C. Hernandez. -- En:;Solar Energy Materials and Solar Cells. -- Vol. 37 (1995);p.273-281. --Evolution of the phases and chemical;composition during the formation of CIS thin films prepared byinterdiffusion process in selenides layers / G.;Gordillo. -- [et. al]. -- En: Journal of cristal Growth. -'- Vol.183 (1998); p. 352-360. -- CuInSe2:;estructura multicapa y sensores de gases tipo taguchi, fabricados con peliculas delgadas de ZnO depositadas;Journal of Physics. -- Vol. 26, no. 1 (Mar. 1996); p. 274-276.-'- Effect of gas chemisorption on the;electrical conductivity of ZnO thin films / G. Gordillo, C. Calderon. -- En: Materials Science y Technology.; Vol. 1, no. 1 (1996); p. 01-05. -- Photoconductors basedonZnxCd1_xS and CdSe1_ySy thin films, fabricate

Surgical site infection after gastrointestinal surgery in children : an international, multicentre, prospective cohort study

Introduction Surgical site infection (SSI) is one of the most common healthcare-associated infections (HAIs). However, there is a lack of data available about SSI in children worldwide, especially from low-income and middle-income countries. This study aimed to estimate the incidence of SSI in children and associations between SSI and morbidity across human development settings. Methods A multicentre, international, prospective, validated cohort study of children aged under 16 years undergoing clean-contaminated, contaminated or dirty gastrointestinal surgery. Any hospital in the world providing paediatric surgery was eligible to contribute data between January and July 2016. The primary outcome was the incidence of SSI by 30 days. Relationships between explanatory variables and SSI were examined using multilevel logistic regression. Countries were stratified into high development, middle development and low development groups using the United Nations Human Development Index (HDI). Results Of 1159 children across 181 hospitals in 51 countries, 523 (45 center dot 1%) children were from high HDI, 397 (34 center dot 2%) from middle HDI and 239 (20 center dot 6%) from low HDI countries. The 30-day SSI rate was 6.3% (33/523) in high HDI, 12 center dot 8% (51/397) in middle HDI and 24 center dot 7% (59/239) in low HDI countries. SSI was associated with higher incidence of 30-day mortality, intervention, organ-space infection and other HAIs, with the highest rates seen in low HDI countries. Median length of stay in patients who had an SSI was longer (7.0 days), compared with 3.0 days in patients who did not have an SSI. Use of laparoscopy was associated with significantly lower SSI rates, even after accounting for HDI. Conclusion The odds of SSI in children is nearly four times greater in low HDI compared with high HDI countries. Policies to reduce SSI should be prioritised as part of the wider global agenda.Peer reviewe

The Spanish version of Face-Name Associative Memory Exam (S-FNAME) performance is related to amyloid burden in Subjective Cognitive Decline

The Face-Name Associative Memory Exam (FNAME) is a paired associative memory test created to detect memory deficits in individuals with preclinical Alzheimer’s disease (AD). Worse performance on FNAME in cognitively healthy individuals were found related to higher amyloid beta (Aβ) burden measured with Positron-Emission-Tomography using 11C-PiB (PiB-PET). We previously reported normative data of a Spanish version of FNAME (S-FNAME) in cognitively healthy Spanish-speaking subjects. The aim of the present study was to determine whether performance on S-FNAME was associated with Aβ burden in subjective cognitive decline (SCD) individuals. 200 SCD subjects received neurological and neuropsychological assessments, including the S-FNAME and the Word List task from the Wechsler-Memory-Scale-III (WMS-III). Moreover, they received an MRI and (18)F-Florbetaben Positron-Emission-Tomography (FBB-PET) to measure Aβ burden. Three cognitive factor composites were derived for the episodic memory measures (face-name [SFN-N], face-occupation [SFN-O] and WMS-III) to determine whether episodic memory performance was related to Aβ deposition. Higher global Aβ deposition was significantly related to worse performance on SFN-N but not with SFN-O or WMS-III Composite. Moreover, worse SFN-N performance was significantly related to higher Aβ deposition in bilateral Posterior Cingulate Cortex. The S-FNAME may be a promising neuropsychological tool for detecting SCD individuals with preclinical AD

Catálogo de los recursos pesqueros continentales de Colombia

El documento que presentamos al público tiene una importancia tanto para la academia y centros de investigación como para las autoridades, tomadores de decisiones y el público en general, en aras de la generación de una conciencia colectiva sobre la problemática asociada a los recursos pesqueros y la necesidad de tomar medidas urgentes para su aprovechamiento sostenible por el bien común. En este contexto, el “Catalogo de los recursos pesqueros continentales de Colombia” contiene la información científicamente válida que ha llevado a establecer que las especies de peces de consumo y en consecuencia con alto valor comercial en aguas continentales son 173, cifra que probablemente se ampliará con futuros estudios y nuevos datos. De las especies listadas, 31 se encuentran categorizadas con algún grado de amenaza, siendo precisamente la causa el aprovechamiento derivado de su valor comercial, y que de continuar el aprovechamiento descontrolado, a la brevedad estaremos presenciando su extinción.Bogotá, D. C