1,081 research outputs found
Tracing planet-induced structures in circumstellar disks using molecular lines
Circumstellar disks are considered to be the birthplace of planets. Specific
structures like spiral arms, gaps, and cavities are characteristic indicators
of planet-disk interaction. Investigating these structures can provide insights
into the growth of protoplanets and the physical properties of the disk. We
investigate the feasibility of using molecular lines to trace planet-induced
structures in circumstellar disks. Based on 3D hydrodynamic simulations of
planet-disk interactions, we perform self-consistent temperature calculations
and produce N-LTE molecular line velocity-channel maps and spectra of these
disks using our new N-LTE line radiative transfer code Mol3D. Subsequently, we
simulate ALMA observations using the CASA simulator. We consider two nearly
face-on inclinations, 5 disk masses, 7 disk radii, and 2 different typical
pre-main-sequence host stars (T Tauri, Herbig Ae). We calculate up to 141
individual velocity-channel maps for five molecules/isotopoloques in a total of
32 rotational transitions to investigate the frequency dependence of the
structures indicated above. We find that the majority of protoplanetary disks
in our parameter space could be detected in the molecular lines considered.
However, unlike the continuum case, gap detection is not straightforward in
lines. For example, gaps are not seen in symmetric rings but are masked by the
pattern caused by the global (Keplerian) velocity field. We identify specific
regions in the velocity-channel maps that are characteristic of planet-induced
structures. Simulations of high angular resolution molecular line observations
demonstrate the potential of ALMA to provide complementary information about
the planet-disk interaction as compared to continuum observations. In
particular, the detection of planet-induced gaps is possible under certain
conditions.(abridged)Comment: 19 pages, 19 figures, accepted for publication in A&
The First Stars
We review recent theoretical results on the formation of the first stars in
the universe, and emphasize related open questions. In particular, we discuss
the initial conditions for Population III star formation, as given by variants
of the cold dark matter cosmology. Numerical simulations have investigated the
collapse and the fragmentation of metal-free gas, showing that the first stars
were predominantly very massive. The exact determination of the stellar masses,
and the precise form of the primordial initial mass function, is still hampered
by our limited understanding of the accretion physics and the protostellar
feedback effects. We address the importance of heavy elements in bringing about
the transition from an early star formation mode dominated by massive stars, to
the familiar mode dominated by low mass stars, at later times. We show how
complementary observations, both at high redshifts and in our local cosmic
neighborhood, can be utilized to probe the first epoch of star formation.Comment: 38 pages, 10 figures, draft version for 2004 Annual Reviews of
Astronomy and Astrophysics, high-resolution version available at
http://cfa-www.harvard.edu/~vbromm
Correlation length of hydrophobic polyelectrolyte solutions
The combination of two techniques (Small Angle X-ray Scattering and Atomic
Force Microscopy) has allowed us to measure in reciprocal and real space the
correlation length of salt-free aqueous solutions of highly charged
hydrophobic polyelectrolyte as a function of the polymer concentration ,
charge fraction and chain length . Contrary to the classical behaviour
of hydrophilic polyelectrolytes in the strong coupling limit, is strongly
dependent on . In particular a continuous transition has been observed from
to when decreased from 100% to
35%. We interpret this unusual behaviour as the consequence of the two features
characterising the hydrophobic polyelectrolytes: the pearl necklace
conformation of the chains and the anomalously strong reduction of the
effective charge fraction.Comment: 7 pages, 5 figures, submitted to Europhysics Letter
Treatment of cystoid macular edema with the new-generation NSAID nepafenac 0.1%
Seenu M Hariprasad1, Levent Akduman2, Joseph A Clever2, Michael Ober3,4, Franco M Recchia5, William F Mieler1,61Department of Ophthalmology and Visual Sciences, Vitreoretinal Service; 6Department of Ophthalmology and Visual Sciences, University of Chicago, Chicago, IL, USA; 2Vitreoretinal Service, Saint Louis University Eye Institute, Saint Louis, MO, USA; 3Vitreoretinal Service, Henry Ford Health Systems, West Bloomfield, MI, USA; 4Retinal Consultants of Michigan, Southfield, MI, USA; 5Vitreoretinal Service, Vanderbilt Eye Institute, Nashville, TN, USAPurpose: To describe the use of nepafenac 0.1% for cystoid macular edema (CME).Methods: This was a multicenter retrospective review of 22 CME cases (20 patients) treated with nepafenac 0.1% (six with concomitant prednisolone acetate 1%) from December 2005 to April 2008: three acute pseudophakic CME cases, 13 chronic/recalcitrant pseudophakic CME cases, and six cases of uveitic CME. Pre- and post-treatment retinal thickness and visual acuity were reported.Results: Following treatment for six weeks to six months, six eyes with uveitic CME showed a mean retinal thickness improvement of 227 ± 168.1 μm; mean best-corrected visual acuity (BCVA) improvement was 0.36 ± 0.20 logMAR. All three cases of acute pseudophakic CME improved after four to 10 weeks of nepafenac, with a mean improvement in retinal thickness of 134 ± 111.0 μm. BCVA improved in two patients (0.16 and 0.22 logMAR) but not in the third due to underlying retinal pigment epithelium changes. Thirteen eyes with chronic/recalcitrant pseudophakic CME demonstrated a mean improvement in retinal thickness of 178 ± 128.7 μm after nepafenac and mean BCVA improvement of 0.33 ± 0.19 logMAR.Conclusion: The positive outcomes of these 22 eyes strongly suggest that nepafenac 0.1% is a promising drug for the treatment of CME. Additional study under randomized controlled conditions is warranted.Keywords: macular edema, NSAID, nepafenac, cataract surgery, uveiti
