Embedded AGN and star formation in the central 80 pc of IC 3639

[Abridged] Methods: We use interferometric observations in the $N$-band with VLTI/MIDI to resolve the mid-IR nucleus of IC 3639. The origin of the nuclear infrared emission is determined from: 1) the comparison of the correlated fluxes from VLTI/MIDI with the fluxes measured at subarcsec resolution (VLT/VISIR, VLT/ISAAC); 2) diagnostics based on IR fine-structure line ratios, the IR continuum emission, IR bands produced by polycyclic aromatic hydrocarbons (PAH) and silicates; and 3) the high-angular resolution spectral energy distribution. Results: The unresolved flux of IC 3639 is $90 \pm 20\, \rm{mJy}$ at $10.5\, \rm{\mu m}$, measured with three different baselines in VLTI (UT1-UT2, UT3-UT4, and UT2-UT3; $46$-$58\, \rm{m}$), making this the faintest measurement so far achieved with mid-IR interferometry. The correlated flux is a factor of $3$-$4$ times fainter than the VLT/VISIR total flux measurement. The observations suggest that most of the mid-IR emission has its origin on spatial scales between $10$ and $80\, \rm{pc}$ ($40$-$340\, \rm{mas}$). A composite scenario where the star formation component dominates over the AGN is favoured by the diagnostics based on ratios of IR fine-structure emission lines, the shape of the IR continuum, and the PAH and silicate bands. Conclusions: A composite AGN-starburst scenario is able to explain both the mid-IR brightness distribution and the IR spectral properties observed in the nucleus of IC 3639. The nuclear starburst would dominate the mid-IR emission and the ionisation of low-excitation lines (e.g. [NeII]$_{12.8 \rm{\mu m}}$) with a net contribution of $\sim 70\%$. The AGN accounts for the remaining $\sim 30\%$ of the mid-IR flux, ascribed to the unresolved component in the MIDI observations, and the ionisation of high-excitation lines (e.g. [NeV]$_{14.3 \rm{\mu m}}$ and [OIV]$_{25.9 \rm{\mu m}}$).Comment: Accepted for publication in A&

Far-infrared line spectra of active galaxies from the Herschel/PACS Spectrometer: the complete database

We present a coherent database of spectroscopic observations of far-IR fine-structure lines from the Herschel/PACS archive for a sample of 170 local AGN, plus a comparison sample of 20 starburst galaxies and 43 dwarf galaxies. Published Spitzer/IRS and Herschel/SPIRE line fluxes are included to extend our database to the full 10-600 $\mu m$ spectral range. The observations are compared to a set of CLOUDY photoionisation models to estimate the above physical quantities through different diagnostic diagrams. We confirm the presence of a stratification of gas density in the emission regions of the galaxies, which increases with the ionisation potential of the emission lines. The new [OIV]25.9$\mu m$/[OIII]88$\mu m$ vs [NeIII]15.6$\mu m$/[NeII]12.8$\mu m$ diagram is proposed as the best diagnostic to separate: $i)$ AGN activity from any kind of star formation; and $ii)$ low-metallicity dwarf galaxies from starburst galaxies. Current stellar atmosphere models fail to reproduce the observed [OIV]25.9$\mu m$/[OIII]88$\mu m$ ratios, which are much higher when compared to the predicted values. Finally, the ([NeIII]15.6$\mu m$ + [NeII]12.8$\mu m$)/([SIV]10.5$\mu m$ + [SIII]18.7$\mu m$) ratio is proposed as a promising metallicity tracer to be used in obscured objects, where optical lines fail to accurately measure the metallicity. The diagnostic power of mid- to far-infrared spectroscopy shown here for local galaxies will be of crucial importance to study galaxy evolution during the dust-obscured phase at the peak of the star formation and black-hole accretion activity ($1 < z < 4$). This study will be addressed by future deep spectroscopic surveys with present and forthcoming facilities such as JWST, ALMA, and SPICA.Comment: Accepted for publication in the ApJ

