Nuevas localidades con fauna ictiológica para el Neógeno menorquín

New places having ichthyological fauna are described in the Neogene of the island of Menorca (Balearic, Spain) and the Myliobatis sp. is shown to exist for the first time in the island All the referentes are summarized in the chart which is given

Nuevas localidades con fauna ictiológica para el Neógeno menorquín

Se citan nuevas localidades con fauna ictiológica en el Neógeno de la Isla de Menorca y se da a conocer el hallazgo de Myliobatis sp. por primera vez en la Isla. Al propio tiempo se sintetizan en un cuadro todas las referencias conocidas.New places having ichthyological fauna are described in the Neogene of the island of Menorca (Balearic, Spain) and the Myliobatis sp. is shown to exist for the first time in the island All the referentes are summarized in the chart which is given

Sobre la presencia de flysch en los sedimentos paleozoicos de la Isla de Menorca

En esta nota se señala por vez primera la presencia de turbiditas en la isla de Menorca. Son de edad paleozoica sin, en la actualidad, poderla aún precisar con exactitud. El trabajo debe considerarse como preliminar. Las turbiditas de los afloramientos de cala Tirant, de la carretera de Mahón a Fornells km 5,7 y km 20, del pueblo de Fornells y de la carretera de Mahón a Ciudadela km 19 y 23,7 son de facies de cuenca, y las turbiditas de cala Mesquida y de Els Freus son de facies de pendiente o marginales.In this paper it is shown, for the first time, the presence of turbidites in the Menorca Island (Baleares). They are of a Paleozoic age though its precise datation can not yet be known and this paper must be considered as a preliminary one. The turbidite outcrops of cala Tirant, those of the Mahón-Fornells road (km 5,7 and km 20), those of Fornells village and those encountered on the Mahón-Ciudadela road (km 19 and km 23,7) have a basin facies and the turbidites of cala Mesquida and of Els Freus have a marginal or slope one

Nueva aportación al conocimiento del Cuaternario menorquín

En esta nota, por una parte, se estudian unos materiales sedimentados bajo la acción del viento, que han suministrado abundante fauna, cuyo estudio permite conocer la posición estratigráfica de los mismos y, por la otra, se intenta establecer una síntesis general de los depósitos cuaternarios eólicos de la isla.Quaternary sediments from Menorca (Balearic Island) deposited by wind action contain a rich fauna o£ gasteropods

Biodegradation kinetics of dissolved organic matter chromatographic fractions

Controls on the degradation of dissolved organic matter (DOM) are complex but key to understand the role of freshwaters in the carbon cycle. Both the origin and previous degradation history have been suggested to determine DOM reactivity, but it is still a major challenge to understand the links between DOM composition and biodegradation kinetics. An appropriate context to study these links are intermittent rivers, as summer drought naturally diversifies DOM sources and sinks. Here we investigated the biodegradation kinetics of DOM in the main aquatic environments present in a temporary river. During dark incubations we traced the dynamics of bulk DOM and its main chromatographic fractions defined using LC-OCD: high molecular weight substances (HMWS), low molecular weight substances (LMWS), and humic substances and building blocks. Bulk DOM decay patterns were successfully fitted to the reactivity continuum (RC) biodegradation model. The RC parameters depicted running waters as the sites presenting a more reactive DOM, and temporary pools, enriched in leaf litter, as the ones with slowest DOM decay. The decay patterns of each DOM fraction were consistent throughout sites. LMWS and HMWS decayed in all cases and could be modeled using the RC model. Notably, the dynamics of LMWS controlled the bulk DOM kinetics. We discuss the mechanistic basis for the chromatographic fractions' kinetics during biodegradation and the implications that preconditioning and summer drought can have for DOM biodegradation in intermittent rivers

Motivar el aprendizaje utilizando nuevas tecnologías: Monitorización continua de glucosa

La innovación pretende: motivar, cambiar “el saber por saber hacer”, “fomentar el uso de nuevas tecnologías”, etc. Creemos que este proyecto abarca todo lo expuesto. La diabetes es la enfermedad endocrina más prevalente y la 7ª causa de muerte en el mundo. Los monitores continuos de glucosa son de gran ayuda para controlar la glucemia y reducir el riesgo de patología diabética. Hemos aprovechado esta idea para motivar a los estudiantes, e involucrarlos en esta propuesta de Flipped learning que nos ha llevado a elaborar un vídeo titulado “Monitorización continua de la glucemia”, en el que ellos mismos explican el funcionamiento y utilidad de este avance tecnológico. Con este proyecto hemos logrado: a) que constataran la importancia del páncreas en el control de la glucemia (al comparar los resultados obtenidos en estudiantes sanos con los de pacientes diabéticos); b) fomentar el uso de nuevas tecnologías; c) motivar y favorecer el aprendizaje autónomo y colaborativo; d) hacerlos protagonistas del vídeo y responsables de trasladar lo aprendido a sus compañeros; e) crear un material docente de calidad, útil para estudiantes, profesionales de Ciencias de la Salud y pacientes diabéticos (usuarios potenciales de estos dispositivos), disponible a través de las redes sociales

The drawdown phase of dam decommissioning is a hot moment of gaseous carbon emissions from a temperate reservoir

