30-Day morbidity and mortality of bariatric metabolic surgery in adolescence during the COVID-19 pandemic – The GENEVA study

Background: Metabolic and bariatric surgery (MBS) is an effective treatment for adolescents with severe obesity. Objectives: This study examined the safety of MBS in adolescents during the coronavirus disease 2019 (COVID-19) pandemic. Methods: This was a global, multicentre and observational cohort study of MBS performed between May 01, 2020, and October 10,2020, in 68 centres from 24 countries. Data collection included in-hospital and 30-day COVID-19 and surgery-specific morbidity/mortality. Results: One hundred and seventy adolescent patients (mean age: 17.75 ± 1.30 years), mostly females (n = 122, 71.8%), underwent MBS during the study period. The mean pre-operative weight and body mass index were 122.16 ± 15.92 kg and 43.7 ± 7.11 kg/m2, respectively. Although majority of patients had pre-operative testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (n = 146; 85.9%), only 42.4% (n = 72) of the patients were asked to self-isolate pre-operatively. Two patients developed symptomatic SARS-CoV-2 infection post-operatively (1.2%). The overall complication rate was 5.3% (n = 9). There was no mortality in this cohort. Conclusions: MBS in adolescents with obesity is safe during the COVID-19 pandemic when performed within the context of local precautionary procedures (such as pre-operative testing). The 30-day morbidity rates were similar to those reported pre-pandemic. These data will help facilitate the safe re-introduction of MBS services for this group of patients

30-day morbidity and mortality of sleeve gastrectomy, Roux-en-Y gastric bypass and one anastomosis gastric bypass: a propensity score-matched analysis of the GENEVA data

Background: There is a paucity of data comparing 30-day morbidity and mortality of sleeve gastrectomy (SG), Roux-en-Y gastric bypass (RYGB), and one anastomosis gastric bypass (OAGB). This study aimed to compare the 30-day safety of SG, RYGB, and OAGB in propensity score-matched cohorts. Materials and methods: This analysis utilised data collected from the GENEVA study which was a multicentre observational cohort study of bariatric and metabolic surgery (BMS) in 185 centres across 42 countries between 01/05/2022 and 31/10/2020 during the Coronavirus Disease-2019 (COVID-19) pandemic. 30-day complications were categorised according to the Clavien–Dindo classification. Patients receiving SG, RYGB, or OAGB were propensity-matched according to baseline characteristics and 30-day complications were compared between groups. Results: In total, 6770 patients (SG 3983; OAGB 702; RYGB 2085) were included in this analysis. Prior to matching, RYGB was associated with highest 30-day complication rate (SG 5.8%; OAGB 7.5%; RYGB 8.0% (p = 0.006)). On multivariate regression modelling, Insulin-dependent type 2 diabetes mellitus and hypercholesterolaemia were associated with increased 30-day complications. Being a non-smoker was associated with reduced complication rates. When compared to SG as a reference category, RYGB, but not OAGB, was associated with an increased rate of 30-day complications. A total of 702 pairs of SG and OAGB were propensity score-matched. The complication rate in the SG group was 7.3% (n = 51) as compared to 7.5% (n = 53) in the OAGB group (p = 0.68). Similarly, 2085 pairs of SG and RYGB were propensity score-matched. The complication rate in the SG group was 6.1% (n = 127) as compared to 7.9% (n = 166) in the RYGB group (p = 0.09). And, 702 pairs of OAGB and RYGB were matched. The complication rate in both groups was the same at 7.5 % (n = 53; p = 0.07). Conclusions: This global study found no significant difference in the 30-day morbidity and mortality of SG, RYGB, and OAGB in propensity score-matched cohorts

Reconciling the stratigraphy and depositional history of the Lycian orogen-top basins, SW Anatolia

