Inverse scattering approach to multiwavelength Fabry-Pérot laser design

A class of multiwavelength Fabry-Pérot lasers is introduced where the spectrum is tailored through a patterning of the cavity effective index. The cavity geometry is obtained using an inverse scattering approach and can be designed such that the spacing of discrete Fabry-Pérot lasing modes is limited only by the bandwidth of the inverted gain medium. A specific two-color semiconductor laser with a mode spacing in the THz region is designed, and measurements are presented demonstrating the simultaneous oscillation of the two wavelengths. The nonperiodic effective index profile of the particular two-color device considered is shown to be related to a Moiré or superstructure grating

Swift observations of the 2006 outburst of the recurrent nova RS Ophiuchi: III. X-ray spectral modelling

Following the Swift X-ray observations of the 2006 outburst of the recurrent nova RS Ophiuchi, we developed hydrodynamical models of mass ejection from which the forward shock velocities were used to estimate the ejecta mass and velocity. In order to further constrain our model parameters, here we present synthetic X-ray spectra from our hydrodynamical calculations which we compare to the Swift data. An extensive set of simulations was carried out to find a model which best fits the spectra up to 100 days after outburst. We find a good fit at high energies but require additional absorption to match the low energy emission. We estimate the ejecta mass to be in the range (2-5) x 10^{-7} solar masses and the ejection velocity to be greater than 6000 km/s (and probably closer to 10,000 km/s). We also find that estimates of shock velocity derived from gas temperatures via standard model fits to the X-ray spectra are much lower than the true shock velocities.Comment: 13 pages, 5 figures, Accepted for publication in Ap

What do we know about the nexus between culture, age, gender and health literacy? Implications for improving the health and well-being of young Indigenous males

Health literacy, although diversely defined, refers to the abilities, relationships and external environments required for people to successfully promote health. Existing research suggests that health literacy is related to health inequities, including individual and community capacity to navigate health. A diverse range of factors shape health literacy abilities and environments, especially culture, gender and age. However, the nexus between these variables and their cumulative impact on health literacy development remains largely unexplored. Commentary that explores these dynamics among young Indigenous males is particularly scant. In turn, strategies to bridge health equity gaps have been obscured. This article brings together disparate research on health literacy, masculinities, youth studies and men’s health in order to address this oversight. By outlining the collective conceptual contribution of these strands of scholarship, we show that young Indigenous males navigate health literacy through a complex cultural interface that balances both Western and Indigenous understandings of health. Alternative masculine identities, which simultaneously embrace and resist components of hegemonic masculinity, also shape this health literacy lens. We explain that the development of health literacy is important for young people, particularly young Indigenous males, and that this is negotiated in tandem with external support structures, including family and friends. By describing these intersections, we explore the implications for researchers, policymakers and practitioners seeking to achieve the dual goal of improving health literacy and reducing health inequi-ties among this highly marginalised population

Using social media in health literacy research: A promising example involving Facebook with young Aboriginal and Torres Strait Islander males from the top end of the Northern Territory

This brief report describes three key lessons learned during a health literacy research project with young Aboriginal and Torres Strait Islander males from the Top End of the Northern Territory (NT), Australia. More specifically, it is a methodologically focused paper that discusses processes associated with using a combination of yarning sessions and social media content as tools to unpack conceptualisations of health and well‐being among this marginalised population. The lessons discussed include (a) the utility of using social media in providing an authentic window into the lives of a hard‐to‐reach populations; (b) the need to carefully consider ethical implications; and (c) the benefits of using social media content to triangulate data and enhance methodological rigour. To understand the methodological contribution social media can make to equity‐focused health literacy research, it is first useful to understand what is meant by health literacy

Silicate dust in the environment of RS Ophiuchi following the 2006 eruption

We present further Spitzer Space Telescope observations of the recurrent nova RS Ophiuchi, obtained over the period 208-430 days after the 2006 eruption. The later Spitzer IRS data show that the line emission and free-free continuum emission reported earlier is declining, revealing incontrovertible evidence for the presence of silicate emission features at 9.7 and 18microns. We conclude that the silicate dust survives the hard radiation impulse and shock blast wave from the eruption. The existence of the extant dust may have significant implications for understanding the propagation of shocks through the red giant wind and likely wind geometry.Comment: 12 pages, 4 figures, accepted for publication in ApJ (Letters

Hepatocyte ABCA1 Deletion Impairs Liver Insulin Signaling and Lipogenesis

Plasma membrane (PM) free cholesterol (FC) is emerging as an important modulator of signal transduction. Here, we show that hepatocyte-specific knockout (HSKO) of the cellular FC exporter, ATPbinding cassette transporter A1 (ABCA1), leads to decreased PM FC content and defective trafficking of lysosomal FC to the PM. Compared with controls, chow-fed HSKO mice had reduced hepatic (1) insulin- stimulated Akt phosphorylation, (2) activation of the lipogenic transcription factor Sterol Regulatory Element Binding Protein (SREBP)-1c, and (3) lipogenic gene expression. Consequently, Westerntype diet-fed HSKO mice were protected from steatosis. Surprisingly, HSKO mice had intact glucose metabolism; they showed normal gluconeogenic gene suppression in response to re-feeding and normal glucose and insulin tolerance. We conclude that: (1) ABCA1 maintains optimal hepatocyte PM FC, through intracellular FC trafficking, for efficient insulin signaling; and (2) hepatocyte ABCA1 deletion produces a form of selective insulin resistance so that lipogenesis is suppressed but glucose metabolism remains normal

The iterated minimum modulus and conjectures of Baker and Eremenko

In transcendental dynamics significant progress has been made by studying points whose iterates escape to infinity at least as fast as iterates of the maximum modulus. Here we take the novel approach of studying points whose iterates escape at least as fast as iterates of the minimum modulus, and obtain new results related to Eremenko's conjecture and Baker's conjecture, and the rate of escape in Baker domains. To do this we prove a result of wider interest concerning the existence of points that escape to infinity under the iteration of a positive continuous function

Evaluation Research and Institutional Pressures: Challenges in Public-Nonprofit Contracting

This article examines the connection between program evaluation research and decision-making by public managers. Drawing on neo-institutional theory, a framework is presented for diagnosing the pressures and conditions that lead alternatively toward or away the rational use of evaluation research. Three cases of public-nonprofit contracting for the delivery of major programs are presented to clarify the way coercive, mimetic, and normative pressures interfere with a sound connection being made between research and implementation. The article concludes by considering how public managers can respond to the isomorphic pressures in their environment that make it hard to act on data relating to program performance.This publication is Hauser Center Working Paper No. 23. The Hauser Center Working Paper Series was launched during the summer of 2000. The Series enables the Hauser Center to share with a broad audience important works-in-progress written by Hauser Center scholars and researchers

A Multicellular Model of Intestinal Crypt Buckling and Fission

Crypt fission is an in vivo tissue deformation process that is involved in both intestinal homeostasis and colorectal tumourigenesis. Despite its importance, the mechanics underlying crypt fission are currently poorly understood. Recent experimental development of organoids, organ-like buds cultured from crypt stem cells in vitro, has shown promise in shedding light on crypt fission. Drawing inspiration from observations of organoid growth and fission in vivo, we develop a computational model of a deformable epithelial tissue layer. Results from in silico experiments show the stiffness of cells and the proportions of cell subpopulations affect the nature of deformation in the epithelial layer. In particular, we find that increasing the proportion of stiffer cells in the layer increases the likelihood of crypt fission occurring. This is in agreement with and helps explain recent experimental work