1,292 research outputs found
Citizens' attitudes to contact tracing apps
Citizens’ concerns about data privacy and data security breaches may reduce the adoption of COVID-19 contact tracing mobile phone applications, making them less effective. We implement a choice experiment (conjoint experiment) where participants indicate which version of two contact tracing apps they would install, varying the apps’ privacy-preserving attributes. Citizens do not always prioritise privacy and prefer a centralised National Health Service system over a decentralised system. In a further study asking about participants’ preference for digital-only vs human-only contact tracing, we find a mixture of digital and human contact tracing is supported. We randomly allocated a subset of participants in each study to receive a stimulus priming data breach as a concern, before asking about contact tracing. The salient threat of unauthorised access or data theft does not significantly alter preferences in either study. We suggest COVID-19 and trust in a national public health service system mitigate respondents’ concerns about privacy
Hadron calorimeter with MAPD readout in the NA61/SHINE experiment
The modular hadron calorimeter with micro-pixel avalanche photodiodes readout
for the NA61/SHINE experiment at the CERN SPS is presented. The calorimeter
consists of 44 independent modules with lead-scintillator sandwich structure.
The light from the scintillator tiles is captured by and transported with
WLS-fibers embedded in scintillator grooves. The construction provides a
longitudinal segmentation of the module in 10 sections with independent MAPD
readout. MAPDs with pixel density of /mm ensure good linearity of
calorimeter response in a wide dynamical range. The performance of the
calorimeter prototype in a beam test is reported
Detecting the Companions and Ellipsoidal Variations of RS CVn Primaries: II. omicron Draconis, a Candidate for Recent Low-Mass Companion Ingestion
To measure the stellar and orbital properties of the metal-poor RS CVn binary
o Draconis (o Dra), we directly detect the companion using interferometric
observations obtained with the Michigan InfraRed Combiner at Georgia State
University's Center for High Angular Resolution Astronomy (CHARA) Array. The
H-band flux ratio between the primary and secondary stars is the highest
confirmed flux ratio (370 +/- 40) observed with long-baseline optical
interferometry. These detections are combined with radial velocity data of both
the primary and secondary stars, including new data obtained with the
Tillinghast Reflector Echelle Spectrograph on the Tillinghast Reflector at the
Fred Lawrence Whipple Observatory and the 2-m Tennessee State University
Automated Spectroscopic Telescope at Fairborn Observatory. We determine an
orbit from which we find model-independent masses and ages of the components
(M_A = 1.35 +\- 0.05 M_Sun, M_B = 0.99 +\- 0.02 M_Sun, system age = 3.0 -\+ 0.5
Gyr). An average of a 23-year light curve of o Dra from the Tennessee State
University Automated Photometric Telescope folded over the orbital period newly
reveals eclipses and the quasi-sinusoidal signature of ellipsoidal variations.
The modeled light curve for our system's stellar and orbital parameters confirm
these ellipsoidal variations due to the primary star partially filling its
Roche lobe potential, suggesting most of the photometric variations are not due
to stellar activity (starspots). Measuring gravity darkening from the average
light curve gives a best-fit of beta = 0.07 +\- 0.03, a value consistent with
conventional theory for convective envelope stars. The primary star also
exhibits an anomalously short rotation period, which, when taken with other
system parameters, suggests the star likely engulfed a low-mass companion that
had recently spun-up the star.Comment: 14 pages, 13 figures, Accepted to Ap
Detecting the Companions and Ellipsoidal Variations of RS CVn Primaries: I. sigma Geminorum
To measure the properties of both components of the RS CVn binary sigma
Geminorum (sigma Gem), we directly detect the faint companion, measure the
orbit, obtain model-independent masses and evolutionary histories, detect
ellipsoidal variations of the primary caused by the gravity of the companion,
and measure gravity darkening. We detect the companion with interferometric
observations obtained with the Michigan InfraRed Combiner (MIRC) at Georgia
State University's Center for High Angular Resolution Astronomy (CHARA) Array
with a primary-to-secondary H-band flux ratio of 270+/-70. A radial velocity
curve of the companion was obtained with spectra from the Tillinghast Reflector
Echelle Spectrograph (TRES) on the 1.5-m Tillinghast Reflector at Fred Lawrence
Whipple Observatory (FLWO). We additionally use new observations from the
Tennessee State University Automated Spectroscopic and Photometric Telescopes
(AST and APT, respectively). From our orbit, we determine model-independent
masses of the components (M_1 = 1.28 +/- 0.07 M_Sun, M_2 = 0.73 +/- 0.03
M_Sun), and estimate a system age of 5 -/+ 1 Gyr. An average of the 27-year APT
light curve of sigma Gem folded over the orbital period (P = 19.6027 +/- 0.0005
days) reveals a quasi-sinusoidal signature, which has previously been
attributed to active longitudes 180 deg apart on the surface of sigma Gem. With
the component masses, diameters, and orbit, we find that the predicted light
curve for ellipsoidal variations due to the primary star partially filling its
Roche lobe potential matches well with the observed average light curve,
offering a compelling alternative explanation to the active longitudes
hypothesis. Measuring gravity darkening from the light curve gives beta < 0.1,
a value slightly lower than that expected from recent theory.Comment: Accepted to ApJ, 11 pages, 6 figures, 8 table
Insulating and Conducting Phases of RbC60
Optical measurements were performed on thin films of RbC,
identified by X-ray diffraction as mostly material. The samples were
subjected to various heat treatments, including quenching and slow cooling from
400K. The dramatic increase in the transmission of the quenched samples, and
the relaxation towards the transmission observed in slow cooled samples
provides direct evidence for the existence of a metastable insulating phase.
Slow cooling results in a phase transition between two electrically conducting
phases.Comment: Minor revisions. Submitted to PRB, RevTeX 3.0 file, 2 postscript
figures included, ir_dop
Measuring the dark side (with weak lensing)
We introduce a convenient parametrization of dark energy models that is
general enough to include several modified gravity models and generalized forms
of dark energy. In particular we take into account the linear perturbation
growth factor, the anisotropic stress and the modified Poisson equation. We
discuss the sensitivity of large scale weak lensing surveys like the proposed
DUNE satellite to these parameters. We find that a large-scale weak-lensing
tomographic survey is able to easily distinguish the Dvali-Gabadadze-Porrati
model from LCDM and to determine the perturbation growth index to an absolute
error of 0.02-0.03.Comment: 19 pages, 11 figure
Carbonic anhydrase seven bundles filamentous actin and regulates dendritic spine morphology and density
Intracellular pH is a potent modulator of neuronal functions. By catalyzing (de)hydration of CO2, intracellular carbonic anhydrase (CA(i)) isoforms CA2 and CA7 contribute to neuronal pH buffering and dynamics. The presence of two highly active isoforms in neurons suggests that they may serve isozyme-specific functions unrelated to CO2-(de)hydration. Here, we show that CA7, unlike CA2, binds to filamentous actin, and its overexpression induces formation of thick actin bundles and membrane protrusions in fibroblasts. In CA7-overexpressing neurons, CA7 is enriched in dendritic spines, which leads to aberrant spine morphology. We identified amino acids unique to CA7 that are required for direct actin interactions, promoting actin filament bundling and spine targeting. Disruption of CA7 expression in neocortical neurons leads to higher spine density due to increased proportion of small spines. Thus, our work demonstrates highly distinct subcellular expression patterns of CA7 and CA2, and a novel, structural role of CA7.Peer reviewe
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