Probabilistic Strain Energy Life Assessment Model

AbstractUnder the “safe-life” methodology used by the United States Navy the service life of aircraft fleet are determined by monitoring the aircraft's usage and estimating the respective fatigue damage. The calculated fatigue life expenditure representing cumulative damage is then used to determine if it is possible for an aircraft or a fleet of aircrafts to reach the point of crack initiation and whether or not it should be retired. This research focuses on the development and initial application of a probabilistic strain-energy model to augment the empirical-based fatigue life expended approach. Experimental fatigue data obtained in this research is used to determine the relation between the number of cycles-to-failure and the cumulative total strain energy. A Bayesian framework for regression, including consideration of the model error is used to develop a probabilistic model of life that includes parameter uncertainties due to the limitation and scatter observed in the experimental data

Producción cerámica en la edad del Bronce en Catalunya: el ejemplo de la cueva de Les Pixarelles (Osona)

La cerámica aparecida en la cueva de Les Pixarelles proporciona un conjunto ideal para estudiar la evolución de las producciones cerámicas desde la fase final del Neolítico hasta el Bronce final en Catalunya. El estudio diacrónico de las cerámicas se ha basado en la combinación del estudio tipológico y estilístico y en un estudio petrográfico que ha permitido caracterizar diversas fábricas. Las diferencias observadas responden a la utilización de diversas materias primas y a la utilización de diferentes técnicas de preparación de pasta que revelan una interesante complejidad para la producción cerámica de la zona.The ceramic found at PixareJles Cave provides an excellent assemblage to study pottery-making traditions in Catalonia from Late Neolithic to Late Bronze Age. The present study has been carried out by combining a typological and stylistical study and petrografic analysis. Several fabrics, according to composition and texture, have been characterised. These fabrics reflect the use of different raw materials -according to different raw materials procurement strategies- and different paste recipes, indicating an interesting complexity for the pottery-making traditions within the area of study

The relationship between truncation and phosphorylation at the C-terminus of tau protein in the paired helical filaments of Alzheimer's disease

Acknowledgements: Authors want to express their gratitude to Dr. P. Davies (Albert Einstein College of Medicine, Bronx, NY, USA) and Lester I. Binder (NorthWestern, Chicago, IL, USA) for the generous gift of mAbs (TG-3, Alz-50, and MC1), and (TauC-3), respectively, and to M. en C. Ivan J. Galván-Mendoza for his support in confocal microscopy, and Ms. Maricarmen De Lorenz for her secretarial assistance. We also want to express our gratitude to the Mexican Families who donate the brain of their loved ones affected with Alzheimer's disease, and made possible our research. This work was financially supported by CONACyT grant, No. 142293 (For R.M).Peer reviewedPublisher PD

The 1989 and 2015 outbursts of V404 Cygni: a global study of wind-related optical features

The black hole transient V404 Cygni exhibited a bright outburst in June 2015 that was intensively followed over a wide range of wavelengths. Our team obtained high time resolution optical spectroscopy (~90 s), which included a detailed coverage of the most active phase of the event. We present a database consisting of 651 optical spectra obtained during this event, that we combine with 58 spectra gathered during the fainter December 2015 sequel outburst, as well as with 57 spectra from the 1989 event. We previously reported the discovery of wind-related features (P-Cygni and broad-wing line profiles) during both 2015 outbursts. Here, we build diagnostic diagrams that enable us to study the evolution of typical emission line parameters, such as line fluxes and equivalent widths, and develop a technique to systematically detect outflow signatures. We find that these are present throughout the outburst, even at very low optical fluxes, and that both types of outflow features are observed simultaneously in some spectra, confirming the idea of a common origin. We also show that the nebular phases depict loop patterns in many diagnostic diagrams, while P-Cygni profiles are highly variable on time-scales of minutes. The comparison between the three outbursts reveals that the spectra obtained during June and December 2015 share many similarities, while those from 1989 exhibit narrower emission lines and lower wind terminal velocities. The diagnostic diagrams presented in this work have been produced using standard measurement techniques and thus may be applied to other active low-mass X-ray binaries.Comment: Accepted for publication in MNRAS. 23 pages paper, plus a 9 pages appendix with extra tables and figures. 18 figures are included in the paper and 8 in the appendi

