505 research outputs found

    Uma escola para a saúde

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    O livro apresenta os caminhos percorridos na direção da profissionalização e da especialização em saúde pública no Brasil, refletindo as influências e iniciativas nacionais e internacionais.na criação da Escola Nacional de Saúde Pública (Ensp), em 1954. Nesse laboratório de idéias em que se constituiu a Escola, formularam-se propostas que contribuíram para as grandes conquistas da saúde pública brasileira e que subsidiaram o processo de Reforma Sanitária, cujos resultados se expressam na constituição e no fortalecimento do SUS. Organizado em duas partes, na primeira é apresentado um texto narrativo sucinto sobre a Ensp, desde a sua criação até os anos recentes. A segunda, traz artigos sobre temas relevantes para o entendimento da história da Ensp e de seu papel na saúde pública contemporânea

    Mídia, imagem e cultura - Vivências de extensão universitária

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    EDUFTQual é o Tocantins que temos vivido e experimentado? O livro busca responder esta questão, que conecta os participantes do projeto de extensão Mídia, Imagem e Cultura, desenvolvido pelos grupos Coletivo 50 graus: pesquisa e prática fotográfica e CID: Comunicação, Imagem e Diversidade Cultural, da Universidade Federal do Tocantins. Explora as experiências dos extensionistas com fotografia experimental, produção de audiovisual e oficinas. O projeto foi financiado pelo Edital PROEX/UFT 2019 e teve apoio do Programa de Pós-Graduação em Comunicação e Sociedade e dos cursos de Pedagogia e Jornalismo da UFT

    Tecnologias digitais na educação

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    Tecnologias Digitais na Educação apresenta uma seleção de artigos que são resultado das monografias da primeira turma do curso de Especialização em Novas Tecnologias na Educação

    Relatório de gestão 2003: Embrapa Uva e Vinho.

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    bitstream/CNPUV/8153/1/doc043.pd

    Polymorphisms in the WNK1 gene are asociated with blood pressure variation and urinary potassium excretion

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    WNK1 - a serine/threonine kinase involved in electrolyte homeostasis and blood pressure (BP) control - is an excellent candidate gene for essential hypertension (EH). We and others have previously reported association between WNK1 and BP variation. Using tag SNPs (tSNPs) that capture 100% of common WNK1 variation in HapMap, we aimed to replicate our findings with BP and to test for association with phenotypes relating to WNK1 function in the British Genetics of Hypertension (BRIGHT) study case-control resource (1700 hypertensive cases and 1700 normotensive controls). We found multiple variants to be associated with systolic blood pressure, SBP (7/28 tSNPs min-p = 0.0005), diastolic blood pressure, DBP (7/28 tSNPs min-p = 0.002) and 24 hour urinary potassium excretion (10/28 tSNPs min-p = 0.0004). Associations with SBP and urine potassium remained significant after correction for multiple testing (p = 0.02 and p = 0.01 respectively). The major allele (A) of rs765250, located in intron 1, demonstrated the strongest evidence for association with SBP, effect size 3.14 mmHg (95%CI:1.23–4.9), DBP 1.9 mmHg (95%CI:0.7–3.2) and hypertension, odds ratio (OR: 1.3 [95%CI: 1.0–1.7]).We genotyped this variant in six independent populations (n = 14,451) and replicated the association between rs765250 and SBP in a meta-analysis (p = 7×10−3, combined with BRIGHT data-set p = 2×10−4, n = 17,851). The associations of WNK1 with DBP and EH were not confirmed. Haplotype analysis revealed striking associations with hypertension and BP variation (global permutation p10 mmHg reduction) and risk for hypertension (OR<0.60). Our data indicates that multiple rare and common WNK1 variants contribute to BP variation and hypertension, and provide compelling evidence to initiate further genetic and functional studies to explore the role of WNK1 in BP regulation and EH

    One-Year Risk of Stroke after Transient Ischemic Attack or Minor Stroke

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    BACKGROUND Previous studies conducted between 1997 and 2003 estimated that the risk of stroke or an acute coronary syndrome was 12 to 20% during the first 3 months after a transient ischemic attack (TIA) or minor stroke. The TIAregistry.org project was designed to describe the contemporary profile, etiologic factors, and outcomes in patients with a TIA or minor ischemic stroke who receive care in health systems that now offer urgent evaluation by stroke specialists. METHODS We recruited patients who had had a TIA or minor stroke within the previous 7 days. Sites were selected if they had systems dedicated to urgent evaluation of patients with TIA. We estimated the 1-year risk of stroke and of the composite outcome of stroke, an acute coronary syndrome, or death from cardiovascular causes. We also examined the association of the ABCD2 score for the risk of stroke (range, 0 [lowest risk] to 7 [highest risk]), findings on brain imaging, and cause of TIA or minor stroke with the risk of recurrent stroke over a period of 1 year. RESULTS From 2009 through 2011, we enrolled 4789 patients at 61 sites in 21 countries. A total of 78.4% of the patients were evaluated by stroke specialists within 24 hours after symptom onset. A total of 33.4% of the patients had an acute brain infarction, 23.2% had at least one extracranial or intracranial stenosis of 50% or more, and 10.4% had atrial fibrillation. The Kaplan–Meier estimate of the 1-year event rate of the composite cardiovascular outcome was 6.2% (95% confidence interval, 5.5 to 7.0). Kaplan–Meier estimates of the stroke rate at days 2, 7, 30, 90, and 365 were 1.5%, 2.1%, 2.8%, 3.7%, and 5.1%, respectively. In multivariable analyses, multiple infarctions on brain imaging, large-artery atherosclerosis, and an ABCD2 score of 6 or 7 were each associated with more than a doubling of the risk of stroke. CONCLUSIONS We observed a lower risk of cardiovascular events after TIA than previously reported. The ABCD2 score, findings on brain imaging, and status with respect to large-artery atherosclerosis helped stratify the risk of recurrent stroke within 1 year after a TIA or minor stroke. (Funded by Sanofi and Bristol-Myers Squibb.)Supported by an unrestricted grant from Sanofi and Bristol-Myers Squibb

