Quality of Life of Women with Breast Cancer in Radiation and Isotopes Center

Introduction : Worldwide breast cancer is the most common cancer among females, It is the leading cause of death in the developing countries. Diagnosis of breast cancer has major impact on women quality of life, especially with advances in treatment modalities and disease-free survival the number of young survivors increased. Objective: To assess quality of life in Sudanese patients diagnosed with breast cancer in Radiation and Isotopes Center, Khartoum. Materials and Methods: A descriptive cross sectional hospital based study Radiation and Isotopes Center, Khartoum. 167 patients diagnosed with breast cancer pre- operative and post-operative receiving chemotherapy were included and interviewed using the Arabic version of SF-36 Quality of life standard questionnaire. Analysis was done with SPSS version 25. Results : 52.7% were more than 50 years of age, 43.1% had low monthly income. 70.7% underwent surgical treatment, 29% of patients started first with chemotherapy. 55.1% underwent mastectomy and 15.6% underwent breast conserving surgery. The best score was for role limitation due to emotional health with 94.6% had good score (Mean 2.8 ,SD 0.45 ). The worst score was for role limitation due to physical health with 66.5% had bad score (Mean1.6 ,SD 0.9).Social activities was extremely affected in 31.1% of patients. There is no difference in quality of life between patients treated with mastectomy versus those treated with breast conserving surgery in all domains except for social functioning which is better for mastectomy patients (p. value is 0.01). Conclusion: The overall quality of life was within the average range for most domains of quality of life, but social functioning was extremely affected. So further studies are needed with inclusion of other centers with regular follow-up to assess change in pattern of quality of life over years. Patients should be enrolled in a social support groups for better outcome

NEEDLE STICK INJURIES AMONG DENTAL STUDENTS IN ISHIK UNIVERSITY FACULTY OF DENTISTRY AND HAWLER MEDICAL COLLEGE

Background and objectives: Needle stick injuries pose a high risk to health care workers including dental students. They represent a major risk factor for transmitting blood borne pathogens including hepatitis B virus, hepatitis C virus and human immunodeficiency virus. Needles of syringes are the most commonly identified sharp object causing the injuries. Therefore, this study conducted to determine the prevalence of needle stick injuries among dental students in Ishik university facualty of dentistry and Hawler medical college. Aim and objectives of the study: The study aimed were to: 1. Find out the prevalence of NSI among dental student in Erbil cityIraq. 2. The percentage of dental students that had taken Hep B vaccine. 3. Study the knowledge of dental students regarding NSI. Subjects and method: The study was a cross sectional in nature, 114 students from Ishik University and Hawler Medical University Collage of Dentistry and data collections were done from the 1st of Dec till 2 of Feb 2018. Later on, data analysis and writing the thesis completed in May up to June, 2018. A questionnaire was completed through direct interview of the study students to measure their knowledge and practice about needle sticks injuries. All the obtained information including prevalence of needle sticks injuries, within previous 12 months, time of injury, and training on needle stick injury, knowledge, practice and attitude about needle sticks was then analyzed using statistical package for the social science software version 21. Results: The mean age of the participants was 22. The results of the study demonstrated that the prevalence of needle stick injury during past 12 months among dental students was 47,4%. Needle stick injury happened after using the needle in 35.2%, while in re-capping the needle occur in 27,8% and around 41.2% of the samples have precautions regarding NSI. Conclusion: The dental student had taken hepatitis B vaccine in a high percentage, while the prevalence of NSI was high and male showed higher prevalence than female. Training course regarding the precaution and management of NSI may need to be added to the curriculum of dental students

The Effect of Using Constructivist Teaching Approach Model on the Achievement, Creation of an Integrated Conceptual Structure and Attitudes of Al-Hussein Bin Talal University Students Towards Islamic Culture.