Cardiac Effects of a Single Dose of Pimobendan in Cats With Hypertrophic Cardiomyopathy; A Randomized, Placebo-Controlled, Crossover Study

Background: Pimobendan has been shown to impart a significant survival benefit in cardiomyopathic cats who receive it as part of heart failure therapy. However, use of pimobendan remains controversial in cats with hypertrophic cardiomyopathy (HCM) due to lack of pharmacodynamic data for pimobendan in cats with HCM and due to theoretical concerns for exacerbating left ventricular outflow tract obstructions. Hypothesis/Objectives: Our objective was to investigate the cardiac effects of pimobendan in cats with HCM. We hypothesized that pimobendan would not exacerbate left ventricular outflow tract obstructions and that it would improve echocardiographic measures of diastolic function. Animals: Thirteen purpose-bred cats were studied from a research colony with naturally-occurring HCM due to a variant in myosin binding protein C. Methods: Cats underwent two examinations 24 h apart with complete standard echocardiography. On their first day of evaluation, they were randomized to receive oral placebo or 1.25 mg pimobendan 1 h prior to exam. On their second examination, they were crossed over and received the remaining treatment. Investigators were blinded to all treatments. Results: The pimobendan group had a significant increase in left atrial fractional shortening (pimobendan group 41.7% ± 5.9; placebo group 36.1% ± 6.0; p = 0.04). There was no significant difference in left ventricular outflow tract (LVOT) velocities between the groups (pimobendan group 2.8 m/s ± 0.8; placebo group 2.6 m/s ± 1.0). There were no significant differences between the number of cats with LVOT obstructions between groups (12 in pimobendan group; 11 in placebo group; p = 1.00). There were no detectable differences in any systolic measures, including left ventricular fractional shortening, mitral annular plane systolic excursion, and tricuspid annular plane systolic excursion. Doppler-based diastolic function assessment was precluded by persistent tachycardia. Conclusions: Improved left atrial function in the pimobendan group could explain some of the reported survival benefit for HCM cats in CHF. Pimobendan did not exacerbate LVOT obstructions and thus may not be contraindicated in HCM cats with LVOT obstructions. Future studies are needed to better characterize other physiologic effects, particularly regarding diastolic function assessment, and to better assess safety of pimobendan over a longer time-course.Center for Companion Animal Health at the University of California Davis, School of Veterinary Medicine [2016-15-F]Open access journalThis item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at [email protected]

CONOCIMIENTO DE ENFERMERÍA EN EL CUIDADO DE PACIENTES DIABÉTICOS ANTES Y DESPUÉS DE UNA INTERVENCIÓN EDUCATIVA.

