204 research outputs found
The structure and evolution of confined tori near a Hamiltonian Hopf Bifurcation
We study the orbital behavior at the neighborhood of complex unstable
periodic orbits in a 3D autonomous Hamiltonian system of galactic type. At a
transition of a family of periodic orbits from stability to complex instability
(also known as Hamiltonian Hopf Bifurcation) the four eigenvalues of the stable
periodic orbits move out of the unit circle. Then the periodic orbits become
complex unstable. In this paper we first integrate initial conditions close to
the ones of a complex unstable periodic orbit, which is close to the transition
point. Then, we plot the consequents of the corresponding orbit in a 4D surface
of section. To visualize this surface of section we use the method of color and
rotation [Patsis and Zachilas 1994]. We find that the consequents are contained
in 2D "confined tori". Then, we investigate the structure of the phase space in
the neighborhood of complex unstable periodic orbits, which are further away
from the transition point. In these cases we observe clouds of points in the 4D
surfaces of section. The transition between the two types of orbital behavior
is abrupt.Comment: 10 pages, 14 figures, accepted for publication in the International
Journal of Bifurcation and Chao
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A new combined approach using confocal and scanning electron microscopy to image surface modifications on quartzite
YesConfocal microscopy has been increasingly employed in the field of traceology to acquire metrological data of surface changes on a micro-scale. However, its advantages for a traditional visual inspection of use-wear are rarely highlighted.
As traditional optical microscopy (OM) has proven unable to entirely fulfil the prerequisites for an ideal observation of highly reflective and irregular materials, alternative ways for providing better observation conditions must be sought.
In this contribution, we explore the combination of laser scanning confocal (LSCM) and scanning electron microscopy (SEM) micro-graphs for the visual characterisation of wear on quartzite and evaluate the potential of both techniques.AHRC Fragmented Heritage project (AH/L00688X/1) at the University of Bradford, and of the MICINN-FEDER (PGC2018-093925-B-C32), the AGAUR (SGR 2017-1040) and the URV (2018PFR-URV-B2-91) projects at IPHES-URV. One of the authors (A.P.) was beneficiary of a Catalan pre-doctoral grant (2014FI B 00539), at the Rovira i Virgili University (URV), the IPHES and the Muséum national d’Histoire naturelle of Paris
Characterization of the use-wear and residues resulting from limestone working. Experimental approach to the parietal art of La Viña rock shelter (La Manzaneda, Asturias, Spain)
The Palaeolithic rock engravings that are located along the Nalón river basin in Northern Spain (central area of Asturias) have been studied from various perspectives (morphology, depth, style, manual range), but no use-wear studies on the stone tools used to produce such engravings have ever been undertaken. This paper aims to explore a new approach to this type of incisions based on use-wear analysis of experimental lithic tools used to engrave limestone blocks and slabs. Our results show that the use-wear traces generated by engraving limestone are well-developed and can be defined with specific criteria. The principal objective of this study was to provide the first experimental reference collection of use-wear resulting from engraving limestone using flint and quartzite experimental tools to compare with the traces that appear on tools in the archaeological record in contexts with parietal and portable art and, more specifically, to add a new approach to the multidisciplinary study of the La Viña rock shelter
Complex ecologies of trust in data practices and data-driven systems
Trust in data practices and data-driven systems is widely seen as both important and elusive. A data trust deficit has been identified, to which proposed solutions are often localised or individualised, focusing either on what institutions can do to increase user trust in their data practices or on data management models that empower the individual user. Scholarship on trust often focuses on typologies of trust. This paper shifts the emphasis to those doing the trusting, by presenting findings from empirical research which explored user perspectives on the data practices of the BBC. These findings challenge the assumption that localised or individualised solutions can be effective. They also suggest that conceptualisations of trust in data practices need to account for the complex range of factors which come into play in relation to trust in data and so move beyond the production of typologies. In this paper, we propose the concept of ‘complex ecologies of trust’ as a way of addressing all of these issues
Persistence of Asthmatic Response after Ammonium Persulfate-Induced Occupational Asthma in Mice
