The role of RIG-I, AIM2 and IFI16 receptors for viral RNA and DNA in the pathogenesis of spontaneous and early missed miscarriage

Aim: to identify the features of the expression of mRNA of intracellular RIG-I, IFI16 and AIM2 receptors for viral RNA and DNA, and their signaling pathway proteins in the decidual tissue of patients with spontaneous and early missed miscarriage

Milk Urea Content and δ13C as Potential Tool for Differentiation of Milk from Organic and Conventional Low- and High-Input Farming Systems

The influence of farming type (conventional or organic) and production system (low-and high-input) on various quality characteristics of milk have been in the focus of studies over the last decade. The aim of this work was to evaluate the impact of different dairy management and production systems on carbon stable isotopes ratio (δ13C) and milk urea content. The samples of raw milk were collected each two weeks at certified organic high-input and low-input farms, conventional high-input and low-input farms in late indoor period and outdoor period. Data analysis showed clear difference between milk from organic high- and low-input farms with non-overlapping range between -22.90 ‰ and -24.70‰ for δ13С in protein fraction (equal 1.80‰) and between -25.90‰ and -28.20‰ (equal 2.30‰) for δ13С in fat fraction independently from season factor, as for Δδ13С (protein-fat) values in milk from high-input (1.50-3.00‰) and low-input (3.20-6.30‰) organic farms. Analysis of correlation between δ13С in protein fraction and milk urea content values showed that during late indoor period the most significant difference was detected between milk from organic low-input and conventional high-input farms (5.85‰ for δ13С in protein fraction and 4.65 mg/100 g of milk urea content). During outdoor period, the non-overlapping range was established for low-input and high-input organic farms (3.40‰ for δ13С in protein fraction and 10.77 mg/100 g of milk urea content). Results of δ13С values in fat and protein milk fractions, as combination of δ13С in protein fraction and milk urea content could be a potential tool for the distinguish of milk from different farming types, based on different feed composition

Organization of distance education in the subject “Аnimal physiology” with using the electronic learning platform MOODLE and YouTube video hosting

The current development level in IT contributes to the introduction of computer technology and other technologies in the learning process at various levels of education. Informatization of education is a process that provides the education sector with methodology and practice for the development and optimal use of modern information and communication technologies focused on implementing the psychological and pedagogical goals of education and training. Education institutions face the challenge of preparing a new generation of teachers to use the new learning tools in teaching practices effectively. Information technologies allow the university teacher to prepare and conduct practical classes and lectures and control activities effectively and at a new level. This article highlights the experience of organizing the educational process in a distance format using information computer technologies. It analyzes the work of the most common online distance learning platforms, with the help of which the educational process takes place at the State University of Biotechnology. The authors investigated the possibilities of the electronic learning platform MOODLE (Modular Object-Oriented Dynamic Learning Environment) for students of the Veterinary medicine and biotechnology faculties. An analysis of the advantages of the MOODLE distance learning platform and ways to eliminate its shortcomings was carried out, the main of which, according to the authors, is the need to adapt the teaching of one of the essential fundamental disciplines to the video format and provide the combination of visualization of the classroom performance of laboratory and practical work with the possibility of independent, remote work if available access to the Internet. It is claimed that the MOODLE platform can use a wide range of video files, but this is not enough for a perfect study of the discipline “Animal Physiology”. Due to the limitation of specific technical characteristics of the MOODLE platform, the authors introduced files from YouTube video hosting into the educational process, which required creating their content. In the article, the authors presented their views on the creation of a single virtual, informational environment that combines all available technological functions of the system of professional training of future doctors of veterinary medicine

Formation of groundwater levels of drained lands in the natural and climatic conditions of the Novgorod region

Studies on the formation of groundwater levels have been carried out on open and closed drainage systems in the natural and climatic conditions of the Novgorod region for more than 30 years at 2 pilot production sites. On the first site there are 4 structures of closed drainage: shallow with a depth of 70 cm; medium-deep drainage (drainage depth 110 cm) with various options for filling the drainage trench-wood chips and sand-gravel mixture; two-tier drainage (drainage depth 110 and 60 cm). On the second site there are four open drainage structures: channels; hollows – without hydro-reclamation structures; with drainage along the bottom-tubular and strip-free. The average long-term data on groundwater regimes on experimental structures were obtained and conclusions were drawn that the average seasonal groundwater level formed by closed drainage systems is 18 cm lower compared to open drainage systems; the most favorable groundwater regime is formed by drainage systems of two-tier drainage. The dependences of groundwater levels formed during the most intense periods of operation of drainage systems (May – 1st decade of June) on the amount of precipitation for previous periods are analyzed. It was revealed that the closeness of the relationship between groundwater levels and the amount of precipitation in the open drainage variants is less close (r2 = 0.01-0.30) compared with the closed drainage variants (r2 = 0.02-0.54). The closest relationship on closed drainage systems is observed between the groundwater level of the third decade of May and precipitation for May: during this period, with an increase in precipitation by 1 mm, groundwater rises by 0.3 cm – in the variant with chip filling and by 0.6 cm – in the variants of shallow and two-tier drainage