Introduction: The constantly education of anybody profession, in special the nursery advance with the professionals diferents stamentsneeds a permanent plan of formation. If we set a real commitment with transformation on labor and social practice, as the quality of the attention; this plan cannot be conceived without integrating the institutions of effective performance. Objetive: To compare the degree of Knowledges of the nursing personal of the education Model in Diabetes Mellitus for the health before and after of a educative intervatiun. Material and methods: It is realized comparative research before and after to 25 nurses, them to attend to the educative intervatiun, it was the model capacitation in Diabetes Mellitus of the health education using didactics strategists. That permitted to personal having more participation, of the one hour 30 minutes, each one. The instrument elaborated of an examination structured with question of options multiples and false and true, with a value 70% o the items, and a clinical case of diabetic patient with a value of 30%. Result: The middle of age of the student population was to 38 years, with a DE plus 5.3 about to the degree of Knowledges to the infirmary personal of the education model for the health education before of the educative intervatiun. The 80% was low. After of theintervatiun to winnowen 72% high. With proof of the hypothesis of WILCOXON = with value PO. 05. Conclusions: The effect of the educative intervatiun was significant statistically, for the sake of the degree of knowledges to education model in Diabetes Mellitus for the health was bigger after to the intervatiun.Introducción: La Educación permanente de cualquier profesión, en especial el avance en enfermería con sus distintos estamentos de profesionales, requiere de un plan permanente de formación. Si se plantea un compromiso real con la transformación en la práctica laboral y social, así como con la calidad de la atención, dicho plano no puede concebirse sin integrar a las instituciones de desempeño efectivo. Objetivo: Comparar el grado de conocimientos del personal de enfermería del modelo educación para la salud en Diabetes Mellitus antes y después de una intervención educativa. Material y métodos: Se realizó estudio comparativo antes y después, a 25 enfermeras, las cuales asistieron a la intervención educativa de capacitación del modelo de Educación para la Salud en Diabetes Mellitus, utilizando estrategias didácticas que permitieron al personal tener mayor participación. En total se desarrollaron 15 sesiones de hora y media cada una. El instrumento se elaboró a través de un examen estructurado con preguntas de opción múltiple y falso y verdadero con un valor del 70% de los ítems y un caso clínico de paciente diabético con un valor de 30% de lo ítems. Resultados: El promedio de edad de la población estudiada fue de 38 años, con una DE +5.3. Referente al grado de conocimiento del personal de enfermería del Modelo de Educación para la Salud antes de la intervención educativa, el 80% salió BAJO. Después de la intervención arrojó el 72% ALTO. Con prueba WLCOXON = con valor P < 0.05. Conclusiones: El efecto de la intervención educativa fue estadísticamente significativa; por lo que el grado de conocimientos del modelo de Educación para la Salud en Diabetes Mellitus fue mayor después de la intervención

Gestão do conhecimento e competitividade na indústria aeroespacial: Um estudo de caso em Querétaro, México

This article analyzes the role of knowledge management in the competitiveness of the aerospace industry. It uses a quantitative methodology of correlational scope. A company from section 33641 of the Classification System for North America -SCIAN is being studied. A questionnaire of 24 items valued with a Likert scale (Cronbach's Alpha = .945, knowledge management = .927, and competitiveness =.915) was applied, aimed at company personnel in 3 key areas: Management, operational, and support personnel. The work studies knowledge management from Probst's theoretical proposal and competitiveness from the Competitiveness Map of the Inter-American Development Bank. The results show a moderate relationship between knowledge management processes and the company's competitiveness. Some limitations are observed due to the type of organizational structure and the high-tech processes that the company develops.Este artículo analiza el papel de la gestión del conocimiento en la competitividad de la industria aeroespacial. Utiliza una metodología cuantitativa de alcance correlacional. Se estudia una empresa del apartado 33641 del Sistema de Clasificación para América del Norte (SCIAN). Se aplicó un cuestionario de 24 ítems valorados con escala Likert (Alpha de Cronbach = .945, gestión del conocimiento = .927 y competitividad = .915) dirigido al personal de la empresa en 3 rubros clave: personal directivo, operativo y de soporte. La gestión del conocimiento se estudia desde la propuesta teórica de Probst; la competitividad, desde el Mapa de Competitividad del Banco Interamericano de Desarrollo. Los resultados encontrados exhiben una relación moderada entre los procesos de gestión del conocimiento y la competitividad de la empresa. Se observan limitaciones por el tipo de estructura organizativa y los procesos de alta tecnología que desarrolla la empresa.Este artigo analisa o papel da gestão do conhecimento na competitividade da indústria aeroespacial. Utiliza uma metodologia quantitativa de abrangência correlacional. Está em estudo uma empresa da seção 33641 do Sistema de Classificação para a América do Norte -SCIAN. Aplicou-se um questionário de 24 itens valorados com uma escala de Likert (alpha de Cronbach = .945, gestão do conhecimento = .927 e competitividade = .915) dirigido a colaboradores da empresa em 3 áreas chave: pessoal de gestão, operacional e de apoio. O trabalho estuda a gestão do conhecimento a partir da proposta teórica do Probst e a competitividade a partir do Mapa de Competitividade do Banco Interamericano de Desenvolvimento. Os resultados mostram uma relação moderada entre os processos de gestão do conhecimento e a competitividade da empresa. Algumas limitações são observadas devido ao tipo de estrutura organizacional e aos processos de alta tecnologia que a empresa desenvolve