3,037 research outputs found

    Exploring the growth challenges of social enterprises: Identifying staffing, earnings-generation and communications as critical success factors

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    How best to support the sustainability and growth of social enterprises is important to multiple stakeholders (Cavusgil & Knight, 2015; Thompson, Mawson & Martin, 2017). Evidence highlights that social enterprises struggle to scale-up, as reflected by a majority of UK-based social enterprises failing to breakeven. This research studies over one hundred social enterprises to explore the reasons for ineffective scaling and to identify where the priorities and challenges lie in achieving success. Recent literature and the Bloom & Smith (2010) SCALERS model (Staffing; Communicating; Alliance-building; Lobbying; Earnings-generation; Replicating; and Stimulating market forces) are used to determine key issues. The findings indicate that the effective scaling and impact (Kim, 2015) of social enterprises is reliant on three critical success factors: Staffing; Earnings generation; and Communications. Social enterprises need to optimise the recruitment and deployment of employees and volunteers, bearing in mind that they are essential for the replication of successes and in building alliances with networks of stakeholders (Stam, Arzalanian & Elfring, 2014). A robust earnings generation model is essential and may require the development of innovative income streams. Effective staff and robust finances helping establish strong coalitions, joint-ventures and partnerships across the stakeholder spectrum

    Analysis of ultrasonic transducers with fractal architecture

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    Ultrasonic transducers composed of a periodic piezoelectric composite are generally accepted as the design of choice in many applications. Their architecture is normally very regular and this is due to manufacturing constraints rather than performance optimisation. Many of these manufacturing restrictions no longer hold due to new production methods such as computer controlled, laser cutting, and so there is now freedom to investigate new types of geometry. In this paper, the plane wave expansion model is utilised to investigate the behaviour of a transducer with a self-similar architecture. The Cantor set is utilised to design a 2-2 conguration, and a 1-3 conguration is investigated with a Sierpinski Carpet geometry

    Influencing decision-makers as the next step for entrepreneurship educators: lessons from entrepreneurship education in challenging economies

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    Based on research into the challenging and emerging economies of Peru and Egypt, this study explores how the potential role for entrepreneurship educators is evolving. Interviews and questionnaires with 70 participants from two strands of entrepreneurship, female entrepreneurship in Peru and social entrepreneurship in Egypt, are used to assess entrepreneurship in such challenging economies. Both regions, Latin America and Africa, need successes in entrepreneurship to help establish social, economic and political stability in their nation states. However, the relationship between entrepreneurship and national stability is complex and symbiotic, as national stabilities also help catalyse success in entrepreneurial and enterprise initiatives. The relevance of enterprise and entrepreneurial education and its impact on connected issues such as graduate attributes and employability is complex. This research indicates that, while entrepreneurship education is certainly an asset for individuals in terms of creating new ventures and in enhancing their employability, entrepreneurship educators should also focus on influencing the national decision-makers in challenging and emerging economies. This includes politicians, financiers and other leaders across the public, private and third-sectors of society, as it is often these individuals who create the necessary atmosphere and ethos for entrepreneurial initiatives to flourish

    Real-time assembly of ribonucleoprotein complexes on nascent RNA transcripts.

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    Cellular protein-RNA complexes assemble on nascent transcripts, but methods to observe transcription and protein binding in real time and at physiological concentrations are not available. Here, we report a single-molecule approach based on zero-mode waveguides that simultaneously tracks transcription progress and the binding of ribosomal protein S15 to nascent RNA transcripts during early ribosome biogenesis. We observe stable binding of S15 to single RNAs immediately after transcription for the majority of the transcripts at 35 °C but for less than half at 20 °C. The remaining transcripts exhibit either rapid and transient binding or are unable to bind S15, likely due to RNA misfolding. Our work establishes the foundation for studying transcription and its coupled co-transcriptional processes, including RNA folding, ligand binding, and enzymatic activity such as in coupling of transcription to splicing, ribosome assembly or translation

    Hypervelocity Stars from the Andromeda Galaxy

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    Hypervelocity stars (HVSs) discovered in the Milky Way (MW) halo are thought to be ejected from near the massive black hole (MBH) at the galactic centre. In this paper we investigate the spatial and velocity distributions of the HVSs which are expected to be similarly produced in the Andromeda galaxy (M31). We consider three different HVS production mechanisms: (i) the disruption of stellar binaries by the galactocentric MBH; (ii) the ejection of stars by an in-spiraling intermediate mass black hole; and (iii) the scattering of stars off a cluster of stellar-mass black holes orbiting around the MBH. While the first two mechanisms would produce large numbers of HVSs in M31, we show that the third mechanism would not be effective in M31. We numerically calculate 1.2*10^6 trajectories of HVSs from M31 within a simple model of the Local Group and hence infer the current distribution of these stars. Gravitational focusing of the HVSs by the MW and the diffuse Local Group medium leads to high densities of low mass (~ solar mass) M31 HVSs near the MW. Within the virialized MW halo, we expect there to be of order 1000 HVSs for the first mechanism and a few hundred HVSs for the second mechanism; many of these stars should have distinctively large approach velocities (< -500 km/s). In addition, we predict ~5 hypervelocity RGB stars within the M31 halo which could be identified observationally. Future MW astrometric surveys or searches for distant giants could thus find HVSs from M31.Comment: 14 pages, 6 figures, changed to match version accepted by MNRA

