Measurement of the beam-helicity asymmetry in photoproduction of π0η pairs on carbon, aluminum, and lead

The beam-helicity asymmetry was measured, for the first time, in photoproduction of π0η pairs on carbon, aluminum, and lead, with the A2 experimental setup at MAMI. The results are compared to an earlier measurement on a free proton and to the corresponding theoretical calculations. The Mainz model is used to predict the beam-helicity asymmetry for the nuclear targets. The present results indicate that the photoproduction mechanism for π0η pairs on nuclei is similar to photoproduction on a free nucleon. This process is dominated by the D33 partial wave with the ηΔ(1232) intermediate state

First measurement of the polarization observable E and helicity-dependent cross sections in single π0 photoproduction from quasi-free nucleons

The double-polarization observable E and the helicity-dependent cross sections σ1/2 and σ3/2 have been measured for the first time for single π0 photoproduction from protons and neutrons bound in the deuteron at the electron accelerator facility MAMI in Mainz, Germany. The experiment used a circularly polarized photon beam and a longitudinally polarized deuterated butanol target. The reaction products, recoil nucleons and decay photons from the π0 meson were detected with the Crystal Ball and TAPS electromagnetic calorimeters. Effects from nuclear Fermi motion were removed by a kinematic reconstruction of the π0N final state. A comparison to data measured with a free proton target showed that the absolute scale of the cross sections is significantly modified by nuclear final-state interaction (FSI) effects. However, there is no significant effect on the asymmetry E since the σ1/2 and σ3/2 components appear to be influenced in a similar way. Thus, the best approximation of the two helicity-dependent cross sections for the free neutron is obtained by combining the asymmetry E measured with quasi-free neutrons and the unpolarized cross section corrected for FSI effects under the assumption that the FSI effects are similar for neutrons and protons

Measurement of the decay η′ →π0π0η at MAMI

An experimental study of the η′→π0π0η→6γ decay has been conducted with the best up-to-date statistical accuracy, by measuring η′ mesons produced in the γp→η′p reaction with the A2 tagged-photon facility at the Mainz Microtron, MAMI. The results obtained for the standard parametrization of the η′→π0π0η matrix element are consistent with the most recent results for η′→ππη decays, but have smaller uncertainties. The available statistics and experimental resolution allowed, for the first time, an observation of a structure below the π+π- mass threshold, the magnitude and sign of which, checked within the framework of the nonrelativistic effective-field theory, demonstrated good agreement with the cusp that was predicted based on the ππ scattering length combination, a0-a2, extracted from K→3π decays

First measurement using elliptically polarized photons of the double-polarization observable E for γp→pπ0 and γp→nπ+

We report the measurement of the helicity asymmetry E for the pπ0 and nπ+ final states using, for the first time, an elliptically polarized photon beam in combination with a longitudinally polarized target at the Crystal Ball experiment at MAMI. The results agree very well with data that were taken with a circularly polarized photon beam, showing that it is possible to simultaneously measure polarization observables that require linearly (e.g., G) and circularly polarized photons (e.g., E) and a longitudinally polarized target. The new data cover a photon energy range 270–1400 MeV for the pπ0 final state (230–842 MeV for the nπ+ final state) and the full range of pion polar angles, θ, providing the most precise measurement of the observable E. A moment analysis gives a clear observation of the pη cusp in the pπ0 final state

First measurement of helicity-dependent cross sections in π0η photoproduction from quasi-free nucleons

The helicity-dependent cross sections for the photoproduction of $\pi^0\eta$ pairs have been measured for the first time. The experiment was performed at the tagged photon facility of the Mainz MAMI accelerator with the combined Crystal Ball - TAPS calorimeter. The experiment used a polarized deuterated butanol target and a circularly polarized photon beam. This arrangement allowed the $\sigma_{1/2}$ (photon and target spin antiparallel) and $\sigma_{3/2}$ (parallel spins) components to be measured for quasi-free production of $\pi^0\eta$ pairs off protons and neutrons. The main finding is that the two helicity components contribute identically, within uncertainties, for both participant protons and neutrons. The absolute couplings for protons and neutrons are also identical. This means that nucleon resonances contributing to this reaction in the investigated energy range have almost equal electromagnetic helicity couplings, $A_{1/2}^{n,p}$ and $A_{3/2}^{n,p}$. Identical couplings for protons and neutrons are typical for $\Delta$ resonances and identical $A_{1/2}$ and $A_{3/2}$ components are only possible for $J\geq 3/2$ states, which constrains possible contributions of nucleon resonances.Comment: accepted for publication in Phys. Lett.

Threshold π⁰ photoproduction on transverse polarised protons at MAMI

Polarisation-dependent differential cross sections σTσT associated with the target asymmetry T have been measured for the reaction View the MathML sourceγp→→pπ0 with transverse target polarisation from π0π0 threshold to photon energies of 190 MeV. The data were obtained using a frozen-spin butanol target with the Crystal Ball / TAPS detector set-up and the Glasgow photon tagging system at the Mainz Microtron MAMI. Results for σTσT have been used in combination with our previous measurements of the unpolarised cross section σ0σ0 and the beam asymmetry Σ for a model-independent determination of S- and P -wave multipoles in the π0π0 threshold region, which includes for the first time a direct determination of the imaginary part of the E0+E0+ multipole

Decreased cytokine production by mononuclear cells after severe gram-negative infections: Early clinical signs and association with final outcome

Background: Failure of circulating monocytes for adequate cytokine production is a trait of sepsis-induced immunosuppression; however, its duration and association with final outcome are poorly understood. Methods: We conducted a substudy of a large randomised clinical trial. Peripheral blood mononuclear cells (PBMCs) were isolated within the first 24 h from the onset of systemic inflammatory response syndrome in 95 patients with microbiologically confirmed or clinically suspected gram-negative infections. Isolation was repeated on days 3, 7 and 10. PBMCs were stimulated for cytokine production. The study endpoints were the differences between survivors and non-survivors, the persistence of immunosuppression, and determination of admission clinical signs that can lead to early identification of the likelihood of immunosuppression. Results: PBMCs of survivors produced significantly greater concentrations of tumour necrosis factor-α (TNF-α), interleukin (IL)-6, IL-8, IL-10, interferon-γ and granulocyte-macrophage colony-stimulating factor after day 3. Using ROC analysis, we found that TNF-α production less than 250 pg/ml after lipopolysaccharide stimulation on day 3 could discriminate patients from healthy control subjects; this was associated with a 5.18 OR of having an unfavourable outcome (p = 0.046). This trait persisted as long as day 10. Logistic regression analysis showed that cardiovascular failure on admission was the only independent predictor of defective TNF-α production on day 3. Conclusions: Defective TNF-α production is a major trait of sepsis-induced immunosuppression. It is associated with significant risk for unfavourable outcome and persists until day 10. Cardiovascular failure on admission is predictive of defective TNF-α production during follow-up. Trial registration: ClinicalTrials.gov identifier: NCT01223690. Registered on 18 October 2010. © 2017 The Author(s)