    Finding the niche: A review of market assessment methodologies for rural electrification with small scale wind power

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    The mass roll out of solar PV across the Global South has enabled electricity access for millions of people. In the right context, Small Wind Turbines (SWTs) can be complementary, offering the potential to generate at times of low solar resource (night, monsoon season, winter, etc.) and increasing the proportion of the total energy system that can be manufactured locally. However, many contextual factors critically affect the viability of the technology, such as the extreme variability in the wind resource itself and the local availability of technical support. Therefore, performing a detailed market analysis in each new context is much more important. The Wind Empowerment Market Assessment Methodology (WEMAM) is a multi-scalar, transdisciplinary methodology for identifying the niche contexts where small wind can make a valuable contribution to rural electrification. This paper aims to inform the development of WEMAM with a critical review of existing market assessment methodologies. By breaking down WEMAM into its component parts, reflecting upon its practical applications to date and drawing upon insights from the literature, opportunities where it could continue to evolve are highlighted. Key opportunities include shifting the focus towards development outcomes; creating community archetypes; localised studies in high potential regions; scenario modelling and MCDA ranking of proposed interventions; participatory market mapping; and applying socio-technical transitions theory to understand how the small wind niche can break through into the mainstream

    Належна організація корпоративного управління як спосіб попердження конфліктних ситуацій в акціонерному товаристві

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    Жорнокуй, Ю. М. Належна організація корпоративного управління як спосіб попердження конфліктних ситуацій в акціонерному товаристві / Юрій Жорнокуй // 25 років становлення Сумської філії Харківського національного університету внутрішніх справ: славетна історія та горизонти майбутнього: матеріали Міжнар. наук.-практ. конф. (м. Суми, 21-22 лютого 2020 р.) / МВС України, Сумська філія Харківського національного університету внутрішніх справ. – Суми: Видавничий дім «Ельдорадо», 2020. – С. 46-48Розглядається питання щодо недопущення порушення корпоративних прав акціонерів, необхідність використання принципів корпоративного управління для попередження виникнення корпоративних конфліктів та забезпечення належної корпоративної поведінкиThe issues of preventing the violation of corporate rights of shareholders, the need to use the principles of corporate governance to prevent corporate conflicts and ensure proper corporate behavior are consideredРассматривается вопрос недопущения нарушения корпоративных прав акционеров, необходимость использования принципов корпоративного управления для предупреждения возникновения корпоративных конфликтов и обеспечения надлежащего корпоративного поведени

    Перегляд судових рішень за нововиявленими обставинами

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    Соловйова, Л. М. Перегляд судових рішень за нововиявленими обставинами / Людмила Михайлівна Соловйова // Актуальні проблеми правової науки і державотворення в Україні в контексті правової інтеграції : матеріали ХІ Міжнародної науково-практичної конференції (18-19 травня 2018 року, м. Суми) / Сумська філія Харківського національного університету внутрішніх справ. – Суми: Видавничий дім «Ельдорадо», 2018. – С. 108-110.До Кримінального процесуального кодексу було введено прогресивні зміни у перегляд судових рішень у зв’язку з нововиявленими обставинами. Однак, незважаючи на це, залишається ще низка проблем, які потребують відповідного реагування з боку органів, яким надано право законодавчої ініціативи для усунення прогалин та колізій у встановленому порядку для цього виду провадження.Progressive changes were introduced to the Criminal Procedure Code in the review of court decisions in connection with newly discovered circumstances. However, despite this, there are still a number of problems that require an appropriate response from the bodies that have been granted the right of legislative initiative to eliminate gaps and conflicts in the established procedure for this type of proceeding.В Уголовный процессуальный кодекс были введены прогрессивные изменения в пересмотр судебных решений в связи с вновь открывшимися обстоятельствами. Однако, несмотря на это, остается еще ряд проблем, требующих соответствующего реагирования со стороны органов, которым предоставлено право законодательной инициативы по устранению пробелов и коллизий в установленном порядке для этого вида производства
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