    Neuronal behaviors: A control perspective

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    The purpose of this tutorial is to introduce and analyze models of neurons from a control perspective and to show how recently developed analytical tools help to address important biological questions. A first objective is to review the basic modeling principles of neurophysiology in which neurons are modeled as equivalent nonlinear electrical circuits that capture their excitable properties. The specific architecture of the models is key to the tractability of their analysis: in spite of their high-dimensional and nonlinear nature, the model properties can be understood in terms of few canonical positive and negative feedback motifs localized in distinct timescales. We use this insight to shed light on a key problem in experimental neurophysiology, the challenge of understanding the sensitivity of neuronal behaviors to underlying parameters in empirically-derived models. Finally, we show how sensitivity analysis of neuronal excitability relates to robustness and regulation of neuronal behaviors.This paper presents research results of the Belgian Network DYSCO (Dynamical Systems, Control, and Optimization), funded by the Interuniversity Attraction Poles Programme, initiated by the Belgian State, Science Policy Office. G.D. is a Marie-Curie COFUND postdoctoral fellow at the University of Liege. Co-funded by the European Union. J.D. is supported by the F.R.S.-FNRS (Belgian Fund for Scientific Research. The scientific responsibility rests with its authors.This is the author accepted manuscript. The final version is available from IEEE via http://dx.doi.org/10.1109/CDC.2015.740249

    Nuclear alpha-clustering, superdeformation, and molecular resonances

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    Nuclear alpha-clustering has been the subject of intense study since the advent of heavy-ion accelerators. Looking back for more than 40 years we are able today to see the connection between quasimolecular resonances in heavy-ion collisions and extremely deformed states in light nuclei. For example superdeformed bands have been recently discovered in light N=Z nuclei such as 36^{36}Ar, 40^{40}Ca, 48^{48}Cr, and 56^{56}Ni by γ\gamma-ray spectroscopy. The search for strongly deformed shapes in N=Z nuclei is also the domain of charged-particle spectroscopy, and our experimental group at IReS Strasbourg has studied a number of these nuclei with the charged particle multidetector array {\sc Icare} at the {\sc Vivitron} Tandem facility in a systematical manner. Recently the search for γ\gamma-decays in 24^{24}Mg has been undertaken in a range of excitation energies where previously nuclear molecular resonances were found in 12^{12}C+12^{12}C collisions. The breakup reaction 24^{24}Mg+12+^{12}C has been investigated at Elab_{lab}(24^{24}Mg) = 130 MeV, an energy which corresponds to the appropriate excitation energy in 24^{24}Mg for which the 12^{12}C+12^{12}C resonance could be related to the breakup resonance. Very exclusive data were collected with the Binary Reaction Spectrometer in coincidence with {\sc Euroball IV} installed at the {\sc Vivitron}.Comment: 10 pages, 4 eps figures included. Invited Talk 10th Nuclear Physics Workshop Marie and Pierre Curie, Kazimierz Dolny Poland, Sep. 24-28, 2003; To be published in International Journal of Modern Physics

    Massive open star clusters using the VVV survey III: A young massive cluster at the far edge of the Galactic bar

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    Context: Young massive clusters are key to map the Milky Way's structure, and near-IR large area sky surveys have contributed strongly to the discovery of new obscured massive stellar clusters. Aims: We present the third article in a series of papers focused on young and massive clusters discovered in the VVV survey. This article is dedicated to the physical characterization of VVV CL086, using part of its OB-stellar population. Methods: We physically characterized the cluster using JHKSJHK_S near-infrared photometry from ESO public survey VVV images, using the VVV-SkZ pipeline, and near-infrared KK-band spectroscopy, following the methodology presented in the first article of the series. Results: Individual distances for two observed stars indicate that the cluster is located at the far edge of the Galactic bar. These stars, which are probable cluster members from the statistically field-star decontaminated CMD, have spectral types between O9 and B0V. According to our analysis, this young cluster (1.01.0 Myr << age <5.0< 5.0 Myr) is located at a distance of 116+511^{+5}_{-6} kpc, and we estimate a lower limit for the cluster total mass of (2.81.4+1.6)103M(2.8^{+1.6}_{-1.4})\cdot10^3 {M}_{\odot}. It is likely that the cluster contains even earlier and more massive stars.Comment: Accepted for publication as a Letter in A&

    Shot-noise-limited spin measurements in a pulsed molecular beam

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    Heavy diatomic molecules have been identified as good candidates for use in electron electric dipole moment (eEDM) searches. Suitable molecular species can be produced in pulsed beams, but with a total flux and/or temporal evolution that varies significantly from pulse to pulse. These variations can degrade the experimental sensitivity to changes in spin precession phase of an electri- cally polarized state, which is the observable of interest for an eEDM measurement. We present two methods for measurement of the phase that provide immunity to beam temporal variations, and make it possible to reach shot-noise-limited sensitivity. Each method employs rapid projection of the spin state onto both components of an orthonormal basis. We demonstrate both methods using the eEDM-sensitive H state of thorium monoxide (ThO), and use one of them to measure the magnetic moment of this state with increased accuracy relative to previous determinations.Comment: 12 pages, 6 figure
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