This study aimed at investigating the effect of A Constructional Learning Model on the achievement, creation of an Integrated Conceptual Structure and attitudes of Al-Hussein Bin Talal University students towards Islamic culture. The sample of the study consisted of 120 students at Al-Hussein Bin Talal University. The sample was divided into two groups: control and an experimental. Three tools were used in conducting this study: a) Test of Islamic culture concepts, b) Test of conceptual integration, c) and Scale of Students' attitudes towards Islamic culture course.The findings of the study were: There was a statistically significant difference between the mean cores of the experimental and control group in the test of the Islamic culture concepts in favor of the experimental group. There was a statistically significant difference between the mean scores of the experimental and control group in the test of conceptual integration in favor of the experimental group. There was a statistically significant difference between the mean scores of the experimental and control group in the students' attitudes towards the Islamic literacy in favor of the experimental group, researchers recommend the use of the constructivist learning model in teaching Islamic culture for other university students. They also recommend developing learning materials based on this model and train instructors of Islamic culture/ to use them

An overview of drug delivery vehicles for cancer treatment: Nanocarriers and nanoparticles including photovoltaic nanoparticles

Cancer is a complicated disease for which finding a cure presents challenges. In recent decades, new ways to treat cancer are being sought; one being nanomedicine, which manipulates nanoparticles to target a cancer and release drugs directly to the cancer cells. A number of cancer treatments based on nanomedicine are under way and mostly are in preclinical trials owing to challenges in administration, safety, and effectiveness. One alternative method for drug delivery is the use of photovoltaic nanoparticles,which has the potential to deliver drugs via light activation. The concepts are based on standard photovoltaic cell that holds opposite charges on its surfaces and releases drugs when charge intensity or polarity changes upon photo-stimulation such as from a laser source or sunlight. This review will cover some recent progress in cancer treatment using nanoparticles, including photovoltaic nanoparticles

Colorectal carcinoma associated with schistosomiasis: a possible causal relationship

The association between schistosomiasis and colorectal malignancy has long been suggested in the literature, but it is not uniformly accepted. In the Far East, considerable evidence supports an etiological link between Schistosoma japonicum and colorectal cancer. However, the available data regarding the role of Schistosoma mansoni in colorectal carcinogenesis are conflicting and most often do not show causality. We report on a patient with sigmoid colonic cancer coexisting with schistosomiasis, and we provide a comprehensive review of the literature regarding the epidemiology and pathobiology of this association

Graphene nanoplatelets suspended in different basefluids based solar collector: An experimental and analytical study

© 2021 by the authors. Licensee MDPI, Basel, Switzerland. A flat plate solar collector (FPSC) was analytically studied, with functionalized graphene nanoplatelets (f-GNPs) as its working fluid. Four samples (wt % nanofluids) were prepared in different base fluids such as ethylene glycol (EG), distilled water (DW):EG (70:30), and DW:EG (50:50). Experimental results (via DW) were used to verify the effectiveness of the analytical model. Some of the operating conditions were taken into account in this research, including temperatures, power, and mass flow rates. Experimental techniques were used to elucidate the modified nanofluids’ physicochemical properties, such as its particle sizes, stability, and morphology, involving electron microscopes (EMs), UV–VIS, and X-ray techniques. Differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA) were applied to test the thermal analysis. The findings confirmed that the use of f-GNPs nanofluids enhanced the performance of the FPSC relative to the use of base fluids for all testing conditions. The maximum enhancement of the collector’s effectiveness at a mass flow rate of 1.5 kg min−1 and a weight concentration of 0.1 wt %, increased to 12.69%, 12.60%, and 12.62% in the case of EG, DW:EG (70:30), and DW:EG (50:50), respectively. The results also confirmed an improvement in both the heat gain (FR(τα)) and heat loss (FRUL) coefficients for the f-GNPs nanofluid

Ozone Therapy and Hyperbaric Oxygen Treatment in Lung Injury in Septic Rats

Various therapeutic protocols were used for the management of sepsis including hyperbaric oxygen (HBO) therapy. It has been shown that ozone therapy (OT) reduced inflammation in several entities and exhibits some similarity with HBO in regard to mechanisms of action. We designed a study to evaluate the efficacy of OT in an experimental rat model of sepsis to compare with HBO. Male Wistar rats were divided into sham, sepsis+cefepime, sepsis+cefepime+HBO, and sepsis+cefepime+OT groups. Sepsis was induced by an intraperitoneal injection of Escherichia coli; HBO was administered twice daily; OT was set as intraperitoneal injections once a day. The treatments were continued for 5 days after the induction of sepsis. At the end of experiment, the lung tissues and blood samples were harvested for biochemical and histological analysis. Myeloperoxidase activities and oxidative stress parameters, and serum proinflammatory cytokine levels, IL-1β and TNF-α, were found to be ameliorated by the adjuvant use of HBO and OT in the lung tissue when compared with the antibiotherapy only group. Histologic evaluation of the lung tissue samples confirmed the biochemical outcome. Our data presented that both HBO and OT reduced inflammation and injury in the septic rats' lungs; a greater benefit was obtained for OT. The current study demonstrated that the administration of OT as well as HBO as adjuvant therapy may support antibiotherapy in protecting the lung against septic injury. HBO and OT reduced tissue oxidative stress, regulated the systemic inflammatory response, and abated cellular infiltration to the lung demonstrated by findings of MPO activity and histopathologic examination. These findings indicated that OT tended to be more effective than HBO, in particular regarding serum IL-1β, lung GSH-Px and histologic outcome