Обоснование весовых норм для тяжеловесного движения

For the English full text of the article please see the attached PDF-File (English version follows Russian version).ABSTRACT The article substantiates the weight standards for heavy trains, evaluates the technology of their formation, taking into account the existing factors and conditions. In particular, it is taken into account that in heavy traffic, locomotives with a large number of sections are used, the speed and travel time for all cargo trains should be the same, and the weight standards should be chosen so as to ensure the minimum cost of mastering the specified traffic volumes. The promising importance of heavy weight trains requires development of technologically substantiated weight standards for those trains, so that those standards should comply with harmonized standards for ordinary trains. So the article offers description of main factors that should be taken into consideration while substantiating weight standards for heavy trains. The authors quote examples of possible variants of weight standards, methods of calculation of mean weights, structure of freight costs for different weight standards for both ordinary and heavy trains. Keywords: railway, heavy trains, weight norms, linear loads, weight standard, distribution of actual train weights, distribution of trains’ lengths.Полный текст на англ. языке находится в прилагаемом файле ПДФ (англ. версия следует после русской версии).В статье обосновываются весовые нормы для тяжеловесных поездов, оценивается технология их формирования с учётом существующих факторов и условий. В частности, во внимание принимается, что в тяжеловесном движении используются локомотивы с большим числом секций, скорость и время хода по перегонам всех грузовых поездов должны быть одинаковы, а весовые нормы выбираться так, чтобы обеспечивать минимум затрат на освоение заданных объёмов перевозок. Значимость и перспективность формирования тяжеловесных поездов требует разработки технологически обоснованных весовых норм с увязкой, согласованием их с унифицированными нормами для обычных поездов. Приводятся примеры возможных вариантов весовых норм, методика расчёта средних весов, структура грузовых перевозочных затрат при оценке норм для тяжеловесных и обычных поездов

Качество жизни при цервикальной дистонии

The aim of the study was to study the physical and psychological components regarding the quality of life of patients with cervical dystonia.Material and methods. 170 respondents were examined. The main group included 120 patients with cervical dystonia, 50 patients were included in the control group, consisting of patients with cervicalgia of various genesis. The diagnosis of cervical dystonia met uniform criteria for the diagnosis and treatment of dystonia adopted in 2011 by the European Federation of Neurological Societies and the Movement Disorders Society (European Federation of Neurological Societies / Movement Disorders Society, EFNS / MDS). In the control group, the pain syndrome of the cervical spine was caused by a degenerative process and was confirmed by X-ray examination and /or MRI. As part of our research, we determined the quality of life in men and women in both groups using the SF-36 questionnaire with a study of the parameters of physical and psychological well-being.Results and conclusion. A considerably significant effect of cervical dystonia on the somatic and mental  parameters regarding the quality of life in both men and women has been established. Significant decrease in all indicators representing the quality of life in patients with cervical dystonia was revealed compared with respondents without dystonic hyperkinesis. As a chronic disease, cervical dystonia leads to psycho-physiological stress, which significantly impairs the quality of life of patients. Significant gender differences were identified: women from the groups of cervical dystonia and cervicalgia were more often exposed to psychological deprivation and reduced physical activity than men from the same groups.Цель. Изучить физические и психологические составляющие качества жизни больных, страдающих цервикальной дистонией.Материалы и методы. Обследованы 170 респондентов: 120 пациентов с цервикальной дистонией составили основную группу, 50 человек включены в группу контроля – респонденты с цервикалгиями различного генеза. Диагноз цервикальной дистонии установлен клинически, согласно единым критериям по диагностике и лечению дистонии, принятым в 2011 г. Европейской федерацией неврологических обществ и Обществом двигательных расстройств (European Federation of Neurological Societies / Movement Disorders Society, EFNS / MDS). Болевой синдром в шейном отделе позвоночника у группы контроля был вызван дегенеративным процессом и подтвержден рентгенографическим обследованием и (или) магнитно-резонансной томографией. В рамках проводимого нами исследования определялось качество жизни у мужчин и женщин в обеих группах с помощью опросника SF-36 с изучением параметров физического и психологического благополучия.Результаты и заключение. Установлено достоверно значимое влияние цервикальной дистонии на соматические и психические параметры качества жизни как у мужчин, так и у женщин. Выявлено достоверное снижение всех показателей качества жизни у больных цервикальной дистонией по сравнению с респондентами, не имеющих дистонического гиперкинеза. Цервикальная дистония как хроническое заболевание приводит к психофизиологическому напряжению, что значительно ухудшает качество жизни больных. Выявлены достоверные гендерные внутригрупповые различия: женщины из групп цервикальной дистонии и цервикалгий в большей степени подвержены психологической депривации и снижению физической деятельности, чем мужчины из этих же групп

Tree canopy affects soil macrofauna spatial patterns on broad- and meso- scale levels in an Eastern European poplar-willow forest in the floodplain of the River Dnipro

This paper tested the hypothesis that the placement of trees in the floodplain ecosystem leads to multiscale spatial structuring and plays an important role in formation of the spatial patterns of the soil macrofauna. The research polygon was laid in an Eastern European poplar-willow forest in the floodplain of the River Dnipro. The litter macrofauna was manually collected from the soil samples. The distances of the sampling locations from the nearest individual of each tree species were applied to obtain a measure of the overstorey spatial structure. The pure effect of tree structured space on the soil animal community was presented by the broad-scale and meso-scale components. The soil animal community demonstrated patterns varying in tree structured space. The tree induced spatial heterogeneity was revealed to effect on the vertical stratification of the soil animal community. The complex nature of the soil animal community variability depending on the distance from trees was depended on the interaction of tree species in their effects on soil animals. The importance of the spatial structures that interact with soil, plants and tree factors in shaping soil macrofauna communities was shown