Terrestrial fossil records from the SWAnatolian basins are crucial both for regional correlations and palaeoenvironmental reconstructions. By reassessing biostratigraphic constraints and incorporating new fossil data, we calibrated and reconstructed the late Neogene andQuaternary palaeoenvironments within a regional palaeogeographical framework. The culmination of the Taurides inSWAnatolia was followed by a regional crustal extension from the late Tortonian onwards that created a broad array of NE-trending orogen-top basins with synchronic associations of alluvial fan, fluvial and lacustrine deposits. The terrestrial basins are superimposed on the upper Burdigalian marine units with a c. 7 myr of hiatus that corresponds to a shift from regional shortening to extension. The initial infill of these basins is documented by a transition from marginal alluvial fans and axial fluvial systems into central shallow-perennial lakes coinciding with a climatic shift from warm/humid to arid conditions. The basal alluvial fan deposits abound in fossil macro-mammals of an early Turolian (MN11–12; late Tortonian) age. The Pliocene epoch in the region was punctuated by subhumid/humid conditions resulting in a rise of local base levels and expansion of lakes as evidenced by marsh-swamp deposits containing diverse fossilmammal assemblages indicating late Ruscinian (lateMN15; late Zanclean) ageWe are grateful for the support of the international bilateral project between The Scientific and Technological Research Council of Turkey (TUBITAK) and The Russian Scientific Foundation (RFBR) with grant a number of 111Y192. M.C.A. is grateful to the Turkish Academy of Sciences (TUBA) for a GEBIP (Young Scientist Award) grant. T.K. and S.M. are grateful to the Ege University Scientific Research Center for the TTM/002/2016 and TTM/001/2016 projects. M.C.A., H.A., S.M. and M.B. have obtained Martin and Temmick Fellowships at Naturalis Biodiversity Center (Leiden). F.A.D. is supported by a Mehmet Akif Ersoy University Scientific Research Grant. T.A.N. is supported by an Alexander-von-Humboldt Scholarship. L.H.O. received support from TUBITAK under the 2221 program for visiting scientists

ASSESSMENT OF RPIM SHAPE PARAMETERS FOR SOLUTION ACCURACY OF 2D GEOMETRICALLY NONLINEAR PROBLEMS

This study discussed the effects of shape parameters on the radial point interpolation method (RPIM) accuracy in 2D geometrically nonlinear problems. Four finite deformation problems with compressible Neo-Hookean material are numerically solved with the RPIM algorithm using the multi-quadric (MQ) radial basis function. Both regular and irregular node distributions are used. Their displacements and Cauchy stresses are compared for different values of shape parameters and monomial basis. It is found that the shape parameters proposed for linearly elastic problems (q = 1.03, alpha(c) = 4) can still be applicable to 2D geometrically nonlinear problems but careful selections should be made for the calculation of stress. For example, when q is used as 1.75 with irregular node distributions, stresses can be calculated more precisely

Zero-valent iron nanoparticles containing nanofiber scaffolds for nerve tissue engineering

PMID = 3301010

URF (Survey Of Risk Factor Management) Çalışması Türkiye Değerlendirmesi: Türkiyeden Farklı Basamaklardan 15 Sağlık Merkezinin Verilerinde Kardiyovasküler Risk Faktörleri Kontrol Oranları

Scopu

Call Admission Control Jointly with Resource Reservation in Cellular Wireless Networks

To efficiently utilize the total resources and to serve mobile users demanding for different types of service, system resource utilization of these services should be considered, and efficient resource management techniques should be developed. In this paper, we propose a new call admission control (CAC) scheme jointly with resource management by considering the two service types: prioritized calls and nonprioritized calls. Proposed scheme limits the new and handoff prioritized and non-prioritized call arrivals according to call-level quality of service (QoS) requirements. By searching algorithm, admission parameters are obtained optimally and required QoS are guaranteed. Due to high priority of the prioritized calls, the admittance of non-prioritized calls into channel is restricted, while prioritized calls are admitted as long as there is sufficient bandwidth. To evaluate the performance of the proposed CAC scheme, we have compared the numerical results from the analytical model with those of New Call Bounding scheme. It is shown that the proposed CAC scheme uses the resources effectively and improves all the upper-bound QoS requirements with respect to the New Call Bounding scheme for prioritized and non-prioritized users

Work Ethic, religion and moral energy: The case of Turkish SME owner-managers

This paper explores the hitherto neglected issue of how religious beliefs influence the work ethic of Turkish SME (Small and Medium-sized Enterprise) owner-managers. We draw on Weber’s notion of Lebensführung, which captures the manner of living one’s life, as a theoretical and explanatory lens. The research is conducted among religious Muslim entrepreneurs, which showed strong diaspora characteristics in its early emergence in 1990s. Based on qualitative research on Turkish entrepreneurs (SME owner-managers), we find that a new Islamic discourse –appearing as more liberal and pro market oriented- together with the Muslim work ethic, drive entrepreneurialism in Turkey. We demonstrate that the contemporary Muslim work ethic comprises a ‘moral energy’, which manifests itself variously as rational/secular, shared/communicated, and action-oriented driver for Muslim entrepreneurs, helping to sustain their entrepreneurial activities in the Turkish context