4,361 research outputs found
Letter from Geo. O. Turk
Letter concerning an outline of a proposed home study course in agriculture
Replicated partitioning for undirected hypergraphs
Cataloged from PDF version of article.Hypergraph partitioning (HP) and replication are diverse but powerful tools that are traditionally applied separately to minimize the costs of parallel and sequential systems that access related data or process related tasks. When combined together, these two techniques have the potential of achieving significant improvements in performance of many applications. In this study, we provide an approach involving a tool that simultaneously performs replication and partitioning of the vertices of an undirected hypergraph whose vertices represent data and nets represent task dependencies among these data. In this approach, we propose an iterative-improvement-based replicated bipartitioning heuristic, which is capable of move, replication, and unreplication of vertices. In order to utilize our replicated bipartitioning heuristic in a recursive bipartitioning framework, we also propose appropriate cut-net removal, cut-net splitting, and pin selection algorithms to correctly encapsulate the two most commonly used cutsize metrics. We embed our replicated bipartitioning scheme into the state-of-the-art multilevel HP tool PaToH to provide an effective and efficient replicated HP tool, rpPaToH. The performance of the techniques proposed and the tools developed is tested over the undirected hypergraphs that model the communication costs of parallel query processing in information retrieval systems. Our experimental analysis indicates that the proposed technique provides significant improvements in the quality of the partitions, especially under low replication ratios. (C) 2012 Elsevier Inc. All rights reserved
Optimized Multi-Frequency Spectra for Applications in Radiative Feedback and Cosmological Reionization
The recent implementation of radiative transfer algorithms in numerous
hydrodynamics codes has led to a dramatic improvement in studies of feedback in
various astrophysical environments. However, because of methodological
limitations and computational expense, the spectra of radiation sources are
generally sampled at only a few evenly-spaced discrete emission frequencies.
Using one-dimensional radiative transfer calculations, we investigate the
discrepancies in gas properties surrounding model stars and accreting black
holes that arise solely due to spectral discretization. We find that even in
the idealized case of a static and uniform density field, commonly used
discretization schemes induce errors in the neutral fraction and temperature by
factors of two to three on average, and by over an order of magnitude in
certain column density regimes. The consequences are most severe for radiative
feedback operating on large scales, dense clumps of gas, and media consisting
of multiple chemical species. We have developed a method for optimally
constructing discrete spectra, and show that for two test cases of interest,
carefully chosen four-bin spectra can eliminate errors associated with
frequency resolution to high precision. Applying these findings to a fully
three-dimensional radiation-hydrodynamic simulation of the early universe, we
find that the HII region around a primordial star is substantially altered in
both size and morphology, corroborating the one-dimensional prediction that
discrete spectral energy distributions can lead to sizable inaccuracies in the
physical properties of a medium, and as a result, the subsequent evolution and
observable signatures of objects embedded within it.Comment: 15 pages, 13 figures, 2 tables, accepted for publication in the
Astrophysical Journa
Open questions in the study of population III star formation
The first stars were key drivers of early cosmic evolution. We review the
main physical elements of the current consensus view, positing that the first
stars were predominantly very massive. We continue with a discussion of
important open questions that confront the standard model. Among them are
uncertainties in the atomic and molecular physics of the hydrogen and helium
gas, the multiplicity of stars that form in minihalos, and the possible
existence of two separate modes of metal-free star formation.Comment: 15 pages, 2 figures. To appear in the conference proceedings for IAU
Symposium 255: Low-Metallicity Star Formation: From the First Stars to Dwarf
Galaxie
Turbulence Time Series Data Hole Filling using Karhunen-Loeve and ARIMA methods
Measurements of optical turbulence time series data using unattended
instruments over long time intervals inevitably lead to data drop-outs or
degraded signals. We present a comparison of methods using both Principal
Component Analysis, which is also known as the Karhunen--Loeve decomposition,
and ARIMA that seek to correct for these event-induced and mechanically-induced
signal drop-outs and degradations. We report on the quality of the correction
by examining the Intrinsic Mode Functions generated by Empirical Mode
Decomposition. The data studied are optical turbulence parameter time series
from a commercial long path length optical anemometer/scintillometer, measured
over several hundred metres in outdoor environments.Comment: 8 pages, 9 figures, submitted to ICOLAD 2007, City University,
London, U
Mice with genetic deletion of group VIA phospholipase A2β exhibit impaired macrophage function and increased parasite load in Trypanosoma cruzi-induced myocarditis
Trypanosoma cruzi infection, which is the etiological agent of Chagas disease, is associated with intense inflammation during the acute and chronic phases. The pathological progression of Chagas disease is influenced by the infiltration and transmigration of inflammatory cells across the endothelium to infected tissues, which are carefully regulated processes involving several molecular mediators, including adhesion molecules and platelet-activating factor (PAF). We have shown that PAF production is dependent upon calcium-independent group VIA phospholipase A(2)β (iPLA(2)β) following infection of human coronary artery endothelial cells (HCAECs) with T. cruzi, suggesting that the absence of iPLA(2)β may decrease the recruitment of inflammatory cells to the heart to manage parasite accumulation. Cardiac endothelial cells isolated from iPLA(2)β-knockout (iPLA(2)β-KO) mice infected with T. cruzi demonstrated decreased PAF production compared to that by cells isolated from wild-type (WT) mice but demonstrated increases in adhesion molecule expression similar to those seen in WT mice. Myocardial inflammation in iPLA(2)β-KO mice infected with T. cruzi was similar in severity to that in WT mice, but the iPLA(2)β-KO mouse myocardium contained more parasite pseudocysts. Upon activation, macrophages from iPLA(2)β-KO mice produced significantly less nitric oxide (NO) and caused less T. cruzi inhibition than macrophages from wild-type mice. Thus, the absence of iPLA(2)β activity does not influence myocardial inflammation, but iPLA(2)β is essential for T. cruzi clearance
Anticancer activity of crumpled aluminum nanosheets through disruption of ion balance in tumor microenvironment
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