244 research outputs found

    Mediation Effect of Lean: A Bidirectional Synergetic Relationship with SCM for Higher Operational Performance

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    Competitive plants focus their efforts on reducing manufacturing costs and waste along their production chains. Hence, manufacturing programs with important practices and methodologies such as lean, JIT, TPM, and Kaizen have been embraced. However, an empirical investigation of simultaneous use of several manufacturing programs representing multiple facets of lean is lacking in the literature. Various studies have found that some supply chain management practices are bi-directionally related to lean, but its holistic measurement in relation to supply chain management is still lacking. Thus, this paper provides an evidence of mediation effect of lean from high performance manufacturing (HPM) project perspective in relation to supply chain management

    Iron profile and hepcidin associated with oxidative stress and metabolic disturbances in pregnancy

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    Background: A common problem during pregnancy is anemia and to reduce its prevalence the WHO and national guidelines recommend a prescription of 30 to 60 mg of iron/day. The aim of this study was to evaluate the association of iron profile, hepcidin and oxidative stress in pregnant women prescribed with iron as a probable cause of metabolic disorders. Method: In this cohort study two groups were followed: A) women with low-risk pregnancy (WLRP), B) women with high-risk pregnancy (WHRP): women with metabolic disorders (dyslipidemias, GDM and high blood pressure). Oxidative stress enzymes, iron profile and hepcidin were measured in the second and third trimesters. Results: There were significant differences in hepcidin levels between WLRP and WHRP in 2nd (3.6 ± 4.2 vs 4.69 ± 3.23 P=0.005) and 3rd trimester (3.65 ± 3.44 vs 6.84 ± 5.14 P=0.02). The serum iron concentration had a negative relationship with catalase (-0.599; P=0.04) and a positive relationship with glutathione peroxidase (0.729; P=0.007). Conclusion: The iron serum levels increase could induce oxidative damage in pregnancy. Increased hepcidin is a useful biomarker for determining iron availability in pregnancy and its association with antioxidant systems

    Comparative Mechanical Study of Pressure Sensitive Adhesives over Aluminium Substrates for Industrial Applications

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    The use of adhesives for fixing low-weight elements is showing increasing interest in the industry, as it would reduce the weight of the assembly, costs, and production time. Specifically, the application of pressure-sensitive adhesives (PSAs) to join non-structural naval components to aluminium substrates has not yet been reported. In the present work, a study of the mechanical behaviour of different double-sided PSAs applied on bare aluminium alloy substrates is performed. The influence of surface roughness, surface chemical treatments, and the matrix of the adhesives is studied through different mechanical tests, such as shear, T-peel, and creep. The application of an adhesion promoter improved the mechanical behaviour. Low roughness substrates provided better performance than ground samples. Acrylic foam adhesives were subjected to creep tests, whose results were fitted to a simple mathematical model, predicting the fracture time as a function of the applied load

    Dosis acumulada de radiación en tomografía computarizada en pacientes atendidos en el Hospital Vicente Corral Moscoso, Cuenca, año 2019

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    Antecedentes: la tomografía axial computarizada es un estudio diagnóstico de imagen ampliamente utilizado durante los últimos años por su alta especificidad, sin embargo, la exposición a la radiación ionizante ha generado controversias en el personal médico por los posibles daños o mutaciones que este pudiese causar en el tejido. Objetivo: determinar la dosis de radiación en tomografía computarizada en pacientes atendidos en el Hospital Vicente Corral Moscoso durante el año 2019. Materiales y métodos: se trata de un estudio retrospectivo de cohorte transversal. Se incluyeron 296 expedientes clínicos de pacientes que cumplieron los criterios de inclusión. La información fue analizada mediante el programa estadístico SPSS versión 15.0, aplicándose estadística descriptiva. Resultados: 72% de pacientes se realizaron tomografías simples y 49.3% contrastadas. Las regiones anatómicas más estudiadas fueron las estructuras de cabeza y cuello con 65.9%. El 90.9% de los casos que se realizaron TC simple y contrastada, la dosis efectiva de radiación fue baja (0-50 mSV); en las personas en las que se efectúo solo TC simple, en el 4.4% se categorizó como riesgo medio y un 2.4% alto; y en los participantes que se sometieron a TC contrastada, el 2.7% y 2% se consideraron como riesgo medio y alto respectivamente. Según la radiación acumulada, 81.4% presentaron riesgo bajo; en la TC simple el 8.4% riesgo medio en contraste con 7.4% de la TC contrastada y 4.7% versus 3.7% de riesgo alto en la TC simple y contrastada respectivamente.Background: computerized axial tomography is a diagnostic imaging study widely used in recent years due to its high specificity, however, exposure to ionizing radiation has generated controversy among medical personnel due to possible damage or mutations that it could cause in the tissue. Objective: to determine the radiation dose in computed tomography in patients treated at the Vicente Corral Moscoso Hospital during the year 2019. Materials and methods: this is a retrospective cross-sectional cohort study. 296 clinical records of patients who met the inclusion criteria were included. The information was analyzed using the statistical program SPSS version 15.0, applying descriptive statistics. Results: 72% of patients underwent simple tomographies and 49.3% contrasted. The most studied anatomical regions were the head and neck structures with 65.9%. In 90.9% of the cases that underwent simple and contrast CT, the effective dose of radiation was low (0-50 mSV); in the people in whom only a simple CT was performed, 4.4% were categorized as medium risk and 2.4% high; and in participants who underwent contrast-enhanced CT, 2.7% and 2% were considered medium and high risk respectively. According to the accumulated radiation, 81.4% presented low risk; in simple CT 8.4% medium risk in contrast to 7.4% in contrast-enhanced CT and 4.7% versus 3.7% high risk in simple and contrast-enhanced CT respectively.0009-0001-8441-6980Especialista en ImagenologíaCuenc

    Estrategias didácticas: dificultad o fortaleza en el aprendizaje de los estudiantes en el trabajo con fracciones algebraicas

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    El propósito de esta investigación es establecer las fortalezas y debilidades que traen consigo las diferentes estrategias que utilizan los docentes en el proceso de enseñanza y aprendizaje, con respecto a la formulación y desarrollo de operaciones con fracciones

    A method to correct nasal valve dysfunction

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    El colapso valvular es una causa común de obstrucción respiratoria. Presentamos el caso clínico de una mujer de 62 años con obstrucción nasal derecha. En la exploración física se observó la existencia de una estenosis de vávula nasal de predominio derecho. Se realizó la corrección quirúrgica de la misma mediante la suspensión valvular con hilos de sutura, utilizando una variación de la técnica de Paniello, obteniendo resultados satisfactorios desde la finalización de la cirugía. Proponiéndose esta técnica como una alternativa inicial a los diferentes métodos de corrección quirúrgica existentes hasta el momentoThe nasal alar collapse is a common cause of respiratory obstruction. We report the case of 62 years woman with right nasal obstruction. Physical examination reveals the existence of nasal valve stenosis with right predominance. Surgical correction is performed by the valve suspension with surgical thread, using a variation of the Paniello´s technique, obtaining satisfactory results from the completion of surgery. This technique is proposed as an alternative to the different surgical techniques existing to dat
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