Dam decommissioning (DD) is a viable management option for thousands of ageing dams. Reservoirs are large carbon sinks, and reservoir drawdown results in important carbon dioxide (CO2) and methane (CH4) emissions. We studied the effects of DD on CO2 and CH4 fluxes from impounded water, exposed sediment, and lotic water before, during, and 3-10 months after drawdown of the Enobieta Reservoir, north Iberian Peninsula. During the study period, impounded water covered 0-100%, exposed sediment 0-96%, and lotic water 0-4% of the total reservoir area (0.14 km(2)). Areal CO2 fluxes in exposed sediment (mean [SE]: 295.65 [74.90] mmol m(-2) d(-1)) and lotic water (188.11 [86.09] mmol m(-2) d(-1)) decreased over time but remained higher than in impounded water (-36.65 [83.40] mmol m(-2) d(-1)). Areal CH4 fluxes did not change over time and were noteworthy only in impounded water (1.82 [1.11] mmol m(-2) d(-1)). Total ecosystem carbon (CO2 + CH4) fluxes (kg CO2-eq d(-1)) were higher during and after than before reservoir drawdown because of higher CO2 fluxes from exposed sediment. The reservoir was a net sink of carbon before reservoir drawdown and became an important emitter of carbon during the first 10 months after reservoir drawdown. Future studies should examine mid- and long-term effects of DD on carbon fluxes, identify the drivers of areal CO2 fluxes from exposed sediment, and incorporate DD in the carbon footprint of reservoirs.This study was funded by the projects Alteration of carbon sinks and sources in shrinking inland waters (Alter-C), the Spanish Ministry of Science, Innovation and Universities (refs: PID2020-114024GB-C31 funded by MCIN/AEI/10.13039/501100011033/) and Effects of the drawdown of Enobieta Reservoir (Navarre) on the biodiversity and functioning of river ecosystems (DESEMBALSE), Foundation BBVA (ref: PI064-17). AM was supported by an FI grant from the Agencia de Gestio d'Ajuts Universitaris i de Recerca (AGAUR) of the Generalitat de Catalunya. DvS and BO acknowledge support through the Consolidated Research Group 2017SGR0976. RM acknowledges support by the Generalitat de Catalunya through the Consolidated Research Group 2017SGR1124, and by the CERCA program. AE and MA support of the Basque Government through the Consolidated Research Group IT951-16. AM got a predoctoral grant by the University of the Basque Country (UPV/EHU). DvS is a Serra Hunter Fellow

Long-term clinical outcome of paraneoplastic cerebellar degeneration and anti-Yo antibodies

The outcome of 34 women with anti-Yo-associated paraneoplastic cerebellar degeneration was reviewed. Three patients had not developed cancer after more than 4 years of follow-up. The only independent predictor for survival was the type of associated tumor (risk ratio, 1.79; 95% CI, 1.02 to 3.12). Median survival was 100 months for patients with breast cancer and 22 for those with gynecologic cancer. Although paraneoplastic cerebellar degeneration leads to the diagnosis of cancer in 63% of the patients, cancer progression was the cause of death in 52%

Study design and baseline characteristics of patients on dialysis in the ASCEND-D trial

BACKGROUND: The Anemia Studies in chronic kidney disease (CKD): Erythropoiesis via a Novel prolyl hydroxylase inhibitor (PHI) Daprodustat-Dialysis (ASCEND-D) trial will test the hypothesis that daprodustat is non-inferior to comparator epoetin alfa or darbepoetin alfa for two co-primary endpoints: haemoglobin efficacy and cardiovascular safety. METHODS: We report the trial design, key demographic, clinical, and laboratory findings, and baseline therapies of 2964 patients randomised in the open-label (sponsor-blinded) active-controlled, parallel-group, randomised ASCEND-D clinical trial. We also compare baseline characteristics of ASCEND-D patients with patients who are on dialysis (CKD G5D) enrolled in other large cardiovascular outcome trials (CVOTs) and in the most relevant registries. RESULTS: The median age of patients was 58 years, 43% were female; 67% were white and 16% were black. The median haemoglobin at baseline was 10.4 g/dL. Among randomised patients, 89% were receiving haemodialysis and 11% peritoneal dialysis. Among key co-morbidities, 42% reported a history of diabetes mellitus, and 45% a history of cardiovascular disease. Median blood pressure was 134/74 mmHg. The median weekly dose of epoetin was 5751 units. Intravenous and oral iron use was noted in 64% and 11% of patients, respectively. Baseline demographics were similar to patients with CKD G5D enrolled in other CVOTs and renal patient registries. CONCLUSION: ASCEND-D will evaluate the efficacy and safety of daprodustat compared with epoetin alfa or darbepoetin alfa in the treatment of patients with anaemia with CKD G5D

Active collaboration with primary care providers increases specialist referral in chronic renal disease

BACKGROUND: Late referral to specialist nephrological care is associated with increased morbidity, mortality, and cost. Consequently, nephrologists' associations recommend early referral. The recommendations' effectiveness remains questionable: 22–51% of referrals need renal replacement therapy (RRT) within 3–4 months. This may be due to these recommendations addressing the specialist, rather than the primary care providers (PCP). The potential of specialist intervention aiming at slowing progression of chronic renal failure was introduced individually to some 250 local PCPs, and referral strategies were discussed. To overcome the PCPs' most often expressed fears, every referred patient was asked to report back to his PCP immediately after the initial specialist examination, and new medications were prescribed directly, and thus allotted to the nephrologist's budget. METHODS: In retrospective analysis, the stage of renal disease in patients referred within three months before the introductory round (group A, n = 18), was compared to referrals two years later (group B, n = 50). RESULTS: Relative number of patients remained stable (28%) for mild/ moderate chronic kidney disease (MMCKD), while there was a noticeable shift from patients referred severe chronic kidney disease (SCKD) (group A: 44%, group B: 20%) to patients referred in moderate chronic kidney disease (MCKD) (group A: 28%, group B: 52%). CONCLUSION: Individually addressing PCPs' ignorance and concerns noticeably decreased late referral. This stresses the importance of enhancing the PCPs' problem awareness and knowledge of available resources in order to ensure timely specialist referral