Mechanism of Vanadium Leaching during Surface Weathering of Basic Oxygen Furnace Steel Slag Blocks: A Microfocus X-ray Absorption Spectroscopy and Electron Microscopy Study
© 2017 American Chemical Society. Basic oxygen furnace (BOF) steelmaking slag is enriched in potentially toxic V which may become mobilized in high pH leachate during weathering. BOF slag was weathered under aerated and air-excluded conditions for 6 months prior to SEM/EDS and μXANES analysis to determine V host phases and speciation in both primary and secondary phases. Leached blocks show development of an altered region in which free lime and dicalcium silicate phases were absent and Ca-Si-H was precipitated (CaCO 3 was also present under aerated conditions). μXANES analyses show that V was released to solution as V(V) during dicalcium silicate dissolution and some V was incorporated into neo-formed Ca-Si-H. Higher V concentrations were observed in leachate under aerated conditions than in the air-excluded leaching experiment. Aqueous V concentrations were controlled by Ca 3 (VO 4 ) 2 solubility, which demonstrate an inverse relationship between Ca and V concentrations. Under air-excluded conditions Ca concentrations were controlled by dicalcium silicate dissolution and Ca-Si-H precipitation, leading to relatively high Ca and correspondingly low V concentrations. Formation of CaCO 3 under aerated conditions provided a sink for aqueous Ca, allowing higher V concentrations limited by kinetic dissolution rates of dicalcium silicate. Thus, V release may be slowed by the precipitation of secondary phases in the altered region, improving the prospects for slag reuse
Binary separation in very thin nematic films: thickness and phase coexistence
The behavior as a function of temperature of very thin films (10 to 200 nm)
of pentylcyanobiphenyl (5CB) on silicon substrates is reported. In the vicinity
of the nematic/isotropic transition we observe a coexistence of two regions of
different thicknesses: thick regions are in the nematic state while thin ones
are in the isotropic state. Moreover, the transition temperature is shifted
downward following a 1/h^2 law (h is the film thickness). Microscope
observations and small angle X-ray scattering allowed us to draw a phase
diagram which is explained in terms of a binary first order phase transition
where thickness plays the role of an order parameter.Comment: 5 pages, 3 figures, submitted to PRL on the 26th of Apri
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Using Whole-Genome Sequence Data to Predict Quantitative Trait Phenotypes in Drosophila melanogaster
Predicting organismal phenotypes from genotype data is important for plant and animal breeding, medicine, and evolutionary biology. Genomic-based phenotype prediction has been applied for single-nucleotide polymorphism (SNP) genotyping platforms, but not using complete genome sequences. Here, we report genomic prediction for starvation stress resistance and startle response in Drosophila melanogaster, using ∼2.5 million SNPs determined by sequencing the Drosophila Genetic Reference Panel population of inbred lines. We constructed a genomic relationship matrix from the SNP data and used it in a genomic best linear unbiased prediction (GBLUP) model. We assessed predictive ability as the correlation between predicted genetic values and observed phenotypes by cross-validation, and found a predictive ability of 0.239±0.008 (0.230±0.012) for starvation resistance (startle response). The predictive ability of BayesB, a Bayesian method with internal SNP selection, was not greater than GBLUP. Selection of the 5% SNPs with either the highest absolute effect or variance explained did not improve predictive ability. Predictive ability decreased only when fewer than 150,000 SNPs were used to construct the genomic relationship matrix. We hypothesize that predictive power in this population stems from the SNP–based modeling of the subtle relationship structure caused by long-range linkage disequilibrium and not from population structure or SNPs in linkage disequilibrium with causal variants. We discuss the implications of these results for genomic prediction in other organisms
Discrete Variational Optimal Control
This paper develops numerical methods for optimal control of mechanical
systems in the Lagrangian setting. It extends the theory of discrete mechanics
to enable the solutions of optimal control problems through the discretization
of variational principles. The key point is to solve the optimal control
problem as a variational integrator of a specially constructed
higher-dimensional system. The developed framework applies to systems on
tangent bundles, Lie groups, underactuated and nonholonomic systems with
symmetries, and can approximate either smooth or discontinuous control inputs.
The resulting methods inherit the preservation properties of variational
integrators and result in numerically robust and easily implementable
algorithms. Several theoretical and a practical examples, e.g. the control of
an underwater vehicle, will illustrate the application of the proposed
approach.Comment: 30 pages, 6 figure
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