Since persulfate salts are an important cause of occupational asthma (OA), we aimed to study the persistence of respiratory symptoms after a single exposure to ammonium persulfate (AP) in AP-sensitized mice. BALB/c mice received dermal applications of AP or dimethylsulfoxide (DMSO) on days 1 and 8. On day 15, they received a single nasal instillation of AP or saline. Airway hyperresponsiveness (AHR) was assessed using methacholine provocation, while pulmonary inflammation was evaluated in bronchoalveolar lavage (BAL), and total serum immunoglobulin E (IgE), IgG1 and IgG2a were measured in blood at 1, 4, 8, 24 hours and 4, 8, 15 days after the single exposure to the causal agent. Histological studies of lungs were assessed. AP-treated mice showed a sustained increase in AHR, lasting up to 4 days after the challenge. There was a significant increase in the percentage of neutrophils 8 hours after the challenge, which persisted for 24 hours in AP-treated mice. The extent of airway inflammation was also seen in the histological analysis of the lungs from challenged mice. Slight increases in total serum IgE 4 days after the challenge were found, while IgG gradually increased further 4 to 15 days after the AP challenge in AP-sensitized mice. In AP-sensitized mice, an Ig-independent response is induced after AP challenge. AHR appears immediately, but airway neutrophil inflammation appears later. This response decreases in time; at early stages only respiratory and inflammatory responses decrease, but later on immunological response decreases as well
Persistence of respiratory and inflammatory responses after dermal sensitization to persulfate salts in a mouse model of non-atopic asthma
Exposure to ammonium persulfate (AP) has been reported to be the main cause of occupational asthma in hairdressers. The aim of this study is to assess how long the asthmatic response to AP can be induced after dermal sensitization in a mouse model. BALB/c mice received dermal applications of AP or dimethylsulfoxide (DMSO) (control) on days 1 and 8. They then received a single nasal instillation (challenge) of AP or saline on days 15, 22, 29, 36, 45, 60 and 90. Respiratory responsiveness to methacholine was measured 24 h after the challenge using a non-specific methacholine provocation test. Pulmonary inflammation was analysed in bronchoalveolar lavage (BAL), and total serum immunoglobulin (Ig) E, IgG1 and IgG2a were measured in serum samples. Histological analysis of lung slides was performed. Mice dermally sensitized and intranasally challenged with AP showed respiratory responsiveness to methacholine as long as 45 days after initial sensitization, as well as increased percentage of neutrophils in BAL compared with the control group. At day 60, dermally sensitized mice still presented bronchial hyperresponsiveness, while the percentage of neutrophils returned to baseline levels similar to those of controls. Total serum IgE increased significantly on day 22 after dermal sensitization. Total serum IgG1 and IgG2a increased from 45 days after dermal sensitization and remained high at 90 days. Both respiratory responsiveness to methacholine and airway inflammation responses decrease with increasing time between sensitization and challenge. Respiratory responsiveness to methacholine tends to persist longer than inflammation
Microbotanical residues for the study of early hominin tools
More than 2 million years ago in East Africa, the earliest hominin stone tools evolved amidst changes in resource base, with pounding technology playing a key role in this adaptive process. Olduvai Gorge (now Oldupai) is a famed locality that remains paramount for the study of human evolution, also yielding some of the oldest battering tools in the world. However, direct evidence of the resources processed with these technologies is lacking entirely. One way to obtain this evidence is through the analysis of surviving residues. Yet, linking residues with past processing activities is not simple. In the case of plant exploitation, this link can only be established by assessing site-based reference collections inclusive of both anthropogenic and natural residues as a necessary first step and comparative starting point. In this paper, we assess microbotanical remains from rock clasts sourced at the same quarry utilized by Oldowan hominins at Oldupai Gorge. We mapped this signal and analysed it quantitatively to classify its spatial distribution objectively, extracting proxies for taxonomic identification and further comparison with freestanding soils. In addition, we used blanks to manufacture pounding tools for blind, controlled replication of plant processing. We discovered that stone blanks are in fact environmental reservoirs in which plant remains are trapped by lithobionts, preserved as hardened accretions. Tool use, on the other hand, creates residue clusters; however, their spatial distribution can be discriminated from purely natural assemblages by the georeferencing of residues and statistical analysis of resulting patterns. To conclude, we provide a protocol for best practice and a workflow that has the advantage of overcoming environmental noise, reducing the risk of false positive, delivering a firm understanding of residues as polygenic mixtures, a reliable use of controls, and most importantly, a stronger link between microbotanical remains and stone tool use. © 2022. The Author(s).Materials and methods Results - Blanks as environmental reservoirs - Utilization creates residue clusters - Anthropogenic residue distribution - Of lichen habitability, proxy palimpsests, and hardened accretions - A protocol to study plant residue from Oldowan pounding tool
Falcarindiol purified from carrots leads to elevated levels of lipid droplets and upregulation of peroxisome proliferator-activated receptor-γ gene expression in cellular models
Recomanacions per al control de la brucel·losi a Catalunya
La brucel·losi humana es coneix al nostre país també amb els noms de febre de Malta i, en ocasions, de febre ondulant i de melitocòccia. Tanmateix, l'expressió brucel·losi ofereix nombrosos avantatges i hi ha una marcada tendència a incrementar-ne l'ús, per la qual cosa utilitzarem exclusivament aquesta denominació
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