Ancient and modern DNA reveal dynamics of domestication and cross-continental dispersal of the dromedary

Dromedaries have been fundamental to the development of human societies in arid landscapes and for long-distance trade across hostile hot terrains for 3,000 y. Today they continue to be an important livestock resource in marginal agro-ecological zones. However, the history of dromedary domestication and the influence of ancient trading networks on their genetic structure have remained elusive. We combined ancient DNA sequences of wild and early-domesticated dromedary samples from arid regions with nuclear microsatellite and mitochondrial genotype information from 1,083 extant animals collected across the species’ range. We observe little phylogeographic signal in the modern population, indicative of extensive gene flow and virtually affecting all regions except East Africa, where dromedary populations have remained relatively isolated. In agreement with archaeological findings, we identify wild dromedaries from the southeast Arabian Peninsula among the founders of the domestic dromedary gene pool. Approximate Bayesian computations further support the “restocking from the wild” hypothesis, with an initial domestication followed by introgression from individuals from wild, now-extinct populations. Compared with other livestock, which show a long history of gene flow with their wild ancestors, we find a high initial diversity relative to the native distribution of the wild ancestor on the Arabian Peninsula and to the brief coexistence of early-domesticated and wild individuals. This study also demonstrates the potential to retrieve ancient DNA sequences from osseous remains excavated in hot and dry desert environments

EXAMINING AND CORRELATION ANALYZE OF THE RELATIONSHIP BETWEEN FUNCTIONAL MOVEMENT SCREENING TEST (FMS) AND UPPER LIMB FUNCTION IN ELITE BASKETBALL PLAYERS AL- RAFIDAIN SPORTS CLUB

Background Functional Movement Screening (FMS) becomes more and more popular in identifying functional limitations in basic functional movements. This experimental study was conducted to confirm the feasibility of implementing FMS among active Elite Basketball Players Al-R afidain Sports Club. The purpose of this study is to investigate the relationship between the functional sports screen (FMS) of Elite Basketball Players Al- Rafidain Sports Club and upper limb`s function Methods It is essential to have more practical and comprehensive alternatives of exercise screening for understanding human function and identifying impairments and dysfunctional exercise patterns that reduce functional quality. In many cases, weakness or tension in muscles or muscle groups is usually found, then treated with separate stretching or strengthening activities, rather than using standard exercise patterns that can solve multiple injuries at the same time. Likewise, many professionals usually focus on specific areas of complaint, rather than starting with identifying comprehensive motor characteristics and correlating that characteristic with dysfunction. The study group consisted of 60 Elite Basketball Players from Al- Rafidain Sports Club; with age between 17 and 36. Their height was 175–220 cm, weight –  65–85 kg, BMI was calculated and recorded digitally for later analysis. The inclusion criterion was absence of a history of musculoskeletal injury at least 3 months before investigation. FMS consists of 7 component tests to evaluate different basic movement modes (squat, hurdle step, overhead squat, inline lunge, shoulder flexibility, straight leg elevation test, trunk stability push-up test). Arm Disability Assessment Questionnaire (DASH) has been used to assess upper limb function as an evaluation tool for the prevention of sports injuries. Pearson correlation coefficient with significance p ≤ 0.05 was used to test the relationship between variables Resulte: The results show that there is a difference between the performance screening test scores for measuring arm disability and the high scores. (P = 0.01, R = –.068) There is a strong relationship. Conclusion It seems necessary for coaches and sports experts to choose suitable tests for athletes to prevent sports injuries. This could effectively reduce the cost of treatment and improve the level of exercise. Therefore, based on the results of this study, it can be said that the test which has been introduced could be used as an assessment tool for injury prevention. However, its relationship with other functional tests and some factors of physical fitness has not been studied